Principal Software Engineer, Enterprise Scalability KlaviyoPrincipal Software Engineer, Enterprise ScalabilityBoston, MA$244,000–$366,000 / yearAI‑assisted scale engineering: AI‑driven anomaly detection reduces alert noise while improving signal; generative load testing and copilot runbooks are used in release/readiness checks for the top critical services; time‑to‑isolate regressions drops 20-30%. In addition to base salary, our total compensation package may include participation in the company's annual cash bonus plan, variable compensation (OTE) for sales and customer success roles, equity, sign-on payments, and a comprehensive range of health, welfare, and wellbeing benefits based on eligibility.
Sr Principal C++ Software Engineer CadenceSr Principal C++ Software EngineerBurlington, MA$140,000–$260,000 / yearThe team brings a unique focus to quality and innovation while designing state-of-the-art Cadence emulation products for use in developing today's multi-billion gate designs. You will work closely with a small team of exceptional engineers that are heavyweights in Cadence and EDA while developing the next generation Palladium emulation platform.
Senior Principal Ae-Rf Design Engineer CadenceSenior Principal Ae-Rf Design EngineerBurlington, MARequires a deep, specialized skill set: Building Blocks: Deep expertise in designing custom blocks such as Power Amplifiers (PAs), Low Noise Amplifiers (LNAs), mixers, and Voltage-Controlled Oscillators (VCOs). Validation: Extensive lab characterization experience utilizing high-frequency equipment like spectrum analyzers, VNAs, and probe stations.
Principal Software Engineer CadencePrincipal Software EngineerBurlington, MA$117,600–$218,400 / yearPlease note that the salary range is a guideline and compensation may vary based on factors such as qualifications, skill level, competencies and work location. BS with a minimum of 8 years of experience OR MS with a minimum of 5 years of experience OR PhD with a minimum of 3 years of experience.
Principal Scientist, Process Development (Expression Systems) ModernaTXPrincipal Scientist, Process Development (Expression Systems)Norwood, MassachusettsWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. PhD in Molecular Biology, Microbiology, Chemical/Biochemical Engineering, Biotechnology, Synthetic Biology, or a related discipline with 5+ years of relevant industry experience; or MS with 10+ years; or BS with 12+ years of relevant industry experience.
Principal Systems Architect (Ist, North Reading, MA) Teradyne, Inc.Principal Systems Architect (Ist, North Reading, MA)North Reading, MA$166,300–$266,100 / yearThe Teradyne's Integrated Systems Test (IST) Hardware Engineering team is seeking a highly motivated, energetic, technically driven System Engineer to deliver world class System Level Test solutions to our growing portfolio of customers. You will be responsible for interpreting business requirements and developing system requirements and architectures for Teradyne's IST product lines with a focus on new product development, as well as supporting the product line's goals around customer satisfaction, revenue, profitability and KPI's.
Principal Software Engineer - Compiler Development CadencePrincipal Software Engineer - Compiler DevelopmentBurlington, MA$117,600–$218,400 / yearBy offering Electronic Design Automation (EDA) tools, they enable engineers to simulate, verify, and optimize chip designs for various high-growth industries, including automotive, 5G, and hyperscale computing. Design Scalability: Architect compiler and simulator specifically tuned for complex AI designs, ensuring the engine can handle the massive replicated and parallel structures inherent in next-gen neural processing units (NPUs).
Principal Mechanical Engineer / Systems Engineer HaloBraidPrincipal Mechanical Engineer / Systems EngineerCambridge, MassachusettsThis is one of the hardest unsolved problems in robotics, applied to a $270B salon services industry, and integrating computer vision, compliant fiber manipulation, and novel mechanisms. Understand the full HaloBraid machine and its architecture: identify design, tolerance, assembly, serviceability, and dependency issues, and drive them to resolution.
Associate Principal Scientist, Clinical Research Merck & Co IncAssociate Principal Scientist, Clinical ResearchBoston, MA$142,400–$224,100 / yearTranslational Medicine (TMed) drives early clinical development of novel therapeutics by partnering with Discovery Sciences and Late-Stage Clinical Research to translate scientific discoveries into human proof-of-concept and advance the most promising candidates through the pipeline to patients. Leads and directs teams through key study planning, development, and execution activities, including program overviews, issue escalation and mitigation, senior management presentations, cross-functional governance meetings, and advisory meeting preparation.
Principal Research Associate, Pharmacology Chroma Medicine IncPrincipal Research Associate, PharmacologyBoston, MAGuided by a world-class team at the forefront of genetic medicine, founded by renowned pioneers in the field, and supported by top-tier investors, nChroma is redefining targeted in vivo genetic medicine with the initial goal of treating diseases affecting the liver, blood, cardiovascular and central nervous systems. Work in a busy research environment, which requires use of sharp objects, working around mechanical parts, working with or near known or unknown toxic or caustic chemicals and/or biological hazards, exposure to fumes and airborne particles.
Principal, Fund Controller Partner's CapitalPrincipal, Fund ControllerBoston, MassachusettsStrategic Partnership and Other: You will serve as a trusted advisor to global client CIOs, fund PMs, and research teams, ensuring fund finance considerations are integrated into broader strategic decisions. The Firm designs bespoke investment policies reflecting each client’s unique circumstances and implements investment solutions that aim to deliver strong returns with resilience across market cycles.
