Senior Director, Clinical Operations, Global Clinical Vendor Contracts & Budgets Revolution MedicinesSenior Director, Clinical Operations, Global Clinical Vendor Contracts & BudgetsRedwood City, CaliforniaThe leadership role ensures alignment with strategic objectives, regulatory requirements, and study timelines as well as bringing deep expertise in managing complex trials, contract negotiations, budget development, risk management, and cross-functional collaboration to contribute to the highest quality with on time delivery of RevMed’s clinical studies. A member of the Clinical Operations team Leading the Contracts and Outsourcing for all vendor relationships within Clinical Development, the Sr Director Global Vendor Outsourcing will lead the strategic identification and selection process with the teams for vendors and CROs, including scope specifications for clinical programs, and will work closely with the Sr.
Senior Director, Clinical Operations, Global Clinical Vendor Contracts & Budgets Revolution Medicines IncSenior Director, Clinical Operations, Global Clinical Vendor Contracts & BudgetsRedwood City, CA$244,000–$305,000 / yearThe leadership role ensures alignment with strategic objectives, regulatory requirements, and study timelines as well as bringing deep expertise in managing complex trials, contract negotiations, budget development, risk management, and cross-functional collaboration to contribute to the highest quality with on time delivery of RevMed's clinical studies. A member of the Clinical Operations team Leading the Contracts and Outsourcing for all vendor relationships within Clinical Development, the Sr Director Global Vendor Outsourcing will lead the strategic identification and selection process with the teams for vendors and CROs, including scope specifications for clinical programs, and will work closely with the Sr.
Trial Master File Sr. Manager, Clinical Operations Maze TherapeuticsTrial Master File Sr. Manager, Clinical OperationsSouth San Francisco, CA$175,000–$215,000 / yearOur clinical pipeline is anchored by two small molecule programs: MZE829, an APOL1 inhibitor for patients with APOL1‑mediated kidney disease, and MZE782, which targets genetic drivers of disease in phenylketonuria (PKU) and chronic kidney disease. This role is ideal for an experienced TMF professional who thrives in a fast-paced biotech environment, enjoys building processes from the ground up, and is passionate about developing high-quality, inspection-ready Trial Master Files.
Clinical Operations Compliance Director (Biotechnology Oncology) Exelixis Inc.Clinical Operations Compliance Director (Biotechnology Oncology)Alameda, CA$179,500–$256,000 / yearBachelor's degree in related discipline and a minimum of 13 years of related experience; or, Master's degree in related discipline and a minimum of 11 years of related experience; or, Doctoral degree in related discipline and a minimum of 8 years of related experience; or, Equivalent combination of education and experience. The Director drives consistency in clinical trial execution, promotes proactive risk identification and mitigation, supports audit and inspection readiness, and enables continuous process improvement through analysis of compliance metrics, trends and operational data.
Senior Project Manager, Clinical Operations Maze TherapeuticsSenior Project Manager, Clinical OperationsSouth San Francisco, CA$181,000–$221,000 / yearThis position combines portfolio-level project management with strategic operational initiatives, partnering closely with Clinical Operations Study Leads, Oversight Directors, and cross-functional teams to support the successful execution of multiple clinical pharmacology studies, early-phase studies, Phase 2 studies, and Phase 3 development programs, In this role, you will facilitate cross-functional planning and communication, coordinate complex study execution activities across the clinical portfolio, and oversee key Clinical Operations initiatives that strengthen organizational capabilities, improve processes, and drive operational excellence. Clinical Operations Project Management Partner with Clinical Operations Study Leads and Oversight Directors to coordinate project management activities across multiple Phase 1, clinical pharmacology, Phase 2, and Phase 3 studies, ensuring alignment of timelines, milestones, dependencies, and cross-functional deliverables.
Senior Director, Clinical Operations (Biotech, Oncology) Exelixis Inc.Senior Director, Clinical Operations (Biotech, Oncology)Alameda, CA$246,000–$349,500 / yearAs a Senior Director, oversees large clinical programs and represents Clinical Operations on internal and external strategy teams, including Product Development Teams (PDTs) which entails accountability for the operational strategy and successful execution of all Clinical Development Plans related to your assigned programs, including financial accountability. Oversight of quality delivery by leading the Clinical Operations team to ensure excellence in operational planning and implementation; and being the escalation point for the program in Clinical Operations; ensuring inspection readiness at all times and having regular interactions with Study Delivery Leads involved in the program such that they are aware of issues / risks / successes with study delivery as they occur.
