Product Marketing Manager, Globus University of ChicagoProduct Marketing Manager, GlobusChicago, IL$150,000–$180,000 / yearSuccess in this role will be demonstrated by: delivering a refreshed messaging framework covering target personas such as researchers, system administrators, and application developers; authoring high-quality content assets (case studies, whitepapers, or solution briefs) with minimal revision cycles; supporting product feature launches end-to-end, from messaging through collateral to post-launch metrics; managing multi-channel marketing and communications programs; and establishing a repeatable market intelligence process that informs our sales and marketing efforts. Core features are free for non-profit researchers, and the Globus service is sustained through institutional subscriptions that unlock advanced features for organizations needing greater control, compliance support, and deeper integration with their research computing environment.
Account Manager - State Farm Agent Team Member Rick Weissenhofer - State Farm AgentAccount Manager - State Farm Agent Team MemberOswego, ILFull timeAs Account Manager - State Farm Agent Team Member for Rick Weissenhofer - State Farm Agent, you are vital to our daily business operations and customers’ success. State Farm has always been a big part of my life - my dad is a State Farm agent, I interned with State Farm Corporate, and later worked for another agent before opening my own agency.
General Manager Cast Stone Precast Manufacturing STONEGeneral Manager Cast Stone Precast Manufacturingchicago, ILFull timeAs a manager, you'll be responsible for cultivating new leads, setting up distributors and embracing a multifaceted role in a manufacturing business. We work with the top designers, architects and builders nationally supplying them with mantels, bathtubs, sinks and other architectural products.
General Manager STONEGeneral Managerchicago, ILFull timeAs a manager, you'll be responsible for cultivating new leads, setting up distributors and embracing a multifaceted role in a manufacturing business. We work with the top designers, architects and builders nationally supplying them with mantels, bathtubs, sinks and other architectural products.
Senior Preconstruction Manager Pyramid, IncSenior Preconstruction ManagerChicago, IL$140,000–$180,000 / yearFull timeKey Requirements and Technology Experience: Must Have Skills: Preconstruction and estimating leadership, 10 years commercial construction experience, creating cost models, estimates, reviewing and advising staff estimates Bachelor’s degree in Engineering, Architecture or Construction Management Minimum 10 years commercial construction experience including 5 years in preconstruction/estimating. The Senior Preconstruction Manager is responsible for creating cost models, estimates, reviewing and advising staff estimates, training, value analysis, and sales/marketing.
Manager STONEManagerchicago, ILFull timeAs a manager, you'll be responsible for cultivating new leads, setting up distributors and embracing a multifaceted role in a manufacturing business. We work with the top designers, architects and builders nationally supplying them with mantels, bathtubs, sinks and other architectural products.
Strategic Partnerships Account Manager, Databricks West Monroe Partners, LLCStrategic Partnerships Account Manager, DatabricksChicago, IL$137,300–$161,500 / yearWorking across executive leadership, client teams, marketing, sales, and technical practitioners, you''ll help maximize the value of our strategic alliances while building scalable operating processes that support long-term growth. As we continue to invest in our strategic technology ecosystem, we''re looking for a Strategic Partner Account Manager to help scale and operationalize our most important alliances, including Databricks, Microsoft, and AWS.
Account Manager, Chain Salons Wella International Operations Switzerland SarlAccount Manager, Chain SalonsIllinois, ILThe role will have direct selling & account management responsibilities and will partner with Trade Marketing, Brand Marketing, Finance, Analytics, Demand Planning and Education teams to develop and execute business plans that meet or exceed targets. Actual salaries will vary and may be above or below the range based on various factors including but not limited to location, experience, skills and in comparison to internal incumbents currently in similar roles-pay Range: 91K-120K salary per year plus bonus.
Senior Product Manager Vivid Seats IncSenior Product ManagerChicago, IL$115,000–$150,000 / yearProactively identify and size new opportunities across the web journey, including acquisition, discovery, event pages, landing experiences, personalization, checkout entry points, and customer engagement. Drive improvements across the web customer journey, including event discovery, search, event pages, ticket selection, checkout entry points, landing pages, and other key conversion surfaces.
