181 Results for

Principal Jobs in Mansfield, MA

Jobs

Quincy, MA13 days ago

$165,500–$234,700

Saab Inc., Autonomous and Undersea Systems division is seeking an innovative and experienced Principal Mechanical Engineer to guide others on technical teams in capturing, understanding, and implementing product design requirements for autonomous Unmanned Surface/Underwater Vehicles (aUSVs/aUUVs, AUVs) and Remotely Operated Vehicles (ROVs). Demonstrated performance and expertise in the elements of mechanical design, such as analysis and implementation of requirements, developing design concepts, evaluating designs, technical and design reviews.

New!

Cambridge, MA1 day ago

Remote

Full-time
Employee

A successful candidate will assist ASIC development through creating custom analog layouts, floor planning entire chips, high level problem solving, and executing tape outs. ¿ Perform or guide physical layout, including floor-planning, and simulate circuits using extracted parasitic, contribute to design-for-test development.

Boston, MA9 days ago

Mentor and Scale Field Teams: Act as a thought leader within the organization, mentoring Solutions Consultants and Forward Deployed Engineers and helping to evolve and refine our AI solution delivery best practices. • Influence Product and GTM Strategy: Collaborate closely with product and engineering teams to relay field insights, identify gaps in our prebuilt agent inventory, and influence the product roadmap based on strategic customer needs.

Boston, MA11 days ago

Drive design and implementation of small-scale applications and proof of concepts to improve risk analysis, develop AI-enabled workflows, and enhance reporting systems and processes. Work closely with risk analysts and investment teams to build robust systems and tools that power risk infrastructure, analytics, and decision-ready reporting.

Boston, MA11 days ago

New!

Boston, MAToday

$162,773.52–$207,541.52

A management role that supervises employees focusing on tactical, operational activities within a specified area, with the majority of time spent overseeing area of responsibility, planning, prioritizing and/or directing the responsibilities of employees. Individual offers are determined using a comprehensive approach that considers relevant experience, certifications, education, skills, and internal equity to ensure compensation is fair, consistent, and aligned with our business goals.

Lancaster, MA30+ days ago

Must assist in enforcing the school code of conduct, testing and assessment programs, preparation of student and class schedules, assist all custodial, cafeteria, and other support services, assist in all curriculum matters. Assist parents through prompt communication and support for the purpose of impacting and improving students' academic performance.

Boston, MA30+ days ago

Assists the administration in implementing all policies and rules governing student life and conduct, and for the classroom, develops reasonable rules of classroom behavior and procedure, and maintains order in the classroom in a fair and just manner. Employs a variety of instructional techniques and instructional media, consistent with the physical limitations of the location provided and the needs and capabilities of the individuals or student groups involved.

Boston, MA30+ days ago

General Description: Under the general supervision, serves as secretary to the principal or headmaster of a school; performs complex clerical work requiring exercise of independent judgment. Email: hiringprocess@bostonpublicschools.org.

Boston, MA30+ days ago

Full-time

ODAIA's SaaS platform transforms complex data into predictive, personalized insights, enabling commercial leaders to understand their customers, anticipate prescribing behaviors, and make the informed, strategic decisions that bring therapies to patients faster. A proven track record of building successful partnerships, advising commercial pharma executives, leading high-stakes conversations and influencing multi-million dollar commercial investment decisions through data-driven storytelling.

Natick, Massachusetts30+ days ago

$200,000–$300,000 Per Year

Lancaster, MA30+ days ago

The job of Principal - Elementary was estabished for the purpose/s of providing support to the instructional process with specific responsibility for directing overall site operations, services and staff at an elementary school; providing information and serving as a resource to others; enforcing established policies and regulatory requirements; coordinating school activities and addressing issues, situations and/or problems that arise on campus or with enrolled students. Minimum requirements: Master's degree, or higher in job related area, two years of administrative experience as well as five (5) years as a teacher preferred.

Boston, MA30+ days ago

We focus all of our energy on discovering and solving customer and business problems, designing financially strong and defensible business models, activating growth engines, hiring world-class founding teams, and helping them thrive (and none of our energy on big-company b.s.). Led by co-founders who have both built unicorn real estate tech companies from scratch, we're a tight team of engineers, product managers, designers, and operators with decades of experience building products, teams, and businesses from startup to scale.

Boston, MA30+ days ago

$164,800–$206,000 Per Year

This role is the linchpin connecting cutting-edge technology with transformative workforce solutions, directly shaping products that empower businesses to hire, pay, and manage global teams seamlessly. Strategically leverage AI to create novel software solutions that tackle complex global workforce management and compliance issues, utilizing the Partner ecosystem to showcase and validate platform capabilities.

