Life Science Research Professional 1

Note: This position has been deemed critical by the School of Engineering Dean's Office and is exempt from the hiring freeze. This is a two (2) year fixed term position. Visa sponsorship is not available for this position. All candidates must be eligible to work and live in the U.S.

Work Arrangement: This position is onsite, working at the Stanford main campus.

Budgeted Salary: The budgeted base salary range for this position is $32.87 to $40.52 per hour.

The School of Engineering

Stanford Engineering has been at the forefront of innovation for over a century, creating pivotal technologies that have transformed the worlds of information technology, communications, health care, energy, business and beyond. Our faculty and students are creative risk-takers who pursue excellence across a breadth of disciplines. Our alumni include some of the world''s most successful leaders in technology and business. Our staff are critical to enabling Stanford Engineering to accomplish its mission: seeking solutions to some of the world''s most urgent challenges and educating leaders who will make the world a better place through the power of engineering principles, techniques and systems.

The Chemical Engineering Department was founded in 1961, and it was initially an outgrowth of the university's Department of Chemistry. Early faculty pioneered or substantially influenced the emerging field of chemical engineering in many vital areas, including catalysis and transport/fluid mechanics. More recently, the department has added bioengineering and soft-material science to its core areas of excellence and has made a growing commitment to technology development that complements its long-held strength in fundamental applied science and molecular engineering. (Chemical Engineering website: https://cheme.stanford.edu/ )

The Abu-Remaileh Lab in the Department of Chemical Engineering at Stanford University is seeking a Life Science Research Professional 1 to conduct research on lysosomal biology and lipid metabolism, with a focus on neurodegenerative and lysosomal storage diseases. For more information, please visit https://www.abu-remaileh.com.

This position offers the opportunity to independently conduct research utilizing mouse models of disease, alongside cell-based systems, organelle isolation, and mass spectrometry-based lipidomics. The successful candidate will contribute original scientific insights to projects investigating how lysosomal dysfunction drives disease pathology.

The primary responsibilities for this position include managing a mouse colony, harvesting and processing tissues, performing histological studies and confocal microscopy, maintaining mammalian tissue cultures, conducting PCR and gel electrophoresis for genotyping, executing Western blot analyses, preparing samples for liquid chromatography/mass spectrometry (LC/MS) experiments, and analyzing data. A minimum commitment of two years is required for this role.

Additionally, the candidate will plan and execute experiments to support ongoing research projects, maintain organized records of experiments and outcomes, and perform mouse husbandry, dosing, and tissue collection in accordance with approved protocols.

The role involves executing standard molecular and cell biology techniques, including PCR, gel electrophoresis, Western blotting, and immunostaining. The candidate will also prepare samples for LC/MS-based analyses, perform histological preparations, and conduct confocal imaging. Quantifying and analyzing image data, as well as contributing to the preparation of written documents such as protocols, presentations, and manuscripts, is essential.

Overall, this Life Science Research Professional 1 position presents an outstanding opportunity for someone eager to engage deeply in collaborative research.

Preferred Requirements:

• Bachelor's degree in Bioengineering, Chemical Engineering, Biochemistry, Molecular Biology, Genetics, Neuroscience, or a related area.
• A minimum of one year of laboratory research experience.
• Hands-on experience with mice, including colony management, genotyping, and processing animal tissues.
• Proficiency in mammalian cell culture techniques.
• Familiarity with molecular and cell biology methods, including PCR, qPCR, immunostaining, and Western blotting.
• Experience with histology, confocal microscopy, or image quantification using Fiji/ImageJ is a plus.
• Prior experience with sample preparation for mass spectrometry is an advantage.
• Strong reliability with record-keeping and organizational skills.

Physical Requirements include:

• Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
• Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
• Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
• Must have correctible vision to perform duties of the job.
• Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
• Ability to lift heavy objects weighing up to 50 pounds.
• Ability to work in a dusty, dirty, and odorous environment.
• Position may require repetitive motion.

Working Conditions:

• May require working in close proximity to blood borne pathogens.
• May require work in an environment where animals are used for teaching and research.
• Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
• Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
• May require extended or unusual work hours based on research requirements and business needs.

Core Duties:

• Plan approach to experiments in support of research projects in lab and/or field based on knowledge of scientific theory.

• Independently conduct experiments; maintain detailed records of experiments and outcomes.

• Apply the theories and methods of a life science discipline to interpret and perform analyses of experiment results; offer suggestions regarding modifications to procedures and protocols in collaboration with senior researcher.

• Review literature on an ongoing basis to remain current with new procedures and apply learnings to related research.

• Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.

• Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.

• Assist with orientation and training of new staff or students on lab procedures or techniques.

Minimum Education and Experience

Bachelor''s degree in related scientific field.

Knowledge, Skills and Abilities:

• General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.

• Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.

• Ability to maintain detailed records of experiments and outcomes.

• General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.

• Ability to work under deadlines with general guidance.

• Excellent organizational skills and demonstrated ability to accurately complete detailed work.

Core Duties:

• Plan approach to experiments in support of research projects in lab and/or field based on knowledge of scientific theory.

• Independently conduct experiments; maintain detailed records of experiments and outcomes.

• Apply the theories and methods of a life science discipline to interpret and perform analyses of experiment results; offer suggestions regarding modifications to procedures and protocols in collaboration with senior researcher.

• Review literature on an ongoing basis to remain current with new procedures and apply learnings to related research.

• Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.

• Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.

• Assist with orientation and training of new staff or students on lab procedures or techniques.

Minimum Education and Experience

Bachelor''s degree in related scientific field.

Knowledge, Skills and Abilities:

• General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.

• Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.

• Ability to maintain detailed records of experiments and outcomes.

• General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.

• Ability to work under deadlines with general guidance.

• Excellent organizational skills and demonstrated ability to accurately complete detailed work.