Principal Payment Product Readiness Manager Capital One Financial CorpPrincipal Payment Product Readiness ManagerChicago, IL$138,100–$157,700 / yearPrincipal Payment Product Readiness Manager's work will support a variety of internal and external clients, including client-facing teams, issuers, merchants, acquirers, digital enablers and payment providers in a global environment. Candidates hired to work in other locations will be subject to the pay range associated with that location, and the actual annualized salary amount offered to any candidate at the time of hire will be reflected solely in the candidate's offer letter.
Senior Client Account Manager, Large Customer Sales Restaurants and Drinks Reddit IncSenior Client Account Manager, Large Customer Sales Restaurants and DrinksChicago, IL$135,100–$189,200 / yearProactively manage and deepen relationships with existing advertising partners, both with agencies and directly with Fortune 500 clients to drive year-on-year Reddit revenue growth. This person will closely collaborate with Client Partner on campaign execution and optimizations to help agencies and advertisers achieve their marketing objectives on the fast-growing Reddit platform.
Technical Customer Success Manager Scion Staffing IncTechnical Customer Success ManagerChicago, ILThrough our innovative team building and recruiting solutions, we bridge the gap in executive leadership searches, direct hire recruiting, interim leadership placement, and temporary professional staffing. 5+ years' experience in Customer Success, Account Management, Consulting, or Client Services within SaaS, Marketing Technology, Retail Technology, Loyalty, CRM, or Customer Data platforms.
NewMarketing Manager (Lead Generation) Green Office PartnerMarketing Manager (Lead Generation)Chicago, ILWe specialize in developing document workflow solutions and managed print services that increase security, control costs, and improve the efficiency of our partners. We have been ranked #1 best places to work in Chicago by the Chicago Sun-Times, 2024 & 2025 and Crain's Chicago Business for 2023, 2024 & 2025, in addition to the.
Category Manager Pregis LLCCategory ManagerChicago, IL$159,000–$191,000 / yearCategory Manager Job Profile: The Category Manager will have ownership for Air Systems, working collaboratively with Sales, Marketing, Manufacturing and Finance leaders to develop and implement strategies to set and successfully achieve financial targets. Develop overall market strategy for product line and work collaboratively with Sales, Marketing and Operations leaders to develop functional strategies to support the achievement of short-term and long-term product line objectives.
Senior Client Account Manager, Large Customer Sales Pharma Reddit IncSenior Client Account Manager, Large Customer Sales PharmaChicago, IL$135,100–$189,200 / yearProactively manage and deepen relationships with existing advertising partners, both with agencies and directly with Fortune 500 clients to drive year-on-year Reddit revenue growth. This person will closely collaborate with Client Partner on campaign execution and optimizations to help agencies and advertisers achieve their marketing objectives on the fast-growing Reddit platform.
Account Manager Rakuten Group, Inc.Account ManagerChicago, IL$52,407–$89,316 / yearWith access to Rakuten's diverse media properties and audiences, combined with an award-winning performance network and proprietary consumer research, Rakuten Advertising creates the right conditions to reach new customers and sustain long-lasting loyalty. Headquartered in San Mateo, California with more than 4,000 employees worldwide, the Rakuten International business portfolio includes market leaders in e-commerce, digital marketing, advertising, communications and entertainment.
Senior Manager, Partnership Sales | Northwestern University Legends GlobalSenior Manager, Partnership Sales | Northwestern UniversityEvanston, Illinois$90,000–$100,000 / yearDelivering for the world’s largest and most complex projects, Legends Global Partnerships experts deliver innovative solutions to create integrated and meaningful partnerships, connecting our partners with the world’s premier and emerging brands in a transformational way. The Senior Manager of Partnership Sales will identify emerging sponsorship categories, build relationships across a variety of industries, generate sales leads through networking and research, conduct client presentations, and negotiate high-value contracts to meet and exceed annual revenue goals.
Manager, Strategic Solutions - Retail Sirius XMManager, Strategic Solutions - RetailChicago, Illinois$75,000–$120,000 / yearAs the combined advertising revenue organization of Sirius XM Holdings Inc., SiriusXM Media spans across leading owned and operated audio platforms Pandora and SiriusXM; innovative ad tech solutions powered by AdsWizz; sonic creative consultancy Studio Resonate; and an extended content network featuring exclusive monetization agreements with Audiochuck, NBCUniversal, SoundCloud, and many more. SiriusXM and its brands (Pandora, SiriusXM Media, AdsWizz, Simplecast, and SiriusXM Connect) are leading a new era of audio entertainment and services by delivering the most compelling subscription and ad-supported audio entertainment experience for listeners -- in the car, at home, and anywhere on the go with connected devices.
