Principal Product Designer MoonpigPrincipal Product DesignerManchester, NHWe’re proud to have a number of employee-led groups driving this forward, including our LGBTQ+, Gender Balance, Neurodiversity and EMBRACE (Educating Myself for Better Racial Awareness and Cultural Enrichment) communities, plus our Group-wide EDI committee. Wellbeing First: Private healthcare (UK) and mental health support ️ Flexible Working & Time Off: Generous holidays, hybrid working (1-3 days in office, depending on role/team) & up to 20 days of international working.
Principal System Architect TE Connectivity plcPrincipal System ArchitectMarlborough, MARemote$177,800–$266,600 / yearDrive thought leadership by educating and influencing internal and external stakeholders, from executives and product teams to key decision-makers in customer organizations, on emerging industry trends, TE's technical capabilities, and high-value engineering solutions. Serve as the primary technical liaison for TE's customers, actively engaging with hyperscalers, OEMs, and system architects to gain deep insights into next-generation compute, AI, storage, and networking challenges.
Principal Scientist SanofiPrincipal ScientistWaltham, MA$122.25–$176.58 / hourThe Genomic Medicine Unit (GMU) CMC group at Sanofi is dedicated to the establishment of best-in-class manufacturing platforms to support development of life-changing advanced cell and gene therapy products, including recombinant AAV vectors, lentiviral vectors and cell therapy products. Main responsibilities: Lead scale-up activities from bench scale to pilot scale (200L-2000L), applying engineering principles (mixing, mass transfer, shear stress, dissolved oxygen control) to ensure process comparability at large scale.
Principal Scientist, Antibody Discovery and Engineering ModernaTXPrincipal Scientist, Antibody Discovery and EngineeringCambridge, MassachusettsThis individual will operate with a high degree of independence, scientific judgment, and cross-functional influence while partnering with antigen design, structural and computational biology, Immuno-oncology and Autoimmune Therapeutics research leadership, project teams, and external CRO partners. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Principal Scientist, Computational Protein Design ModernaTXPrincipal Scientist, Computational Protein DesignCambridge, MassachusettsWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. This individual will work in close partnership with structural biology, directed evolution, immunology, translational science, and program teams to advance platform innovation and therapeutic programs across Moderna’s Research and Early Development portfolio.
Principal Sales Engineer, SLED - East Zscaler IncPrincipal Sales Engineer, SLED - EastMARemote$175,875–$251,250 / yearThe range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position across all US locations and could be higher or lower based on a multitude of factors, including job-related skills, experience, and relevant education or training. Demonstrated ability to act as a Consultative AI Advisor, guiding customers through AI change management, including mapping manual business workflows to agentic AI systems and managing expectations around non-deterministic outputs.
Principal Scientist, mRNA-tLNP Analytical Development Kernal BiologicsPrincipal Scientist, mRNA-tLNP Analytical DevelopmentBoston, MassachusettsDevelop and qualify methods to characterize antibody–lipid bioconjugates and targeted LNPs, including conjugation efficiency, antibody-to-particle ratio and surface ligand density, free/unconjugated antibody, conjugate identity and integrity, and antigen-binding activity. Demonstrated expertise in developing analytical methods to test and characterize mRNA and LNP products, spanning both biophysical and biochemical techniques (particle size measurement, HPLC, LC-MS, CE, ELISA, qPCR, protein analysis, and in vitro potency assays).
Investment Principal, Public Markets Partner's CapitalInvestment Principal, Public MarketsBoston, MassachusettsThe primary goal of the Public Markets Research Team is to deliver high absolute and relative returns over the long-term by partnering with of top-tier managers and select direct investments. In addition to the above, you will, for variety, take on other activities and projects, which might include researching and improving our portfolio construction knowledge and approach, assisting with business development, or helping to develop our technological capabilities.
Senior/Principal Scientist Cell Based Potency Assay 3316 Takeda Development Center AmericasSenior/Principal Scientist Cell Based Potency AssayLexington, MassachusettsD. in cell biology, molecular biology, immunology, biochemistry, bioengineering, pharmaceutical sciences, statistics, biostatistics, or a related discipline with 3+ years of relevant experience for Senior Scientist or 7+ years for Principal Scientist; MS with 9+ years for Senior Scientist or 13+ years for Principal Scientist; or BS with 11+ years for Senior Scientist or 15+ years for Principal Scientist. Plan and coordinate work with departmental, cross-functional, and external stakeholders, including Process Development, Quality Control, contract testing laboratories, Analytical Sciences, Quality Assurance, Regulatory, and other Analytical Development teams.
Client Service Principal, Taxable Partner's CapitalClient Service Principal, TaxableBoston, MassachusettsHands-on experience servicing US taxable clients (HNW families and family offices), including multi-entity household structures, tax-aware investment operations, and coordination with external CPAs and trust & estate counsel. Proactively identify and mitigate potential risks related to client accounts, working internally to identify, assess, and mitigate risks associated with client accounts and operational processes.
