Senior Clinical Scientist (Cambridge, MA) PhilipsSenior Clinical Scientist (Cambridge, MA)Cambridge, MAPartner with cross-functional teams including R&D, Product Management, Systems Engineering, Regulatory Affairs, Quality, and Usability to ensure clinical workflow requirements, procedural considerations, and physician feedback are incorporated into product design and validation activities. Lead and support clinical collaborations with Key Opinion Leaders, research institutions, and healthcare partners, helping to design and execute studies, including usability, phantom, animal, clinical and other evidence-generation activities.
Clinical Scientist TScan Therapeutics IncClinical ScientistWaltham, MA$145,000–$155,000 / yearThe Clinical Scientist will be responsible for leading ongoing clinical data review activities, developing data review strategies, identifying and resolving data issues, and ensuring high-quality clinical datasets are available to support safety reviews, regulatory submissions, and clinical decision-making. Position Summary: TScan is seeking a highly motivated and detail-oriented Clinical Scientist with deep expertise in clinical data management and data review to support the execution of our oncology cell therapy clinical programs.
Clinical Scientist, Associate Director Candel Therapeutics IncClinical Scientist, Associate DirectorNeedham, MA$181,000–$194,000 / yearCandel Therapeutics is seeking an experienced and intellectually curious Clinical Scientist to support our oncology clinical development programs, with an initial focus on prostate cancer and opportunities to contribute across additional solid tumor programs, including lung and brain cancer studies. Author and contribute to key clinical and regulatory documents including Clinical Study Reports (CSRs), Investigator Brochures (IBs), protocols, informed consent forms (ICFs), DSURs, clinical narratives, and IND/BLA regulatory submissions.
NewDirector, Clinical Scientist Verastem IncDirector, Clinical ScientistNeedham, MA$200,000–$260,000 / yearSupports scientific communication through literature review and development/review of abstracts, presentations, and manuscripts; maintains current knowledge of oncology, clinical development, and the external regulatory/scientific environment, and develops strong collaborative relationships across Verastem and with external scientific partners. Authors and leads key study and clinical/regulatory documents, including protocols and synopses, informed consent forms, investigator brochures, briefing books, safety updates, clinical study reports, and clinical sections of regulatory submissions and responses.
NewData Scientist Mass General BrighamData ScientistBoston, MassachusettsThe framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. They will work towards developing solutions for the entire problem-solving cycle: find/prioritize the problems, research the best algorithms to solve the problems, design robust, practical solvers, and implement them.
Clinical Scientist, Neuroimmunology & Specialty Care, PDT Takeda Pharmaceutical Co LtdClinical Scientist, Neuroimmunology & Specialty Care, PDTBoston, MA$116,000–$182,270 / yearThis role will work within the Neuroimmunology and Specialty Care team to support development of clinical assets across the United States, the European Union, and Japan, including protocol concept and protocol development, study start-up and execution, data cleaning, preparation of clinical study reports, and contributions to regulatory filings. Proven experience preparing clinical study protocols, Clinical Study Reports, integrated clinical statistical reports, and clinical sections for regulatory submissions across multiple regions, including Investigational New Drug and New Drug Application documentation.
Clinical Development Scientist AstraZeneca PlcClinical Development ScientistBoston, MA$203,709.60–$305,564.40 / yearAs a Clinical Development Scientist based in Boston or New Haven, you will sit at the center of a cross-functional study team, strengthening study quality, safeguarding data integrity, and ensuring inspection readiness across critical programs. Accountabilities: Protocol and Study Document Leadership: Contribute to the development of clinical study protocols, operations manuals, charters, monitoring plans, and other essential documents that enable efficient, inspection-ready execution.
Machine Learning Scientist – Clinical Prediction Iambic TherapeuticsMachine Learning Scientist – Clinical PredictionBoston, MassachusettsYou will identify, curate, and evaluate datasets that support prediction of relevant clinical endpoints (patient- and trial-level outcome modeling, safety/toxicity prediction, and PK/PD response modeling) and fine-tune Enchant to deliver critical clinical insights. This includes developing rigorous, leakage-resistant experimental frameworks, optimizing training, orchestrating runs at scale, and working with colleagues across ML and clinical functions to put these models into the hands of scientists making real therapeutic decisions.
Director (Principal Scientist), Clinical Research, Respiratory Merck & Co IncDirector (Principal Scientist), Clinical Research, RespiratoryBoston, MA$255,800–$402,700 / yearThe Clinical Director is responsible for maintaining a strong scientific fund of knowledge by: Maintaining awareness of scientific developments within his/her area of expertise, in terms of new scientific findings, research methodologies. The Clinical Director (Principal Scientist) has primary responsibility for planning and directing clinical research activities involving new or marketed medicines in the Cardiovascular and Respiratory therapeutic area.
Prin. Scientist, Clinical Research Merck & Co IncPrin. Scientist, Clinical ResearchBoston, MA$190,800–$300,300 / yearInterface broadly with key functions including Discovery Sciences, Preclinical Pharmacology, Pharmaceutical Sciences, Toxicology, Translational Biomarkers, Translational Medicine Operations, Translational Medicine-EU, Drug Metabolism/Modeling & Simulation, Regulatory Affairs, and late-stage Clinical Research throughout research sites around the world. Contributing to the identification of novel targets by partnering with discovery research teams to bring a clinical perspective into the earliest stages of target identification and validation, and executing clinical studies to evaluate the relevance of potential targets to human disease in order to justify investment in clinical development programs.