Senior Enterprise Account Manager, Strategic Partnerships Wonder GroupSenior Enterprise Account Manager, Strategic PartnershipsChicago, Illinois$92,800–$116,000 / yearAs a leading U.S. ordering and delivery marketplace, we feature over 415,000 merchants in more than 4,000 cities, creating the ultimate food experience by elevating online ordering through innovative restaurant technology, easy-to-use platforms, and an improved delivery experience. The Senior Enterprise Account Manager, Strategic Partnerships is a high-impact, revenue-driving role responsible for managing and growing Grubhub’s most valuable enterprise-level brand and merchant portfolios.
Senior Enterprise Account Manager, Strategic Partnerships Grubhub HoldingsSenior Enterprise Account Manager, Strategic PartnershipsChicago, Illinois$92,800–$116,000 / yearAs a leading U.S. ordering and delivery marketplace, we feature over 415,000 merchants in more than 4,000 cities, creating the ultimate food experience by elevating online ordering through innovative restaurant technology, easy-to-use platforms, and an improved delivery experience. The Senior Enterprise Account Manager, Strategic Partnerships is a high-impact, revenue-driving role responsible for managing and growing Grubhub’s most valuable enterprise-level brand and merchant portfolios.
Ecommerce Manager Crescent Foods Premium All Natural Halal Hand-Cut ProductsEcommerce ManagerChicago, IllinoisUtilize graphic design tools including adobe illustrator, adobe photoshop, and canva to create supplemental content for ecommerce platforms including but not limited to promotional banners, mock product flat lays, and general marketing collateral. While performing the duties of this job, the employee frequently is required to stand and talk or hear; use hands and fingers to handle, feel, or operate objects, tools, or controls and reach with hands and arms.
Website Operations & Optimization Sr Manager FREEMANWebsite Operations & Optimization Sr ManagerChicago, IL$115,000–$135,000 / yearServe as the primary intake point for web publishing requests across all TFC brand teams, including new landing pages — managing prioritization and expectation-setting — and present performance updates, SEO roadmaps, and visibility findings to marketing leadership on a regular cadence. + Own the publishing lifecycle across four TFC brand web properties (thefreemancompany.com, wearesparks.com, studioblueav.com, 3dexhibits.com) — receiving content from brand and marketing stakeholders and getting it live, well-structured, and optimized.
Director Of Marketing SangomaDirector Of MarketingChicago, ILWe are seeking a strategic and results-driven Director of Marketing to lead demand generation, channel marketing, marketing operations, events, public relations, and brand initiatives that drive pipeline growth and revenue across both direct and indirect sales channels. Sangoma is a global leader in business communications, delivering Unified Communications as a Service (UCaaS), Contact Center as a Service (CCaaS), Communications Platform as a Service (CPaaS), Managed Connectivity, and AI-powered communications solutions.
Regional Activation Manager Green Thumb Industries (GTI)Regional Activation ManagerChicago, IL$60,000–$75,000 / yearThe Regional Activation Manager will coordinate and execute regionally and nationally led marketing programs, initiatives, and events for both sides of the business, consumer packaged goods and retail, for both RISE and external dispensary accounts, all while maintaining a RISE-first concept. Ensure that any centrally and regionally-led promotions and product/strain launches are fully executed at the store level including but not limited to displays, in-stock product, signage, employee swag, employee education.
Director, Marketing SmithBucklinDirector, MarketingChicago, IL$160,000–$180,000 / yearThis leader will shape and execute integrated marketing strategies for both Smithbucklin and 360 Live Media that grow brand visibility, generate qualified leads, strengthen prospect engagement, and support business development through measurable, data-informed marketing programs. The Director, Marketing will lead a small team that includes content marketing, digital and campaign specialists, ensuring that content, digital and paid programs work together to drive awareness and qualified demand across Smithbucklin and 360 Live Media.