SCI Senior Director, Clinical Operations (Hybrid) Stanford UniversitySCI Senior Director, Clinical Operations (Hybrid)Stanford, CA$195,687–$293,100 / yearThe pay offered to a selected candidate will be determined based on factors such as (but not limited to) the scope and responsibilities of the position, the qualifications of the selected candidate, departmental budget availability, internal equity, geographic location, and external market pay for comparable jobs. Identify, clarify, and resolve issues with strategic impact and substantial significance, which may span multiple areas, using advanced clinical trials operations and Good Clinical Practice (GCP) knowledge requiring broad discretion and judgment.
NewSenior Manager / Associate Director, Clinical Operations Alto NeuroscienceSenior Manager / Associate Director, Clinical OperationsMountain View, CA$170,000–$185,000 / yearThe Senior Manager/Associate Director, Clinical Operations provides line management and functional oversight for a team of clinical trial staff spanning Clinical Trial Associate (CTA), Clinical Research Associate (CRA), Clinical Trial Manager (CTM), and Clinical Project Manager (CPM) levels. This role is responsible for staff development, workload/resource allocation across assigned studies or programs, and ensuring consistent quality and process adherence across the team, while individual contributors retain day-to-day accountability for their assigned trials.
Vice President, Clinical Operations Nuvation Bio, Inc.Vice President, Clinical OperationsRemote - SF, CARemote$335,000–$350,000 / yearWorks with Clinical Operations team on CRO/vendor qualification and selection processes for outsourced activities, including scope of services agreements, budgets with unit cost negotiation, clinical and translational operational plans, and detailed timelines, and ensure that high-performance expectations are met. Shapes the Clinical Operations strategy and translates the strategy into an operational risk management plan by identifying and appropriately escalating trial and program risks to the Clinical R&D leadership team and the Executive Committee.
NewClinical Study Operations Engineering Program Manager - Health Apple IncClinical Study Operations Engineering Program Manager - HealthSunnyvale, CAdegree in biomedical engineering or any engineering discipline, or equivalent 5+ years of direct experience in clinical project management, strategic partnerships, or clinical operations within Health or Technology Strong human research background with a comprehensive understanding of the end-to-end study lifecycle, GCP, and domestic/international regulations Proven track record of managing and onboarding global CROs and diverse external vendors Ability to knit together disparate sources of information into a strong strategic narrative and perform data analysis to drive measurable results Expert analytical and negotiation skills, adept at facilitating actions, resolving conflicts, and delivering crisp, effective communication to executive leadership Proven ability to project manage and oversee clinical data management activities, ensuring adequate resourcing, vendor compliance, and strict data integrity across the study lifecycle. Self starter and critical thinker with the ability to work autonomously, establish priorities, and thrive in a highly ambiguous, fast paced environment Superb communication skills including effective listening, clear and concise writing, and the ability to articulate complex project updates to executives Ability to be onsite; this role is a hybrid, in-person position Some travel is required, approximately 25%.Experience leveraging AI, digital platforms, or advanced analytics in clinical recruitment and study operations Direct experience strategizing and mapping clinical operations for OUS regions.
Vice President, Clinical Operations Nuvation Bio IncVice President, Clinical OperationsSan Francisco, CAWorks with Clinical Operations team on CRO/vendor qualification and selection processes for outsourced activities, including scope of services agreements, budgets with unit cost negotiation, clinical and translational operational plans, and detailed timelines, and ensure that high-performance expectations are met. Shapes the Clinical Operations strategy and translates the strategy into an operational risk management plan by identifying and appropriately escalating trial and program risks to the Clinical R&D leadership team and the Executive Committee.
Associate Director, Clinical Operations Structure Therapeutics IncAssociate Director, Clinical OperationsSouth San Francisco, CA$186,000–$220,000 / yearCross-Functional Collaboration: Work closely with Preclinical, Biostatistics, Data Management, Clinical Supplies, Safety/PV, and Medical Affairs teams to ensure seamless study execution and IMP accountability, including sample management and study plan reviews. The company's platform combines the latest advancements in visualization of molecular interactions, computational chemistry, and data integration to design orally available, superior small molecule medicines that overcome current limitations of biologic and peptide drugs.
Associate Director, Clinical Operations (SF Bay Area) Structure Therapeutics IncAssociate Director, Clinical Operations (SF Bay Area)South San Francisco, CA$186,000–$220,000 / yearCross-Functional Collaboration: Work closely with Preclinical, Biostatistics, Data Management, Clinical Supplies, Safety/PV, and Medical Affairs teams to ensure seamless study execution and IMP accountability, including sample management and study plan reviews. The company's platform combines the latest advancements in visualization of molecular interactions, computational chemistry, and data integration to design orally available, superior small molecule medicines that overcome current limitations of biologic and peptide drugs.
