1,474 Results for

Scientist Jobs in Littleton, MA

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Project Geologist/Environmental Scientist Mabbett & Associates, Inc.

Stoneham, MA

$80,000–$95,000 / year
Full time

This position will implement projects ranging from initial Phase I environmental site assessments through remedial investigations, feasibility studies, remediation system design, installation, system operation, and long-term maintenance and monitoring. Mabbett & Associates, Inc. (Mabbett®), an award-winning and leading environmental, health and safety consulting, and engineering firm servicing federal, state and local agencies, and private commercial, institutional and industrial clients nationally.

30+ days ago

Scientist - II (Associate) Genesis10

Cambridge, MA

Temporary
Contractor
Full time
Quick Apply

A minimum of 5 years of industry experience in in vitro biochemical and cell-based assay development and execution, including compound handling and screening workflows. Perform highly complex in vitro assays to evaluate endothelial biology, including barrier function, transport, angiogenesis, differentiation, and specialization.

2 days ago

Senior Associate Scientist Joulé

Cambridge, MA

Quick Apply

This role will contribute to therapeutic antibody discovery campaigns using rodent immunization, serum titer screening, B cell sorting by flow cytometry, immune library generation, and hybridoma-based methods. Execute established workflows to support rodent immunization studies, serum titer screening, B cell sorting, molecular cloning, and related sample processing activities.

30+ days ago

Purification & Analytics Scientist System One

Cambridge, MA

Quick Apply

Manage purification unit operations: tangential flow filtration, membrane or chromatographic purification, including double-stranded RNA removal below 1% w/w and residual DNA below 10 ng/mg. You'll provide specialist leadership on RNA purification and on the analytical strategy that determines whether a batch can be released.

13 days ago

Scientist 1 - Gas Chromatography Pace Analytical Services

Westborough, MA

Ability to work effectively in a laboratory environment, including standing for extended periods, working around strong odors, and wearing required PPE (lab coat, safety glasses, gloves—all provided by Pace®). See Pace Analytical Privacy Policy at https://www.pacelabs.com/privacy-policy/ and SonicJobs Privacy Policy at https://www.sonicjobs.com/us/privacy-policy and Terms of Use at https://www.sonicjobs.com/us/terms-conditions.

30+ days ago

Scientist/Sr. Scientist Yeast Surface Dislay Zealand Pharma A/S

Cambridge, MA

$125,000–$170,000 / year

We offer exciting responsibilities: Execute the full yeast surface display workflow, from library construction and transformation through magnetic bead and FACS-based selections, generating antibody, VHH, affibody, constrained peptide, and other mini-protein binders. As a Scientist or Senior Scientist in Yeast Surface Display, you will play a central scientific role in our new Molecular Platform Development organization, driving antibody, VHH, and other mini-protein and binder discovery through yeast display technology.

30+ days ago

Scientist/Sr. Scientist, Protein Purification Zealand Pharma A/S

Cambridge, MA

$125,000–$170,000 / year

Working knowledge of analytical characterization techniques, including mass spectrometry, biophysical methods (e.g., DLS, MALS, SPR, BLI, DSF), and flow cytometry, sufficient to collaborate effectively with analytical specialists. As a Scientist or Senior Scientist in Protein Purification and Analysis, you will play an important scientific role supporting discovery programs, with a primary emphasis on high-quality purification of protein-based therapeutics and their bioconjugates.

30+ days ago

Scientist/Sr. Scientist, Mrna Display Zealand Pharma A/S

Cambridge, MA

$125,000–$170,000 / year

Experience building custom cell-free display systems from scratch strongly preferred; experience with other in vitro display technologies (e.g., ribosome display) and cell-free protein/peptide expression systems (e.g., IVTT, CFS) is a plus. Combining more than 25 years of peptide R&D expertise with a proprietary data platform that leverages advanced data-driven and AI/ML approaches, Zealand Pharma aims to lead a new era in obesity and metabolic health.

30+ days ago

Scientist II/Senior Scientist, Solid-State Materials Lila Sciences

Cambridge, Massachusetts

$126,000–$198,000 / year

Design and execute synthesis campaigns across multiple chemical systems and structure families, drawing on the breadth of solid-state preparative chemistry (melt routes, flux, vapor transport, soft-chemical, topochemical, single-crystal growth, and unconventional or high-pressure environments as the target phase demands). Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.

22 days ago

Principal Scientist I - Molecular Histology Scientist Novartis AG

Cambridge, MA

$114,100–$211,900 / year

Key ResponsibilitiesMolecular Localization and Assay DevelopmentDevelop, optimize, validate, and implement tissue-based assays, including immunohistochemistry (IHC), multiplex immunofluorescence, and in situ hybridization (ISH/RNAscope).Serve as a molecular histology subject matter expert by evaluating antibodies, probes, controls, and assay strategies to generate robust, reproducible, and scientifically meaningful data. Extensive hands-on experience with molecular localization techniques including:Immunohistochemistry (IHC)Multiplex IHC/ImmunofluorescenceIn Situ Hybridization (ISH)RNAscope and related RNA detection technologiesProven expertise in development, optimization, validation, and troubleshooting of tissue-based assays.

5 days ago

Principal Scientist, Biomarker Assay Development Bench Scientist Novartis AG

Cambridge, MA

$108,500–$201,500 / year

Novartis Biomedical Research is seeking a highly skilled and motivated Principal Scientist (Level 4) to conduct bench research in a laboratory focused on preclinical and clinical biomarker assay development within Disease Area X (DAx). This position is integral to designing, developing, and qualifying biomarker assays that support drug discovery and development programs across DAx's diverse portfolio, including renal, liver, fibrosis, and exploratory indications.

