Regional Biology Lead BKFRegional Biology LeadRedwood City, CA$153,691–$187,845 / yearSupport clients in need of environmental permitting, including but not limited to Incidental Take Permits, Habitat Conservation Plan Drafting and consistency analyses, Clean Water Act 401 and 404 permits, California Coastal Commission permits, and CDFW Section 1600 permitting. In the event a recruiter or agency submits a resume or candidate without a previously signed agreement and a specific solicitation for the position or other approved engagement request for the position with BKF Engineers, BKF Engineers reserves the right to pursue and hire those candidate(s) without any financial obligation to the recruiter or agency.
Senior Machine Learning Scientist, AI for Biology & Translation (AIBT) Genentech IncSenior Machine Learning Scientist, AI for Biology & Translation (AIBT)South San Francisco, CAThe new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. Roche's Research and Early Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact.
Senior Machine Learning Scientist, Foundational ML, AI for Biology & Translation (AIBT) Genentech IncSenior Machine Learning Scientist, Foundational ML, AI for Biology & Translation (AIBT)South San Francisco, CA$147,800–$274,400 / yearThe new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. Scale frontier AI models to massive datasets working at the intersection of deep learning and engineering challenges, focusing on system design, architectural choices, and scalability, in collaboration with engineering and MLOps teams.
Executive Director, Computational Systems Biology Revolution MedicinesExecutive Director, Computational Systems BiologyRedwood City, CaliforniaThe individual will lead a team of computational biologists and bioinformaticians focused on acquisition, organization, and analysis of large multi-omics data sets, using both public and proprietary data sources, that will help inform treatment strategies and guide patient stratification for a growing pipeline of RAS(ON) and targeted oncology therapeutics. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.
Executive Director, Computational Systems Biology Revolution Medicines IncExecutive Director, Computational Systems BiologyRedwood City, CA$265,000–$331,000 / yearThe individual will lead a team of computational biologists and bioinformaticians focused on acquisition, organization, and analysis of large multi-omics data sets, using both public and proprietary data sources, that will help inform treatment strategies and guide patient stratification for a growing pipeline of RAS(ON) and targeted oncology therapeutics. The company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.
Principal Scientist, Cancer Biology General ProximityPrincipal Scientist, Cancer BiologySan Francisco, CAPre-clinical characterization and mechanistic elucidation of small-molecule drug candidatesMechanistic studies of cancer cell signaling and PTM analysisPhenotypic assay development for cancer drug discovery (low to high throughput)Small molecule drug development campaigns (hit discovery, hit validation, dose-response studies, SAR and MOA studies)Proficiency in: Managing a team of exceptional scientists and research associatesTarget/indication selectionAnimal models of cancer (GEMM, orthotopic, xenograft models), in vivo study design, and PK/PD interpretationManaging CROs for in vitro and in vivo studiesGrant writingNice to have:Experience navigating IND-enabling studies and working on teams that have successfully advanced research to the clinicExperience working at the interface of cancer biology and chemistry Familiarity or experience with PROTAC/next-gen IPM technologiesExperience with PPI techniques (e.g., BRET, APEX/BioID, AlphaScreen etc.)BenefitsStrong equity incentives. Strong experience with:Cellular and molecular biology, including cancer cell line work and associated assays, stable cell line generation (lentiviral and CRISPR-based systems), co-IP/pull-down assays, RNA-seq, global proteomics, flow cytometry, plasmid design/cloning etc.
Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity and Related) Amgen IncAssociate Director - Computational Biology (Cardiovascular, Metabolic, Obesity and Related)South San Francisco, CA$182,465–$246,865 / yearThe Computational Biology group in the Center for Technology and Innovation (CfTI) within the Precision Medicine organization at Amgen is seeking a highly motivated Computational Biologist with expertise in analyzing clinical biomarker data, including but not limited to metabolomics, genomics, transcriptomics, proteomics, spatial-omics, flow cytometry, immunoassays, and other biomarker assays. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Scientist, Mechanistic Biology General ProximityScientist, Mechanistic BiologySan Francisco, MississippiYour responsibilities will include designing and executing mechanistic studies on hit compounds, dissecting signaling pathways to map compound mechanism of action, interrogating protein-protein interactions, preparing and analyzing NGS libraries, and developing and deploying functional cell-based assays to characterize novel pharmacology. Strong experience with : Cellular and molecular biology, including extensive experience with mammalian cell line work and associated assays, stable cell line generation (lentiviral and CRISPR-based systems), co-IP/pull-down assays, RNA-seq, global proteomics, flow cytometry, plasmid design/cloning, etc.
