Principal Product Engineer, Data Applications Kairon HealthPrincipal Product Engineer, Data ApplicationsNew York, New YorkOur platform parses, normalizes, and connects data across fragmented systems (EHRs, payers, CRMs, and qualitative sources) so practice leaders can make clear, confident decisions that improve outcomes and drive sustainable growth. You’ll thrive here if you’re as excited about what you build as why you’re building it: an engineer who understands product trade-offs, can shape features from user requirements, and enjoys turning messy data into meaningful, elegant applications.
Principal Performance Java Test Enigineer BlockHiresPrincipal Performance Java Test EnigineerJersey City, New JerseyWe are uniquely positioned at the center of global trading activity, processing over 100 million financial transactions every day, pioneering industry-wide, post-trade solutions and maintaining multiple data and operating centers worldwide. This highly technical position is responsible for the performance engineering of DTCC distributed computing environments and providing analytical stress evaluations of applications/systems and service level compliance using statistical, analytical, and simulation methods.
Senior/Staff/Principal Backend Engineer, Platform & Data Ingestion Verana Health IncSenior/Staff/Principal Backend Engineer, Platform & Data IngestionNew York, NY$150,000–$236,000 / yearVerana Health, a digital health company that delivers quality drug lifecycle and medical practice insights from an exclusive real-world data network, recently secured a $150 million Series E led by Johnson & Johnson Innovation - JJDC, Inc. (JJDC) and Novo Growth, the growth-stage investment arm of Novo Holdings. Within the Oncology Platform, your work directly impacts patient care by dictating how fast and how cleanly raw medical documentation is unlocked and structured to support life-saving research and improving clinical outcomes.
Principal Software Engineer - Executive Director Post Trade Technology JPMorgan Chase & CoPrincipal Software Engineer - Executive Director Post Trade TechnologyJersey City, NJSets direction and governance for agentic AI-enabled engineering and SDLC/TLM automation within a technical area to drive measurable improvements in speed, quality, and operational outcomes (e.g., AI-orchestrated delivery workflows, release readiness controls, automated test modernization, and incident triage acceleration), while establishing guardrails for validation, security, resiliency, traceability, and reuse across teams. As a Principal Software Engineer at JPMorganChase within the Commercial & Investment Bank Post Trade Technology, you provide expertise and engineering excellence as an integral part of an agile team to enhance, build, and deliver trusted market-leading technology products in a secure, stable, and scalable way.
Sr. Principal, Product Manager - Agentic & Platform Smarsh, Inc.Sr. Principal, Product Manager - Agentic & PlatformNew York, NY$220,000–$240,000 / yearBuild the extensibility model: how sophisticated customers and external or agentic systems build on the platform, including developer-facing documentation and the packaging that frames what is a subscription tier, what is usage-based, and what justifies a premium price point. Define product requirements for agentic workflows such as review, analyst assist, auto-sampling, and automations, operating on the same behavioral data asset and audit trail as human users.
Senior Principal Architect - Application Platforms JPMorgan Chase & CoSenior Principal Architect - Application PlatformsJersey City, NJDeep enterprise expertise across Application & Collaboration Platforms Architecture areas including collaboration and communication ecosystems, document/content lifecycle management, multimedia toolchains, secure-by-design governance and compliance, integration/interoperability patterns, reliability and lifecycle operations, portfolio rationalization, financial/TCO decisioning, and executive-level change leadership. Leads reuse-first adoption of enterprise-authorized AI capabilities within the work environment to accelerate architecture analysis, option evaluation, and delivery of strategic global solutions, with human-in-the-loop validation and appropriate handling of sensitive data.
NewPrincipal Solution Sales Advisor Medidata Solutions IncPrincipal Solution Sales AdvisorNew York, NYRemote$116,250–$155,000 / yearCelebrating over 25 years of ground-breaking technological innovation across more than 38,000 trials and 12 million patients, Medidata offers industry-leading expertise, analytics-powered insights, and one of the largest clinical trial data sets in the industry. Support marketing teams in establishing and managing quarterly Product Marketing activities (including, but not limited to - white papers, press releases, search engine optimization, case studies, etc.).
