Vice President, Biochemistry and Head of Early Discovery Projects Parabilis MedicinesVice President, Biochemistry and Head of Early Discovery ProjectsCambridge, MA$310,000–$340,000 / yearGuide projects from target evaluation and hit discovery through hit-to-lead and successful transition into late discovery, partnering with project teams to establish scientific strategy and execution plans, evaluate key scientific inflection points, recommend strategic pivots when needed, and drive critical go/no-go decisions. Mentor and develop early discovery project leaders, fostering scientific growth, strategic thinking, and strong program leadership capabilities across the organization while helping build the next generation of discovery leadership within Parabilis.
Scientist I, Biochemistry and Biotherapeutics PharmaEssentia U.S.A.Scientist I, Biochemistry and BiotherapeuticsBEDFORD, MAExperience with antibody, multi-specific, or other protein-based therapeutics, including formatting, production and high-throughput characterization via affinity (SPR, BLI, Carterra), epitope, developability and cellular functional assays (cytotoxicity, antibody internalization, MSD assay). Demonstrated ability to independently advance scientific projects, collaborate cross-functionally, and communicate scientific findings clearly through written reports, presentations, publications, patents, or related scientific outputs.
Assistant Professor of Biochemistry Brandeis UniversityAssistant Professor of BiochemistryWaltham, Massachusetts$67,000–$85,000 / yearTeaching responsibilities will span the Biochemistry and Biology/HSSP programs and include an introductory and advanced introductory biochemistry class (BCHM 88 and BCHM 100), a project lab in protein biochemistry (BIOL 251), an elective course targeting Biochemistry majors (e.g., BIBC 126 Molecular Mechanisms of Disease), and an elective course appropriate for non-majors (e.g., CDSC 7Culinary Chemistry), totaling five courses per year. The pay offered to a selected candidate during hiring will be based on factors such as (but not limited to) the scope and responsibilities of the position, the candidate's work experience and education/training, internal peer equity, and applicable legal requirements.
Senior / Principal Scientist, Biochemistry Treeline Biosciences, Inc.Senior / Principal Scientist, BiochemistryWatertown, MA$158,000–$184,000 / yearThe successful candidate for the Senior / Principal Scientist, Biochemistry position will have a critical role in supporting Treeline's drug discovery programs by collaborating closely with a multi-disciplinary team of biology, biophysics, structural biology, computational, and medicinal chemistry scientists to deliver high-quality results and drive small molecule drug discovery. Treeline Biosciences is an innovative biotechnology company, founded by an experienced team of biopharmaceutical scientists and executives, committed to developing new medicines against difficult to drug targets in cancer and other life-threatening diseases.
NewCo-op, Protein Sciences (Spring 2027, open to Northeastern students only) Ampersand BiomedicinesCo-op, Protein Sciences (Spring 2027, open to Northeastern students only)Boston, MassachusettsThe submission of unsolicited resumes by recruitment or staffing agencies to Ampersand and/or Flagship Pioneering or its employees is strictly prohibited unless contacted directly by Ampersand or Flagship Pioneering’s internal Talent Acquisition team. Execute assays such as BLI (quantitation, binding kinetic, epitope binning), SPR and other characterization methods like SDS-PAGE and analytical HPLC (SEC, HIC).
Mrna Analytical Development Scientist - Analytical Sciences SanofiMrna Analytical Development Scientist - Analytical SciencesWaltham, MA$85.50–$123.50 / hourIn order to strengthen the Biochemical and Biophysical group in R&D Analytical Sciences Department, Sanofi Pasteur is looking for a skilled and highly motivated individual to develop novel methods and improve characterization of mRNA vaccines in development by working closely with the bioprocess development group. Analytical Sciences Department has the overall responsibility to develop, qualify and validate robust analytical methods to support release and characterization testing of mRNA Drug Substances and Drug Products candidates in development.
