Biologist GlobalchannelmanagementBiologistBoston, MassachusettsBiologist needs 3 years of hands-on laboratory experience (academic or industry) with ELISAs, and automated liquid handlers. Hands-on experience with immunoassay techniques, molecular biology workflows, and laboratory automation platforms.
Cell Biologist GlobalchannelmanagementCell BiologistBoston, MassachusettsCulture and execute routine directed differentiation of human iPSCs to pancreatic islets performing drug substance assessments such as cell counts, viability, metabolite assessments. Generate clonal gene edited iPSC lines and characterize via flow cytometry, ddPCR, dPCR and qPCR.
Cell line Biologist GlobalchannelmanagementCell line BiologistBoston, MassachusettsExperience performing basic techniques in molecular biology and cell biology, such as cell culture, aseptic technique, transient transfection, ddPCR. Critically assess data generated from diverse experimental approaches in cell and molecular biology.
Vivo Pharmacology Biologist GlobalchannelmanagementVivo Pharmacology BiologistBoston, MassachusettsWork with team leads to design and execute in vivo pharmacology experiments to characterize activity, distribution, and clearance of genetic medicines in rodent models, including immunocompromised animals. Experience of small animal stereotaxic surgeries including but not limited to intracerebral (IC), intracisterna magna (ICM) and intracerebroventricular (ICV) injections in rodents will be a plus.
Tech Staff - Computational Biologist Lincoln LaboratoryTech Staff - Computational BiologistLexington, MA$145,200–$170,000 / yearThe final salary offered to a selected candidate will depend on various factors, including-but not limited to-the scope and responsibilities of the role, the candidate's experience, skills and education/training, internal equity considerations and applicable legal requirements. The Counter-WMD Systems Group at MIT Lincoln Laboratory is seeking a highly motivated and multidisciplinary biologist to support research and development efforts focused on national security challenges.
Senior / Principal Computational Biologist Flagship Pioneering, Inc.Senior / Principal Computational BiologistSomerville, MA$179,000–$236,000 / yearAs the computational biology lead embedded in our cross-functional drug discovery programs, you will collaborate closely with world-class computational biologists, machine learning scientists, experimental biologists, chemists, clinicians, and technologists to co-develop hypotheses from cell atlases and advance programs from biological model development through hit identification and lead optimization. Use transcriptomic data across the program lifecycle to develop disease hypothesis, evaluate in vitro and in vivo models, analyze perturbation effects, validate hits and leads, and deconvolute targets and mechanism of actions.
Computational Scientist, Assay Development Manifold BioComputational Scientist, Assay DevelopmentBoston, MA$118,000–$138,000 / yearManifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively multiplexed in vivo screening to unlock tissue-targeted medicines and organism-scale models of living systems. Using proprietary molecular barcoding technology, we screen hundreds of thousands of protein designs simultaneously in living systems, producing in vivo-validated datasets at a scale no one else can match.
Computational Scientist, Protein Engineering Manifold Bio IncComputational Scientist, Protein EngineeringBoston, MA$118,000–$138,000 / yearManifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively multiplexed in vivo screening to unlock tissue-targeted medicines and organism-scale models of living systems. Using proprietary molecular barcoding technology, we screen hundreds of thousands of protein designs simultaneously in living systems, producing in vivo-validated datasets at a scale no one else can match.
Data Scientist - Computational Biology Penfield Search PartnersData Scientist - Computational BiologyWaltham, MAThe ideal candidate has hands-on experience with RNA sequencing data, strong computational biology expertise, and enjoys collaborating closely with experimental scientists to generate biological insights that advance therapeutic discovery. This individual will support drug discovery research by processing, analyzing, visualizing, and interpreting next-generation sequencing (NGS) datasets, with a strong emphasis on transcriptomics and long-read sequencing technologies.
Senior Scientist, Computational Biology Tessera Therapeutics IncSenior Scientist, Computational BiologySomerville, MA$141,000–$171,000 / yearHis group supports drug candidate programs through genotoxicity risk assessment, develops computational approaches to study gene writing biology, and builds scalable data and analysis infrastructure to support molecular assay design and knowledge mining. Broad knowledge of genome editing technologies and associated off-target discovery assays (i.e. WGS; targeted sequencing; GUIDE-seq, Digenome-seq discovery / verification; large and small structural variations and translation effects; NGS QC).
Senior / Principal Scientist, Structural Biology - Target Druggability & Structure-Based Drug Design Schrodinger IncSenior / Principal Scientist, Structural Biology - Target Druggability & Structure-Based Drug DesignFramingham, MA$135,000–$190,000 / yearAs a member of our Structural Biology and Target Enablement team in our Therapeutics Group, you'll partner with Molecular Pharmacologists, Biologists, Medicinal Chemists, and Computational Chemists to define target tractability strategies, identify and validate novel and cryptic binding sites, and design and supervise experimental campaigns to solve unprecedented structures that unlock previously intractable targets. Lead experimental structural biology efforts on active target enablement and drug discovery programs, managing work at external CROs, collaborating with our internal Structural Biology team, and/or directly performing hands-on experiments at our internal laboratory.
