Research Technician Jobs in Massachusetts
Takeda
Boston, MA
Accountabilities: Generate data packages supporting candidate selection and asset characterization based on current in vitro methods including immortalized cell lines, primary cell cultures, and multicellular or organoid culture models, preferably models that recapitulate cellular cross-talk in fibroinflammatory or diseased tissues. The Gastrointestinal and Inflammation (GI2) Drug Discovery Unit at Takeda is building a new team of experienced, innovative, and collaborative researchers to deliver an industry-leading portfolio of drugs for various gastrointestinal, autoimmune, and inflammatory diseases with high unmet medical needs.
Takeda
Boston, MA
Contributes to the design and execution of in vivo experiments, independently conducts complex experiments, exercising judgment to evaluate various technical factors and achieve optimal solutions, analyze and interpret data, and present results to stakeholders; Knowledge of data analysis programs such as GraphPad PRISM, Microsoft Excel, FlowJo FACS analysis, Nanostring transcriptome analysis and Softmax Pro and/or other equivalent software ideal but not required. Proper handling and care of mice and other rodents, tumor implantation, general dosing (multiple routes – oral, IV, IP, SC), collection and analysis of blood and tissue samples; work schedule flexibility, including a commitment to work weekends, to ensure optimal dosing schedules on a project-specific need will be required.
Takeda
Boston, MA
The Gastrointestinal and Inflammation (GI2) Drug Discovery Unit at Takeda is building a new team of experienced, innovative, and collaborative researchers to deliver an industry-leading portfolio of drugs for various gastrointestinal, autoimmune, and inflammatory diseases with high unmet medical needs. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.
Takeda
Boston, MA
Join Takeda as a Director of Cell Therapy where you will lead a team responsible for designing and implementing in vitro pharmacological assays, using state-of-the-art technologies and methodologies, leading the discovery of novel Cell Therapy products, and contributing to the strategic direction of our Cell Therapy research programs. Cross-functional Collaboration: Collaborate closely with interdisciplinary discovery teams in a matrix format, including biologics engineering, biologics production, analytics, translational scientists, and preclinical development teams to advance discovery programs.
Takeda
Boston, MA
Join Takeda as a Director, Immunotherapy/ Immuno-Oncology, In Vitro Pharmacology where you will play a major role in the discovery of novel biologics, contributing to the strategic direction of our immunotherapy/ immune-oncology research programs. Excellent leadership, communication, and interpersonal skills, with the ability to lead a team and projects and collaborate effectively across disciplines, demonstrate enterprise leadership with an ability to influence without authority.
Takeda
Boston, MA
Global Biologics (GB) mission is the discovery of transformative, innovative Biologics therapeutics to support Takeda's pipeline and advance novel therapeutics into clinical development in Takeda's three therapeutic areas of interest: Oncology (immuno-oncology, cell therapies), Gastroenterology, and Neuroscience, The In Vitro Pharmacology group plays a crucial role in evaluating the biological activity of potential therapies, selecting candidates for preclinical and clinical development. How you will contribute: Functional leadership: Lead and innovate in the design, development, and execution of in vitro pharmacology assays to assess the biological activity, mechanism of action, and efficacy of novel biologic therapies targeting GI diseases, inflammation, and neurological disorders.
Takeda
Boston, MA
Lead a team responsible for the design, development and execution of state-of-the-art in vitro pharmacology assays to evaluate the biological activity, potency, efficacy, and mechanism of action of our novel therapeutics, utilizing cutting-edge technologies (e.g., complex cell-based assays, co-culture systems, and 3D organoid models) to measure cellular responses in inflammatory pathways, and neuronal cell signaling. Strong technical proficiency in a wide range of in vitro pharmacology techniques and assay formats, including complex cell-based phenotypic assays, immune cell-based assays, co-culture systems, inflammation-based assays, neuronal models and GI organoid systems, flow cytometry, and high content imaging.
Takeda
Boston, MA
Significant experience with drug discovery applications of cell culture including immortalized cell lines, primary cell cultures, and multicellular or organoid culture models, preferably models that recapitulate cellular cross-talk in fibroinflammatory or diseased tissues. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.
Takeda
Boston, MA
You will establish novel bioinformatics and machine learning workflows to analyze next-generation sequencing data to advance antibody sequences from in vitro (yeast and phage), in vivo (single/bulk B cells) or de novo (AI based) platforms with the goal to deeply interrogate repertoires, expand functional and sequence diversity and accelerate lead discovery using in silico tools. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.