37 Results for

Toxicology Jobs in Massachusetts

Jobs

MA30+ days ago

$284,800–$385,200 Per Year

In addition to leading and contributing to regulatory toxicology activities, this role will place strong emphasis on supporting research initiatives and providing scientific leadership within the broader Early Development department. Overview: The successful candidate will join an experienced team of toxicologists providing discovery and development support across a strong and diverse pipeline of programs spanning multiple disease areas.

Boston, Massachusetts22 days ago

This is an individual contributor role by designing, conducting or overseeing studies, analyze/interpret, and report in vitro, ex vivo, and in vivo non-GLP (or GLP studies conducted at CROs) nonclinical pharmacology, PK/PD, and/or toxicology studies, in collaboration with study monitors and other scientists. The discovery toxicologist interacts directly with multidisciplinary teams including biology, medicinal chemistry, DMPK, clinical science, and outside CRO’s in research and/or development projects to move discovery candidates into development.

Boston, MA30+ days ago

$320,000–$350,000 Per Year

Reporting to our SVP, Nonclinical & Translational Development, the Head of Toxicology partners closely with cross‑functional teams and represents nonclinical safety in regulatory interactions while building a strong, high‑performing toxicology organization. Centessa Pharmaceuticals is seeking an Executive Director/Head of Toxicology to provide scientific and strategic leadership for nonclinical safety across discovery and development programs, with an emphasis on small‑molecule therapeutics.

Boston, MA30+ days ago

This is an individual contributor role by designing, conducting or overseeing studies, analyze/interpret, and report in vitro, ex vivo, and in vivo non-GLP (or GLP studies conducted at CROs) nonclinical pharmacology, PK/PD, and/or toxicology studies, in collaboration with study monitors and other scientists. The discovery toxicologist interacts directly with multidisciplinary teams including biology, medicinal chemistry, DMPK, clinical science, and outside CROs in research and/or development projects to move discovery candidates into development.

Cambridge, MA30+ days ago

Remote

$272,538–$333,102 Per Year

How You Will Achieve More: The Senior Director of Development Pharmacology & Toxicology provides strategic leadership in establishing and executing pharmacology and toxicology strategies across multiple therapeutic platforms, including nucleic acid, lipid nanoparticle, cell therapy, small and large molecule. Responsibilities: Establish and direct platform-wide testing strategies across therapeutic modalities, proactively anticipating evolving guidance from FDA, EMA, ICH and other agencies to create innovative approaches for gene editing, nucleic acid, lipid nanoparticle, and AAV products.

Cambridge, MA30+ days ago

$65–$90 Per Hour

In terms of professional development, Everforth Apex hosts an on-demand training program, provides access to certification prep and a library of technical and leadership courses/books/seminars once you have 6+ months of tenure, and certification discounts and other perks to associations that include CompTIA and IIBA. Our Cambridge based biotech client is looking for a highly motivated Senior Scientist in Toxicology to help shape the preclinical safety strategy for oligonucleotide programs across all stages of development.

Cambridge, MA16 days ago

$185,000–$260,000 Per Year

Beam's suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. Provide toxicology support for regulatory submissions and interactions with health authorities, including the authoring of nonclinical safety sections of US and international regulatory applications, and help resolve nonclinical safety queries.

Cambridge, Massachusetts13 days ago

PhD or DVM, or equivalent advanced degree in Toxicology, Pharmacology, Pathology, Veterinary Sciences, or a related field, with 5+ years, Masters with 7+ or a Bachelors with 10+ of relevant experience in biotech or pharmaceutical drug development, or direct experience as a Study Director at a GLP-qualified CRO. We’re seeking an Associate Director, Nonclinical Safety Evaluation (NSE) who will play a pivotal role in overseeing and critically evaluating nonclinical safety studies across City’s RNAi therapeutic programs.