New!

Waltham, MA5 days ago

$120,000–$160,000 Per Year

Nova Biomedical is proud to be a global leader in osmolality testing and biotechnology and in vitro diagnostic (IVD) instrumentation, dedicated to advancing patient care and scientific discovery with a legacy that continues to shape the future of life sciences. With headquarters in Norwood and Waltham, Massachusetts, and a global team of nearly 2,000 employees, we’re building a collaborative, empowered culture grounded in shared values: Customer Centricity, Ingenuity, Ownership & Accountability, Collaboration, and Integrity.

New!

Waltham, MA5 days ago

$155,000–$190,000 Per Year

Nova Biomedical is proud to be a global leader in osmolality testing and biotechnology and in vitro diagnostic (IVD) instrumentation, dedicated to advancing patient care and scientific discovery with a legacy that continues to shape the future of life sciences. Lead system-level analysis and risk mitigation strategies related to battery thermal behavior and heat dissipation, including charging scenarios, environmental extremes, and long-term reliability to ensure patient safety and regulatory compliance.

Boston, MA28 days ago

$150,000–$180,000 Per Year
Full-time

Client Details The client is an innovative connected‑fitness company that blends advanced hardware, immersive digital content, and intuitive software to deliver a premium at‑home training experience, while fully owning and leading the entire electrical design function across its product portfolio. The position owns the entire electrical engineering function, working closely with mechanical, firmware, and software teams to deliver high‑quality, scalable consumer products.

New!

Boston, MA3 days ago

$90–$95

Experience with DLP, Encryption, Tokenization & HSM-based Key ManagementNotePreferred Qualifications: Experience in financial services, telecom, or government sectors. Experience Needed: 15+ YearsKey Skills Required: 10+ years in Cybersecurity Architecture & Engineering.

Waltham, MA30+ days ago

Full-time

Working knowledge of advanced consulting methodologies, tools, and techniques – with focus on: leveraging AI, LLMs, and life sciences real-world data, for purposes such as patient finding, HCP segmentation, and other applications of advanced analytics, optimization of omnichannel plans, marketing mix, performance analytics and reporting related activities. 10+ years as a top performer within a top-tier biopharmaceutical / pharmaceutical strategy consulting firm serving industry leading clients and/or relevant experience with advanced analytics, omnichannel measurement, marketing analytics, and/or technology-enabled solutions within pharma and biotech.

Bedford / Hanscom AFB, Massachusetts21 days ago

$140,000–$150,000 Per Year

The Air Force Program Execution Office for PEO Electronic Systems (ES) has the collective Air Force Materiel Command (AFMC) mission responsibility to manage and execute the modernization, development, testing, production, fielding, and sustainment of the PEO Digital portfolio, which includes over 130 programs for the United States Air Force (USAF) and foreign allies. Astrion has an exciting opportunity for a PRINCIPAL LOGISTICS MANAGERproviding support to the Air Force Life Cycle Management Center (AFLCMC), PEO Electronic Systems (ES) located at HANSCOM AFB, MA.

Bedford / Hanscom AFB, Massachusetts30+ days ago

Command, Control, Communications, and Battle Management (C3BM) has been tasked with delivering an integrated Department of the Air Force (DAF) Battle Network providing resilient decision advantage and enabling the USAF, USSF, Joint, and Coalition Force to win against the pacing challenge. C3BM’s main efforts are Architecture and Systems Engineering (ASE), Operational Response Team (ORT), and multiple mission integration teams such as Air, Maritime and multiple acquisitions consisting of both the Advanced Battle Management System (ABMS) and Space.

Bedford / Hanscom AFB, Massachusetts30+ days ago

Astrion has an exciting opportunity for a Principal Data Links and Communications Engineerfor the EPASS Cyber and Networks Directorate (EPASS HN II) contract, supporting the Aerial Networks Division (AFLCMC/HNA) located at Hanscom AFB, MA. Support defining and documenting a set of Combat Net Radio (CNR) networking parameter configurations to provide the best balance between flexible implementation of capability and implementation impact on both existing and emerging weapon systems.

Boston, MA27 days ago

Remote

Full-time

We are a rapidly growing, Boston-based medical technology company using AI to help clinicians make more informed decisions on cardiovascular care - leading to better patient outcomes, improved quality of care, and reduced healthcare costs. Compensation will be influenced by a wide array of factors including but not limited to internal pay equity, job-related knowledge, skills, education, relevant experience, certifications, and geography as outlined in the job description.

