38 Results for

Biochemistry Jobs in Littleton, MA

Jobs

New!

Cambridge, MA2 days ago

$126,400–$189,600 Per Year

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careersAboutAlnylamWe are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).Alnylam's robust Total Rewards package is designed to support your overall health and well-being.

Lexington, MA30+ days ago

$28–$32 Per Hour

With a focus on developing differentiated product candidates that are designed to alter TGF- signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. Support protein production efforts, including expression in mammalian systems, purification to achieve high quality reagents using FPLC, affinity, ion-exchange, and SEC chromatography, and continuous optimization of production methods for novel biomolecules.

Lexington, MA30+ days ago

$28–$32 Per Hour

Protein expression: assist with routine mammalian expression of our therapeutic molecules to support ongoing studies, assess novel drug candidates through transient expression with CHO and HEK cells, establish stable cell-lines of new drug candidates when necessary. With a focus on developing differentiated product candidates that are designed to alter TGF- signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue.

Boston, MA30+ days ago

$41,643–$42,000

The candidate will work on NIH grant support investigations into how transposons mobilize and become expressed in model organism cells, like Drosophila, mouse and mosquito cells. Our group studies basic gene regulation mechanisms by small RNAs and the RNA interference pathway in model organisms.

Natick, Massachusetts30+ days ago

$125,000–$155,000 Per Year

You will be responsible for: Analyzing scientific information to address microbiological, biological, and material science matters related to microbiological contamination root cause analysis, forensics, and product development, but also including a wide range of topics from medical devices and pharmaceuticals to consumer products and electronics. A strong theoretical and practical knowledge of various microbiological and biological assays (such as nucleic acid amplification tests, immunoassays, bacterial culture, protein quantification, and enzyme assays) and how material interactions can impact those techniques.

BEDFORD, MA30+ days ago

Full-time

Required QualificationsPhD in Immunology, Protein Engineering, Biochemistry, Molecular Biology, or a related field, with 7+ years of relevant industry experience in biologics or protein therapeutics discovery (4+ years for Senior Scientist level). The successful candidate will combine deep expertise in protein engineering, antibody and multispecific formats, and immuno-oncology biology with strong scientific leadership and hands-on execution.

Waltham, MA22 days ago

$40–$49 Per Hour
Contractor

Key Requirements and Technology Experience: Skills-MASS SPECTROMETR, automation liquid handler, Method development and troubleshooting Master’s degree in Analytical Chemistry, Biochemistry, or a related discipline with 2-4 years of relevant biotechnology or pharmaceutical industry experience, preferably performing impurity monitoring using LC-MS or proteome/HCP profiling or Doctorate degree with 1-3 years of relevant experience in proteomics. Key Responsibilities: Perform characterization testing of gene therapy samples to determine and quantify host cell proteins using solid-phase enhanced sample preparation and LC-MS analytical techniques commonly used in proteomics (i.e. proteomic profiling using DDA or DIA, targeted quantitation using MRM or PRM).

Boston, MA14 days ago

$170,000–$190,000 Per Year

Every team member plays a crucial role in driving the future of biotech research, building the world's most efficient sequencing engine that operates overnight and scales globally. This role is heavily bioinformatics-focused, emphasizing deep domain expertise and the building of scalable products over general software platform skills.

Cambridge, MA30+ days ago

Develop and oversee ligand-binding immunoassays (ELISA, MSD, Luminex or similar platforms) for the detection of translated proteins and anti-drug or anti-protein antibodies, including screening, confirmatory, and neutralizing antibody assays in accordance with regulatory guidance. You will be a subject matter expert in nucleic acid and protein bioanalysis, working to generate critical data that informs decision-making across preclinical and clinical development.

Waltham, MA22 days ago

$50–$53 Per Hour
Contractor

Key Responsibilities Perform characterization testing of gene therapy samples to determine and quantify host cell proteins using solid-phase enhanced sample preparation and LC-MS analytical techniques commonly used in proteomics (i.e. proteomic profiling using DDA or DIA, targeted quantitation using MRM or PRM). Basic Qualifications Masters degree in Analytical Chemistry, Biochemistry, or a related discipline with 2-4 years of relevant biotechnology or pharmaceutical industry experience, preferably performing impurity monitoring using LC-MS or proteome/HCP profiling or Doctorate degree with 1-3 years of relevant experience in proteomics.