Cambridge, MA30+ days ago

$185,000–$260,000 Per Year

Boston, Massachusetts9 days ago

Work within a close-knit team, this individual will leverage advanced in vitro technologies, laboratory automation, and computational approaches to design, execute, analyze, and derive insights from mechanistic and phenotypic screening assays designed to evaluate the safety of new candidate molecules. The individual will work closely with cross-functional colleagues across Preclinical Sciences, Medicinal Chemistry, Data and Computational Sciences, Data Technology and Engineering, and Research with the shared goal of advancing the Vertex portfolio.

Cambridge, MA30+ days ago

$228,000–$280,000 Per Year

Flagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company's annual list of the World's Most Innovative Companies. Harnessing the drug development expertise of its team together with the power of Flagship's multiple scientific platforms, Pioneering Medicines explores and identifies new product concepts which are then advanced jointly with Flagship's bioplatform companies.

Boston, MA16 days ago

$160,000–$220,000 Per Year

Antares Therapeutics is seeking an enthusiastic and self‑motivated Senior Scientist/Principal Scientist, Toxicology to join the Nonclinical Development group and support nonclinical safety assessment activities from discovery through IND‑enabling stages across the Antares pipeline. The successful candidate will play a key role in the design, execution, and interpretation of nonclinical safety studies, working both hands‑on in the laboratory and in close collaboration with external CROs.

Cambridge, MA30+ days ago

$175,000–$260,000 Per Year

Experience designing, outsourcing, and overseeing nonclinical toxicology studies at external CROs, including international vendors; prior experience working with CROs in China (or broader APAC region) is highly desirable. By editing RNA instead of DNA, Korro is expanding the reach of genetic medicines by delivering additional precision and tunability, which has the potential for increased specificity and improved long-term tolerability.

Waltham, MA30+ days ago

$159,000–$195,000 Per Year

Role Summary: The Principal Scientist, Toxicology is a key member of preclinical development teams and is responsible for the strategic planning and execution of nonclinical safety plans for Dyne's portfolio programs, supporting late discovery through first-in-human and proof-of-concept clinical studies of investigational antibody oligonucleotide therapeutics to treat serious muscle diseases. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as a preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease.

Cambridge, MA30+ days ago

$232,500–$335,833.33 Per Year

The Global Project Head is a senior leadership role within Sanofi's Global Preclinical Safety (PCS) organization, responsible for the direct management and strategic oversight of a team of project toxicologists supporting the Sanofi drug development portfolio. Maintain and apply deep expertise across core toxicology disciplines, including general toxicology, genetic toxicology, reproductive and developmental toxicology, carcinogenicity, immunotoxicology, and safety pharmacology.

Boston, MA27 days ago

$275,000–$300,000 Per Year

The successful candidate will work independently to direct their own program work, provide day-to-day scientific guidance to entry-level toxicology staff, and collaborate closely with peers across nonclinical and development functions. Deep expertise supporting small molecule programs across discovery, IND-enabling, and early clinical development, with demonstrated experience advancing CNS-active candidates.

Cambridge, MA30+ days ago

$232,500–$335,833.33 Per Year

Champion the development and qualification of novel in vitro models - including organoids, microphysiological systems (MPS/organ-on-chip), and advanced cell culture platforms - to investigate mechanisms of toxicity and understand human relevance. With direct oversight of laboratory operations in France and the United States, and digital capabilities in Germany, you will lead a truly global, multidisciplinary team united by a shared commitment to scientific excellence and patient safety.

Boston, MA30+ days ago

LocationNew York City, San Francisco, or BostonEmployment TypeFull timeLocation TypeHybridDepartmentScienceOverviewApplicationAt Inductive Bio we're tackling the challenge of making drug discovery more efficient. In this role, you will help shape our scientific offering, ensure that our models are rigorously validated, and guide us toward solutions that have meaningful impact in real-world drug discovery programs.

Worcester, MA30+ days ago

Scientist II Qualifications: Bachelor's Degree in toxicology or related discipline and typically 12 years of experience OR Master's Degree in toxicology or related discipline and typically 10 years of experience OR PhD in toxicology or related discipline and typically 4 years of experience. This includes toxicology support for extractables and leachables, health-based exposure limits (HBELs) including permitted daily exposure limits (PDEs) and occupational exposure limits (OELs), environmental risk assessments (ERA), and other contaminants.

