Certifications: ACLS, BLS, ENPC or PALS, TNCC; Education: RN license; Location Requirements: Candidates must hold a valid RN license; Experience Requirements: Minimum of 2 years of ER experience; no minimum experience requirement is listed. Emergency Room (ER) Nurse in an acute care facility is responsible for providing critical care to patients with traumas, strokes, sepsis, congestive heart failure, and cardiac conditions.