Staff Mechanical Design Engineer, EPC Redwood Materials IncStaff Mechanical Design Engineer, EPCSan Francisco, CA$187,500–$247,500 / yearDesign ownership for a wide range of mechanical and plumbing systems including, but not limited to: industrial/non-potable water, HVAC systems (labs, offices, industrial plants), process heating / cooling systems humidifiers, dehumidifiers, abatement systems (dust collectors, scrubbers), cooling towers, fans/pumps, plumbing, etc. Working knowledge of designing the following equipment types: condenser fluid heat rejection systems, chillers, boilers, air handling units, air and water source heat pumps, dust collectors, humidifiers, dehumidifiers, fans, and pumps.
Senior Mechanical Engineer, Ground Systems Motive CompaniesSenior Mechanical Engineer, Ground SystemsAlameda, CA$130,000–$160,000 / yearThe team works across the full design cycle, from P&IDs and component selection to integration and testing, covering a range of fluids including cryogenics, high-pressure gases, and pyrophorics. The Ground Systems Fluids Team designs and builds fluid systems for propellant handling, propulsion support, and payload conditioning.
Senior Manager, Battery R&D Blue Current IncSenior Manager, Battery R&DHayward, CA$167,032–$182,946 / yearFree of flammable liquid electrolytes, Blue Currents fully dry, inherently safe batteries significantly reduce risks to human and environmental health while providing a higher-performance alternative to traditional lithium-ion batteries. The ideal candidate combines deep cathode and electrode expertise with strong people and program leadership, enabling effective execution, data-driven decision-making, and effective risk management.
Director, Formulations Cytokinetics IncDirector, FormulationsSouth San Francisco, CA$232,110–$270,795 / yearCytokinetics is a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction. You will play a key role in advancing our drug development programs by leading efforts in formulation development, process optimization and scale-up, control strategy development, and development and GMP manufacturing activities at external CDMO partners.
Site Leader/ Operations Director - Peptide API Hims & HersSite Leader/ Operations Director - Peptide APIMenlo Park, CaliforniaHands-on technical expertise with solid-phase peptide synthesis (SPPS), peptide purification (HPLC), and downstream processing, with the ability to troubleshoot complex manufacturing challenges. This role is responsible for establishing/enhancing production processes, implementing/modifying GMP systems, and leading day-to-day manufacturing activities.
Principal Scientist, Purification Process Development Denali TherapeuticsPrincipal Scientist, Purification Process DevelopmentSouth San Francisco, CA$159,000–$207,000 / yearDenali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients. Qualifications/Skills: Typically requires a PhD in Biology, Biochemistry, Chemical Engineering or related scientific discipline, plus 10+ years' of related work experience.
NewPrincipal Scientist, CMC Analytical Development - Commercial Products Denali Therapeutics IncPrincipal Scientist, CMC Analytical Development - Commercial ProductsSouth San Francisco, CA$159,000–$207,000 / yearAs the product transitions into routine commercial production and Denali pursues marketing applications in additional countries, we are seeking a Principal Scientist to join our Large Molecule Analytical Development Team to serve as a Commercial Analytical Lifecycle Lead. The Commercial Analytical Lifecycle Lead is expected to partner closely with peer Late Stage Analytical Development and Bioassay Development Leads responsible for driving successful analytical transfer & registration of a second-source manufacturing and QC site.
NewPrincipal Scientist, Commercial & Late-Stage Cell Culture Process Development Denali Therapeutics IncPrincipal Scientist, Commercial & Late-Stage Cell Culture Process DevelopmentSouth San Francisco, CA$159,000–$207,000 / yearSupport lifecycle management activities for commercial products, including process improvements, tech transfer validation activities, local and cross-site change management, regulatory filing updates (CBE, PAS, Ex-US expansion), and responses to health authority questions. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.
Senior Manager, Quality Control Vir Biotechnology, Inc.Senior Manager, Quality ControlSan Francisco, CA$142,500–$199,000 / yearThe Senior Manager, Technical Operations Quality Control, is responsible for executing and operationalizing QC strategy across assigned programs and external testing partners (e.g., CDMOs/CTLs) from Phase 1 through commercialization. The Senior Manager partners cross-functionally with Quality, Technical Operations, Regulatory, and Analytical Development to deliver program milestones, maintain inspection readiness, and support global regulatory submissions.
Senior Scientist, Large Molecule Characterization Denali TherapeuticsSenior Scientist, Large Molecule CharacterizationSouth San Francisco, CA$147,000–$191,000 / yearIn depth knowledge and extensive hands-on experience developing and applying mass spectrometry-based methods (Intact/reduced MS, subunit analysis, peptide mapping, N-/O-glycosylation profiling, disulfide linkage determination, LC-MS/MS analysis) for protein sequence confirmation, identification and characterization of product variants, and comparability in the context of protein therapeutics. Qualifications/Skills: Typically requires a PhD in Analytical Chemistry, Chemical Engineering, Biophysics or related scientific discipline and 3+ years of direct CMC-focused analytical development experience in protein therapeutics within the biotech/biopharma industry (MS with 8+ or BS with 10+ years' experience).