Waltham, MA15 days ago

We are looking for an experienced researcher to join our team as Principal Research Associate/Associate Scientist in the Molecular Assembly team, supporting our novel target identification and validation workflow in house. Excellent written and verbal communication skills, with the ability to document experiments in an organized and timely fashion and to present scientific data to coworkers.

Boston, MA27 days ago

$150,000–$180,000 Per Year

The client is an innovative connected‑fitness company that blends advanced hardware, immersive digital content, and intuitive software to deliver a premium at‑home training experience, while fully owning and leading the entire electrical design function across its product portfolio. The position owns the entire electrical engineering function, working closely with mechanical, firmware, and software teams to deliver high‑quality, scalable consumer products.

Cambridge Crossing, MA30+ days ago

$156,180–$189,252 Per Year

Hands-on experience using various cell line and PDX mouse models, humanized mouse models, admixture xenografts, orthotopic models to execute in vivo workflows enabling candidate selection for early clinical development is highly desired. Working closely with project teams and key stakeholders, lead the development of in vivo strategies from target concept to Proof of Concept in patients, applying scientific and technical skills and functional knowledge to complex projects.

Cambridge, MA30+ days ago

$145,320–$176,100 Per Year

Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. This role offers the opportunity to drive scientific innovation and shape the strategic direction of novel immunotherapy development at BMS in a highly collaborative environment that is guided by strong science and an enduring drive to benefit patients with cancer.

Cambridge, MA30+ days ago

You will also pioneer the integration of state-of-the-art AI techniques into real-world biologics pipelines, working closely with wet-lab scientists, bioinformaticians, protein engineers, and drug discovery program teams . Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Cambridge, MA30+ days ago

$152,730–$185,100 Per Year

In this role, you will represent the Dev DMPK function on cross-functional development project teams; oversee developmental drug metabolism and disposition, and non-clinical pharmacokinetics activities of multiple projects; be responsible for preparation of regulatory dossier / submissions; and assist in developing strategy for the group. Within the Pharmaceutical Candidate Optimization (PCO) organization at BMS, the Development DMPK Team provides ADME (absorption, distribution, metabolism, and excretion), DDI (drug-drug interactions) and PK (pharmacokinetics) support for all pipeline assets throughout clinical development, from candidate nomination through registration and lifecycle management.

Cambridge, MA30+ days ago

$184,720–$223,800 Per Year

The role of Senior Principal Scientist within Discovery Biotherapeutics, Selection Technologies involves leading a high-performing team that is responsible for conducting selections using in vitro display platforms such as yeast and mRNA display to discover binders against targets of interest. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility.

Cambridge, MA30+ days ago

$181,930–$220,500 Per Year

Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Cambridge Crossing, MA30+ days ago

$166,770–$202,086 Per Year

Hands on experience analyzing and integrating high-dimensional molecular datasets such as multi-omics (RNA-seq, ATAC-seq, proteomics, ChIP-seq/CUT&RUN ), single cell (CITE-seq, scATAC-seq, perturb-seq) and spatial profiling (Visium, GeoMx, CosMX ). We seek a creative and passionate computational scientist to join the Neuroscience, Immunology, and Cardiovascular (NIC) discovery team within Informatics and Predictive Sciences, a globally distributed group driving innovative computational research for discovery and early development.

Cambridge, MA30+ days ago

$160,060–$193,900 Per Year

Key responsibility of this role is to effectively collaborate with a cross functional team of asset scientists with deep disease, drug development and business knowledge to help drive an overall translational strategy, working closely with discovery and early development teams, late clinical development as well as with our team of laboratory scientists. + Leads small and large collaborations with academia and industry partners to identify biobanks, clinical trials and existing databases to collate multi-parameter genomic, immune and clinical datasets to mine for novel biomarkers of unmet need patients in conjunction with computational biologists, data scientists and statisticians.

Boston, MA30+ days ago

$201,600–$322,560 Per Year

From the moment a product team submits a new SKU request to the moment it is live in the price book and available to quote, you are the cross-functional orchestrator - working in lockstep with Product, Finance/FP&A, Commercial Operations (Quoting), Supply Chain, Operations, Legal, and IT. Own and operate the end-to-end NPI workflow for all SKU types (hardware, software, services) - from initial SKU submission by product team through cross-functional review cycles and Ready-to-Quote and Ready-to-Ship stages.

Cambridge, MA14 days ago

$78–$83.50 Per Hour

Key ResponsibilitiesLead development of cell-based assays to evaluate and rank multi-epitope mRNA construct designs (e.g., expression/presentation proxies, antigen-specific T cell activation, breadth/competition effects). We are seeking a highly motivated Principal Scientist to lead the development of scalable, cell-based assay platforms for evaluating and ranking multi-epitope mRNA construct designs in a high-throughput environment.