NewDirector or Senior Director, Regulatory CMC Kymera TherapeuticsDirector or Senior Director, Regulatory CMCWatertown, MA$195,000–$330,000 / yearHaving advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Lead the development and execution of global regulatory CMC strategies for degrader programs across all stages of development, from early-stage activities through late-stage development and approval with specific emphasis on late-stage activities.
Associate Scientist, Protein Science Alloy TherapeuticsAssociate Scientist, Protein ScienceWaltham, MA$93,000–$110,000 / yearAbout the Role In this role, you will support Alloy Discovery Services programs by executing protein science workflows central to antibody discovery, including transient transfection, recombinant DNA cloning, and immunogen design. Deliver : Apply rigorous scientific thinking to experimental design and execution while maintaining thorough documentation; communicate results clearly to stakeholders to enable informed decision-making and project advancement.
Scientist/Sr. Scientist, Protein Purification Zealand PharmaScientist/Sr. Scientist, Protein PurificationCambridge, MassachusettsWorking knowledge of analytical characterization techniques, including mass spectrometry, biophysical methods (e.g., DLS, MALS, SPR, BLI, DSF), and flow cytometry, sufficient to collaborate effectively with analytical specialists. As a Scientist or Senior Scientist in Protein Purification and Analysis, you will play an important scientific role supporting discovery programs, with a primary emphasis on high-quality purification of protein-based therapeutics and their bioconjugates.
Associate Scientist, Protein Engineering Zealand PharmaAssociate Scientist, Protein EngineeringCambridge, MassachusettsCombining more than 25 years of peptide R&D expertise with a proprietary data platform that leverages advanced data-driven and AI/ML approaches, Zealand Pharma aims to lead a new era in obesity and metabolic health. The site is a highly collaborative, multidisciplinary discovery hub integrating computational research, chemistry, and biology, and is deeply connected to the Greater Boston life sciences ecosystem.
Scientist/Sr. Scientist, Protein Purification Zealand Pharma A/SScientist/Sr. Scientist, Protein PurificationCambridge, MA$125,000–$170,000 / yearWorking knowledge of analytical characterization techniques, including mass spectrometry, biophysical methods (e.g., DLS, MALS, SPR, BLI, DSF), and flow cytometry, sufficient to collaborate effectively with analytical specialists. As a Scientist or Senior Scientist in Protein Purification and Analysis, you will play an important scientific role supporting discovery programs, with a primary emphasis on high-quality purification of protein-based therapeutics and their bioconjugates.
Associate Scientist, Protein Engineering Zealand Pharma A/SAssociate Scientist, Protein EngineeringCambridge, MA$85,000–$125,000 / yearCombining more than 25 years of peptide R&D expertise with a proprietary data platform that leverages advanced data-driven and AI/ML approaches, Zealand Pharma aims to lead a new era in obesity and metabolic health. The site is a highly collaborative, multidisciplinary discovery hub integrating computational research, chemistry, and biology, and is deeply connected to the Greater Boston life sciences ecosystem.
Principal Scientist, Protein Design ModernaTXPrincipal Scientist, Protein DesignCambridge, MassachusettsThis role will lead the design, execution, and continuous advancement of high-throughput mammalian cell–based screening platforms that interrogate broadly applicable design principles for glycoprotein antigens, enabling antigen optimization, improved expression and durability across multiple programs, and rapid maturation of computationally designed candidates. The candidate in this position will work closely with and report to the Senior Director, Computational Design and In Vitro Selection, and will also work closely with the VP, Protein Design, as well as other members of Research, to advance novel candidates to the clinic, drive exploratory trials to inform the generation of improved vaccine antigens and explore new concepts for mRNA medicines.