Senior Director, In Vitro Biology & Molecular Pharmacology Schrodinger IncSenior Director, In Vitro Biology & Molecular PharmacologyFramingham, MA$230,000–$300,000 / yearSpearhead the organization wide hit finding strategy, collaborating across functions to design and execute screening campaigns across DEL, fragment-based, HTS/MTS, and chemoproteomic platforms, focusing on novel methods for undrugged targets. As a senior member of our Therapeutics Group, you'll direct strategy and execution across a pipeline of small molecule drug discovery programs, with a particular focus on undrugged targets, novel modalities, and novel hit finding approaches.
Senior Scientist, Computational Biology Tessera TherapeuticsSenior Scientist, Computational BiologySomerville, MA$141,000–$171,000 / yearHis group supports drug candidate programs through genotoxicity risk assessment, develops computational approaches to study gene writing biology, and builds scalable data and analysis infrastructure to support molecular assay design and knowledge mining. Broad knowledge of genome editing technologies and associated off-target discovery assays (i.e. WGS; targeted sequencing; GUIDE-seq, Digenome-seq discovery / verification; large and small structural variations and translation effects; NGS QC).
Biology Contractor StratAcuity Staffing Partners IncBiology ContractorCambridge, MA$40–$55 / hourIn terms of professional development, Everforth Apex hosts an on-demand training program, provides access to certification prep and a library of technical and leadership courses/books/seminars once you have 6+ months of tenure, and certification discounts and other perks to associations that include CompTIA and IIBA. The ideal candidate will bring strong expertise in cell-based assay development, mammalian cell culture, and molecular biology techniques, along with a demonstrated ability to generate high-quality data in a collaborative, fast-paced research environment.
Principal Scientist, Computational Biology Bristol-Myers Squibb CoPrincipal Scientist, Computational BiologyMARemote$166,770–$202,086 / yearIPS conducts applied computational research in areas that include genomic, structural and molecular informatics, computational and systems biology, patient selection and translational biomarker research, and broader fields including knowledge science, epidemiology and machine learning-across the full lifecycle of drug discovery and development and across all therapeutic areas at BMS. Hands on experience analyzing and integrating high-dimensional molecular datasets such as multi-omics (RNA-seq, ATAC-seq, proteomics, ChIP-seq/CUT&RUN), single cell profiling (CITE-seq, scATAC-seq, perturb-seq) and/or spatial profiling to derive novel biological insights.
Data Scientist Contractor, Computational Biology CAMP4 Therapeutics CorpData Scientist Contractor, Computational BiologyCambridge, MAKey Responsibilities: Process, analyze, visualize, and interpret next-generation sequencing (NGS) datasets, with an emphasis on bulk RNA-seq, scRNAseq, and long-read RNA sequencing, including Nanopore and PacBio sequencing data. CAMP4 is seeking a Data Science Contractor for a 6-month temporary contract assignment, specializing in Computational Biology, Bioinformatics, or Systems Biology, to support the processing, analysis, visualization, and interpretation of next-generation sequencing datasets.
Scientist I Disease Modeling and Mechanism Disease Biology & Pharmacology Astellas Pharma IncScientist I Disease Modeling and Mechanism Disease Biology & PharmacologyCambridge, MAResponsible for design, execution, and analysis of non-clinical biological studies necessary to validate novel therapeutic concepts and modalities of anti-cancer drugs leveraging cutting-edge science and assay technologies independently. This is a biologist position developing anti-cancer drugs, including antibody-drug conjugates (ADCs), multi-specific antibodies or engineered small molecules in collaboration with discovery and program teams.
Director, Computational Biology Ionis Pharmaceuticals IncDirector, Computational BiologyBoston, MA$157,542–$206,759 / yearWith multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals. Well-suited candidates will have a systems level approach to understanding biology that harmonizes multiple interacting functional inputs including transcriptional regulation, protein function and larger order (cellular and tissue) biochemical relationships.
Scientist II / Senior Scientist, Computational Biology Flagship Pioneering IncScientist II / Senior Scientist, Computational BiologySomerville, MA$130,000–$180,000 / yearCollaborating closely with world-class computational biologists, machine learning scientists, experimental biologists, chemists, clinicians, and technologists, you'll help co-develop hypotheses, build proprietary data assets, and advance exploratory drug programs. Present your results in an interdisciplinary team of biologists, chemists, clinicians, technologists, and other machine learning colleagues in meetings covering cross-functional project teams, functional teams, to whole company and management meetings.
Postdoctoral Research Fellow - Computational Functional Genomics - Gillani Lab Dana-Farber Cancer Institute IncPostdoctoral Research Fellow - Computational Functional Genomics - Gillani LabBOSTON, MA$72,000–$76,385 / yearThey will develop and support data processing and analysis tools, create new algorithms for focused research questions in bulk and single cell tumor analysis, integrate tools and databases into existing high-throughput pipelines, and drive projects to completion and publication. This Post-Doctoral Computational Biologist will also help with the generation of tools needed for manipulating and preparing data for display; transferring data to external collaborators and data repositories; and will also help maintain, support, and document shared tools, code, and data sets.