Principal Scientist, Protein Design ModernaTXPrincipal Scientist, Protein DesignCambridge, MassachusettsThis role will lead the design, execution, and continuous advancement of high-throughput mammalian cell–based screening platforms that interrogate broadly applicable design principles for glycoprotein antigens, enabling antigen optimization, improved expression and durability across multiple programs, and rapid maturation of computationally designed candidates. The candidate in this position will work closely with and report to the Senior Director, Computational Design and In Vitro Selection, and will also work closely with the VP, Protein Design, as well as other members of Research, to advance novel candidates to the clinic, drive exploratory trials to inform the generation of improved vaccine antigens and explore new concepts for mRNA medicines.
Senior Bioinformatics Engineer Moderna IncSenior Bioinformatics EngineerCambridge, MA$145,900–$234,200 / yearWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. You will play a key role in maintaining continuous software operations, supporting validation activities, enhancing automation capabilities, and collaborating with multidisciplinary teams to strengthen the robustness of scientific software platforms.
NewSenior Director, AIRx Medicinal Chemistry Takeda PharmaceuticalSenior Director, AIRx Medicinal ChemistryBoston, MA$212,000–$333,190 / yearSee Takeda Pharmaceutical Terms of Use at https://www.takeda.com/terms-of-use/ and Privacy Policy at https://www.takeda.com/privacy-notice/ and SonicJobs Privacy Policy at https://www.sonicjobs.com/us/privacy-policy and Terms of Use at https://www.sonicjobs.com/us/terms-conditions. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.
Bioinformatician - Computational Biology & AI Omics ZifoBioinformatician - Computational Biology & AI OmicsBoston, MAApply molecular techniques, bioinformatics pipelines, relational data systems, and statistical analysis to generate biological insights using internal and external data sets, published literature, and other resources to accelerate biomarker discoveries. You will be responsible for deploying solutions that play a critical role in the early-stage optimization and development of assays by supporting analysis and interpretation of data for large biotech/pharma and other ‘Omics focused companies.
Post-Doctoral Research Fellow – Functional Genomics Massachusetts General Physicians OrganizationPost-Doctoral Research Fellow – Functional GenomicsBoston, Massachusetts$70,000–$71,750 / yearCandidates will work with cutting-edge data types like single-cell transcriptome sequencing, Hi-C studies of 3D topology, ATACseq, 4Cseq, and other datasets in iPSC-derived neurons and organoid models of neurodevelopment. The Talkowski Laboratory in the Center for Genomic Medicine (CGM) at Massachusetts General Hospital (MGH), Harvard Medical School, and the Broad Institute is seeking exceptional postdoctoral candidates in computational biology, bioinformatics, and/or statistical genetics.
Computational Biologist - Spatial Multi-Omics Bayer AGComputational Biologist - Spatial Multi-OmicsCambridge, MA$106,400–$159,600 / yearThe primary responsibilities of the Director, Computational Biologist - Spatial Multi-Omics are to: Build and maintain scalable pipelines for spatial and deep visual multi-omics analysis, including data ingestion, QC, normalization, batch correction, feature extraction, and annotation from mass-spectrometry and transcriptomics platforms. Bayer seeks an incumbent who possesses the following: Required qualifications: PhD in Computational Biology, Bioinformatics, Systems Biology, Biostatistics, Computer Science, or related field; or MSc with substantial relevant experience.
Post Doc - Open Rank University of Massachusetts Medical SchoolPost Doc - Open RankWorcester, MassachusettsOur laboratory combines human pluripotent stem cell differentiation, CRISPR-based (epi-)genome engineering, single-cell multi-omics, immunology, and computational biology to identify mechanisms that protect stem cell–derived islets from autoimmune and allogeneic immune responses while preserving beta-cell identity and function. The successful candidate will lead efforts using CRISPR genome engineering and functional genomics screens to identify regulatory programs and its underlying factors that improve the survival, function, and immune compatibility of stem cell–derived islets.
Scientist, Bioconjugation Manifold Bio IncScientist, BioconjugationBoston, MA$118,000–$138,000 / yearYou will join a team with deep experience in protein chemistry, RNA biology, and biology, and work closely with a highly interdisciplinary team of creative experimental and computational scientists to advance our tissue-targeted oligomedicines pipeline. Manifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively multiplexed in vivo screening to unlock tissue-targeted medicines and organism-scale models of living systems.
Data Foundations Lead UCB SAData Foundations LeadBoston, MA$148,000–$194,300 / yearFor this role we're looking for the following education, experience and skills: Education: Bachelor's or Master's degree in Computer Science, Data Science, Information Management, Bioinformatics or a related discipline. Working across scientific, digital and enterprise teams, you will help shape how data is created, governed and consumed to accelerate research, innovation and AI-driven decision making.
HMS - Associate in Biomedical Informatics (Baym Lab) Harvard UniversityHMS - Associate in Biomedical Informatics (Baym Lab)Cambridge, MAThe candidate will work with a multi-disciplinary team of computational biologists, evolutionary biologists, and microbiologists to conduct research on mobile genetic element genetics and biology using a mixture of synthetic, genetic, and computational tools. The Department of Biomedical Informatics (DBMI) at Harvard Medical School and the Baym Lab are seeking an Associate, postbacalaureate researcher, with experience in the evolution of mobile genetic elements.