Cambridge, MA18 days ago

$153,541–$230,312 Per Year

Manager level is expected to be between $131,035 and $196,553 annualized and the current base salary range for this position at the Associate Director level is expected to be between $153,541 and $230,312 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. The Global Safety Scientist will work closely with the Head of Safety Sciences and the Global Safety Leads and be responsible for leading and planning the development of aggregate safety reports, signal detection review, authoring and analyzing data for safety topic reports, and creation and update of risk management plans.

Cambridge Crossing, MA20 days ago

$137,570–$166,706 Per Year

Proficient with molecular and cellular biology related techniques, including but not limited to 2D/3D/spheroid cell culture and related cellular assays, Western blot and/or JESS, qRT-PCR, flow cytometry, proliferation and/or cytotoxicity assays (CyQuant, CTG, apoptosis, IncuCyte, etc.), ELISA, MSD and/or HTRF assays, colony formation assay, processing of DNA/RNA/protein, IP/Co-IP. In addition, the individual will coordinate with other functions, such as informatics and predictive science, lead discovery and optimization, in vivo pharmacology, and translational research teams to design/execute work related to patient stratification, identification of appropriate PD markers and assay development/transfer for miniaturization, among others to ensure timely project advancement.

Boston, MA30+ days ago

$163,500–$281,600 Per Year

Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). This individual will set the scientific direction for hair cell regeneration approaches, lead preclinical study design and execution, and collaborate cross-functionally within LGM to integrate regenerative strategies with the division's broader gene therapy capabilities.

Boston, MA26 days ago

$58,000–$123,200 Per Year

Apply a broad toolkit of molecular and bioanalytical techniques, including: PCR-based approaches (PCR, qPCR, ddPCR, stem-loop PCR, vg/dg dose quantification) for vector genome and transcript quantification; ELISA and immunoassays for protein expression and biomarker analysis; LC-MS-based quantitative bioanalysis where applicable; Immunohistochemistry (IHC) and tissue-based spatial analyses to enable regional CNS characterization; Next-generation sequencing (NGS) methods to support vector tracking, expression profiling, or integration-related analyses. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities).

Boston, MA30+ days ago

$129,000–$203,100 Per Year

The successful candidate will lead cross-functional projects, deliver production-grade models and agentic systems, and help establish governance and MLOps practices that ensure reproducibility, transparency, and ethical AI use in preclinical research. Hands-on experience with large language models and agentic AI frameworks (fine-tuning, prompt engineering, multi-agent orchestration, tool use, and API-based production orchestration) required.

Cambridge, MA22 days ago

$300,000–$500,000 Per Year

This leader oversees cross-functional initiatives from discovery through early clinical development, builds and mentors high-performing teams, and partners across the enterprise and with external collaborators to deliver transformative cell-based therapies. Familiarity with regulatory pathways for cell and gene therapies (e.g., FDA/EMA guidance, IND preparation, RMAT considerations), including in vivo gene therapy nonclinical packages (biodistribution, toxicology, shedding).

MA30+ days ago

Develop and implement cell-based and biochemical assays to assess receptor binding signaling endocytosis and trafficking to support novel ligand candidate derisking and selection. Expertise in characterizing receptor-ligand interactions and downstream cell signaling or cellular function readouts is highly desired.

Cambridge Crossing, MA20 days ago

$252,640–$306,137 Per Year

This leader will partner deeply with Research leadership and the Pharmacology, DMPK, Toxicology, and Translational Science units to deliver the applications, workflow capabilities, AI, and supporting data flows that enable non-clinical decisions across in-vivo biology, DMPK, ADME, non-clinical safety, toxicology, and bioanalytical science. Non-clinical pharmacology generates the evidence that determines which candidates enter humans, and this role matters now because scientists need better integrated applications, AI, and workflows to generate, interpret, and act on that evidence with greater speed and confidence.

