Research Data Manager UCSF Medical CenterResearch Data ManagerSan Francisco, CAAs the coordinating center for the international Preclinical Design and Clinical Translation of Regimens for Tuberculosis (PReDiCTR-TB) Consortium, the laboratory integrates computational science, predictive modeling, translational pharmacology, clinical data, and quantitative decision science to support regimen selection, dose optimization, clinical trial design, and model-informed decision-making across the drug development lifecycle. The Savic Integrated Pharmacology Laboratory in the Department of Bioengineering and Therapeutic Sciences at the University of California, San Francisco (UCSF) is a global leader in model-informed drug development (MIDD) for infectious diseases and serves as an innovation hub for translational pharmacology, quantitative systems pharmacology (QSP), pharmacometrics, machine learning, artificial intelligence, and mechanistic modeling.
ML & Molecular Simulation Scientist Genesis TherapeuticsML & Molecular Simulation ScientistSan Mateo, CAOur generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. This is a role for someone who thrives at the intersection of computational science and machine learning: designing and running simulations, building ML models grounded in physical intuition, and collaborating directly with CADD and discovery teams to move molecules from hit identification to lead optimization.
ML Research Engineer, Foundation Models (Senior / Staff / Principal) Genesis TherapeuticsML Research Engineer, Foundation Models (Senior / Staff / Principal)San Mateo, CAOur generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. Bridge machine learning research and computational chemistry workflows, working closely with computational chemists, structural biologists, and medicinal chemists to ensure models translate effectively into real drug discovery programs.
Member of Technical Staff - System Engineering PhyloMember of Technical Staff - System EngineeringSouth San Francisco, CaliforniaBacked by a $13.5M seed round led by a16z, Menlo Ventures and Anthropic, and advised by Nobel Prize laureate and pioneering biologists, Phylo is building the next generation of AI systems for the life sciences. You’ll design and implement the distributed systems, compute environments, and service architecture that allow our AI agents to run reliably at scale — across cloud-native deployments and enterprise environments.
Director of Data Science and Bioinformatics NateraDirector of Data Science and BioinformaticsSan Carlos, CA$195,600–$244,450 / yearIn this role, you will build the bioinformatics capability within the Data Science development team, establish scalable AWS cloud infrastructure, and ensure the quality and reproducibility of the genomic algorithms powering our clinical products. Strong communicator who builds cross-functional alignment across Research, Engineering, and Quality teams through technical clarity, direct engagement, and data-driven reasoning.
Senior Scientist-Principal Scientist-Antibody Protein Engineering Prellis Biologics IncSenior Scientist-Principal Scientist-Antibody Protein EngineeringBerkeley, CACore activities:Reformat biologics across modalities (scFv, scFv-Fc, minibodies, Fab, VHH, Fc fusions, albumin fusions, TCRm) and assemble multispecifics (knob-in-hole, CrossMab, DVD-Ig, common LC, DARTs). We are committed to empowering our pharmaceutical partners with access to the most promising fully human antibody candidates rapidly identified from the human immune repertoire, enabling them to bring life-changing treatments to patients faster than ever before.
ML Research Engineer, Foundation Models (Senior / Staff / Principal) Genesis Molecular AIML Research Engineer, Foundation Models (Senior / Staff / Principal)San MateoOur generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. Bridge machine learning research and computational chemistry workflows , working closely with computational chemists, structural biologists, and medicinal chemists to ensure models translate effectively into real drug discovery programs.
ML & Molecular Simulation Scientist Genesis Molecular AIML & Molecular Simulation ScientistSan MateoOur generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. This is a role for someone who thrives at the intersection of computational science and machine learning: designing and running simulations, building ML models grounded in physical intuition, and collaborating directly with CADD and discovery teams to move molecules from hit identification to lead optimization.
Research Scientist Tabula BioResearch ScientistSan Francisco, CaliforniaThe core of our scientific work is the development of physics-based mathematical models of phage–bacteria interaction dynamics — how phages locate, bind to, infect, and replicate within bacterial targets at the population level — together with the large-scale numerical simulation of those models to identify and refine candidate therapies. We are looking for someone who is strong in numerical methods, large-scale simulation, and the modeling of complex dynamical systems, who likes difficult technical problems, and who wants to work on something where the connection between model quality and real-world impact is unusually direct.
ML & Molecular Simulation Scientist Genesis Molecular AI IncML & Molecular Simulation ScientistSan Mateo, CAOur generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. This is a role for someone who thrives at the intersection of computational science and machine learning: designing and running simulations, building ML models grounded in physical intuition, and collaborating directly with CADD and discovery teams to move molecules from hit identification to lead optimization.
