Senior AI Devops Engineer Vertex Pharmaceuticals, IncSenior AI Devops EngineerBoston, MA$112,000–$168,000 / yearWorking closely with software engineers, cloud architects, information security teams, and business stakeholders, this individual will drive the adoption of DevSecOps best practices, cloud automation, infrastructure as code, and secure software delivery pipelines. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Senior Director, Core Technology Architect Vertex PharmaceuticalsSenior Director, Core Technology ArchitectBoston, Massachusetts$228,000–$342,000 / yearPartner with Information Security to co-architect and integrate cybersecurity platforms and controls across cloud, network, workplace, collaboration, and end-user computing domains, ensuring alignment with Core Technology reference architecture, operational models, and enterprise risk requirements. Vertex is seeking a Senior Director, Solution Architect – Core Technology to serve as a senior individual contributor responsible for defining and driving an integrated architecture strategy across infrastructure and collaboration platforms in a global, GxP-regulated biopharma environment.
Senior Principal, Source To Pay Technology Vertex Pharmaceuticals, IncSenior Principal, Source To Pay TechnologyBoston, MA$177,600–$266,400 / yearThis role will partner with business leadership to identify and prioritize opportunities to improve business processes with innovative technology and data, gathering and refining requirements, determining options for solution design, delivering enhancements, supporting integrations, and contributing to technology projects and initiatives. Knowledge and Skills: Experience with Source to Pay technologies (e.g., Contract Lifecycle Management platform (Icertis), Third-Party Risk Management platform (ProcessUnity), Electronic Signature platform (Docusign), Procure-to-Pay platform (Coupa), and Source to Pay Orchestration tools).
Patient Safety Senior Medical Director Vertex PharmaceuticalsPatient Safety Senior Medical DirectorBoston, Massachusetts$276,000–$414,000 / yearThis role will lead Risk Management activities, pre-, peri- and post-approval (as applicable) for assigned compound(s) and will provide relatively autonomous leadership of periodic (aggregate) safety report, signaling, labelling and DST activities for assigned compounds, as well as participate in individual case medical review. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Sourcing Contracts Senior Manager Vertex PharmaceuticalsSourcing Contracts Senior ManagerBoston, Massachusetts$132,000–$198,000 / yearAble to independently establish and maintain effective business partner relationships with stakeholders; consistently gains stakeholder respect and trust; Strong communication skills, written and verbal; able to clearly articulate opinions in concise and persuasive manner. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Senior Data Platform Engineer VIASenior Data Platform EngineerSomerville, MassachusettsRemote$145,000–$190,000 / yearEngineer and deploy data pipelines: Develop, deploy, and maintain resilient pipelines for both real-time streaming and batch processing, with deployment (CI/CD, IaC) as a top priority, ensuring seamless data flow from raw ingestion to production-ready applications. As a Senior Data Platform Engineer at VIA, you'll bring together core data engineering skills with an interest in the DevOps side of things: Kubernetes, container insights, and resource allocation, alongside a solid understanding of our application logic, database queries, and data pipeline orchestration.
Senior Principal AI Platform Engineer, Data & AI Platform Vertex PharmaceuticalsSenior Principal AI Platform Engineer, Data & AI PlatformBoston, Massachusetts$188,000–$282,000 / yearWe seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. Team Enablement – Act as a technical multiplier by providing reusable architecture patterns, starter kits, and developer-first abstractions to empower teams across Vertex to build and deploy AI solutions effectively.
Analytics CoE Senior Manager Vertex PharmaceuticalsAnalytics CoE Senior ManagerBoston, MassachusettsRemote$144,000–$216,000 / yearWe seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. The Senior Manager Director role is within HEOR’s Analytics Center of Excellence (CoE), a specialized team that provides strategic and technical support to HEOR, Market Access & Pricing, and the broader commercial organization.
Senior Principal Scientist, Applied AI & Agentic Systems For Small-Molecule Drug Discovery Vertex Pharmaceuticals, IncSenior Principal Scientist, Applied AI & Agentic Systems For Small-Molecule Drug DiscoveryBoston, MA$168,000–$252,000 / yearWorking at the intersection of Computational Drug Design, project teams, Data & Methods, and Digital Technology & Engineering, this individual will leverage deep expertise in computational chemistry, cheminformatics, and AI-driven drug discovery to identify high-value opportunities across the design-make-test-analyze (DMTA) cycle and translate them into scientifically rigorous AI co-scientists that enhance compound design, knowledge synthesis, data interpretation, hypothesis generation, and decision-making. Partner with project teams and scientific leaders to develop and deploy AI co-scientists that support knowledge synthesis, SAR analysis, scientific question answering, experiment planning, virtual screening, molecular design, and lead optimization, leveraging established computational chemistry and cheminformatics approaches alongside modern AI methods.
Senior Director Cell & Genetic Therapies Quality - Personalized Medicine Vertex PharmaceuticalsSenior Director Cell & Genetic Therapies Quality - Personalized MedicineBoston, Massachusetts$213,600–$320,400 / yearEstablish compliance governance routines to proactively monitor compliance trends, operational performance, and emerging risks that may impact product quality, patient safety, supply continuity, or program execution; lead or support risk-based mitigation plans, continuous improvement actions, and sustainable process enhancements. Provide strategic Quality Systems leadership in support of personalized medicine /advanced CGT programs, ensuring alignment with CGT Business Objectives, Vertex Global Quality Strategy, commercial priorities, regulatory expectations, and patient-centered outcomes.