Principal Architect DigitalOcean LLCPrincipal ArchitectBoston, MARemote$235,200–$294,000 / yearIAM and KMS are the bedrock of trust at DigitalOcean; our services sit in the critical path of every request, authorizing billions of transactions per second with single-digit millisecond latency, and securing the cryptographic material that protects every customer workload on the platform. Evolve Key Management: Design and deliver a robust, multi-tenant KMS, including envelope encryption, customer-managed key patterns, and HSM-backed key material, that gives customers deep, fine-grained control over their data security posture.
Tax Principal - Life Sciences Baker Tilly Virchow Krause, LLPTax Principal - Life SciencesTewksbury, MAWhat you will do: Be a trusted leader of Baker Tilly's tax services, providing federal tax compliance and consulting services to commercial clients, positively impacting your clients through: Being a valued tax business advisor, leading client relationships on day-to-day tax matters with various clients ranging from middle market to multinational. Baker Tilly Advisory Group, LP and Baker Tilly US, LLP, trading as Baker Tilly, are independent members of Baker Tilly International, a worldwide network of independent accounting and business advisory firms in 141 territories, with 43,000 professionals and a combined worldwide revenue of $5.2 billion.
Principal Biologist ProximaPrincipal BiologistBoston, MassachusettsThis is a hands-on role: you'll run select assays in-house, manage CROs, and work closely with our structural proteomics data generation platform and computational teams, helping shape how our platform is applied to proximity-based drug discovery. You'll work across the full discovery arc, from target validation through hit ID, hit-to-lead, and lead optimization, owning the cellular pharmacology data that drives internal pipeline decisions and external partner deliverables.
Principal, Customer Success Folia HealthPrincipal, Customer SuccessBoston, MassachusettsYou will be the primary point of contact for sponsors after a program is signed, translating the insights our research produces into sponsor-usable outputs, guiding renewals and expansion, and making sure every program lands with scientific credibility. Partner closely with the Folia Research team including, research scientists and data scientists, in order to ensure sponsors experience Folia’s science with full scientific credibility and clear commercial relevance.
Senior Principal Scientist - Translational Muscle Biology UCBSenior Principal Scientist - Translational Muscle BiologyCambridge, MAThe candidate will bring hands-on scientific leadership to a matrixed team focused on identifying and building knowledge across pathobiological pathways and patient populations, including neuromuscular diseases related to nucleotide repeat expansions, genetic mutations, muscle atrophy, mitochondrial/lysosomal dysfunction, or inflammation. This is an opportunity for a scientific leader to advance portfolio projects and lead from the bench-exploring new biology and directly shaping the design, development, and execution of in vitro and in vivo models as well as cellular and biochemical assays for early drug discovery across multiple therapeutic programs and target discovery efforts.
Principal ML Ops Engineer PragmatikePrincipal ML Ops EngineerCambridge, MassachusettsYou will partner closely with AI researchers, GPU systems engineers, backend teams, and product stakeholders to ensure the companys large-scale AI systems are robust, efficient, automated, and production-grade . This is a high-impact, architecture-defining role where youll work across the entire model lifecycletraining, evaluation, deployment, observability, and continuous optimization.
Principal, Commercial Strategy Trinity PartnersPrincipal, Commercial StrategyWaltham, Massachusetts$188,000–$282,000 / yearThe Principal will also fulfill a highly strategic role in support of the firm’s success by: identifying innovative initiatives and implementing those; contributing as a strategic business partner to senior management; and developing short and long term goals and spearheading the implementation of related activities. Trinity’s salary bands account for a wide range of factors that are considered in making compensation decisions including but not limited to skill sets and market demand for skills; level of experience and training; specific qualifications, performance, time in role/company, geographic location, and other business and organizational needs.
Risk Advisory Services Principal Baker Tilly Virchow Krause, LLPRisk Advisory Services PrincipalTewksbury, MAWork closely with client executives and management teams to understand their businesses and assist in identifying and managing financial and operational risks within their business systems to ensure technology risks are managed: Develop in-depth knowledge of clients' businesses and industries by having direct client interaction while working on multiple aspects of an engagement. Baker Tilly Advisory Group, LP and Baker Tilly US, LLP, trading as Baker Tilly, are independent members of Baker Tilly International, a worldwide network of independent accounting and business advisory firms in 141 territories, with 43,000 professionals and a combined worldwide revenue of $5.2 billion.
Crypto Regulatory Principal, Membership Application Program Financial Industry Regulatory Authority, Inc.Crypto Regulatory Principal, Membership Application ProgramBoston, MAFINRA employees are required to disclose to FINRA all brokerage accounts that they maintain, and those in which they control trading or have a financial interest (including any trust account of which they are a trustee or beneficiary and all accounts of a spouse, domestic partner or minor child who lives with the employee) and to authorize their broker-dealers to provide FINRA with duplicate statements for all of those accounts. The role demonstrates expertise in managing applications, crypto trading platforms, market infrastructure, and distinctions between centralized exchanges, DeFi protocols, and traditional securities markets, utilizing advanced knowledge of custody of crypto asset securities, wallet creation, private key management, operational risk controls, and cybersecurity.