The Senior Manager, DSPV will also support safety scientist activities, including medical review of ICSRs, clinical safety data review, signal detection and assessment, preparation and review of aggregate safety reports, review of safety information in clinical and regulatory documents, and contribution to risk management and product labeling activities. Support routine safety signal management activities, including review of adverse event data, aggregate data, literature, regulatory information, and other relevant safety sources; evaluation, validation, assessment, documentation, and tracking of potential safety signals in accordance with company procedures and applicable global regulatory requirements.