Bedford / Hanscom AFB, Massachusetts24 days ago

$150,000–$180,000 Per Year

Prepare technical documentation to define and recommend system/subsystem characteristics; produce management reports and technical presentations for planning, implementation, and corrective actions. Conduct program portfolio reviews to evaluate/recommend alternative plans, improve engineering processes, sustain program baselines, and validate system-level performance in accordance with specifications.

Bedford / Hanscom AFB, Massachusetts30+ days ago

$140,000–$150,000 Per Year

C3BM’s main efforts are Architecture and Systems Engineering (ASE), Operational Response Team (ORT), and multiple mission integration teams such as Air, Maritime and multiple acquisitions consisting of both the Advanced Battle Management System (ABMS) and Space. Command, Control, Communications, and Battle Management (C3BM) has been tasked with delivering an integrated Department of the Air Force (DAF) Battle Network providing resilient decision advantage and enabling the USAF, USSF, Joint, and Coalition Force to win against the pacing challenge.

Bedford / Hanscom AFB, Massachusetts14 days ago

The BMC Remedy Architect Principal position is located at Hanscom AFB, MA and focuses on providing acquisition program management support for Cyberspace Security and Control System (CSCS) programs. Defines, writes, and delivers specifications, user guides, and architecture and methodology as appropriate to meet project deadlines.

Providence, Rhode Island13 days ago

Bristol, Bristol29 days ago

£47,410–£54,210

Known internally as a Principal Geotechnical Engineer, you will: Provide specialist technical expertise to identify risks and shape early solutions for renewals and improvement schemes, in line with agreed methodologies considering new techniques, materials, buildability and costs. We address over 39,000 customer enquiries every month, plan and deliver all maintenance activities on the network, drive efficiencies and improvements across our systems and roads, and respond to incidents across 4,500 miles of motorways and major A-roads that we manage.

Bristol, Bristol12 days ago

£55,810–£66,690

Our Digital Lab designs and manages innovative data products and services in-house, while building external partnerships and increasing adoption of our digital assets to improve customer journeys, support the Strategic Road Network, and enable emerging technologies such as connected and autonomous vehicles. Build and lead senior stakeholder relationships across directorates, working with Directors and business leaders to manage service performance, prioritise demand, shape delivery backlogs, and influence future digital strategy both internally and externally.

Bristol, Bristol12 days ago

£55,810–£66,690

Our Digital Lab develops and manages innovative data products and services in-house, while building strategic external partnerships that increase adoption of our digital assets to improve customer journeys and support the efficient operation of the Strategic Road Network. Drive cross-directorate collaboration with product, data, and digital teams to maintain high-performing connected services, ensuring effective service management, delivery against KPIs, continuous improvement, and efficient operational performance.

Somerville, MA, MA30+ days ago

Full-time

Create conceptual techno-economic on-site energy solutions that appreciate and address the complex customer pain points of energy cost, sustainability, reliability, resilience, Capex constraints, and risk management (includes detailed data analysis, conceptual design, and modelling). The Principal Solutions Architect Engineer will also work with Schneider Electric (SE) Microgrid Competency Center (MGCC), Energy and Sustainability Services (ESS), and other SE business units as well as The Carlyle Group, various generation firms, and Engineer Procure Construct (EPC) firms.

Boston, MA30+ days ago

Remote

$119,000–$160,650 Per Year

We help extend the value of these assets, enabling our customers to embrace the potential of cloud and mobile computing, advanced analytics, and the innovations of tomorrow. + Demonstrated history as a consistent top performer selling software solutions to senior executives with quotas in excess of 3M, selling large transactions.

Boston, MA30+ days ago

$200,000–$230,000 Per Year

Our team of nearly 475 experts partners with 27 of the top 30 biopharmaceutical companies, the fastest-growing mid-caps, and cutting-edge emerging biotechs, including some of the biggest and most innovative brands. We partner with our clients to turn science into value by helping them understand the potential of their molecules, shaping their strategic plans, and allowing their decision-making to be the biggest differentiating factor in the success of their products.

Somerville, Massachusetts30+ days ago

$133,000–$165,000 Per Year

Lead and manage regulatory submissions, including FDA Q-submission, US 510(k)s submissions, Premarket Approvals (PMA) submissions, supplements, and reports, including Regulatory Body interactions. Regulatory Affairs Principal is responsible for developing and executing regulatory strategies, ensuring compliance with global regulations and leading the process to obtain and maintain market approval for DeepHealth’s high risk products, including AI technologies.