Cambridge, MA30+ days ago

$145,000–$177,000 Per Year

D. in toxicology or a related field with 6+ years of pharma/biotech experience in nonclinical safety assessment, or an M.S. in toxicology or a related field with 10+ years of experience in nonclinical safety assessment, the ability to work independently, provide domain expertise and leadership, as well as cross-functionally in a fast-paced, matrixed environment with a positive, flexible attitude. Position Overview We are seeking an enthusiastic, self-motivated Senior Scientist to join the Nonclinical Development group, supporting the nonclinical safety assessment function for IND-enabling programs across Prime Medicines pipeline.

Cambridge, MA30+ days ago

$173,000–$234,000 Per Year

POSITION OVERVIEW:Disc Medicine's Drug Metabolism and Pharmacokinetics (DMPK) team is seeking an experienced scientist to support the application of pharmacokinetic (PK) and pharmacodynamic (PD) sciences in our drug discovery and development portfolios, with more focus on biologics programs. This role requires regular interaction with internal and external partners to ensure timely, high‑quality delivery of ADME/PKPD data and to drive DMPK strategy for both Discovery and Development programs.

Northampton, MA30+ days ago

Environmental Analyst II'',''Environmental Analyst II'',''United States-Massachusetts-Northampton-811 N King Street'',''United States-Massachusetts-Northampton-811 N King Street'',''Science'',''Science'',''Massachusetts Department of Transportation'',''Massachusetts Department of Transportation'',''Full-time'',''Full-time'',''Day'',''Day'',''May 15, 2026, 1:10:27 PM'',''May 15, 2026, 1:10:27 PM'',''1'',''1'',''115,592.95'',''82,398.26'',''115,592.95'',''Yearly'',''Derrick Mann'',''Derrick Mann'',''8572741935'',''DOT'',''DOT'',''No'',''No'',''Yes'',''Yes'',''false'',''1080039'',''1080039'',''true'',''1080039'',''false'',''Submission for the position: Stormwater and Wetlands Analyst (Environmental Analyst II) - (Job Number: 260002OY)'',''false'',''1080039'',''false'',''true''. Incumbents of positions in this series prepare and/or review scientific reports, studies and analytical data of environmental Impacts and environmental processes; perform calculations relating to environmental science problems; determine possible impacts on water, soil, air and public health; measure levels of pollution; identify sources of pollution; and perform related work as required.

West Boylston, MA30+ days ago

Environmental Analyst IV'',''Environmental Analyst IV'',''United States-Massachusetts-West Boylston-180 Beaman St'',''United States-Massachusetts-West Boylston-180 Beaman St'',''Science'',''Science'',''Department of Conservation & Recreation'',''Department of Conservation & Recreation'',''Full-time'',''Full-time'',''Day'',''Day'',''May 7, 2026, 3:21:15 PM'',''May 7, 2026, 3:21:15 PM'',''1'',''1'',''127,235.16'',''86,434.92'',''127,235.16'',''Yearly'',''Moneesha Dasgupta'',''Moneesha Dasgupta'',''6176450358'',''09-MOSES - Engineers/Scientists'',''09-MOSES - Engineers/Scientists'',''No'',''No'',''Yes'',''Yes'',''false'',''1082957'',''1082957'',''true'',''1082957'',''false'',''Submission for the position: Environmental Analyst IV, Water Resources - (Job Number: 2600032H)'',''false'',''1082957'',''false'',''true''. MINIMUM ENTRANCE REQUIREMENTS: Applicants must have at least (A) five years of full-time, or equivalent part-time, technical or professional experience in the field of environmental science, biology, chemistry, earth science, environmental health, meteorology, natural science, toxicology or public health, of which (B) at least three years must have been in a professional capacity, and of which (C) at least one year must have been in a supervisory, managerial or administrative capacity, or (D) any equivalent combination of the required experience and the following substitutions.

