Principal ADS Program Lead GenentechPrincipal ADS Program LeadBoston, MassachusettsIn addition to overseeing day-to-day delivery, the Analytical Data Science Program Lead is accountable for a broad range of analytical outputs including but not limited to: exploratory analyses, application development and dynamic visualization to enable ongoing data review and scientific insights generation. This role leads a team of highly skilled programmers and junior leaders, ensuring the delivery of high-quality, regulatory-compliant analytical outputs that support key development milestones and health authority submissions.
Senior Principal Scientist -Bioanalytical Assay- Cell Therapy GenentechSenior Principal Scientist -Bioanalytical Assay- Cell TherapyD. in Immunology, Cell Biology, Biochemistry, Pharmacology, Bioanalytical Sciences, or a related life sciences discipline with a minimum of 7 years’ experience in the field of drug discovery or development with extensive biopharmaceutical industry experience leading bioanalytical strategy across discovery, translational research, and clinical development. As the cell therapy bioanalytical subject matter expert, this role will partner across Bioanalytical Sciences, Research, Translational Medicine, Clinical Development, CMC, Regulatory, and Computational Sciences to identify and prioritize the key scientific questions required to advance cell therapy programs.
Principal Scientist, Peptide Therapeutics GenentechPrincipal Scientist, Peptide TherapeuticsSynthetic Mastery: Utilize expert-level skills in solid-phase peptide synthesis, solution-phase organic chemistry, and specialized macrocyclization or ligation strategies. In this lab-based leadership role, you will combine hands-on synthetic expertise with strategic oversight, driving the discovery and optimization of peptide therapeutics across the full development lifecycle.
Senior Medical Science Liaison, Metabolic Dysfunction-Associated Steatohepatitis (MASH) Pipeline (Southeast) GenentechSenior Medical Science Liaison, Metabolic Dysfunction-Associated Steatohepatitis (MASH) Pipeline (Southeast)FloridaIn collaboration with home office and regional partners, MASH Pipeline MSLs are accountable for comprehensive activities focused on delivering a successful clinical development program including, but not limited to: clinical trial recruitment focused activities, competitive intelligence, congress support, professional society engagement, and therapeutic area landscaping. The Metabolic dysfunction-associated steatohepatitis (MASH) Pipeline Medical Science Liaison, a part of the Cardiovascular, Renal and Metabolism (CVRM) MSL team, is a credible field medical partner responsible for providing clinical, scientific and other relevant information related to disease states and the appropriate utilization of Genentech medicines in the MASH pipeline.
Senior Scientist - Nucleic Acids Payload Engineering GenentechSenior Scientist - Nucleic Acids Payload EngineeringSan Diego, CaliforniaCore Technical Skills: Candidates must possess expertise in advanced nucleic acid manipulation and molecular cloning methods, such as IVT, mammalian expression vector design, library design & cloning, Golden Gate cloning, SDM, and Gibson assembly. We are looking for an outstanding molecular biologist who possesses significant experience in gene engineering and nucleic acid biology, specifically focused on enhancing DNA delivery and nuclear shuttling and mitigation of DNA-mediated immunogenicity.
Principal Scientist, Lab Head, Synthetic Immunity GenentechPrincipal Scientist, Lab Head, Synthetic ImmunityLeadership and Collaboration: Exceptional leadership abilities with a proven track record of working with multidisciplinary teams, excellent written and verbal communication skills, and a collaborative spirit to work closely with cross-functional research teams. The successful candidate will lead a highly productive research team and integrate efforts across cross-functional teams to identify new targets and therapeutic hypotheses, and to advance transformative medicines using Synthetic Immunity approaches.
Imaging AI Scientist GenentechImaging AI ScientistCalifornia$124,800–$231,800 / yearThe new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. We're seeking an Imaging AI Scientist to join Imaging Data Insights, applying machine learning and modern AI to turn imaging data into reusable tools, scalable workflows, and better decisions across drug development.
IT OT Manufacturing Systems Application Engineer GenentechIT OT Manufacturing Systems Application EngineerHillsboro, OregonAs part of the Hillsboro IT OT team, you will report to the Manufacturing Systems Operations Lead and take the System Ownership and local Product Ownershipaccountabilities for Manufacturing IT/OT Applications and ensure the support of Product Transfers and Make/Assess/Release in a24x7 Goods Manufacturing Practice (GMP) environment. In collaboration with IT Business Partners, monitor and improve stakeholder and userexperience and ensure strong support of Product Transfers and Make/Assess/Release.
RWD Scientist GenentechRWD ScientistBoston, MassachusettsThis role is based in the Real-World & Clinical Data Strategy (RWCDS) team which drives data excellence and analytics to power enhanced decision-making and evidence-generation within Roche Product Development. You build expertise in novel data types, statistical methods, and analytical methodology, which may include advanced analytics, special trial designs and types, and data handling methods.
Senior Statistician, Early Development GenentechSenior Statistician, Early DevelopmentEarly Development Biometrics is also home to Methods Collaboration & Outreach (MCO), which enables the most impactful use of quantitative methodology across PDD through internal consultation, external collaboration, and continuous capability building; and Visual Analytics, which creates and maintains interactive dashboards that drive high-quality Medical Data Review (MDR) and safety signal detection, aligned with Risk-Based Quality Management (RBQM) principles and Critical-to-Quality (CtQ) endpoints. As trusted partners in early development, we design efficient and innovative clinical trials, apply rigorous statistical methods, and implement high-quality programming and analytical solutions to accelerate timelines, de-risk development, and increase the probability of technical success.