Director, Marketing SmithBucklin CorporationDirector, MarketingChicago, IL$160,000–$180,000 / yearThis leader will shape and execute integrated marketing strategies for both Smithbucklin and 360 Live Media that grow brand visibility, generate qualified leads, strengthen prospect engagement, and support business development through measurable, data-informed marketing programs. The Director, Marketing will lead a small team that includes content marketing, digital and campaign specialists, ensuring that content, digital and paid programs work together to drive awareness and qualified demand across Smithbucklin and 360 Live Media.
Marketing Technology & Automation Specialist - Aurora, IL Mitutoyo AmericaMarketing Technology & Automation Specialist - Aurora, ILAurora, IllinoisIn this role, you will be responsible for managing and optimizing our marketing technology ecosystem, including HubSpot and related business systems, while helping improve customer engagement, lead management, marketing performance, and operational efficiency. You’ll have the opportunity to work with modern marketing technologies, drive meaningful business impact, collaborate across departments, and help shape the future of our marketing operations.
Sr Mgr, Content Strategy and Integrated Campaigns GGP ServicesSr Mgr, Content Strategy and Integrated CampaignsChicago, Illinois$95,000–$125,000 / yearThis role sits at the intersection of content strategy, campaign execution, and marketing performance — translating business objectives into scalable, customer-centric initiatives while helping evolve GGP's B2C content approach and improving the tools, workflows, and processes that enable effective marketing at scale. The Senior Manager, Content Strategy & Integrated Campaigns leads the development, execution, and performance analysis of integrated consumer marketing campaigns and content programs that drive awareness, engagement, traffic, and sales across GGP's portfolio of retail properties.
Marketing Manager OptiverMarketing ManagerChicago, IllinoisAs a Marketing Manager, your key responsibilities include: Lead initiatives for priority audiences in the US, including developing marketing plans tailored to specific markets, audiences, hiring needs and SEO opportunities. Own Optiver's organic social strategy, leading content planning, channel management, content creation, and performance optimization while collaborating across the global marketing team to scale execution and maximize discoverability.
Senior Sales Manager (Mission Critical Services) WESCOSenior Sales Manager (Mission Critical Services)Chicago, ILRemoteAs a Senior Manager – Sales, you will provide strategic direction and progressive leadership to achieve sales and profit goals within multiple locations or a largescale location with sales revenue above $50M or significant complexities. As a Senior Sales Manager to lead customer-facing initiatives that support data center construction programs through tailored project support and material management solutions.
Brand & Product Manager Dr. Oetker Canada LtdBrand & Product ManagerNaperville, ILDevelop and execute annual and long-range brand and product business plans with a total P&L approach encompassing both commercial and operational opportunities to manage objectives, growth and profitability for categories and products. The base pay offered to the successful candidate will be reviewed and determined based on a variety of factors, including relevant skills, experience, business needs, geographical location, and internal equity.
NewLeasing Manager RPM LivingLeasing ManagerSkokie, IllinoisFull timePosition Summary: The Leasing Manager is responsible for effectively leading the leasing team and accomplishing effective leasing, marketing, and positive relations of an apartment community. Manage lease renewals, send renewal notices, handle move-outs based on lease terms, apply fees when necessary, and keep property management software updated with move-in/out and renewal data.
Sr Associate Brand Manager SunstarSr Associate Brand ManagerSchaumburg, IllinoisThis role will serve as the analytical and strategic backbone of the brand team, blending rigorous data analysis, commercial strategy, and crossâfunctional leadership to drive brand growth across both consumer and dental professional markets. The Senior Associate Brand Manager is responsible for driving brand performance, leading key marketing initiatives, and translating consumer, category, and competitive insights into actionable brand plans.
Manager, Meetings Institute of Food TechnologistsManager, MeetingsChicago, IL$85,000–$100,000 / yearReporting to the Director, Event Operations, the Manager, Event Operations is responsible for assisting with delivering on the successful logistical operations of IFT events and meetings, including Board of Directors meetings and the IFT FIRST Annual Event and Expo. IFT convenes professionals from around the world – from producers and product developers to innovators and researchers across food, nutrition, and public health – with a shared mission to help create a global food supply that is sustainable, safe, nutritious, and accessible to all.