Boston, MA30+ days ago

Environmental Analyst IV'',''Environmental Analyst IV'',''United States-Massachusetts-Boston-1 Ashburton Place'',''United States-Massachusetts-Boston-1 Ashburton Place'',''Science'',''Science'',''Division of Capital Asset Management'',''Division of Capital Asset Management'',''Full-time'',''Full-time'',''Day'',''Day'',''May 13, 2026, 3:31:56 PM'',''May 13, 2026, 3:31:56 PM'',''1'',''1'',''127,235.16'',''86,434.92'',''127,235.16'',''Yearly'',''Nancy Daiute'',''Nancy Daiute'',''6176803880'',''09-MOSES - Engineers/Scientists'',''09-MOSES - Engineers/Scientists'',''No'',''No'',''Yes'',''Yes'',''false'',''1085911'',''1085911'',''true'',''1085911'',''false'',''Submission for the position: Environmental Project Manager - (Job Number: 260003PN)'',''false'',''1085911'',''false'',''true''. MINIMUM ENTRANCE REQUIREMENTS: Applicants must have at least (A) five years of full-time, or equivalent part-time, technical or professional experience in the field of environmental science, biology, chemistry, earth science, environmental health, meteorology, natural science, toxicology or public health, of which (B) at least three years must have been in a professional capacity, and of which (C) at least one year must have been in a supervisory, managerial or administrative capacity, or (D) any equivalent combination of the required experience and the following substitutions.

Boston, MA30+ days ago

Environmental Analyst V'',''Environmental Analyst V'',''United States-Massachusetts-Boston-100 Cambridge Street'',''United States-Massachusetts-Boston-100 Cambridge Street'',''Science'',''Science'',''Department of Environmental Protection'',''Department of Environmental Protection'',''Full-time'',''Full-time'',''Day'',''Day'',''Apr 30, 2026, 7:27:03 PM'',''Apr 30, 2026, 7:27:03 PM'',''1'',''1'',''137,394.40'',''93,270.84'',''137,394.40'',''Yearly'',''Chris Mendez / EEADiversity@mass.gov'',''Chris The Air Quality Branch Chief is responsible for development, maintenance and operation of computerized data collection systems for reporting programs such as the Environmental Results Program (ERP), Stage I, Underground Storage Tank Program, Air Quality Compliance & Enforcement activity reporting including reporting of High Priority Violators and Federally reportable violators to EPA data systems (ICIS, ECHO).

Boston, MA11 days ago

Environmental Analyst IV'',''Environmental Analyst IV'',''United States-Massachusetts-Boston-10 Park Plaza'',''United States-Massachusetts-Boston-10 Park Plaza'',''Science'',''Science'',''Massachusetts Department of Transportation'',''Massachusetts Department of Transportation'',''Full-time'',''Full-time'',''Day'',''Day'',''Jun 12, 2026, 11:18:35 AM'',''Jun 12, 2026, 11:18:35 AM'',''1'',''1'',''139,539.14'',''98,580.74'',''139,539.14'',''Yearly'',''Derrick Mann'',''Derrick Mann'',''8573688541'',''DOT'',''DOT'',''No'',''No'',''Yes'',''Yes'',''false'',''1054836'',''1054836'',''true'',''1054836'',''false'',''Submission for the position: Construction Compliance Coordinator (Environmental Analyst IV) - (Job Number: 250007J3)'',''false'',''1054836'',''false'',''true''. The work associated with this position includes environmental impact analysis, permit and/or amendment application review, review of constructed mitigation monitoring reports, field work to evaluate construction period environmental issues and facilitate solutions, collaboration with internal and external stakeholders to develop innovative solutions to complex problems, and analyzing construction-period stormwater management to maintain compliance on projects.

