Aseptic Control Principal Scientist, MSAT Vertex PharmaceuticalsAseptic Control Principal Scientist, MSATBoston, MassachusettsThis aseptic processing SME will partner with stakeholders to define strategies for microbial control of activities such as gowning, facility monitoring programs (EM, Water, Gases, etc.), disinfectant efficacy, aseptic processing simulations, filtration, particulate control, risk assessments, and will ensure the control strategies comply with industry guidance. Work closely with colleagues in Process development to design and implement new technologies for aseptic filling of cell therapy drug products in novel device platforms; this includes working closely with Contract Development and Manufacturing Organizations (CDMOs) and engineering firms to design processes and equipment needed to perform aseptic filling operations in a GMP environment.
Principal System Engineer Full SpectrumPrincipal System EngineerWestborough, MassachusettsThe Opportunity: Strategic Leadership & Client Impact: In this high-visibility role, you serve as the primary technical interface for our clients, driving Software Systems Engineering for mission-critical medical device projects: Lead & Delegate: Manage project execution by aligning client needs with team tasks and deliverables. Safety Risk Analysis: Lead planning for complex software-driven medical devices, perform top-down hazard and harm assessment working with Full Spectrum clients’ clinical tam or medical director, performing bottom-up failure analysis (FMEA) and identifying potential risk to safety.
Principal Embedded System Security Engineer (Onsite - Marlborough, MA) Secret Clearance Required RTXPrincipal Embedded System Security Engineer (Onsite - Marlborough, MA) Secret Clearance RequiredMassachusettsThe ideal candidate will be skilled in requirement allocation and decomposition, analyzing system architectures, designing security features and principles, assessing security vulnerabilities (scanning), and formal cybersecurity test and evaluation (CT&E). Work with customers and internal stakeholders to define cybersecurity requirement decomposition, allocation, implementation, and verification utilizing system engineering practices; providing guidance and direction related to security technologies.
NewPrincipal Systems Engineer, Verification Engineer Onsite RTXPrincipal Systems Engineer, Verification Engineer OnsiteWoburn, MassachusettsActive and existing security clearance required on day 1 At RTX, the world’s largest aerospace and defense company, 185,000 great minds are united by purpose and inspired to make a difference solving the world’s most complex problems. Experience compiling, summarizing, and presenting data analysis to internal and external stakeholders, including program leadership and external customers and collaborating across engineering functions to drive performance and resolve issues.
NewPrincipal Radar Receiver / Exciter Integration & Test Engineer RTXPrincipal Radar Receiver / Exciter Integration & Test EngineerTewksbury, MassachusettsAbility to obtain INTERIM U.S. government issued security clearance is required prior to start date At RTX, the world's largest aerospace and defense company, 185,000 great minds are united by purpose and inspired to make a difference solving the world’s most complex problems. May require up to a one (1) year assignment at a different location, such as shipyard locations (i.e. Huntington Ingalls Industries (HII) Shipyard in Pascagoula, MS; Navy’s Land Based integration facility in Mount Laurel, NJ).
QC Senior/Principal Scientist, Analytical Method Validation GenezenQC Senior/Principal Scientist, Analytical Method ValidationLexington, MA$120,000–$160,000 / yearLead transfer and validate next generation analytical procedures for the testing of viral vectors, cell banks and gene therapy products in support of Genezen's services and commercial products in compliance with company policies and procedures and regulatory guidelines. Nearby Indianapolis is home to professional and college sports teams, the Indy 500, a growing art community and the world's largest children's museum--to name just a few reasons why this area is a great place to live.