Scientist/Sr. Scientist, Chemical Biology General ProximityScientist/Sr. Scientist, Chemical BiologySan Francisco, MississippiYour responsibilities will include: supervising synthetic efforts with our CROs, designing, performing, and analyzing in cellulo assays, designing and optimizing first-in-class bifunctional molecules, collaborating with our Drug Discovery and IP team on patent applications, providing input for mechanistic studies on lead drug molecules, and spearheading forays into new disease areas. Experience with chemical biology techniques such as mammalian cell culture and cell-based assays (e.g., cytotoxicity assays, transfections, stable cell line generation, co-immunoprecipitation), and PPI assays (e.g., BRET, APEX/BioID, AlphaScreen).
Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity And Related) Amgen Inc.Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity And Related)South San Francisco, CA$182,465–$246,865 / yearThe Computational Biology group in the Center for Technology and Innovation (CfTI) within the Precision Medicine organization at Amgen is seeking a highly motivated Computational Biologist with expertise in analyzing clinical biomarker data, including but not limited to metabolomics, genomics, transcriptomics, proteomics, spatial-omics, flow cytometry, immunoassays, and other biomarker assays. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Scientist II, Structural Biology Revolution Medicines, Inc.Scientist II, Structural BiologyRedwood City, CA$132,000–$166,000 / yearThe company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Interact with interdisciplinary teams (including chemists, computational chemists, biologists, project teams, and management) and clearly articulate structural data in a broader drug discovery context.
Developmental Biology Faculty in Otolaryngology-Head & Neck Surgery Stanford UniversityDevelopmental Biology Faculty in Otolaryngology-Head & Neck SurgeryStanford, CA$196,000–$214,000 / yearThe Department of Otolaryngology - Head & Neck Surgery at Stanford University seeks a developmental biologist (PhD or MD) with interest in neurosensory biology to join the OHNS Department as Assistant Professor, Associate Professor or Professor in the University Tenure Line (UTL), University Medical Line (UML) or Non-Tenure Line-Research (NTL-R). We are particularly interested in candidates who have a strong background in stem cell biology and experience with combining multiple approaches, such as in vitro organoid methodologies and in vivo models, to investigate the development of sensory organs of the head and neck and to understand disorders of the hearing, vestibular, and/or olfactory systems.
Scientist II, Structural Biology Revolution Medicines IncScientist II, Structural BiologyRedwood City, CA$132,000–$166,000 / yearThe company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Interact with interdisciplinary teams (including chemists, computational chemists, biologists, project teams, and management) and clearly articulate structural data in a broader drug discovery context.
Scientist II, Structural Biology Revolution MedicinesScientist II, Structural BiologyRedwood City, California$132,000–$166,000 / yearThe company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Interact with interdisciplinary teams (including chemists, computational chemists, biologists, project teams, and management) and clearly articulate structural data in a broader drug discovery context.
Vector Control Manager Alameda CountyVector Control ManagerAlameda, CAUnder direction of the Chief, Vector Control Services District, the Vector Control Manager provides supervision and guidance for the Supervising Vector Control Biologists and Senior Vector Control Biologists and Vector Control Biologists for the County Vector Control Services District; assists the Chief in the overall administration of the District; assists in managing and developing all vector control programs; provides technical expertise in the field of vector control and vector-borne disease and surveillance; consults with staff on policy and current pest management practices, and environmental related matters; performs other duties as required. Education: A Bachelorâs Degree from an accredited four-year college or university (180 quarter units or 120 semester units) in Biological Sciences, Physical Sciences, Environmental Health, Integrated Pest Management or closely related Health Sciences field is required.