Scientist-Principal Scientist, Protein Design & Structure Superluminal MedicinesScientist-Principal Scientist, Protein Design & StructureBoston, MassachusettsThe successful candidate will be a subject matter expert (SME) in membrane protein biochemistry, responsible for developing and implementing strategies to express, purify, and characterize challenging G-protein coupled receptors (GPCRs) to support structural biology, biophysics, and drug discovery programs. D. in Biochemistry, Molecular Biology, Biophysics, or a related field with 2+ years (Scientist), 5+ years (Senior Scientist), or 8+ years (Principal Scientist) of relevant experience; or a master’s or bachelor’s degree in a related field with commensurate industry experience.
Principal Scientist - Protein Formulation & Biophysical Characterization (High-Concentration Biologics) PfizerPrincipal Scientist - Protein Formulation & Biophysical Characterization (High-Concentration Biologics)Andover, MA$106,000–$176,600 / yearDirect hands-on experience with biophysical/analytical characterization techniques and data interpretation including proficiency with a broad suite of techniques (DLS, DSC, DSF, SEC-MALS, NTA, CD, FTIR, fluorescence spectroscopy, rheology); ability to design and interpret multi-technique characterization studies. PhD in Pharmaceutics, Pharmaceutical Sciences, Biophysical Sciences, Biochemistry, Chemistry, Biomedical or Chemical Engineering, or related disciplines with 3-5 years relevant experience in biologics formulation, biophysics, or drug product development (industry experience preferred).
Postdoctoral Scientist - Lysosomal Biology & Neuroprotective Mechanisms Eli Lilly and CompanyPostdoctoral Scientist - Lysosomal Biology & Neuroprotective MechanismsBoston, MA$58,000–$123,200 / yearOur current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women's Initiative for Leading at Lilly (WILL). The successful candidate will bring deep expertise in LC-MS-based lipidomics, metabolomics, and proteomics profiling, and in combination with transcriptomic and immunoproteomic/ligand-binding platforms will bring deeper understanding on the interactions between metabolic state and lysosomal health.
Scientist Ii/Senior Scientist, Protein Sciences - Cell Binding Assays Manifold BioScientist Ii/Senior Scientist, Protein Sciences - Cell Binding AssaysBoston, MA$125,000–$175,000 / yearManifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively multiplexed in vivo screening to unlock tissue-targeted medicines and organism-scale models of living systems. Develop, optimize, and qualify cell-based binding assays (flow cytometry / FACS, cell ELISA, and equilibrium binding formats) to characterize antibody-type molecules across a range of formats.
Protein Purification Scientist Pioneer DataProtein Purification ScientistCambridge, MAYou may participate in the company group medical insurance plan Job Description: We are seeking a highly motivated scientist to join the Molecular Profiling & Bioconjugation group in BioMedicine Design at Client. Fast learner, detail oriented and highly organized; ability to effectively plan and complete experiments with limited supervision after fully trained.
Senior Field Application Scientist, Protein XI Meso Scale DiscoverySenior Field Application Scientist, Protein XIBoston, MAThis salary range represents a general guideline as MSD considers other factors when presenting an offer of employment, such as scope and responsibilities of the position, external market factors, and the candidate's knowledge, skills, abilities, education and experience. The Senior FAS, Protein XI will provide advanced technical support, engage in hands-on method development during an initial rotation at MSD headquarters, and mentor junior members of the Field Applications team.
Senior Director, Protein Analytics & Biophysics Generate BiomedicinesSenior Director, Protein Analytics & BiophysicsSomerville, MassachusettsSuccess in this role will require enterprise leadership: developing leaders and senior scientists, building an inclusive and high-accountability culture, partnering deeply across Protein Sciences, Prototyping, Technology, Data Sciences, Machine Learning, Biology, and CMC/Tech Ops, and translating an ambitious scientific vision into robust capabilities that improve decision quality, speed, and scale. The ideal candidate brings deep technical breadth, a quantitative mindset, and a clear point of view on how pooled assays, DNA/barcode-enabled readouts, synthetic biology, automation, microfluidics, advanced detection, and computational modeling can transform how protein therapeutics are evaluated.