Associate Principal Scientist, Upstream Development Merck & Co IncAssociate Principal Scientist, Upstream DevelopmentRahway, NJ$142,400–$224,100 / yearRequired Skills: Biodesign, Biodesign, Biological Engineering, Cell Cultures, Cell Line Development, Cell Physiology, Chemical Engineering, Clinical Trials, Computational Fluid Dynamics (CFD), Detail-Oriented, Downstream Process Development, Drug Delivery Technology, Drug Development, Expression Vectors, Interpersonal Relationships, Leading Project Teams, Mammalian Cell, Mammalian Cell Culture, Manufacturing Processes, Molecular Biology, Operational Efficiency, Pharmaceutical Formulations, Pharmaceutical Process Development, Physical Characterization, Stable Cell Lines {+ 1 more}. In this role, the successful candidate will work closely with a highly motivated team of Scientists and Engineers in the Upstream Process Development area and contribute to CMC development of our company's pipeline, playing an active role in the design, development, and optimization of cell culture processes and the transfer of processes to clinical and commercial manufacturing sites.
Principal E commerce & CRM Mitchell MartinPrincipal E commerce & CRMLong Island City, NY$53.90–$77 / hourBy applying for this job, you agree to receive AI-generated calls, text messages, and/or emails from Mitchell Martin Inc and its affiliates and contracted partners at various frequency through traditional and automated methods. This role involves hands-on performance measurement and attribution across digital platforms, requiring expertise in data analysis and reporting with advanced data management tools.
NewPrincipal Scientist, Clinical Biomarker, Immunology & Immuno-Oncology (Hematology) Legend Biotech USPrincipal Scientist, Clinical Biomarker, Immunology & Immuno-Oncology (Hematology)Somerset, New JerseyLeverage advanced single-cell technologies (e.g., scRNA-seq) to deeply profile immune cell compartments, particularly T-cell states and exhaustion markers, to inform patient stratification and biomarker hypotheses. Our research spans chimeric antigen receptor T-cell (CAR-T), T-cell receptor (TCR-T), natural killer (NK) cell-based therapies, and other emerging platforms designed to transform the treatment of serious diseases.
Principal AI Security Specialist - East Zscaler IncPrincipal AI Security Specialist - EastNJRemote$175,875–$251,250 / year10+ Years of Solutions Engineering Mastery: A proven track record in a customer-facing technical role (Sales Engineering, Solutions Architecture, or Technical Advisory) navigating complex, enterprise-level sales cycles. The range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position across all US locations and could be higher or lower based on a multitude of factors, including job-related skills, experience, and relevant education or training.
Principal Product Designer Gen Digital IncPrincipal Product DesignerNew York, NY$150,000–$180,000 / yearOur combined heritage is rooted in financial empowerment and cyber safety for the first digital generations, and today we deliver award-winning cybersecurity, online privacy, identity protection and financial wellness solutions to nearly 500 million users in more than 150 countries. We're looking for a Principal Product Designer with exceptional interaction and visual design craft and a strong track record of solving hard user and business problems in consumer products.
Principal Scientist - ADME - Site Based, Princeton, NJ Just-Evotec BiologicsPrincipal Scientist - ADME - Site Based, Princeton, NJPrinceton, New JerseyIn addition, as a visible leader in the group, utilizing excellent communication, organizational and technical skills, you will support the training and development of staff, improving the team’s knowledge and processes. Conduct in vitro ADME assays manually or using automated liquid handling system for completion in a fast-paced environment, while managing multiple projects to meet the timelines.