Master Manufacturing Techncian, Packaging GenentechMaster Manufacturing Techncian, PackagingHolly Springs, North CarolinaIn partnership with the Engineering and the start-up project (user) team, you will partner and collaborate with our partner organizations (Engineering and MSAT, Quality, Supply Chain, Technical Development, Regulatory, CMO, Strategy) to provide input as the end-user for activities related to design and start-up a new Drug Product Fill and Finish facility. This plant meets today’s demand for CVRM (Cardiovascular, Renal, and Metabolism) medicines and is scalable to grow with the portfolio, which focuses on next-generation metabolic medicines specifically targeting the global obesity epidemic and Type 2 diabetes.
Postdoctoral Fellow - Discovery Oncology, Foster Lab GenentechPostdoctoral Fellow - Discovery Oncology, Foster LabThe program provides ample opportunities to present your work both internally and externally, career development support, and exposure to an environment with a broad focus, ranging from basic science to drug development, with the goal to accelerate breakthrough discoveries. The Foster Lab is dedicated to deciphering the mechanistic connection underlying novel cancer cell dependencies and synthetic lethal interactions that offer high potential for therapeutic exploitation.
Lead Medical Director, Product Development, Hematology GenentechLead Medical Director, Product Development, HematologyBoston, MassachusettsYou have a solid understanding of Phase II – III drug development (e.g trials across different stages of development, or formal education/qualifications in pharmaceutical medicine or drug development); have made significant contributions to an organization’s drug development (whether at Roche or another organization); have identified and created clinical development strategies that have led to label-enabling outcomes. You will be responsible to ensure strategic and operational alignment of the CDP with the relevant CD strategy, strategic and annual LCP; you will work with other CST members and relevant sub-teams to develop CDP components (e.g., analytics/data strategy, KOL development, publications strategy, etc.).
ADS Programmer (Boston, On-Site) GenentechADS Programmer (Boston, On-Site)Boston, MassachusettsIn addition to supporting regulatory submissions, the ADS Programmer plays a critical role in generating data insights through platforms such as the Insight Engine, enabling real-time exploration and interpretation of diverse clinical and exploratory data. We identify, influence, and adopt industry-leading digital and automation solutions, develop analytical approaches to support exploratory analyses, and align statistical programming practices across both early- and late-stage clinical development.
Head, Regulatory Program Management GenentechHead, Regulatory Program ManagementPartnering with the OnePDR Leadership Team, you will contextualize the regulatory landscape, ensure financial stewardship over PDR budgets, architect long-term capability strategies, and lead global Health Authority interactions to advance life-saving medicines for patients worldwide. As the Head, Regulatory Program Management , you will serve as a transformational executive leader holding dual accountability for Chapter capability development and end-to-end global regulatory execution across the entire Roche Pharmaceuticals portfolio (medicinal products and devices).
Director/Executive Director - gRED Center GenentechDirector/Executive Director - gRED CenterIf you're a seasoned construction leader with 15+ years managing large-scale, complex projects in California, possess exceptional executive presence, and thrive on building high-performing teams in ambiguous, high-stakes environments, this role offers the chance to leave a lasting legacy at one of the world's leading life sciences organizations. Genentech is seeking an exceptional Project Director/Executive Director to lead one of our most transformative capital initiatives: the conception and delivery of a groundbreaking 1.25M square foot research campus comprising seven state-of-the-art buildings at our South San Francisco headquarters.
Principal Maintenance Specialist, Packaging - CVRM (Holly Springs) GenentechPrincipal Maintenance Specialist, Packaging - CVRM (Holly Springs)Holly Springs, North CarolinaWe're seeking a highly skilled Maintenance Specialist with direct Pharmaceutical Packaging Equipment experience who will be accountable for leading troubleshooting and issue resolution for highly complex mechanical challenges, providing coaching / mentorship / training of other Facilities personnel, and serve as owners or functional representatives on projects. The new site will focus on large volume low cost Drug Product manufacturing (Component Prep & Compounding, Liquid PFS Filling, Automated Inspection, Autoinjector Assembly, Packaging/Finished Products).
Principal Supply Chain Data Scientist GenentechPrincipal Supply Chain Data ScientistLouisville, KentuckyPerformance Monitoring, Accurate Reporting, Improvement, and Problem Solving: Track key performance indicators (KPIs) such as on-time delivery rates, inventory turns, and order fulfillment rates to identify areas for improvement. Based at our main US Distribution facility in Louisville, Kentucky, this role goes beyond traditional data analysis to design predictive and prescriptive models, fostering innovation in supply chain strategy and decision-making.
Postdoctoral Fellow - Cell Line Development, Lu & Ng Labs GenentechPostdoctoral Fellow - Cell Line Development, Lu & Ng LabsYou will gain exposure to the drug development pipeline and help overcome current large-scale manufacturing challenges, ultimately reducing the cost of goods (COGs) to make life-changing gene therapies commercially viable and accessible to much larger patient populations. You will have opportunities to productively collaborate with other researchers across gRED (Genentech Research and Early Development), pRED (Roche), PTCG (Pharma Technical Gene Therapies), and PTD (Pharma Technical Development), present your work to project teams, and contribute to scientific publications.
Global MSAT Senior DP Product Steward GenentechGlobal MSAT Senior DP Product StewardHillsboro, OregonYour main responsibilities cover Technical Industrialization (Develop Technical Strategic Roadmap), Product Technical Health Management (Own & Mitigate Technical Risks) and Technical Leadership: Provide technical oversight of commercial DPs from launch to divestment to consistently deliver quality products to patients. The Senior Large Molecule DP Product Steward is responsible for driving seamless technical industrialization and sustaining and improving the technical health of commercial products, starting from manufacturability decision through process performance qualification (PPQ), supply maturity and optimization, and ultimately divestment.