Senior Account Manager DeanHoustonSenior Account ManagerOrland Park, IL$80,000–$95,000 / yearAs a Senior Account Manager, you'll develop relationships, lead marketing strategy, guide marketing initiatives, and uncover new opportunities to drive client success. Collaborate with our talented creative, digital, strategy, and technical teams to deliver meaningful business outcomes.
Digital Content & AI Automation Manager Okta IncDigital Content & AI Automation ManagerChicago, IL$114,000–$157,300 / yearClassification of protected categories is as follows: A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability. An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.
Sr. Field Sales Operations Manager Sprinklr IncSr. Field Sales Operations ManagerIL$146,000–$244,000 / yearSprinklr's unified platform provides powerful solutions for every customer-facing team - spanning social media management, marketing, advertising, customer feedback, and omnichannel contact center management - enabling enterprises to unify data, break down silos, and act on real-time insights. While Unified Customer Experience Management (Unified-CXM) as a category is just getting started, we are well on our way to creating a no-compromise, unified approach to better customer experiences for the world's leading enterprise brands.
Senior Manager, Insights and Analytics Zeta GlobalSenior Manager, Insights and AnalyticsChicago, ILRemote$125,000–$145,000 / yearZeta Global (NYSE: ZETA) is the AI-Powered Marketing Cloud that leverages advanced artificial intelligence (AI) and trillions of consumer signals to make it easier for marketers to acquire, grow, and retain customers more efficiently. Through the Zeta Marketing Platform (ZMP), our vision is to make sophisticated marketing simple by unifying identity, intelligence, and omnichannel activation into a single platform – powered by one of the industry's largest proprietary databases and AI.
Senior Customer Success Manager Zeta GlobalSenior Customer Success ManagerChicago, IL$75,000–$90,000 / yearZeta Global (NYSE: ZETA) is the AI-Powered Marketing Cloud that leverages advanced artificial intelligence (AI) and trillions of consumer signals to make it easier for marketers to acquire, grow, and retain customers more efficiently. You will also surface and drive upsell and cross-sell opportunities, develop tailored growth ideas for each client's business, and partner with Client Success Leadership on long‑term expansion strategies. . .
Demand Generation Manager NextpointDemand Generation ManagerChicago, IllinoisAs Demand Generation Manager, you'll own the demand generation function from strategy through execution, running multichannel campaigns that generate qualified leads and build pipeline in close partnership with sales. Nextpoint builds transformative software and services for the legal industry, making eDiscovery, case management, and litigation prep simple, fluid, and affordable for law firms of all sizes.
Account Manager Ignite VisibilityAccount ManagerChicago, IllinoisRemote4+ years experience as an Account Manager, Key Account Manager, or Account Executive in a digital marketing advertising agency supporting franchise clients. Coach production teams through pre-call syncs, on-call feedback, post-call syncs, and consistent identification of growth opportunities for the entire account team.
Sr. Director, Tradeshows - Enterprise Marketing Vizient IncSr. Director, Tradeshows - Enterprise MarketingChicago, IL$135,200–$236,600 / yearExperience leading enterprise-level tradeshow, event marketing and experiential marketing, Demonstrated success developing event strategies that support brand awareness, client engagement, demand generation, and commercial growth. You will collaborate with cross-functional stakeholders, manage event operations and resources, and provide leadership that enhances Vizient's market presence, client engagement, and commercial outcomes.
Manager, Technical Service American Water Resources AssociationManager, Technical ServiceNaperville, ILRemote$126,000–$163,000 / yearWe supply global customers with eucalyptus and softwood pulps in end use segments such as tissue, specialty, packaging and graphic papers and board, through our own sales and service networks close to customers in the APAC region, Europe and Americas. We deliver renewable and responsible solutions and innovate for a future beyond fossils across six business areas: UPM Fibres, UPM Energy, UPM Raflatac, UPM Specialty Papers, UPM Communication Papers and UPM Plywood.
Territory Manager Fortune Brands Innovations IncTerritory ManagerChicago, IL$70,000–$95,000 / yearWhat you will be doing: Under the direction and supervision of the Regional Manager, sells, services and gains a complete understanding of wholesalers, new work plumbing contractors, repair and remodel contractors, kitchen and bath dealers, architects, engineers and home builders. Develops and maintains positive relationships to support wholesale and builder market activity with Territory Managers, Strategic Account Managers, Senior Business Development Managers, Business Development Managers and Regional Managers.
