NewPrincipal Manufacturing Engineer Karman Holdings IncPrincipal Manufacturing Engineerhorsham, PAOur bow-to-stern capabilities include acoustic and sonar protection systems, propulsion systems, advanced composite structures, missile subsystems, canisters and launchers, and autonomous underwater vehicle subsystems. This role is part of our Maritime Defense Systems business, which delivers integrated solutions with decades of proven performance across submarine, surface, and autonomous naval platforms supporting high-priority national defense programs.
Principal Data Engineer Medical GuardianPrincipal Data EngineerPhiladelphia, PAThe Principal Data Engineer will own the design, delivery, and maturity of production-grade data pipelines and data platforms, with a primary emphasis on real-time streaming, IoT telemetry, Databricks, Azure, data services for APIs and microservices, and reliable data products for downstream consumption. The ideal candidate should be comfortable spending significant time working directly with Databricks, Spark, SQL, Python/PySpark, Azure services, streaming architectures, data quality frameworks, pipeline automation, CI/CD, and production troubleshooting.
Principal Analyst - Technology Resilience Forrester Research IncPrincipal Analyst - Technology ResiliencePhiladelphia, PA$141,000–$229,000 / yearThe Principal Analyst delivers research that encompasses: 1) modern technology resilience practices, skills, and culture; 2) drive research on key platforms, vendors and trends in data resilience, object storage, and recovery related markets; 3) brings the right mix of both strategic and technical delivery experiences; and 4) fosters a culture of collaboration across our research, sales, product, and customer success teams. Deep understanding of the following concepts and industry best practices: site reliability engineering (SRE), National Incident Management System (NIMS), the National Response Framework (NRF), availability zones, ISO 22301, NIST SP 800-34, blameless retrospectives, CAST, fault injection, proactive and continuous testing, business impact analysis, immutability, and tabletop exercises.
Principal Architect, Security Architecture Cencora IncPrincipal Architect, Security ArchitectureTrenton, NJ$110,500–$220,990 / yearThe Principal Architect - Cybersecurity works horizontally across the functional technology domains and the related security practices for Cloud, Infrastructure, Endpoint, Network, Storage; while also collaborating and representing core cybersecurity practices such as Identity & Access Management, Application Security, Data Security, AI Security, Cyber Defense, SaaS Security, OT/IoT, and emerging technologies, ensuring that security capabilities function as an integrated enterprise architecture rather than independent controls. Summary: The Principal Architect, Security Architecture is a senior individual-contributor and enterprise technical leadership role responsible for defining, governing, and advancing cybersecurity architecture across the enterprise in collaboration with other Principal Architects, Cybersecurity Architects, & Cybersecurity and domain engineering teams.
Principal Architect, Security Architecture Cencora, Inc.Principal Architect, Security ArchitectureWilmington, DE$110,500–$220,990 / yearThe Principal Architect- Cybersecurity works horizontally across the functional technology domains and the related security practices for Cloud, Infrastructure, Endpoint, Network, Storage; while also collaborating and representing core cybersecurity practices such as Identity & Access Management, Application Security, Data Security, AI Security, Cyber Defense, SaaS Security, OT/IoT, and emerging technologies, ensuring that security capabilities function as an integrated enterprise architecture rather than independent controls. Summary: The Principal Architect, Security Architecture is a senior individual-contributor and enterprise technical leadership role responsible for defining, governing, and advancing cybersecurity architecture across the enterprise in collaboration with other Principal Architects, Cybersecurity Architects, & Cybersecurity and domain engineering teams.
Principal Automation and Robotics Engineer 6084-Janssen Research & Development Legal EntityPrincipal Automation and Robotics EngineerSpring House, PennsylvaniaThe role establishes how robots, workcells, controls, sensors, safety systems, facilities, utilities, and vendor equipment should be designed and integrated so scientific workflows can scale across multiple automated platforms. Partnering with Principal Laboratory Automation Scientists, data/AI teams, IT/OT, EHS, facilities, quality, procurement, operations, and scientific leaders to ensure physical systems support scientific workflows and autonomous execution.
Experienced Structural Engineer | Associate Principal Wiss Janney Elstner AssociatesExperienced Structural Engineer | Associate PrincipalPhiladelphia, Pennsylvania$110,700–$184,500 / yearTechnical leadership, including applying sound engineering judgement and a deep understanding of governing codes, design guidelines, and industry practices; collaborating with interdisciplinary project teams across WJE as the structural engineering subject-matter expert (SME); leveraging your expertise for a variety of structural engineering projects, including the investigation, design, analysis, repair, and renovation of new and existing structures, construction materials, loading conditions, and construction types; preparing technically excellent client deliverables; providing high-quality reviews and oversight of work by others; and performing and training others in hands-on fieldwork. Minimum twenty years of relevant structural engineering industry experience, including technical and project management (e.g., failure/damage investigation; non-destructive evaluation and instrumentation; structural analysis and design for repair, retrofit, and rehabilitation of existing structures; evaluation of parking garage structures; and/or specialty consulting of new systems and materials from design through construction).
