Machine Learning Engineer (Staff & Principal) Tubi, Inc.Machine Learning Engineer (Staff & Principal)San Francisco, CA$239,000–$342,000 / yearFor all full-time, regular employees, in lieu of FOX Paid Parental Leave, Tubi offers a generous Parental Leave Program, which allows parents twelve (12) weeks of paid bonding leave within the first year of birth, adoption, surrogacy, or foster placement of a child in addition to applicable government leave program(s) and FOX's short-term disability policy. As a senior technical expert, you will tackle complex problems in machine learning at scale, collaborating closely with cross-functional teams to develop and optimize machine learning-driven solutions.
Principal Product Designer, Spending Chime Capital, LLCPrincipal Product Designer, SpendingSan Francisco, CARemoteYou will play a key role in shaping the quality and direction of design within the Chime app-advocating for thoughtful, member-centered solutions and partnering closely with cross-functional teams to deliver meaningful impact. We each bring an owner's mindset to our work, refusing to be outdone and holding ourselves accountable to meet and exceed the highest bars for our teams, our company, and our members.
NewPrincipal Scientist, Drug Product Process Science Allogene TherapeuticsPrincipal Scientist, Drug Product Process ScienceSouth San Francisco, CA$155,000–$180,000 / yearThe successful candidate will play a critical role in drug product process characterization and BLA readiness for allogeneic CAR-T therapies, including but not limited to process characterization design and execution, and regulatory‑ready documentation in support of BLA‑enabling and BLA submission activities, and will work closely with cross‑functional partners across MSAT, Quality, Regulatory, Analytical Sciences, and Clinical Operations. Experience working in the pharmaceutical or biotechnology industry that includes elements of new product development, process characterization, formulation development, equipment design and implementation, technology transfers, statistical process control (SPC), and statistical design and analysis of experiments.
NewMarketing Principal Systems & Data Analyst (Growth) Culture AmpMarketing Principal Systems & Data Analyst (Growth)San Francisco, CA$140,000–$170,000 / yearYou'll join our Systems & Data team within Lifecycle & Marketing Operations, working alongside our Marketing Systems Architect, who owns stack architecture and integrations, and our Marketing Operations team, who manage day-to-day platform administration. Our Growth Marketing team runs on a modern stack: HubSpot, Salesforce, Qualified, 6sense, Outreach, Amplitude, and Looker, and we're looking for a senior, hands-on individual contributor, a Principal Systems & Data Analyst, to become the person who makes that stack trustworthy.
Principal Solutions Architect ZyphraPrincipal Solutions ArchitectSan Francisco, CaliforniaBuilding and maintaining a library of reusable technical assets: model evaluation frameworks, fine-tuning guides, deployment architectures, API integration playbooks, and use-case demos that accelerate how partners and customers adopt Zyphra's models. Deep technical fluency across one or more of Zyphra’s core domains: large language models and model architecture, multimodal AI, speech and audio synthesis, brain-computer interfaces and neural signal processing, or agentic AI systems.
Principal Power Engineer Cowboy SpacePrincipal Power EngineerSan Carlos, CaliforniaOur satellites operate in Low Earth Orbit to collect sunlight and enable a new class of capabilities—from powering on-orbit compute, to transmitting energy via infrared lasers (space-to-earth and space-to-space), powering on-orbit compute to delivering secure, high-bandwidth optical data. Export Control Requirement: To conform to U.S. Government space technology export regulations, including the International Traffic in Arms Regulations (ITAR), applicants must be a U.S. citizen, lawful permanent resident of the U.S., protected individual as defined by 8 U.S.C. 1324b(a)(3), or eligible to obtain the required authorizations from the U.S. Department of State.
Principal Technical Program Manager Hayden AIPrincipal Technical Program ManagerSan Francisco, CaliforniaBusiness-Engineering Translation: Serve as the primary interface between executive leadership and engineering teams, translating business commitments (contracts, growth targets, customer deployments) into engineering capacity plans and surfacing tradeoffs before they become misses. Cross-Functional Program Delivery: Drive end-to-end delivery of strategic programs that span multiple engineering pillars and business functions, including customer-facing deployments, new product launches, and operational scaling initiatives.
Principal Product Manager, AI DrataPrincipal Product Manager, AISan Francisco, California$207,700–$256,600 / yearYou’ll sit in the AI Pillar , working across Product, Engineering, Design, GRC, and GTM teams to define, build, and scale AI agents that operate safely in customers’ environments and deliver measurable outcomes in areas like TPRM, evidence collection, control mapping, and reporting. This is a principal-level role: you will shape strategy across multiple teams, create operating models for AI delivery at scale, and coach senior PMs while serving as a company-level evangelist for Drata’s AI-enabled product vision.
Senior Or Principal Nuclear Medicine Technologist - Perm - San Francisco, CA VitalHireSenior Or Principal Nuclear Medicine Technologist - Perm - San Francisco, CASan Francisco, CA$166,000–$226,000 / yearMust be able to independently perform all routine PET/CT exams and at least 3 of the following specialty exams:Multiphase CT, Pediatric, Cardiac, Neuro, or Research PET/CT. A leading Medical Center is hiring 2 Senior/Principal Nuclear Medicine Fusion Technologists to join its PET/CT team.
Principal Infrastructure Architect DigitalOceanPrincipal Infrastructure ArchitectSan Francisco, CARemote$184,000–$231,000 / yearDefining and owning DigitalOcean's hardware architectures for next-generation compute environments across our CPU, GPU, Storage, and Infrastructure Server SKU products, navigating shifts in technology, networking topologies, and AI/ML requirements. Architecting end-to-end storage topologies with vendor teams to support diverse workloads across performance, capacity, and archival tiers, moving from direct-attached to disaggregated and software-defined storage.