Executive Director Clinical Operations, Program Management (Cell Therapy) AstraZeneca PlcExecutive Director Clinical Operations, Program Management (Cell Therapy)San Francisco, CA$270,188.80–$405,283.20 / yearAccountabilities: Franchise Leadership: Clinical Operations Strategy: Define and implement short- and long-term clinical operations strategies across franchises, including therapeutic operating models, country footprint and site strategies, and consistent, deliverable operational clinical development plans. Cross-Functional Integration: Build deep partnerships with shared functions (Data Management, Vendor Management, Lab Management groups, Logistics, Manufacturing) to co-create and execute fit-for-purpose cell therapy strategies.
NewSenior Manager / Associate Director, Clinical Operations Alto Neuroscience IncSenior Manager / Associate Director, Clinical OperationsMountain View, CA$170,000–$185,000 / yearThe Senior Manager/Associate Director, Clinical Operations provides line management and functional oversight for a team of clinical trial staff spanning Clinical Trial Associate (CTA), Clinical Research Associate (CRA), Clinical Trial Manager (CTM), and Clinical Project Manager (CPM) levels. This role is responsible for staff development, workload/resource allocation across assigned studies or programs, and ensuring consistent quality and process adherence across the team, while individual contributors retain day-to-day accountability for their assigned trials.
Senior Director, Clinical Operations Compliance Management (GCP/Biotechnology/Oncology) Exelixis IncSenior Director, Clinical Operations Compliance Management (GCP/Biotechnology/Oncology)Alameda, CA$246,000–$349,500 / yearThe Senior Director of COCM is a key partner with our Quality Assurance team and other functional groups (including Clinical Development, Data Management, etc.) and is responsible for supporting inspection readiness activities, driving cross-study consistency in study execution and compliance with governing functional procedures and processes, and escalation of identified operational issues within development and of identified quality issues to QA. EDUCATION/EXPERIENCE/KNOWLEDGE & SKILLS: Education: Bachelor's degree in related discipline and a minimum of 15 years of related experience; or, Master's degree in related discipline and a minimum of 13 years of related experience; or, Doctoral degree in related discipline and a minimum of 12 years of related experience; or, Equivalent combination of education and experience.
Associate Clinical Operations Compliance Director (Biotechnology Oncology) Exelixis IncAssociate Clinical Operations Compliance Director (Biotechnology Oncology)Alameda, CA$168,500–$238,500 / yearThe Associate Clinical Operations Compliance Director is a key partner with our Quality Assurance team and other functional groups (including Clinical Development, Data Management, etc.) and will assist in supporting inspection readiness activities, driving cross-study consistency in study execution and compliance with governing functional procedures and processes, and escalation of identified operational issues within development and of identified quality issues to QA. Bachelor's degree in related discipline and a minimum of 11 years of related experience; or, Master's degree in related discipline and a minimum of 9 years of related experience; or, Doctoral degree in related discipline and a minimum of 5 years of related experience; or, Equivalent combination of education and experience.
Senior Manager/Associate Director Clinical Operations Lycia TherapeuticsSenior Manager/Associate Director Clinical OperationsSouth San Francisco, CARemote$169,000–$198,000 / yearAbility to manage in a consensus environment through teamwork, trust and shared expectations, influencing strategic direction of complex global clinical operations issues, solicit information, listen well, persuade others, make important decisions and shape outcomes. Build, develop and train internal staff and external vendors, structure department for enhancing efficiency, and create a highly engaged work environment for attracting and retaining highly qualified clinical operations professionals.
Clinical Operations Specialist UCSF Medical CenterClinical Operations SpecialistSan Francisco, CAZion Medical Center (outpatient, including 23-hour stays and the Pain Management Center), Benioff Children''s Hospital Oakland, the UCSF Orthopedic Institute and the Benioff Children''s, Betty Irene Moore Women''s and Bakar Cancer (NIH-designated Cancer Center) Hospitals in the Mission Bay neighborhood. In addition to the Moffitt-Long Hospital, very active units of the department exist at the Zuckerberg San Francisco General Hospital and Trauma Center (inpatient and outpatient, including a very active trauma service), San Francisco Veterans Affairs Medical Center (inpatient and outpatient), Mt.
NewDirector, Clinical Operations Rigel Pharmaceuticals, Inc.Director, Clinical OperationsSouth San Francisco, CA$203,000–$245,000 / yearExperience leading global clinical trials across Phase I through Phase III, including responsibility for study planning, start-up, enrollment, monitoring, execution, database readiness, closeout, and Trial Master File oversight. Employees designated as onsite or hybrid who reside within the local commuting area are expected to work onsite at Rigel’s South San Francisco headquarters during normal business hours each Wednesday and Thursday.