Senior Director, Analytical Development, Testing and Lab Automation Vertex PharmaceuticalsSenior Director, Analytical Development, Testing and Lab AutomationBoston, Massachusetts$226,100–$339,100 / yearThe Senior Director, Analytical Development is a senior leadership role within the Cell and Gene Therapy Analytical Development function and will be responsible for setting and driving the company’s analytical testing strategy, including manual and automated testing approaches, analytical operations, and implementation of automation capabilities. The role will work closely with Manufacturing, Process Development, Regulatory, Quality, CMC, and external partners to generate high-quality data that informs strategy and decisions, while advancing next-generation analytical automation tools for characterization of cell, gene and biologic therapy processes and products.
Senior Consultant (Commercial Due Diligence) Stax LLCSenior Consultant (Commercial Due Diligence)Boston, MA$165,000–$190,000 / yearAs a Commercial Due Diligence Senior Consultant, you'll focus on buy‑side and sell‑side transaction engagements, supporting corporate clients and private equity investors as they evaluate growth opportunities, revenue sustainability, and market risk. Help build a rapidly growing platform post-acquisition, with opportunities to shape capabilities, develop new offerings, and contribute to firm-wide growth initiatives.
Senior Hydrogeologist 2 Haley & Aldrich IncSenior Hydrogeologist 2Boston, MA$105,000–$130,000 / yearExperience applying geotechnical principles and integrating geotechnical and hydrogeologic data in multidisciplinary evaluations such as basal stability, seepage analyses, permanent pressure relief, construction dewatering, and drawdown induced settlement. The successful candidate will integrate hydrogeologic and geotechnical data to develop conceptual site models, evaluate groundwater flow, construction dewatering, seepage, and slope-stability conditions, and support multidisciplinary project teams.
Sr Project Controls Professional Data Center Jacobs Solutions IncSr Project Controls Professional Data CenterBoston, MA$123,600–$220,000 / yearWe are seeking an experienced Sr Project Controls Professional to support an ongoing site-based assignment in Spartanburg, SC, with future projects also requiring on-site presence across the U.S. This senior-level role is ideal for a detail-oriented and collaborative professional with a strong background in cost control and construction progress tracking. At Jacobs, we're challenging today to reinvent tomorrow by solving the world's most critical problems for thriving cities, resilient environments, mission-critical outcomes, operational advancement, scientific discovery and cutting-edge manufacturing, turning abstract ideas into realities that transform the world for good.
Senior Vice President, Clinical Development (FcRn/Immunology) Viridian Therapeutics IncSenior Vice President, Clinical Development (FcRn/Immunology)Waltham, MAThis leader will provide medical and scientific leadership by leading the clinical development team and trial activities across development planning: study design, protocol execution, data interpretation, regulatory strategy, and external scientific engagement in investigator meetings and key external medical relationships. Collaborate closely with functional leaders in Program Leadership, Clinical Operations, Data Management, Global Safety/ Pharmacovigilance, Biometric Sciences and Regulatory Affairs to support clinical and program teams in the design, planning, execution and reporting of clinical plans and studies.
Senior Security Engineer, Corporate Services Security Amazon.com IncSenior Security Engineer, Corporate Services SecurityBoston, MAThis role requires deep technical expertise and leadership in application security, threat modeling, and secure system design, combined with the ability to influence engineering teams and deliver high-impact security outcomes with minimal guidance. The Corporate Services Security (CPSS) Finance and Communication Security (FCS) Team is responsible for securing the applications, infrastructure and data developed across Finance & Global Business Services (FGBS) and Communications and Corporate Responsibility (CCR).
Senior Solutions Architect, AGS Software and Technology (SWAT) Amazon.com IncSenior Solutions Architect, AGS Software and Technology (SWAT)Boston, MAWe pioneered cloud computing and never stopped innovating - that's why customers from the most successful startups to Global 500 companies trust our robust suite of products and services to power their businesses. Educate SWAT customers on the value proposition of AWS, and participate in deep architectural discussions to ensure solutions are designed for successful deployment in the cloud.
Senior Overhead Transmission Line Engineer Jacobs Solutions IncSenior Overhead Transmission Line EngineerBoston, MA$138,400–$240,000 / yearAt Jacobs, we're challenging today to reinvent tomorrow by solving the world's most critical problems for thriving cities, resilient environments, mission-critical outcomes, operational advancement, scientific discovery and cutting-edge manufacturing, turning abstract ideas into realities that transform the world for good. In response, Jacobs is expanding its Transmission & Distribution (T&D) operations In North America and is looking for a Senior Overhead Transmission Line Engineer in its Energy & Power Group to tackle the complexities of decarbonization and utility modernization to deliver a cleaner and more secure energy future.
Senior Wealth Client Specialist First Citizens BancShares IncSenior Wealth Client SpecialistBoston, MA$38–$46 / hourFrom life's biggest financial decisions to everyday needs big and small, our First Citizens Wealth team delivers banking, investment, insurance, and many more solutions that support the moments that matter most. The Senior WCS also assists with office related support such as coordinating and preparing for client meetings, mail handling and distributions as well as assisting with ordering office supplies when needed.
Senior Director, Clinical Research - Neurodegeneration Alnylam Pharmaceuticals IncSenior Director, Clinical Research - NeurodegenerationCambridge, MA$305,700–$413,700 / yearThis is an opportunity to provide clinical leadership in developing RNAi therapeutics in Alnylam's rapidly expanding portfolio, which spans the areas of rare genetic diseases, cardio-metabolic diseases, neuroscience, hematology and hepatology. The Senior Director, Clinical Research, will work in a matrix organization across Regulatory, Biostatistics, Clinical Operations, Preclinical, Commercial & QA teams to ensure fully harmonized and integrated development strategies.