Cambridge, MA28 days ago

$236,250–$341,250 Per Year

In these roles, duties include: Design safe, rapid and informative First-In-Human studies for oncology assets potentially including natural history, experimental model validation, mechanistic and signal seeking, streamlined Proof-of-Mechanism as well as Proof-of-Concept studies providing robust data for early Go/No Go decisions and other pharmacokinetic studies. A key focus of this role is to support the path from the research phase through early clinical development including early and rapid Proof-of-Mechanism/Proof-of-Concept, as well as natural history studies and experimental model validation to contribute to Human Target Validation (HTV) and evaluating the pharmacology of novel therapeutic approaches.

Cambridge, MA16 days ago

$145,000–$177,000 Per Year

D. in toxicology or a related field with 6+ years of pharma/biotech experience in nonclinical safety assessment, or an M.S. in toxicology or a related field with 10+ years of experience in nonclinical safety assessment, the ability to work independently, provide domain expertise and leadership, as well as cross-functionally in a fast-paced, matrixed environment with a positive, flexible attitude. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types.

Cambridge, MA30+ days ago

$168,000–$220,500 Per Year

You will thrive in an environment where you can share expertise across functions and global UCB sites, engage with cutting-edge science and build collaborative networks to drive cross-functional success. This role is well suited to an experienced toxicologist-ideally with exposure to gene and cell therapy or other novel modalities-who enjoys working at the interface of science, development strategy, and regulation.

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Toxicology Jobs in Massachusetts

Vice President Toxicology Alnylam Pharmaceuticals Inc

Director / Associate Director – Toxicology Monte Rosa Therapeutics, Inc

Executive Director, Head of Toxicology Centessa Pharmaceuticals Plc

Director / Associate Director - Toxicology Monte Rosa Therapeutics Inc

Senior Director, Development Pharmacology & Toxicology Intellia Therapeutics Inc

Sr. Scientist- Toxicology StratAcuity Staffing Partners Inc

Associate Director / Director, Toxicology Beam Therapeutics

Associate Director, Toxicology (Nonclinical Safety Evaluation) City Therapeutics

Associate Director / Director, Toxicology Beam Therapeutics Inc

Toxicology Research Scientist Vertex Pharmaceuticals

Pioneering Medicines: Senior Director, Head of Toxicology Flagship Pioneering Inc

Sr. Scientist/Principal Scientist, Toxicology (Small Molecule) Antares Therapeutics

Associate Director / Director, Toxicology Korro Bio Inc

Principal Scientist, Toxicology Dyne Therapeutics Inc

Global Project Head, Toxicology Sanofi

Senior Director, Toxicology CNS Specialist Centessa Pharmaceuticals Plc

Head of Toxicology Innovation Sanofi

Toxicologist Inductive Bio Inc

Senior Scientist II Occupational & Environmental Toxicologist AbbVie Inc

Senior Manager/Associate Director, Global Safety Scientist, MSRM Agios Pharmaceuticals Inc

Senior Scientist, Discovery Biology Oncology Bristol-Myers Squibb Co

Director, Regenerative Biology Eli Lilly and Co

Postdoctoral Scientist - Gene Therapy Biodistribution & Molecular Biology (CNS) Eli Lilly and Co

Senior Specialist, Data Science Merck & Co Inc

Head of Regeneron Cell Medicines Regeneron Pharmaceuticals Inc

Scientist Investigative Sciences Alnylam Pharmaceuticals Inc

Senior Dir, In-Vivo & Non-Clinical Pharmacology Bristol-Myers Squibb Co

Senior Scientist, Safety Assessment Prime Medicine Inc

Principal Scientist/Associate Director, DMPK Disc Medicine Inc

Stormwater and Wetlands Analyst (Environmental Analyst II) Commonwealth of Massachusetts

Environmental Analyst IV, Water Resources Commonwealth of Massachusetts

Environmental Project Manager Commonwealth of Massachusetts

Air Quality Branch Chief Commonwealth of Massachusetts

Construction Compliance Coordinator (Environmental Analyst IV) Commonwealth of Massachusetts

Senior Clinical Lead, Early Clinical & Experimental Therapeutics Sanofi

Senior Scientist, Safety Assessment Prime Medicine

Non-Clinical Safety Lead - Cambridge, MA UCB SA

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