Bioinformatics Engineer, QDI Qiagen Redwood CityBioinformatics Engineer, QDIRedwood City, California$130,000–$150,000 / yearAs a Bioinformatics Engineer in the Content Development team, you will play a critical role in maintaining and extending QIAGEN’s biomedical knowledge base by integrating new knowledge from public data sources and facilitating capture of unstructured data into existing and new semantic models, as well as leveraging our Knowledge Graph to deliver data, interpretations, and inferences to our applications and customers. Familiarity with bioinformatics tools in genome biomedical research (e.g., genomic databases, genome browsers, mutation repositories), or integrative data analysis as it relates to genetics, multiomics, cell biology, physiology and pathology.
Director Of Data Science And Bioinformatics Natera IncDirector Of Data Science And BioinformaticsSan Carlos, CA$205,000–$256,200 / yearIn this role, you will build the bioinformatics capability within the Data Science development team, establish scalable AWS cloud infrastructure, and ensure the quality and reproducibility of the genomic algorithms powering our clinical products. Strong communicator who builds cross-functional alignment across Research, Engineering, and Quality teams through technical clarity, direct engagement, and data-driven reasoning.
Director of Data Science and Bioinformatics Natera IncDirector of Data Science and BioinformaticsCA$178,200–$222,800 / yearIn this role, you will build the bioinformatics capability within the Data Science development team, establish scalable AWS cloud infrastructure, and ensure the quality and reproducibility of the genomic algorithms powering our clinical products. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other.
BIOINFORMATICS PROGR UCSF Medical CenterBIOINFORMATICS PROGRSan Francisco, CAThe scope of work will include anayzing biological datasets generated experimentally including but not limited to bulk and single cell multiomics sequencing, epigenomics data including ChIP-Seq and CUT&RUN, and imaging data including spatial transcriptomics; overlapping experimental data with publicaly available genomic and expression datasets including UK Biobank, All of Us, Heart Cell Atlas, and similar datasets. The incumbent will work closely with prinicpal investigators within the Genetic Center to design and implement analysis pipelines in several broad areas of computational biology including analysis of experimentally generated datasets in basic research, and analysis of patient-derived genomic data from UCSF patients as well as publicly available data repositories.
Bioinformatics Engineer, QDI Qiagen N.VBioinformatics Engineer, QDIRedwood City, CA$130,000–$150,000 / yearAs a Bioinformatics Engineer in the Content Development team, you will play a critical role in maintaining and extending QIAGEN's biomedical knowledge base by integrating new knowledge from public data sources and facilitating capture of unstructured data into existing and new semantic models, as well as leveraging our Knowledge Graph to deliver data, interpretations, and inferences to our applications and customers. Familiarity with bioinformatics tools in genome biomedical research (e.g., genomic databases, genome browsers, mutation repositories), or integrative data analysis as it relates to genetics, multiomics, cell biology, physiology and pathology.
Bioinformatics Engineer, Pipelines MithrlBioinformatics Engineer, PipelinesSan Francisco, CaliforniaYou will architect Nextflow and nf-core style pipelines, implement modality-specific validation and QC layers, and collaborate with the Tabular Data Team and Knowledge Curation Team to ensure downstream data harmonization, variable ID mapping, and schema alignment. Design and maintain production grade bioinformatics pipelines for a wide range of data modalities, including microarray, cell painting, WGS and WES, spatial transcriptomics, flow cytometry, ATAC-seq, and methyl-seq.
Bioinformatics Quality Engineer, QDI Qiagen Redwood CityBioinformatics Quality Engineer, QDIRedwood City, CaliforniaAs a Bioinformatics Quality Engineer in the Content Development team, you will play a critical role in maintaining and validating QIAGEN’s biomedical knowledge base and content delivered to QIAGEN’s analytics software. You will be part of a collaborative, cross-functional team of content scientists, knowledge engineers, and software engineers building powerful tools to gain insight into biomolecular data.
NewBioinformatics Production Engineer Natera IncBioinformatics Production EngineerSouth San Francisco, CA$114,400–$143,000 / yearPOSITION SUMMARY: The Bioinformatics Production Analyst performs basic data analysis to provide bioinformatics support for Horizon Carrier Screening and future platform sequencing tests, while actively participating in production pipeline improvements. PRIMARY RESPONSIBILITIES: Data Analysis & Processing: Analyze high-throughput DNA sequencing data and perform basic data analysis to support product development, validation studies, and incoming experiment analysis requests.
NewBioinformatics Quality Engineer, QDI Qiagen NVBioinformatics Quality Engineer, QDIRedwood City, CA$130,000–$160,000 / yearAs a Bioinformatics Quality Engineer in the Content Development team, you will play a critical role in maintaining and validating QIAGEN's biomedical knowledge base and content delivered to QIAGEN's analytics software. You will be part of a collaborative, cross-functional team of content scientists, knowledge engineers, and software engineers building powerful tools to gain insight into biomolecular data.
Antibody Engineering Chai Discovery IncAntibody EngineeringSan Francisco, CAYoull get exposed to a wide array of scientific problems and research methods, far beyond what one encounters working on a single drug program or within a traditional life sciences company. We are looking for exceptional antibody engineers and computational protein designers to help us evaluate, expand and apply the capabilities of our de novo antibody design models.