Newton, Massachusetts30+ days ago

$99,450–$177,000 Per Year
Full-time

The ideal candidate should have demonstrated wet lab experience working independently in a biophysics, chemistry, biochemistry, or molecular biology laboratory, have exceptional attention to detail, be creative, and be able to critically analyze data and communicate results to the team. Responsibilities: • Support and spearhead the method development and optimization of novel molecular biology assay schemes for spatial omic applications including molecular barcoding, fluorophore marking, nucleic acid hybridization, amplification and sequencing techniques, and probe library preparation.

Worcester, Massachusetts8 days ago

The Aroian Group at UMass Chan Medical School in Worcester, Massachusetts seeks an enthusiastic and motivated Research Associate to join us in developing new cures for intestinal nematode parasites to advance global and animal health. Requirements noted for RA I plus: 5+ years of relevant research experience with a Bachelor’s Degree in Biological or Natural Science or 3+ years relevant research experience with a related Master’s degree.

Lexington, MA30+ days ago

$65–$74 Per Hour

With a focus on developing differentiated product candidates that are designed to alter TGF- signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. Our group exploits multidisciplinary approaches in protein sciences and protein engineering, to better the understanding of the biochemical, biophysical, and structural functional properties of the biomolecules within the TGF- superfamily that drive the signaling pathway.

Lexington, MA30+ days ago

$28–$32 Per Hour

With a focus on developing differentiated product candidates that are designed to alter TGF- signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. Any resume submitted by an agency without a signed contract or expressed consent by a member of the Keros Therapeutics Human Resources Department, will be considered property of Keros Therapeutics, and no fee shall be owed with respect thereto.

Waltham, MA30+ days ago

Full-time

This LC–MS-focused role involves generating and interpreting data on oligonucleotide exposure, stability, metabolism, protein binding, and structural integrity to answer DMPK-relevant questions and link analytical findings with PK/PD and biological activity. Exposure & Disposition: Apply LC–MS and other methods to assess oligonucleotide–protein interactions, binding, and disposition, interpreting how stability, metabolism, and chemical modifications influence systemic and tissue exposure.

Boston, MA30+ days ago

$140,000–$188,000 Per Year

Demonstrated expertise applying analytical techniques for protein analysis, including binding ELISAs, chromatographic purity assays, cell-based potency assays, extended characterization, routine compendial assays, and analytical comparability in support of commercialization. We have a robust pipeline of novel product candidates designed to target multiple key biological pathways to drive an effective anti-tumor response, including angiogenesis modulation, immune activation within the tumor microenvironment, and reduction of tumor-driven immunosuppression.

Boston, Massachusetts30+ days ago

$60–$65 Per Hour

Agreeing to the Atrium Terms and Conditions, includes permission to use the email address and mobile phone number you provide during the application process or throughout the duration of your prospective or actual employment to notify you of job openings, profiles, articles, news, and other employment-related information, as well as to notify you of special promotions or additional products and services offered by us or our affiliates and partners. The Cell Hub is dedicated to the maintenance, tracking, quality control (QC), and production of cell biomass for critical assays and high throughput screenings, as well as the development of innovative techniques for large-scale production of complex cell models.

Boston, MA30+ days ago

$67,500–$70,000

Demonstrated experience (ideally publications or preprints) in one or more of the following areas is highly desirable: Tissue culture, including flow cytometry, toxicity assays and generation of stable cell lines. Working with our unique archive of clinical data and samples, the successful candidate will apply a range of approaches including protein biochemistry and cell biology to model systems and patient samples.

Waltham, MA30+ days ago

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. In this role, you’ll play a key part in analyzing a diverse range of molecules generated through fermentation and enzyme catalysis, while working closely with a collaborative team of scientists across disciplines.

Cambridge, MA24 days ago

Temporary

You will work on organizing categorizing and streamlining biological materials such as cells plasmids and development samples while partnering with Technical Operations Development and Quality teams to ensure materials are properly labeled and maintained. As a Technical Operations and Development Intern at Beacon Therapeutics USA Inc you will support a key inventory management initiative focused on gene therapy R and D and CMC development materials at an external storage vendor.