NewDirector, Biotherapeutic Production Technologies Generate BiomedicinesDirector, Biotherapeutic Production TechnologiesSomerville, MassachusettsThe successful candidate will bring broad expertise across upstream expression and downstream purification, with particular strength in stable cell line technologies, vector and construct design, multi-gene expression, and the production of diverse or complex therapeutic protein modalities. Generate:Biomedicines is seeking an experienced and innovation-minded Director, Biotherapeutic Production Technologies, to define the strategy and lead the team responsible for protein expression, purification, and fit-for-purpose characterization in support of discovery and early development.
Sr Director, Clinical Excellence Group Lead (I&I) PfizerSr Director, Clinical Excellence Group Lead (I&I)MassachusettsExperience: 10+ years with a MBA/MS or 7+ years with PhD of progressive clinical research and development experience in the pharmaceutical or biotechnology industry, including demonstrated experience supporting global clinical programs in regulated GxP environments. This leader will also help advance new ways of working, including the responsible integration of AI-enabled, digital, data, and advanced analytics capabilities to improve clinical development quality, speed, and decision-making.
Sr Computational Biologist Foundation Medicine IncSr Computational BiologistBoston, MA$145,000–$180,000 / yearThis role leverages multi-modal data, including large scale genomics, real-world clinical outcomes, and imaging datasets, to identify and establish feasibility of novel biomarkers and therapeutic targets. Utilize statistical expertise to explore multimodal data and lead scientific investigations into mechanisms of oncogenesis, prognostic and predictive biomarkers, drug resistance, and disease monitoring.
HMS - Postdoctoral Fellow in Biomedical Informatics (HIDIVE Lab) Harvard UniversityHMS - Postdoctoral Fellow in Biomedical Informatics (HIDIVE Lab)Cambridge, MAOur work also benefits from multiple research software products (e.g., HiGlass, Vitessce, Gosling, HuBMAP Data Portal User Interface, etc.) that the HIDIVE Lab has developed and maintains through a team of engineers and designers. The HIDIVE Lab has an international reputation for creating high impact data visualization tools and we are driven to solve the most challenging design and engineering problems where biomedical data, humans, and AI meet.
Principal Scientist, Oncology Informatics, AI agents Bristol-Myers Squibb CoPrincipal Scientist, Oncology Informatics, AI agentsMA$166,770–$202,086 / yearIPS conducts applied computational research in areas that include genomic, structural and molecular informatics, computational and systems biology, patient selection and translational biomarker research, and broader fields including knowledge science, epidemiology and machine learningacross the full lifecycle of drug discovery and development and across all therapeutic areas at BMS. Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
Scientist Metabolomics Alnylam Pharmaceuticals IncScientist MetabolomicsCambridge, MA$110,400–$165,600 / yearDirect experience with triple-quadrupole and high-resolution accurate mass LC-MS/MS-based methods for endogenous metabolite/lipid quantification (ideally with Sciex QTRAP and Thermo Orbitrap systems), including assay development and validation. We use untargeted and targeted liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based omics and computational biology to support biomarker discovery and target validation efforts for our RNAi-based therapeutics.
Postdoctoral Scientist - Neuropsychiatry Eli Lilly and CompanyPostdoctoral Scientist - NeuropsychiatryBoston, MA$58,000–$123,200 / yearOur current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women's Initiative for Leading at Lilly (WILL). In this role, you will: Develop and characterize human iPSC-derived tri- and quad-culture models containing excitatory neurons, inhibitory neurons, astrocytes, and potentially microglia to study neuron-glia interactions in psychiatry-relevant contexts.
Biological Structures Data Engineer I/II Iambic TherapeuticsBiological Structures Data Engineer I/IIBoston, MassachusettsWorking alongside ML scientists, you will design, implement, and harden the workflows that prepare experimental structural (e.g., protein–ligand complexes) and affinity data for training, and help create and ingest large volumes of high-quality computationally generated synthetic data. Iambic Therapeutics is seeking a Biological Structures Data Engineer to join the NeuralPLexer team and own the data pipelines for acquiring, curating, and transforming experimental and synthetic data to train the next generation of NeuralPLexer models.
Pathology Computational Scientist Brigham and Women's HospitalPathology Computational ScientistBoston, MA$93,953.60–$136,739.20 / yearApplications will include forecasting microbial population dynamics in the gut, characterizing the impact of spatial structure of the microbiome, predicting impact of the microbiome on host phenotype, tracking infections in human populations, elucidating microbial metabolism, and discovering functions of uncharacterized microbial metabolites and proteins. With recent funding from the Massachusetts Life Sciences Center, the Lab has built a state-of-the-art compute cluster with extensive GPU and CPU nodes, with the objective of making advanced deep learning technologies broadly available to microbiome researchers.
Data Scientist, AI for Biomedical Imaging Novartis AGData Scientist, AI for Biomedical ImagingCambridge, MA$126,000–$234,000 / yearWe partner closely with experimental scientists, disease-area teams, data scientists, bioinformatics experts, and platform engineers to extract meaningful biological insight across diverse imaging modalities (high-content screening, custom microscopy platforms) and biological model systems (cellular assays, co-cultures, organoids, tissue models).To grow this capability, we are seeking a seasoned, innovative, and collaborative data scientist with deep expertise in AI-enabled image analysis to join the Data Science team in Discovery Sciences (DSc) at Novartis Biomedical Research, Cambridge, MA. Demonstrated experience developing and validating image analysis algorithms for biological, biomedical, or pharmaceutical research applications, with practical experience in image segmentation, feature extraction, phenotypic profiling, object classification, or representation learning applied to high-content or high-throughput imaging data.