Principal Engineer, Data Center Architect DigitalOceanPrincipal Engineer, Data Center ArchitectSan Francisco, CARemote$184,000–$231,000 / yearWhat You'll Be Doing: Defining and owning DigitalOcean's reference architectures for next-generation Data Center environments, navigating shifts in technology, networking topologies, and AI/ML hardware roadmaps to keep facility designs future-proofed. Architecting end-to-end power topologies with vendor teams to support diverse hardware across medium to ultra-high-density rack deployments, moving from 415VAC to 800VDC.
Principal Product Manager, Identity ZipPrincipal Product Manager, IdentitySan Francisco, CA$200,000–$280,000 / yearYou will define and deliver platform-level features that support our largest enterprise customers, ensure world-class security and governance, and enable teams across Zip to build consistent, performant, and compliant product experiences. Zip's team includes product leaders from Apple, Airbnb, and Meta, as well as former procurement leaders from United Health, Sanofi, MGM Resorts, Discover, and NASA.
Principal Deposits Patelco Credit UnionPrincipal DepositsDublin, California$137,485–$171,866 / yearFull timeAs a recognized subject matter expert and emerging executive leader, the Principal, Deposits influences enterprise-wide decisions, partners with senior leadership across the organization, and drives initiatives that impact member experience, balance sheet performance, and organizational growth. This role serves as a key advisor to executive leadership and is accountable for developing and executing enterprise deposit strategies that support growth, customer acquisition, funding objectives, profitability, and competitive differentiation.
Vice President / Principal – Co-Founder Track | AI-Native Healthcare Private Equity | Onsite SF KatharinaVice President / Principal – Co-Founder Track | AI-Native Healthcare Private Equity | Onsite SFSan Francisco, California$200,000–$300,000 / yearFounded by Katharina Juenger, who previously built and sold Germany’s leading telemedicine platform, Cade is redefining how healthcare businesses scale - by combining deep healthcare expertise with advanced AI and automation. You will work shoulder-to-shoulder with the founder to source, structure, and execute control investments in healthcare, and help build a differentiated buyout firm from the ground up.
Principal Power Delivery Engineer - AI System Hyve SolutionsPrincipal Power Delivery Engineer - AI SystemFremont, CaliforniaTechnical expertise: Deep knowledge of DC/DC conversion, multiphase VR design, 48V/54V architectures, PDN design and analysis, magnetics, and power component selection; experience with power simulation and bench characterization (electronic loads, oscilloscopes, thermal tools). This Principal-level individual contributor role owns the architecture, design, and validation of power delivery for Hyve's AI and compute server platforms—from 48V/54V input and intermediate bus conversion through point-of-load regulation for GPUs, CPUs, and memory.
Principal Systems & Data Analyst Culture AmpPrincipal Systems & Data AnalystSan Francisco, CA$140,000–$170,000 / yearYou'll join our Systems & Data team within Lifecycle & Marketing Operations, working alongside our Marketing Systems Architect, who owns stack architecture and integrations, and our Marketing Operations team, who manage day-to-day platform administration. Our Growth Marketing team runs on a modern stack: HubSpot, Salesforce, Qualified, 6sense, Outreach, Amplitude, and Looker, and we're looking for a senior, hands-on individual contributor, a Principal Systems & Data Analyst, to become the person who makes that stack trustworthy.
Principal Counsel, Corporate PerplexityPrincipal Counsel, CorporateSan Francisco, CaliforniaBuild and scale corporate legal infrastructure, including consent and resolution precedent libraries, grant and vesting exhibit templates, signature and approval workflows, entity management systems, and formation and foreign-qualification processes for domestic and international expansion. This is a high-impact, hands-on role for a corporate attorney who thrives in fast-paced environments, is comfortable being the first and only owner of a workstream, and is excited to help build a best-in-class legal function at one of the most consequential AI companies in the world.
Principal Scientist, Drug Substance-Process Science/Immunology Allogene TherapeuticsPrincipal Scientist, Drug Substance-Process Science/ImmunologySouth San Francisco, CA$155,000–$180,000 / yearLed by a management team with significant experience in cell therapy, Allogene is developing a pipeline of “off-the-shelf” CAR T cell product candidates with the goal of delivering readily available cell therapy on-demand, more reliably, and at greater scale to more patients. Allogene Therapeutics, with headquarters in South San Francisco, is a clinical-stage biotechnology company pioneering the development of allogeneic chimeric antigen receptor T cell (AlloCAR T) products for cancer and autoimmune disease.
Principal Program Manager, TDI OktaPrincipal Program Manager, TDISan Francisco, CA$188,000–$258,500 / yearAs Okta continues to scale AI across the enterprise, we are seeking a highly technical, strategic, and execution-focused Principal Program Manager to lead complex, cross-functional programs across Technology, Data, and Intelligence (TDI). You will partner across Engineering, Product, Infrastructure, Security, Data, Finance, and Business teams to align strategy, establish scalable operating models, and drive predictable execution across large, interconnected programs.
Principal Applied Scientist Elevance HealthPrincipal Applied ScientistWalnut Creek, CaliforniaThe Principal Applied Scientist is responsible for leading the design, development, deployment, and scaling of advanced artificial intelligence and machine learning solutions that drive enterprise transformation and measurable business outcomes. We are a Fortune 25 company with a longstanding history in the healthcare industry, looking for leaders at all levels of the organization who are passionate about making an impact on our members and the communities we serve.