PREP is a 5-year cooperative agreement between NIST laboratories and participating PREP Universities to establish a collaborative research relationship between NIST and U.S. institutions of higher education in the following disciplines including (but may not be limited to) biochemistry, biological sciences, chemistry, computer science, engineering, electronics, materials science, mathematics, nanoscale science, neutron science, physical science, physics, and statistics. Research will explore the integration of superconducting nanowire single-photon detectors (SNSPDs) with photonic waveguides, with an emphasis on high-efficiency photon detection, device design and fabrication, optical coupling, cryogenic characterization, and integrated quantum photonic systems.