Somerville, Massachusetts30+ days ago

$130,000–$160,000 Per Year

Somerville, Massachusetts29 days ago

$200,000–$230,000 Per Year

The role drives the design, governance, and continuous improvement of automated security controls across all CI/CD pipelines and developer workflows—ensuring security is built in from design through production while enabling delivery that is fast, measurable, and audit-ready at scale. Advanced security certifications strongly preferred (CISSP, CSSLP, AWS Security Specialty, or equivalent); thought leadership through published work, conference presentations, or open-source contributions is a strong differentiator.

Cumberland, RI30+ days ago

$120

This hybrid role bridges traditional Microsoft Information Protection and compliance tools with modern AI-centric data security practices, including encryption for LLM pipelines, secure vector stores, and legacy data remediation. - Looking for experience with Snowflake, Microsoft Defender, DLP tools, Azure Purview and with a data engineering background that is operating in an oversight role or assisting a larger organization using those tools.

Lynn, MA30+ days ago

$104,000–$145,600 Per Year

A Principal MRB Engineer is needed to support the needs and goals of manufacturing teams with engineering substantiation reviews to determine the acceptability of aircraft engine hardware. Mentor and develop Junior Engineers who perform analysis to document acceptability of parts to include stresscalculations, tolerance stack ups, and leveraging of previous analysis.*

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Principal Jobs in Mansfield, MA

Jobs

Principal Mechanical EngineerSaab

Principal Analog Mixed Signal ASIC Layout EngineerGCR Professional Services

Principal AI Field ArchitectBoomi

Principal Front-Office EngineerAxelon Services Corporation

IT Principal Front-Office EngineerAxelon Services Corporation

Nursing Director – Hematology/Oncology & Bone Marrow TransplantTufts Medical Center

Assistant Principal (2026-2027 School Year)Rutherford County Schools

1/2 STEM Teacher & 1/2 Assistant Principal at Midway Middle (26-27 School Year)Roane County Schools

Guild - Principal Clerk School Secretary Grade 23 (SY25-26)Boston Public Schools

Managing Principal, AI-Driven Commercial EffectivenessOdaia Intelligence Inc.

Principal Scientist (M.D. or D.O.)Exponent Inc.

Pleasant Hill Elementary - PrincipalCumberland County School District

Principal Engineer - Stackpoint VenturesStackpoint Studio Inc

Principal Partner Platform AdvocateG-P

Principal Design Quality Engineer INova Biomedical

Principal Systems Engineer - POC DevicesNova Biomedical

Principal Electrical Engineer- Boston, MA- HybridMichael Page International

Principal Cybersecurity ArchitectTMS

Principal, AnalyticsTrinity Partners, LLC

Principal Logistics ManagerAstrion

Principal Software EngineerAstrion

Principal Data Links and Communications EngineerAstrion

Principal Platform EngineerElucid

Principal Research Associate/Associate Scientist, Molecular AssemblyTScan Therapeutics

Principal Electrical Engineer- Boston, MA- HybridMichael Page

Principal Scientist, In Vivo Pharmacology, Oncology Discovery BiologyBristol Myers Squibb

Principal Scientist, Cancer ImmunologyBristol Myers Squibb

Principal Scientist (AI/ML) - Predictive modeling, design and optimization for therapeutic antibodiesBristol Myers Squibb

Senior Principal Scientist, Development DMPKBristol Myers Squibb

Senior Principal Scientist, Discovery Biotherapeutics, Selection TechnologiesBristol Myers Squibb

Senior Principal Scientist- Immunology In Vivo PharmacologyBristol Myers Squibb

Principal Scientist Computational BiologyBristol Myers Squibb

Senior Principal Scientist/Associate Director, Translational Development, Lung Cancer Disease LeadBristol Myers Squibb

Principal NPI Program ManagerAxon

Principal ScientistAlpha Numeric

Principal Network EngineerAstrion

Principal Systems EngineerAstrion

BMC Remedy Application Developer PrincipalAstrion

Engineer II/III/Principal - Enterprise StandardsPPL Services Corporation

Principal Geotechnical EngineerNational Highways

Principal Machine Learning EngineerNational Highways

Principal Lab ManagerNational Highways

Principal Solutions Architect Engineer, MicrogridAlphaStruxure EmployeeCo, LLC

Principal Account ExecutiveRocket Software

Director / Associate Principal - Medical and Scientific Strategy ConsultingPrescient Healthcare Group

Sr Regulatory Affairs Principal AutonomousDeephealth

Sr Regulatory Affair PrincipalDeephealth

Principal Cloud Dev Ops EngineDeephealth

Data Security Principal ArchitectLancesoft

Principal MRB EngineerBelcan

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