Principal Engineer (Electrical) Fresenius Kabi AGPrincipal Engineer (Electrical)North Andover, MA$115,000–$135,000 / yearThis position is a technical role within the hardware development team contributing to new and existing electrical systems in Ivenix products to achieve performance goals and business objectives. Final pay determinations will depend on various factors, including, but not limited to experience level, education, knowledge, skills, and abilities.
Principal Data Strategy Analyst Liberty Mutual Holding Company IncPrincipal Data Strategy AnalystPortsmouth, NHDescription As a Principal Data Strategist within the Office of Data and Data Science team supporting People, Purpose, and Brand, you will be a driving force behind transforming our organization and supporting business goals through cutting-edge data initiatives. You'll not only manage impactful data projects but also develop and mature strategy practices to steer an overall data strategy vision alongside our Enterprise Data Practice partners.
Principal Product Manager, Search Scribd, IncPrincipal Product Manager, SearchBoston, MASuccess here means defining a compelling vision, crafting metrics that truly matter, and experimenting your way to breakthrough features that redefine search relevance and discovery - all in close partnership with Engineering, Analytics, Data Science, Design, and Machine Learning teams who turn strategy into production reality. Familiarity with modern ML operations tooling - from vector databases to end-to-end model-ops workflows (MLOps / LLMOps) - and the ability to collaborate with engineering teams that rely on these systems.
Principal IT Systems Administrator CarGurus IncPrincipal IT Systems AdministratorBoston, MA$113,000–$142,000 / yearNice to have Experience in a high-growth SaaS or technology company familiarity with CarGurus tools Okta Google WorkspaceM365 Jamf Intune and experience partnering with Security Engineering and GRC. Come join us for the ride Role overview The Principal IT Systems Administrator is the most senior individual contributor on the IT Systems team setting technical direction for core platforms endpoints networks and security within IT Operations.
Principal Data Scientist - Gen AI Xometry IncPrincipal Data Scientist - Gen AIWaltham, MA$200,000–$230,000 / yearIn this role, you will serve as a technical leader, owning a 12 month technical roadmap, driving large-scale cross-functional ML and AI initiatives, and setting the long-term scientific direction for AI-driven solutions that enhance Xometry''s service offerings. Generative AI Development: Develop and deploy generative AI models and large language models (LLMs) for multimodal document processing, focusing on extracting structured data from technical drawings, purchasing orders, and other complex documents.
Principal Scientist, TCR Optimization ModernaTXPrincipal Scientist, TCR OptimizationCambridge, MassachusettsWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. The role is well suited for a hands-on scientist who can execute complex experimental workflows, interpret multi-parameter datasets, and contribute to the generation of optimized TCR candidates with the potency, specificity, and developability required for therapeutic advancement.
NewPrincipal Scientist / Associate Director, Process Analytical Technology (PAT) Lead Terrestrial Bio IncPrincipal Scientist / Associate Director, Process Analytical Technology (PAT) LeadWoburn, MA$140,000–$180,000 / yearThis individual will own the PAT vision and strategy end-to-end identifying, developing, and integrating in-process analytical technologies including image analysis/machine vision, at-line spectroscopy (UV/Vis, NIR), and real-time process monitoring across the manufacturing lines. As a senior technical leader, this person will build and grow the PAT sub-function, shape the analytical control strategy, and drive the organization toward real-time release testing (RTRT) and Phase 3 IND readiness.
Principal Security Governance, Risk & Compliance Analyst CarGurus IncPrincipal Security Governance, Risk & Compliance AnalystBoston, MA$135,000–$168,000 / yearThe Principal GRC professional leads key initiatives across cyber risk management customer trust security compliance AI governance third-party risk and security policy helping scale security programs to support CarGurus continued growth. Come join us for the ride Role overview The Principal Information Security GRC Analyst serves as a strategic leader responsible for designing implementing and continuously improving CarGurus cybersecurity governance risk and compliance program.
Principal Front Office Engineer, Investment Innovation, Integration & Trading Liberty Mutual Holding Company IncPrincipal Front Office Engineer, Investment Innovation, Integration & TradingBoston, MAAs a Principal Front-Office Engineer, you will serve as the technical lead embedded within the Investment Innovation, Integration & Trading (I3T) team, driving design and implementation of small-scale proofs of concept and prototypes that support the fixed income portfolio, improve investment analysis, develop AI-enabled workflows, and enhance reporting systems & processes. You will partner closely with analysts and investment teams to enhance their day-to-day use of AI, helping them build artifacts in a more technically sound manner and building robust systems and tools that scale those prototypes into production-ready applications.
Lead Principal Applications Engineer PoL Definition Infineon Technologies AGLead Principal Applications Engineer PoL DefinitionMAAs a Lead Principal Applications Engineer PoL Definition on our Technical Marketing team, you''ll work hand-in-hand with our customers, enabling them to transform our products into cutting-edge designs, all while building long lasting partnerships that thrive on success. Collaborative and customer-centered, partnering across Marketing, FAEs, Sales, IC Design, and Product Development to drive successful outcomes; proactive in addressing complex design and customer challenges.