Principal, Technology Strategy Advancement Humana IncPrincipal, Technology Strategy AdvancementBoston, MARemote$166,700–$229,200 / yearWork at Home Requirements: To ensure Home or Hybrid Home/Office employees' ability to work effectively, the self-provided internet service of Home or Hybrid Home/Office employees must meet the following criteria: At minimum, a download speed of 25 Mbps and an upload speed of 10 Mbps is required; wireless, wired cable or DSL connection is suggested. This role will partner across business, product, engineering, architecture, finance, portfolio, and delivery teams to translate business priorities into technology roadmap implications, investment themes, capability needs, scorecards, leadership decision points, and measurable outcomes.
NewPrincipal Programmer, Statistical Programming (Remote) Vertex PharmaceuticalsPrincipal Programmer, Statistical Programming (Remote)Boston, MassachusettsRemoteEngages with a variety of other functions, including Statistical Programmers, Biostatisticians, Data Management, and other departments engaged in providing data and submission-related activities, often at Senior Management levels. Solves complex clinical trial reporting problems and demonstrates technical proficiency and exercises judgment in supporting daily operations and ensuring that study tasks are completed accurately and in a timely manner.
NewPrincipal Software Engineer - PA172 Zoominfo Technologies IncPrincipal Software Engineer - PA172Waltham, MARemote$163,800–$257,400 / yearSkilled at designing and implementing LLM-powered systems such as RAG pipelines, agent frameworks (e.g., LangGraph), or intelligent workflows that reason across large datasets in real time. You'll be joining a team with a broad range of ambitious, technically deep projects-from APIs that process tens of billions of events per day, to new buyer intent algorithms powered by LLMs, to a unified B2B identity graph.
Principal Specialist, Contracts (Onsite) RTXPrincipal Specialist, Contracts (Onsite)Concord, MassachusettsActive and existing security clearance required after day 1 At RTX, the world's largest aerospace and defense company, 185,000 great minds are united by purpose and inspired to make a difference solving the world’s most complex problems. Primary responsibilities will include supporting key pursuits within the portfolio, collaborating with internal and external stakeholders, negotiating terms and conditions with Government and non-Government customers, and providing contractual guidance.
Principal Systems Engineer - Onsite in Cambridge MA RTXPrincipal Systems Engineer - Onsite in Cambridge MAMassachusettsIn this Systems Engineer role, you will perform and/or support the following activities: Core Systems Engineering: Develop requirements and algorithms, concepts of operations, system trades, and system interfaces. Model Based Systems Engineering (MBSE): Develop and maintain detailed SysML descriptive system models, linking and synchronization of requirements, and generate design documentation / views.
Principal, CFO Advisory Baker Tilly Advisory Group, LPPrincipal, CFO AdvisoryTewksbury, MassachusettsThis role is designed for an experienced advisor, auditor, consultant, or finance leader who combines a deep understanding of high-performing finance organizations and how the role of the Office of the CFO is evolving in response to growth, complexity, and rising stakeholder expectations with a proven ability to develop business, drive growth, build client relationships, and lead high-performing teams. Baker Tilly Advisory Group, LP and Baker Tilly US, LLP, trading as Baker Tilly, are independent members of Baker Tilly International, a worldwide network of independent accounting and business advisory firms in 141 territories, with 43,000 professionals and a combined worldwide revenue of $5.2 billion.
Principal Product Configuration Management Engineer RTXPrincipal Product Configuration Management EngineerWoburn, MassachusettsThe term 'Digital Product' (DP) refers to, but is not limited to, the following software types and their associated data and documentation: embedded (tactical) software, applications, Built-in Test (BIT) software, reprogramming tools, simulation software, test equipment, configurable logic, Application-Specific Integrated Circuit (ASIC) design, analytical tools used to formally qualify deliverable artifacts, Model Based Systems Engineering (MBSE) system models or related artifacts, Free Open Source Software (FOSS), and Commercial Off-The-Shelf (COTS) software. Ability to obtain INTERIM U.S. government issued security clearance is required prior to start date At RTX, the world's largest aerospace and defense company, 185,000 great minds are united by purpose and inspired to make a difference solving the world’s most complex problems.