30+ days ago

Associate Scientist / Scientist I, Computational Test Development Precede Biosciences, Inc.

Boston, MA

$110,000–$150,000 / year

We are pioneering an advanced, minimally invasive, comprehensive epigenomics platform with the potential to profoundly impact the research and development of new medicines and the use of approved medicines in clinical practice across a number of conditions, including cancer. MSc in computational biology, bioinformatics, biostatistics, or a closely related quantitative field with 3-4 years of industry or post-graduate research experience in a data-intensive biological or biomedical setting, Ph.

30+ days ago

Sr. Scientist/Principal Scientist, Translational Research and Clinical Biomarkers (Immunology) Antares Therapeutics

Boston, Massachusetts

Collaborate with teams across the organization, including clinical operations and data management, to ensure biomarker assay implementation and execution, and aid in the management of biomarker samples and data. The actual salary offered will be based on a number of factors, including but not limited to the qualifications of the applicant, years of relevant experience, level of education attained, certifications or other professional licenses held, and if applicable, the location in which the applicant lives and/or from which they will be performing the job.

30+ days ago

Scientist II or Senior Scientist, Protein Analytics Alloy Therapeutics Inc

Waltham, MA

$130,000–$160,000 / year

Alloy's Protein Analytics group, within the Alloy Antibody Powered Division, provides analytical support across all analytical activities, including assay development, quality control, high-throughput screening, and detailed characterization of monoclonal and multispecific antibodies, TCRs, TCR mimics, and other modalities. Deliver: Drive later-stage characterization efforts end-to-end, from experimental design through data interpretation, delivering robust stability and developability packages that inform key program decisions.

30+ days ago

Scientist II/Senior Scientist, Computational Biophysics Lila Sciences Inc

Cambridge, MA

$140,800–$217,800 / year

This role is one part of a broader agentic drug discovery system: computational chemistry helps judge whether agent-generated optimization strategies are chemically sensible, ML scientists build cofolding and low-data learning models, and research engineers help turn validated scientific protocols into reliable scalable infrastructure. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.

30+ days ago

Associate Scientist / Scientist I, Computational Test Development Precede Biosciences Inc

Boston, MA

$110,000–$150,000 / year

30+ days ago

Scientist/Senior Scientist, Assay Development - Neuroscience Biomarkers Spear Bio Inc

Woburn, MA

Provide scientific leadership and translate biomarker biology into assay-design strategies by optimizing for clinically relevant molecular forms, isoforms, post-translational modifications, cleavage fragments, aggregation states, epitopes, and sample types. The successful candidate will help optimize assay strategies, identify the most relevant molecular forms and epitopes, evaluate preanalytical variables and matrix effects, interpret clinical-sample data, and troubleshoot complex assay-development challenges.

30+ days ago

Scientist II/Senior Scientist, Solid-State Materials Lila Sciences Inc

Cambridge, MA

$126,000–$198,000 / year

23 days ago

Associate Scientist/Senior Associate Scientist, In Vivo Pharmacology - Study Coordinator Manifold Bio

Boston, MA

$106,000–$123,000 / year

Work closely with pharmacology team members to oversee and execute assays assessing the pharmacological activity, biodistribution, and efficacy of test articles in research and preclinical studies, supporting development of therapies across the pipeline. This is a senior, hands-on role at the intersection of scientific rigor and operational excellence - you will be the single point of accountability for study lifecycle management across multiple parallel programs, from initial study design through execution, collection, and delivery.

30+ days ago

LC-MS Associate Scientist/Senior Scientist Novabioassays

Woburn, Massachusetts

Prefer to have hands-on experience on following instrument and software: Sciex Triple Quadruple Mass Spec with Analyst software, Thermo Orbitrap Mass Spec with Xcalibur software, Thermo Watson LIMS software, Ligand-Binding assays, Hybridization LC-Fluorescence assays, RT-qPCR . These are Associate Scientist and Senior Scientist roles in the Bioanalytical Group to help developing, qualifying/validating bioanalytical methods, and analyzing small and large molecule in different biological matrix.

30+ days ago

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Scientist Jobs in Littleton, MA

Project Geologist/Environmental Scientist Mabbett & Associates, Inc.

Scientist - II (Associate) Genesis10

Senior Associate Scientist Joulé

Purification & Analytics Scientist System One

Scientist 1 - Gas Chromatography Pace Analytical Services

Scientist/Sr. Scientist Yeast Surface Dislay Zealand Pharma A/S

Scientist/Sr. Scientist, Protein Purification Zealand Pharma A/S

Scientist/Sr. Scientist, Mrna Display Zealand Pharma A/S

Scientist II/Senior Scientist, Solid-State Materials Lila Sciences

Principal Scientist I - Molecular Histology Scientist Novartis AG

Principal Scientist, Biomarker Assay Development Bench Scientist Novartis AG

Associate Scientist / Scientist I, Computational Test Development Precede Biosciences, Inc.

Sr. Scientist/Principal Scientist, Translational Research and Clinical Biomarkers (Immunology) Antares Therapeutics

Scientist II or Senior Scientist, Protein Analytics Alloy Therapeutics Inc

Scientist II/Senior Scientist, Computational Biophysics Lila Sciences Inc

Associate Scientist / Scientist I, Computational Test Development Precede Biosciences Inc

Scientist/Senior Scientist, Assay Development - Neuroscience Biomarkers Spear Bio Inc

Scientist II/Senior Scientist, Solid-State Materials Lila Sciences Inc

Associate Scientist/Senior Associate Scientist, In Vivo Pharmacology - Study Coordinator Manifold Bio

LC-MS Associate Scientist/Senior Scientist Novabioassays

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