Associate Principal Scientist, Clinical Research Merck & Co IncAssociate Principal Scientist, Clinical ResearchWest Point, PA$142,400–$224,100 / yearTranslational Medicine (TMed) drives early clinical development of novel therapeutics by partnering with Discovery Sciences and Late-Stage Clinical Research to translate scientific discoveries into human proof-of-concept and advance the most promising candidates through the pipeline to patients. Leads and directs teams through key study planning, development, and execution activities, including program overviews, issue escalation and mitigation, senior management presentations, cross-functional governance meetings, and advisory meeting preparation.
Principal Scientist (Director) - Outcomes Research Merck & Co IncPrincipal Scientist (Director) - Outcomes ResearchNorth Wales, PA$190,800–$300,300 / yearPrimary Responsibilities: This position has primary responsibility for planning/managing a comprehensive program of real-world evidence and non-interventional research activities for in-line and pipeline products for lung cancers to meet the value evidence needs of clinicians, payers, policymakers, health technology assessment (HTA)/reimbursement agencies, and health systems globally. The following skills and knowledge are needed to be successful in this role: Decision making: Identifying and understanding problems and opportunities by gathering, analyzing and interpreting quantitative and qualitative information; choosing the best course of action by establishing clear decision criteria, generating and evaluating alternatives, and making timely decisions; taking action that is consistent with available facts and constraints and optimizes probable consequences.
Sr. Principal Scientist, Nonclinical Drug Safety Merck & Co IncSr. Principal Scientist, Nonclinical Drug SafetyWest Point, PA$190,800–$300,300 / yearStrategically influence nonclinical drug safety considerations for Immunology programs by providing drug development mentorship and partnering with Compound Leaders on time-critical matters, including nonclinical program design and toxicology study design, weight-of-evidence risk assessments, science-based waiver strategies, and integrated safety development plans that support clinical trials, global registration, and timely resolution of nonclinical development issues. Provide scientific and strategic oversight for Immunology candidates through close collaboration with Program Coordinators, Discovery Preclinical Leaders, Compound Leaders, and scientists across NDS and/or Preclinical Development, while ensuring strong partnership with key Research and Development Division functions, including Discovery, chemistry, regulatory affairs, translational medicine, clinical development, and CMC.
Principal Scientist, Drug Product Steriles Primary Packaging GSK plcPrincipal Scientist, Drug Product Steriles Primary PackagingCollegeville, PADrug Delivery, External Manufacturing, Medical Device Evaluation, Molecular Modeling, Pharmaceutical Formulations, Pharmacokinetics, Product Design, Product Management, Product Planning, Product Strategies, Quality by Design, Regulatory Filings, Stability Testing, Technology Transfer. Formulation Product Development: Understanding of actives, raw materials and their function and how they are brought together to form a stable, functioning product from prototype evaluation to commercial launch Job Family - Product Development: Manages or contributes to development of the company's products.
Principal Scientist (Scientific Director Level)- Nonclinical Drug Safety Merck & Co IncPrincipal Scientist (Scientific Director Level)- Nonclinical Drug SafetyWest Point, PA$176,200–$277,300 / yearThey are responsible for 1) providing risk assessments for targets, 2) de-risking strategies for discovery programs and 3) collaborating with NDS staff at other sites to execute on the appropriate studies to support selection of therapeutic targets, and the identification and development of new drug candidates. The Discovery Program Leader is responsible for defining and overseeing the NDS strategy for programs in all modalities (including small molecules, peptides, biologics and ADC programs) from Target Identification through to the approval of First-In-Human enabling GLP toxicity studies.
Associate Principal Scientist, Toxicology/Study Director Merck & Co IncAssociate Principal Scientist, Toxicology/Study DirectorWest Point, PA$142,400–$224,100 / yearRequired Skills: Animal Studies, Effective Written Communication, Evaluate Information, Good Laboratory Practices (GLPs), Oral Communications, Proactive Thinking, Study Directing, Study Monitoring, Teamwork, Toxicology. Our toxicologists provide scientific leadership in the design and overall conduct of in vivo studies and integrate the findings from all contributing scientists into reports that characterize the safety profile of drug candidates.
(Sr.) (Lead) (Principal) Energy Analyst/Engineer (II) PJM Interconnection LLC(Sr.) (Lead) (Principal) Energy Analyst/Engineer (II)PALead) Analyst/Engineer will support the Capacity Market Operations Department to successfully manage the $12 billion per year PJM Capacity Market that is used to ensure the reliability of the PJM system. The candidate will also help with the financial analysis of default minimum offer prices, default maximum offer prices, reference resource price used to determine the demand curve and power plant estimated net revenues.
