Protein Sciences Research Scientist Vertex Pharmaceuticals IncorporatedProtein Sciences Research ScientistSeattle, WAFull timeStrong hands-on experience with protein capture and polishing methods using resins such as MabSelect SuRe, MabSelect PrismA, Capto L, Capto DEAE, Capto Q, and Capto S. Proficiency with Waters HPLC/UPLC systems and Empower software, including SEC, HIC, IEX, and reversed-phase methods. The ideal candidate will bring strong expertise in protein purification, protein analytics, and protein-protein interaction characterization, and will help advance platform capabilities through innovative approaches in analytical characterization and biologics developability assessment.
Principal Scientist, AI Protein Sciences (Discovery Platforms & Automation) SystimmunePrincipal Scientist, AI Protein Sciences (Discovery Platforms & Automation)Redmond, WAFull timeThis position is ideal for a scientist who has experience building or significantly expanding experimental platforms and wants to take technical ownership of automation strategy, technology selection, workflow architecture, and scientific execution. This role will focus on building scalable capabilities in cell-free protein expression, purification, high-throughput binding characterization, sample handling and data analysis through the integration of AI, laboratory automation and robotics.
Senior Research Associate/Associate Scientist, Protein Engineering Systimmune IncSenior Research Associate/Associate Scientist, Protein EngineeringRedmond, WA$60,000–$85,000 / yearThe successful candidate will work closely with experienced scientists to execute and optimize protein purification workflows, support transient mammalian expression, and perform analytical characterization and developability assessments. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs).
Research Associate/Senior Research Associate, Protein Engineering Systimmune IncResearch Associate/Senior Research Associate, Protein EngineeringRedmond, WA$60,000–$85,000 / yearThe ideal candidate will be a quick learner with a broad experience set with direct expertise in a display technology and/or an adjacent field including but not limited to high throughput molecular biology, antibody/binder discovery, and protein engineering. We are seeking a skilled Research Associate/Senior Research Associate with experience in utilizing display technologies (yeast/phage) in protein engineering, directed evolution, or binder discovery.
Scientist/Senior Scientist, Protein Engineering Systimmune IncScientist/Senior Scientist, Protein EngineeringRedmond, WA$90,000–$130,000 / yearIt specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). Design novel platforms for faster evaluation and screening of immune-based repertoires from immunized animal sources or display methods for use in both discovery and protein engineering campaigns.
Scientist/Senior Scientist, Protein Engineering SystimmuneScientist/Senior Scientist, Protein EngineeringRedmond, WAFull timeIt specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). Design novel platforms for faster evaluation and screening of immune-based repertoires from immunized animal sources or display methods for use in both discovery and protein engineering campaigns.
Research Associate/Senior Research Associate, Protein Engineering SystimmuneResearch Associate/Senior Research Associate, Protein EngineeringRedmond, WAFull timeThe ideal candidate will be a quick learner with a broad experience set with direct expertise in a display technology and/or an adjacent field including but not limited to high throughput molecular biology, antibody/binder discovery, and protein engineering. We are seeking a skilled Research Associate/Senior Research Associate with experience in utilizing display technologies (yeast/phage) in protein engineering, directed evolution, or binder discovery.
Director, Protein Engineering SystimmuneDirector, Protein EngineeringRedmond, WAFull timeThe Director will own and continue evolving the next-generation yeast display platform built to integrate directly with the FUSE automation wet lab, lead a team of scientists and research associates executing display-based discovery and engineering campaigns, and partner closely with discovery biology, antibody discovery, CMC, and computational teams to deliver optimized lead molecules into the pipeline. Strong working knowledge of antibody and binder formats (IgG, Fab, scFv, VHH) and engineering strategies including affinity maturation, stability and developability optimization, and conditional activation.
Principal Scientist, AI Protein Sciences (Discovery Platforms & Automation) Systimmune IncPrincipal Scientist, AI Protein Sciences (Discovery Platforms & Automation)Redmond, WA$150,000–$200,000 / yearThis position is ideal for a scientist who has experience building or significantly expanding experimental platforms and wants to take technical ownership of automation strategy, technology selection, workflow architecture, and scientific execution. This role will focus on building scalable capabilities in cell-free protein expression, purification, high-throughput binding characterization, sample handling and data analysis through the integration of AI, laboratory automation and robotics.
Associate Consultant, Toxicology WSP Global IncAssociate Consultant, ToxicologyRedmond, WAWith minimal supervision, assist with collecting, extracting, identifying, and compiling chemical and environmental data from organisms and samples of air, soil, water, sludge, and other matrices for research, projects, investigations, and surveys pertaining to toxicology, industrial hygiene, human health risk assessment, and/or emergency response. Assist technical staff and project managers with toxicological and environmental risk identification and assessment, offering input and analysis with low-level threat mitigation activities and remediation projects involving the adverse effects of chemical substances on living organisms and exposure to toxins and toxicants.
Research Scientist/Engineer Assistant - Department of Global Health (Temporary) University of WashingtonResearch Scientist/Engineer Assistant - Department of Global Health (Temporary)Seattle, WAThe individual will also contribute to ongoing research aimed at enhancing diagnostics for sexually transmitted infections, investigating commensal bacteria as potential reservoirs of antimicrobial resistance transferable to _Neisseria gonorrhoeae,_ and investigating the host-pathogen interactions underlying gonococcal infections **.** The successful candidate will be highly responsible, meticulous, and very organized. Candidates should have acquired basic microbiology skills and should be interested in spending much of their time preparing antimicrobial-containing culture media for susceptibility testing, and be willing to learn and demonstrate competency in performing bacterial antimicrobial susceptibility testing.
Senior Associate, Quality Assurance Lyell Immunopharma IncSenior Associate, Quality AssuranceBothell, WA$75,000–$95,000 / yearIn our quest to advance next-generation CAR T-cell therapies, we have built a fully integrated company capable of discovering new technologies, translating science into therapies, manufacturing cell therapy products, and clinically evaluating them in patients. Lyell's product candidates are enhanced with novel technology designed to generate T cells that resist exhaustion and have qualities of durable stemness in order to drive durable tumor cytotoxicity and achieve consistent and long-lasting clinical response.