Principal Hardware Design Engineer RTXPrincipal Hardware Design EngineerTewksbury, MassachusettsThese design efforts will include collaboration with systems engineers, mechanical engineers, manufacturing engineers, and other electrical engineers to perform design trades and requirements flow down, perform electrical analysis, develop test plans, and ultimately to deliver working hardware that meets program requirements. Ability to obtain INTERIM U.S. government issued security clearance is required prior to start date At RTX, the world's largest aerospace and defense company, 185,000 great minds are united by purpose and inspired to make a difference solving the world’s most complex problems.
Senior Principal HPC Administrator (High Performance Computing) Northeast US locations, Hybrid RTXSenior Principal HPC Administrator (High Performance Computing) Northeast US locations, HybridConcord, MassachusettsThis High-Performance Computing (HPC) senior principal candidate will provide Raytheon Digital Technology High Performance Computing Administration in a heterogeneous Microsoft Windows and Red Hat Enterprise Linux environment. Must be able to obtain required Department of Defense Directive (DoDD) 8140 / 8570 Certification requirements (CompTIA Security+ CE or equivalent certification and an Operating System Certification) within 6 months of hire date.
Generator Systems Principal Electrical Engineer RTXGenerator Systems Principal Electrical EngineerMassachusettsThe department is responsible for design engineering, product and production support in the following areas: Electric Generator controls & operation engineering for wound-field synchronous generators and excitation controls for both stationery and mobile applications in the range of 30 kW to 3000 kW. Control Systems – Servo Control Systems, Motor/Power/Process Control, Digital Feedback Systems, Design of systems using MATLAB Simulink for power system simulations.
Principal Embedded Software Engineer Third PolePrincipal Embedded Software EngineerWaltham, MassachusettsThe Principal Software Engineer provides expertise in the design, development, characterization, and testing of complex software/firmware used to drive and manage complex electromechanical medical devices. 10+ years Software Engineering experience in the design and development of complex, real time software driven electromechanical Class II medical devices in C and C++; Class III experience preferred.
Principal Scientist, Separation Methods Expert, Analytical Science And Technology (As&T), Vertex Pharmaceuticals (Boston) Vertex Pharmaceuticals, IncPrincipal Scientist, Separation Methods Expert, Analytical Science And Technology (As&T), Vertex Pharmaceuticals (Boston)Boston, MA$138,400–$207,600 / yearAdditionally, the principal scientist will partner closely with all stakeholders, and with contract testing sites establishing partnerships to ensure compliance with cGMP and Quality Management systems for the global network to deliver our medicines to patients effectively. General Summary: The Analytical Science and Technology (AS&T) Principal Scientist, Separation Method Expert, will be responsible for providing scientific and technical expertise within and across functional areas for late-stage & commercial methods and vendor management.
Principal Decision Intelligence Engineer HumanaPrincipal Decision Intelligence EngineerBoston, MassachusettsRemoteWork at Home Requirements: To ensure Home or Hybrid Home/Office employees’ ability to work effectively, the self-provided internet service of Home or Hybrid Home/Office employees must meet the following criteria: At minimum, a download speed of 25 Mbps and an upload speed of 10 Mbps is required; wireless, wired cable or DSL connection is suggested. The pay range may be higher or lower based on geographic location and individual pay will vary based on demonstrated job related skills, knowledge, experience, education, certifications, etc.$187,900 - $258,500 per yearThis job is eligible for a bonus incentive plan.
Principal Software Engineer, Full Stack Cambridge Mobile TelematicsPrincipal Software Engineer, Full StackCambridge, MA$167,200–$209,000 / yearWe are seeking an experienced Principal Software Engineer to lead complex projects, and mentor teams in building scalable and reliable full-stack solutions. Recognized innovator in mobility AI, earning top honors including the TIME Industry Leader in AI, a Gold Edison Award, and the Artificial Intelligence Excellence Award for AI for Social Good.