Principal Scientist, Biostatistics, Late-Stage Clinical Development Merck & Co IncPrincipal Scientist, Biostatistics, Late-Stage Clinical DevelopmentNorth Wales, PA$190,800–$300,300 / yearIn BARDS (Biostatistics and Research Decision Sciences), a distinguished department within our company's renowned Research and Development division, quantitative scientists, in partnership with other subject matter experts, apply state-of-the art scientific methodologies and tools to enable the discovery, development, regulatory approval, manufacturing, and marketing of medical drugs and vaccines for the benefit of patients and global human health. Interacts with Clinical, Regulatory, Statistical Programming, Data Management, and our company Research Laboratories Scientists in designing and analyzing clinical trials, and in coordinating the statistical activities for clinical drug/vaccine projects.
Senior Principal Scientist, Veterinary Pathology Board Certified Merck & Co IncSenior Principal Scientist, Veterinary Pathology Board CertifiedWest Point, PA$231,900–$365,000 / yearRequired Skills: Analytical Assays, Analytical Assays, Assay Development, Biomedical Sciences, Biotechnology, Clinical Assays, Clinical Data Interpretation, Clinical Judgment, Clinical Safety, Drug Development, Drug Discovery Research, Drug Research, Histopathology, Immunochemistry, Immunology Research, Innovation, In Vitro Research, In Vivo Models, Laboratory Processes, Medical Biology, Molecular Diagnostic Techniques, Pathogenesis, Pharmaceutical Research, Post Mortem Analysis, Safety Pharmacology {+ 3 more}. Our Company's Research Laboratories nonclinical drug safety department at West Point, Pennsylvania site is seeking an experienced anatomic pathologist to join a highly collaborative team of scientists (12 anatomic pathologists, 3 clinical pathologists, and approximately 40 exceptional laboratory scientists), working at a GLP-compliant facility with state-of-the-art anatomic, molecular and clinical pathology laboratories.
Principal Engineer (US) Qurate Retail Group, Inc.Principal Engineer (US)PAQVC Group, Inc. is a Fortune 500 company with six leading retail brands - QVC, HSN, Ballard Designs, Frontgate, Garnet Hill and Grandin Road. If provided, salary ranges are a general guideline only, and actual salaries will vary and are based on factors such as a candidate's qualifications, skills, experience, and geographic location as well as business and market conditions.
Associate Principal Scientist, Statistical Programming, Late-Stage Oncology (Hybrid) Merck & Co IncAssociate Principal Scientist, Statistical Programming, Late-Stage Oncology (Hybrid)North Wales, PA$142,400–$224,100 / yearIn BARDS (Biostatistics and Research Decision Sciences), a distinguished department within our Company's renowned Research and Development division, quantitative scientists, in partnership with other subject matter experts, apply state-of-the art scientific methodologies and tools to enable the discovery, development, regulatory approval, manufacturing, and marketing of medical drugs and vaccines for the benefit of patients and global human health. Required Skills: Base SAS, Clinical Development, Data Management, Data Modeling, FDA Submissions, Influencing Skills, Oncology, Presentation Delivery, Process Improvements, Project Management, Project Planning, Resource Planning, Stakeholder Management, Statistical Programming, Strategic Planning, Strategic Thinking.
Associate Principal Scientist/Engineer, Medical Device and Combination Products, Analytical Merck & Co IncAssociate Principal Scientist/Engineer, Medical Device and Combination Products, AnalyticalWest Point, PA$142,400–$224,100 / yearRequired Skills: Analytical Chemistry, Computed Tomography (CT), Cross-Cultural Awareness, Design Validations, Design Verification, Design Verification Testing, Device Characterization, Interdisciplinary Collaboration, Materials Characterization, Mechanical Testing, Medical Devices Engineering, Microscopies, Professional Networking, Rheometry, Tensile Strength Testing, Tomography, X Ray Imaging. The role will naturally include substantial technical creative challenge for Device Characterization and more formal Design Verification, which includes development & validation of mechanical test methods as well as coordination & technical oversight for internal CPDA staff or external lab testing (where required) to meet project timelines and deliverables.
Principal Scientist, Stat. Programming - A&R Standards, Innovation (Hybrid) Merck & Co IncPrincipal Scientist, Stat. Programming - A&R Standards, Innovation (Hybrid)North Wales, PA$173,200–$272,600 / yearIn BARDS (Biostatistics and Research Decision Sciences), a distinguished department within our company's renowned Research and Development division, quantitative scientists, in partnership with other subject matter experts, apply state-of-the art scientific methodologies and tools to enable the discovery, development, regulatory approval, manufacturing, and marketing of medical drugs and vaccines for the benefit of patients and global human health. Superior knowledge and significant experience in setting strategy and developing analysis and reporting statistical programming deliverables (datasets, statistical analyses, report tables, and graphics) according to quality, compliance and timeliness requirements.