Sr. Scientific Director, Toxicology Neurocrine Biosciences Inc.Sr. Scientific Director, ToxicologySan Diego, CA$226,600–$309,000 / yearThe company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in Prader-Willi syndrome, endometriosis and uterine fibroids , as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. Oversees the safety pharmacology and toxicology studies including protocol design, advises and directs the execution, data interpretation, and review of reports for new therapeutic entities of various modalities (small molecules, large molecules, peptide conjugates, oligonucleotides, and gene therapies).
SENIOR DIRECTOR, TOXICOLOGY Scripps ResearchSENIOR DIRECTOR, TOXICOLOGYSan Diego, CA$230,000–$280,000 / yearPart timeLeveraging the unique scientific environment of Scripps Research, impacting translational sciences, Calibr-Skaggs has created a portfolio of drug candidates, and is shaping a new paradigm for advancing nonprofit biomedical research to impact patients while reinvesting in further innovative research. Calibr-Skaggs’ drug development portfolio spans a broad range of human diseases, including cancer, autoimmunity and inflammatory diseases, metabolic and cardiovascular diseases, infectious and neglected tropical diseases, as well as age-related and degenerative diseases.
Senior Scientist, Toxicology Airna Corp incSenior Scientist, ToxicologySan Diego, CAAIRNA has raised $245 million in financing from a world-class syndicate of investors including Arch Venture Partners, Forbion, Venrock Healthcare Capital Partners, RTW Investments, Nextech Invest, and ND Capital. JOB DESCRIPTION: AIRNA is seeking a highly motivated Senior Scientist in Toxicology to help drive the pre-clinical safety strategy for the successful development of oligonucleotide programs across all stages of development.
Toxicology Research Scientist Vertex PharmaceuticalsToxicology Research ScientistSan Diego, CaliforniaThe successful candidate will have a proven track record of working with complex in vitro models, including primary cells and immune cells in 3D formats or co-culture systems, and will bring expertise in developing and applying innovative approaches to assess molecular toxicities. This lab-based role offers an exciting opportunity to lead the development of advanced 3D organoid models, organ-on-a-chip technologies, and fit-for-purpose assays to investigate toxicological mechanisms and support our therapeutic discovery and development efforts.
Associate Director /Director- Scientific Operations, Specialty Toxicology RPM ReSearchAssociate Director /Director- Scientific Operations, Specialty ToxicologySan Diego, CaliforniaProvide a senior-level review of reports, protocols, and related documents for appropriate scientific content and interpretation of studies in collaboration with other senior staff. Primary responsibilities : Direct the science and operations involved in the direction, conduct, and execution of Preclinical Analytical Laboratory Sciences operations and studies.
Scientific Director, Toxicology Neurocrine Biosciences IncScientific Director, ToxicologySan Diego, CA$194,600–$265,000 / yearThe company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in Prader-Willi syndrome, endometriosis and uterine fibroids , as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. Manage and provide scientific leadership to the internal staff and work closely with Discovery, Preclinical and Clinical Pharmacology (PCCP), Clinical Development, and Regulatory to integrate nonclinical safety findings into overall program strategy and goals.
Director, Biology San Diego, CA (onsite), Confidential Search Ignite Human CapitalDirector, Biology San Diego, CA (onsite), Confidential SearchSan Diego, CAThis company was founded by the scientific and drug development team behind one of the most significant recent breakthroughs in IBD: the discovery of a novel inflammatory pathway and the antibody therapy that targets it, which advanced from academic research into late-stage clinical development and was ultimately acquired for over $10 billion. A newly established, well-funded biotechnology company in San Diego is building a precision medicine pipeline in inflammatory bowel disease (IBD) — one designed to move beyond today's empirical treatment model toward therapies that both calm inflammation and actively promote tissue healing.
Chief Scientific Officer Travere Therapeutics IncChief Scientific OfficerSan Diego, CARemote$325,000–$439,000 / yearThe CSO provides executive leadership and strategic direction for the Company's Research and Technical Operations organizations through direct leadership of the Head of Research and the Head of Technical Operations, ensuring the Company's scientific strategy is translated into research priorities, technical capabilities, and organizational excellence that support development programs, commercial products, and future pipeline assets spanning discovery through commercialization. Partner with the Head of Research to build and continuously evolve a world-class research organization by expanding capabilities across early clinical science, translational research, preclinical collaborations, assay development, nonclinical pharmacology and toxicology, biomarker sciences, medical genetics, newborn screening, and scientific collaborations in support of the Company's current and future portfolio.
Director, Biology Group Lead Bristol Myers SquibbDirector, Biology Group LeadSan Diego, CA$227,418–$275,577 / yearThe role will also provide strategic leadership in the development of quantitative pharmacology and target engagement platforms, ensuring robust biochemical and cellular characterization of drug-target interactions to support target validation, lead optimization, and candidate selection across the radiopharmaceutical portfolio. Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
VICE PRESIDENT, PRECLINICAL & CLINICAL DEVELOPMENT Scripps ResearchVICE PRESIDENT, PRECLINICAL & CLINICAL DEVELOPMENTSan Diego, CA$303,600–$322,000 / yearPart timeLeveraging the unique scientific environment of Scripps Research, impacting translational sciences, Calibr-Skaggs has created a portfolio of drug candidates, and is shaping a new paradigm for advancing nonprofit biomedical research to impact patients while reinvesting in further innovative research. Calibr-Skaggs’ drug development portfolio spans a broad range of human diseases, including cancer, autoimmunity and inflammatory diseases, metabolic and cardiovascular diseases, infectious and neglected tropical diseases, as well as age-related and degenerative diseases.
Senior Director of Drug Safety XtalPi IncSenior Director of Drug SafetySan Diego, CAWorking at the interface of computational design, translational biology and preclinical development, you will integrate mechanistic toxicology, pharmacology, DMPK and emerging clinical insights to enable informed, data-driven programme decisions and successful human translation. Reporting to the VP, Head of In Vivo Bioscience, the role will shape nonclinical and translational safety strategies supporting the progression of novel biologics, multi-specific antibodies and peptide therapeutics from discovery through early clinical development.