Design fluidic and mechanical hardware in CAD (SolidWorks, Onshape, or similar): manifolds, sensor housings, reservoirs, bubble traps, sealed enclosures, and rig-integration hardware, with attention to O-ring and gasket sealing, dead-volume minimization, tolerance stack-ups, and biocompatible, cleanable material selection. BrainEx is a proprietary closed-loop physiological system that functions as an artificial cardiovascular, pulmonary, and renal system for an intact human brain — custom hardware and software regulating circulatory volume, cerebral blood flow, systolic pressure and pulsatility, pH, dissolved gases, temperature, metabolites, and drug dosing throughout each run.