NewPrincipal Scientist, Commercial and Late-Stage Purification Process Development Denali Therapeutics IncPrincipal Scientist, Commercial and Late-Stage Purification Process DevelopmentSouth San Francisco, CA$159,000–$207,000 / yearSupport lifecycle management activities for commercial products, including process improvements, tech transfer validation activities, local and cross-site change management, regulatory filing updates (CBE, PAS, Ex-US expansion), and responses to health authority questions. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.
Associate Director, CMC Project Management ORIC Pharmaceuticals IncAssociate Director, CMC Project ManagementSouth San Francisco, CA$210,000–$240,000 / yearORIC's clinical stage product candidates include (1) rinzimetostat (ORIC-944), an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) enozertinib, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Working with functional leads (Drug Substance, Drug Product, and Analytical Department Heads), execute a robust external manufacturing strategy, including selection, onboarding, and management of CMOs/CDMOs.
Senior Scientist, Characterization Denali Therapeutics IncSenior Scientist, CharacterizationSouth San Francisco, CA$147,000–$191,000 / yearIn depth knowledge and extensive hands-on experience developing and applying mass spectrometry-based methods (Intact/reduced MS, subunit analysis, peptide mapping, N-/O-glycosylation profiling, disulfide linkage determination, LC-MS/MS analysis) for protein sequence confirmation, identification and characterization of product variants, and comparability in the context of protein therapeutics. Qualifications/Skills: Typically requires a PhD in Analytical Chemistry, Chemical Engineering, Biophysics or related scientific discipline and 3+ years of direct CMC-focused analytical development experience in protein therapeutics within the biotech/biopharma industry (MS with 8+ or BS with 10+ years' experience).
Principal Scientist, Purification Process Development Denali Therapeutics IncPrincipal Scientist, Purification Process DevelopmentSouth San Francisco, CA$159,000–$207,000 / yearDenali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients. Qualifications/Skills: Typically requires a PhD in Biology, Biochemistry, Chemical Engineering or related scientific discipline, plus 10+ years' of related work experience.
Senior Scientist Drug Product Contract Adverum Biotechnologies IncSenior Scientist Drug Product ContractRedwood City, CA$80–$90 / hourLeveraging the research capabilities of its proprietary intravitreal IVT platform, Adverum is developing durable single-administration therapies designed to be delivered in physicians offices to eliminate the need for frequent ocular injections to treat these diseases. What youll do Demonstrates technical proficiency and cross-functional collaboration with External Manufacturing, Process Development, Analytical Development, Quality Control, and other relevant stakeholders to drive improvement, consistency, and compliance for drug product manufacturing processes.
Principal Scientist, Downstream Process Development (Contract) - AW Adverum Biotechnologies IncPrincipal Scientist, Downstream Process Development (Contract) - AWRedwood City, CA$80–$90 / hourThe successful candidate will participate in late-stage activities including design and optimization of the process as needed using historical batch data and manufacturing needs; process characterization; and tech-transfer of downstream processes to support clinical and commercial manufacturing. Leveraging the research capabilities of its proprietary intravitreal (IVT) platform, Adverum is developing durable, single-administration therapies designed to be delivered in physicians' offices to eliminate the need for frequent ocular injections to treat these diseases.
Quality Manager, Peptide API & Development Hims & HersQuality Manager, Peptide API & DevelopmentMenlo Park, CaliforniaThis role will be responsible for establishing and maintaining a practical, inspection-ready quality system that supports peptide API manufacturing, laboratory controls, and a small GMP-compliant development space for formulation and sterile finished product work intended for transfer into 503A and 503B operations. Provide Quality oversight for peptide API manufacturing operations, including raw material control, in-process controls, laboratory results review, disposition support, and batch release/rejection decision-making as applicable.
Project Manager, Peptide API Operations Hims & HersProject Manager, Peptide API OperationsMenlo Park, CaliforniaCollaborate with global teams and external partners to align technical requirements, project timelines, and key deliverables while effectively managing communication across multiple time zones. This role will drive cross-functional coordination across Operations, Quality (QA/QC), and global partners to ensure successful process transfer, facility readiness, and on-time program delivery.
Senior Manager, Battery R&D Blue CurrentSenior Manager, Battery R&DHayward, CA$135,900–$193,000 / yearFree of flammable liquid electrolytes, Blue Current's fully dry, inherently safe batteries significantly reduce risks to human and environmental health while providing a higher-performance alternative to traditional lithium-ion batteries. The ideal candidate combines deep cathode and electrode expertise with strong people and program leadership, enabling effective execution, data-driven decision-making, and effective risk management.
NewPrincipal Scientist, CMC Analytical Development - Commercial Products Denali TherapeuticsPrincipal Scientist, CMC Analytical Development - Commercial ProductsSouth San Francisco, CA$159,000–$207,000 / yearAs the product transitions into routine commercial production and Denali pursues marketing applications in additional countries, we are seeking a Principal Scientist to join our Large Molecule Analytical Development Team to serve as a Commercial Analytical Lifecycle Lead. The Commercial Analytical Lifecycle Lead is expected to partner closely with peer Late Stage Analytical Development and Bioassay Development Leads responsible for driving successful analytical transfer & registration of a second-source manufacturing and QC site.