Assistant Store Manager Ross Stores IncAssistant Store ManagerSchaumburg, IL$18.50–$28.36 / hourIn addition, all Full-Time Associates, including FT Retail Associate, Area Supervisor, Assistant Store Manager and Store Manager, are eligible for extended benefits offered including Medical/Dental/Vision Health Insurance, Legal Insurance, Vacation Buy, Flexible Spending Account, Health Savings Account, Life/ADD Insurance, Long- Term Disability, Enhanced Maternity and Parental Leave Benefit, Vacation Pay accrued at a rate of 10 days/year after eligibility commences, 9 Personal and Company Holidays. Understands and complies with the Loss Prevention Awareness Program and is responsible for Store Loss Prevention which includes maintaining a large Customer service presence on the sales floor, Customer and Associate engagement and heightened Loss Prevention awareness.
Community Manager Roscoe Property ManagementCommunity ManagerSkokie, ILManage the client/owner relationship by meeting with the owners, conducting property tours, providing updates, and responding to owner requests as needed to maintain a positive working relationship. Analyze and interpret market and economic trends and partner with marketing to implement short- and long-range leasing strategies to achieve occupancy and revenue goals.
Branch Manager, Bilingual CURO Group Holdings CorpBranch Manager, BilingualAurora, IL$61,500–$88,500 / yearOther company perks include access to the Employee Assistance Program, Emergency Relief Fund, Diversity and Inclusion Council, Tuition Reimbursement, Leadership Development Programs, and potential to earn through the Monthly Bonus Program. Key Words: Customer Service, Loans, Financial Services, Lending, Management, Retail, Office, Bank Teller, Sales, Collections, Leadership.
Store Manager Ross Stores IncStore ManagerHomewood, IL$59,682–$93,254 / yearIn addition, all Full-Time Associates, including FT Retail Associate, Area Supervisor, Assistant Store Manager and Store Manager, are eligible for extended benefits offered including Medical/Dental/Vision Health Insurance, Legal Insurance, Vacation Buy, Flexible Spending Account, Health Savings Account, Life/ADD Insurance, Long- Term Disability, Enhanced Maternity and Parental Leave Benefit, Vacation Pay accrued at a rate of 15 days/year, 9 Personal and Company Holidays. Understands and complies with the Loss Prevention Awareness Program and is responsible for Store Loss Prevention which includes maintaining a large Customer service presence on the sales floor, Customer and Associate engagement and heightened Loss Prevention awareness.
Category Development Manager E. & J. Gallo WineryCategory Development ManagerChicago, IL$93,800–$140,600 / yearMasters degree plus 2 years of category development or sales experience reflecting increasing levels of responsibility; OR Bachelors degree in Marketing, Advertising, Journalism, Business, Economics, or Supply Chain plus 3 years of sales or category development experience reflecting increasing levels of responsibility; OR Bachelors degree plus 4 years of category development or sales experience reflecting increasing levels of responsibility; OR High school diploma or Stateissued equivalency certificate plus 7 years of category development or sales experience reflecting increasing levels of responsibility. Bachelors degree plus 4 years of Gallo winery or distributor sales or category development experience to include a prior rotation as a Market Development Manager, Market Development Manager Sr, Spirits Development Specialist, or Account Manager 1; OR Bachelors degree plus 5 years of external alcohol sales experience to include category development experience.
Territory Manager, Interventional Pain - Chicago, IL Avanos Medical IncTerritory Manager, Interventional Pain - Chicago, ILChicago, ILRemote$70,000–$130,000 / yearHere at Avanos Medical, we passionately believe in three things: Making a difference in our products, services and offers, never ceasing to fight for groundbreaking solutions in everything we do; Making a difference in how we work and collaborate, constantly nurturing our nimble culture of innovation; Having an impact on the healthcare challenges we all face, and the lives of people and communities around the world. This includes both Capital purchases, as well as consumable product line that includes nerve ablation needles, radiofrequency ablation (rhizotomy) products, and other products providing solutions in the of treatment for pain.