Senior/Staff/Principal SWE - OT Security Engineering AppGate Cybersecurity, Inc.Senior/Staff/Principal SWE - OT Security EngineeringNew York, NY$180,000–$275,000You'll work directly with the CTO and OT Technical Product Manager to take secure remote access for OT from concept to production deployment in real industrial environments - electric utilities navigating NERC CIP requirements, manufacturers managing third-party vendor access, and defense programs requiring CMMC-compliant remote access controls. We are open to candidates at the Senior level (hands-on engineer with deep OT remote-access experience) and Staff / Principal level (hands on technical leader who can own architecture and mentor as the team scales to 5–7 engineers).
Staff / Principal DevOps Engineer AppGate Cybersecurity, Inc.Staff / Principal DevOps EngineerNew York, NY$185,000–$270,000Observability from day one: Instrument monitoring, logging, and alerting across services and infrastructure using tools such as Prometheus, Grafana, and the ELK stack (Elasticsearch, Logstash, Kibana); define the SLOs, error budgets, and operational health metrics the team will trust. Security Best Practices: Implement security best practices across infrastructure and deployment workflows — secrets management, least-privilege access, certificate and key management, vulnerability remediation, and secure-by-default configuration — fitting for a company whose product is security.
Staff / Principal Data Engineer AppGate Cybersecurity, Inc.Staff / Principal Data EngineerNew York, NY$180,000–$270,000Build low-latency batch and streaming pipelines that ingest signals from internal and external sources, normalize them to a common schema, enrich them with context and serve model-ready data to the layers above. Extensive experience building and operating large-scale data platforms and data lakes, with comfort working at high data volumes.
Senior/Staff/Principal SWE- Observability Engineering AppGate Cybersecurity, Inc.Senior/Staff/Principal SWE- Observability EngineeringNew York, NY$180,000–$275,000Your engineering work will directly enable next-generation capabilities, including: • OpenTelemetry-Native Telemetry Fabric: Logs and distributed traces from clients, controllers, gateways, and connectors — all correlated by session, user, device, and trace ID across the full ZTNA flow. It emits high-fidelity, correlated telemetry across every AppGate component, is OpenTelemetry-native, engineered for 100M+ events per day, and designed to stream into Datadog, Splunk, Nexthink, Elastic, or any OTLP-compatible backend.
Senior/Staff/Principal AI/ML Engineer - Threat Detection Engineering AppGate Cybersecurity, Inc.Senior/Staff/Principal AI/ML Engineer - Threat Detection EngineeringNew York, NY$180,000–$275,000MLOps & Productionization: Experience building and operating scalable MLOps platforms for AI/ML systems, including model lifecycle management, CI/CD for ML pipelines, feature stores, automated retraining, model monitoring/drift detection, experiment tracking, and deployment orchestration using Kubernetes, MLflow, Kubeflow, SageMaker, or equivalent tooling in high-throughput production environments. • Your engineering work will directly enable next-generation capabilities, including: • Threat Detection Engine: Build advanced detections to identify threats early, including identity compromise, privilege escalation, impossible travel, and data exfiltration across identity, network, device, and session telemetry.
Principal - Platform Engineer Ampcus IncorporatedPrincipal - Platform EngineerWarren, NJRemote$77.64–$82.64 / hourThis strategic role will drive an Enterprise API & AI Security Modernization Program focused on transforming Azure API Management into a secure, scalable, and governed platform supporting Internal APIs, External APIs, AI Services, Large Language Models (LLMs), AI Agents, and future AI workloads. The ideal candidate will collaborate with Platform Engineering, Cloud Engineering, Information Security, Networking, Enterprise Architecture, and Application teams to build a secure, resilient, automated, and developer-friendly API platform.
Principal Engineer Software - Developer Experience, Backend (Chronosphere) Palo Alto NetworksPrincipal Engineer Software - Developer Experience, Backend (Chronosphere)New York City, New YorkRemoteFor candidates who receive an offer at the posted level, the starting base salary (for non-sales roles) or base salary + commission target (for sales/com-missioned roles) is expected to be the annual range listed below. Our highly reliable platform enables our customers to troubleshoot in real-time and harden system reliability through AI powered guided troubleshooting, contextualized data and elegant collaboration tools.