Key responsibilities:Design and execute formulation screening strategies for large-molecule therapeutics, with emphasis on mAbs and related biologic modalitiesLead studies to identify stable formulations and communicate results to cross-functional R&D teamsManage team resources, timelines, and deliverables with a strong customer-focused mindsetProvide leadership, mentorship, and direction to team members as the functional managerPromote a safe, inclusive, and collaborative environment while engaging stakeholders across biologics discovery and technical developmentPartner with CMC teams to advance clinical candidates, finalize clinical formulations, and support drug product process developmentDevelop stabilization strategies for liquid, frozen, and lyophilized drug product formats for clinical developmentApply and interpret biophysical and analytical methods, including DSC, DLS, UV-Vis, turbidity, subvisible particle analysis, viscosity, SEC, and HICWork with automation teams to implement high-throughput formulation screening and physicochemical characterization across discovery, optimization, and early developmentOperate analytical instrumentation, analyze data, maintain ELN documentation, and author technical reportsContribute to data interpretation, scientific presentations, and cross-functional discussions within the global BRC communityEssential Requirements: PhD in biochemistry, biotechnology, chemistry, or a related field with 2+ years of relevant industry experienceProven experience leading, coaching, and developing scientific teamsHands-on expertise in protein formulations and assessment of biophysical properties of the molecule (e.g., DLS, Viscosity, Thermal and colloidal stability)Strong background in developing strategies for formulations for large-molecule therapeutics, with understanding of early-stage development workflowsExperience designing and executing preformulation studies and interpreting stability-indicating assays (e.g., SEC, CE, charge variants, MS)Demonstrated problem-solving skills, scientific curiosity, and ability to work independentlyExcellent communication, organizational, and multitasking skillsDesirable Requirements: Knowledge of viral vector-based gene therapy (AAV, LVV) formulation and characterizationFamiliarity with DoE tools (e.g., JMP) for high-throughput experimental designExperience working with automated liquid handling systemsCompensation and Benefits:The salary for this position is expected to range between $108,500 and $201,500 per year for Principal Scientist I, and between $119,700 and $222,300 per year for Principal Scientist II. Internal Job Title: Principal Scientist I/IIPosition Location: Cambridge, MA, onsiteJob descriptionThe Biologics Center at Novartis Biomedical Research (BRC) is seeking a highly motivated leader and experienced scientist in biologics formulation to join the Analytics, Bioanalytic, and Formulation (ABF) unit.