Assoc Dir/Director Clinical Scientist Kura OncologyAssoc Dir/Director Clinical ScientistBoston, MA$226,000–$264,000 / yearKura developed and is commercializing KOMZIFTI® (ziftomenib), the FDA-approved once-daily, oral menin inhibitor for the treatment of adults with relapsed or refractory NPM1-mutated acute myeloid leukemia, and continues to pioneer advancements in menin inhibition and farnesyl transferase inhibition. Broad understanding of functional areas of drug development, including preclinical, regulatory, pharmacovigilance, drug supply, data sciences (data management, biostatistics, programming), and clinical operations (including site selection, study start-up, study conduct, and finalization).
Sr. Scientist/Principal Scientist, Translational Research and Clinical Biomarkers (Immunology) Antares TherapeuticsSr. Scientist/Principal Scientist, Translational Research and Clinical Biomarkers (Immunology)Boston, Massachusetts$160,000–$235,000 / yearCollaborate with teams across the organization, including clinical operations and data management, to ensure biomarker assay implementation and execution, and aid in the management of biomarker samples and data. The actual salary offered will be based on a number of factors, including but not limited to the qualifications of the applicant, years of relevant experience, level of education attained, certifications or other professional licenses held, and if applicable, the location in which the applicant lives and/or from which they will be performing the job.
Staff Data Scientist, Clinical Performance Latitude Health IncStaff Data Scientist, Clinical PerformanceBoston, MA$160,000–$200,000 / yearWhile your primary focus is evaluative, you will be a key player in the broader clinical DS ecosystem, collaborating on patient risk stratification and building the forecasting engines that predict our quality performance across various value-based care programs. Automate Model Lifecycles with AI Agents: Architect and oversee AI-driven agents that autonomously manage the end-to-end lifecycle of our statistical models - leveraging automation for continuous training, deployment, performance monitoring, and proactive model refreshes.
Scientist, Quantitative Clinical Pharmacology (PK/PD Modeling & Simulation) Hemab ApSScientist, Quantitative Clinical Pharmacology (PK/PD Modeling & Simulation)Cambridge, MAYou will work closely with internal cross-functional leads (clinical pharmacology, nonclinical, clinical development, biometrics, regulatory and quality) and external collaborators (CROs and consultants) to provide quantitative insights that inform dose selection, clinical study design, and regulatory filings. As a Scientist, PK/PD Modeling & Simulation, you will be responsible for developing, validating, and applying population PK, PK/PD, exposure-response and QSP models to support model-informed drug development across Hemab's pipeline.
Assoc Dir/Director Clinical Scientist Kura Oncology IncAssoc Dir/Director Clinical ScientistBoston, MA$226,000–$264,000 / yearKura developed and is commercializing KOMZIFTI (ziftomenib), the FDA-approved once-daily, oral menin inhibitor for the treatment of adults with relapsed or refractory NPM1-mutated acute myeloid leukemia, and continues to pioneer advancements in menin inhibition and farnesyl transferase inhibition. Broad understanding of functional areas of drug development, including preclinical, regulatory, pharmacovigilance, drug supply, data sciences (data management, biostatistics, programming), and clinical operations (including site selection, study start-up, study conduct, and finalization).
Medical Laboratory Scientist I - Clinical Immunology Mass General BrighamMedical Laboratory Scientist I - Clinical ImmunologyBoston, MassachusettsAs outlined by CLIA, after successful completion of orientation, training and competency assessment on all instruments/methods applicable to their role: -Follow the laboratory's procedures for specimen handling and processing, test analyses, reporting and maintaining records of patient test results. -Be capable of identifying problems that may adversely affect test performance or reporting of test results and either must correct the problems or immediately notify the general supervisor, technical consultant, technical supervisor, clinical consultant or director; and.
Scientist, Pre-Clinical Biomarkers And Translational Research Keros TherapeuticsScientist, Pre-Clinical Biomarkers And Translational ResearchLexington, MA$133,000–$157,000 / yearYou will partner closely with Biology, Toxicology, and other cross-functional teams to translate biological questions into biomarker strategies; design and execute hypothesis-driven studies; develop fit-for-purpose assays; analyze preclinical samples; and interpret results in the context of TGF-beta superfamily biology, mechanism of action, PK/PD, efficacy, and safety. With a focus on developing differentiated product candidates that are designed to alter TGF- signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue.
Scientist, Pre-Clinical Biomarkers and Translational Research Keros TherapeuticsScientist, Pre-Clinical Biomarkers and Translational ResearchLexington, MA$133,000–$157,000 / yearYou will partner closely with Biology, Toxicology, and other cross-functional teams to translate biological questions into biomarker strategies; design and execute hypothesis-driven studies; develop fit-for-purpose assays; analyze preclinical samples; and interpret results in the context of TGF-beta superfamily biology, mechanism of action, PK/PD, efficacy, and safety. With a focus on developing differentiated product candidates that are designed to alter TGF- signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue.
NewSenior Director, Clinical Translational Scientist Kiniksa Pharmaceuticals CorpSenior Director, Clinical Translational ScientistLexington, MA$279,450–$302,220 / yearKiniksa is seeking an accomplished and strategic Senior Director, Clinical Translational Scientist reporting to GVP, Research & Non-Clinical Development to play a critical leadership role in advancing clinical-stage development programs from early clinical development through proof-of-concept and registrational studies. This individual will serve as a key scientific leader across multidisciplinary teams, integrating insights from Research, Clinical Development, Clinical Pharmacology, Bioanalysis, Biostatistics, Regulatory Affairs, and Medical Affairs to maximize the probability of technical and regulatory success across the portfolio.
Clinical Program Scientist Integrated Resources, IncClinical Program ScientistLexington, MassachusettsContractorLeads cross functional teams and is responsible for the oversight and management of study timelines as well as the financial management of a study. Ability to manage and communicate effectively with research vendors including reviewing requests for proposals, analyzing scope of work, and responding to inquiries and complaints.