Boston, Massachusetts30+ days ago

There are two primary functions of this position: 1) Culturing human iPSCs and differentiating them in neurons and glia cells, 2) Characterization of cultures with biochemistry, microscopy and molecular biology (Protein extraction Western blotting, ELISA, immunostaining and microscopy, RNA and DNA extraction, PCR and qPCR, genome editing). Overview: The Department of Neuroscience is a basic science department that focuses on cutting-edge research in the areas of neurological disease.

Boston, Massachusetts30+ days ago

The ideal candidate will be able to help evolve Monte Rosa’s hit identification and hits-to-leads endeavors through embracing novel assay technologies, enhancing overall process and actively drive internal and external partnerships. Overview: Monte Rosa Therapeutics is seeking a passionate Contractor High Throughput Cellular Assays with the experience to implement and run complex cellular assays for a 6-month contract.

Boston, MA30+ days ago

As a Senior Scientist Immunology overseeing the design and execution of in vitro and in vivo mechanistic, proof-of-concept and safety studies, provide scientific and technical expertise in immune cell biology, and support regulatory filing with authoring of technical reports. · Establish and validate in vitro models of autoimmune diseases; support the design and execution of in vivo experiments such as PK, tox, dosing.

Cambridge, MA30+ days ago

$72,000–$102,000 Per Year

Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. You will interact and collaborate cross-functionally with scientists in other departments, including biochemists, chemists, and computational and structural biologists while growing your understanding of drug discovery and helping bring medicines to patients.  .

Boston, MA30+ days ago

Takes full fiscal responsibility for section oversights, including but not limited to: preparing and managing an operating budget, managing staffing expenses and overtime (OT), capital budget, analyzing billing codes, preparing return on investment business analysis, fully supporting the revenue integrity of the Laboratory including accurate charges, billing and collections. Requires a Bachelor's degree from an accredited university or college in Medial Technology or Clinical Laboratory Science which includes successful completion of a supervised course of clinical internship in an approved hospital laboratory, or a Bachelor's degree in an applied science (for example Chemistry, Biology or Biochemistry).

Boston, MA30+ days ago

Requires a Bachelor's degree from an accredited university or college in Medial Technology or Clinical Laboratory Science which includes successful completion of a supervised course of clinical internship in an approved hospital laboratory, or a Bachelor's degree in an applied science (Chemistry, Biology, Biochemistry). Work requires the analytic abilities to perform and review highly complex testing as defined under CLIA '88, to interpret findings, perform calculations, calibrate instruments and so forth; and to assist in developing sound policies and procedures.

Cambridge, MA30+ days ago

Full-time

The DECODE platform has been validated through four strategic partnerships with leading pharmaceutical companies—Bristol Myers Squibb, Genentech, Eli Lilly, and Pfizer—representing over $4.5 billion in disclosed total deal value and $185 million in upfront payments received to date. The successful candidate will bring deep expertise in biologics CMC development, demonstrated success building teams and processes in both early‑stage and mature organizations, and a strong track record of technology transfer and management of external manufacturing organizations.

Worcester, Massachusetts8 days ago

Experimental responsibilities could include the following techniques: molecular biology (PCR, cloning), biochemistry (protein purification), bacterial directed evolution, zebrafish genome-editing, zebrafish line maintenance, antibody staining, RNA in situ analysis, high-resolution imaging, high-throughput larval behavior, adult behavior, cell culture maintenance, drug screens, transcriptomics (bulk and single-cell RNA-seq), mouse perfusion, mouse brain dissection, and mouse husbandry. Responsibilities will include collecting, organizing, and reporting research data under minimal supervision; assisting in the design of experiments; maintaining laboratory supplies and equipment; instructing others in basic laboratory techniques; collecting and summarizing data; monitoring results; reporting unusual outcomes.

Cambridge, MA30+ days ago

$270,000–$300,000

This highly visible role will be accountable for the preclinical bioanalytical strategy, biomarker strategy, data quality, and regulatory readiness, ensuring successful EDIT-401 IND submission and Clinical Trial execution. As the Senior Director, Bioanalytical and Biomarker Development, you will: Lead assay development, qualification, validation, and execution for measuring drug product components, immunogenicity, biomarkers, and other analytes in biological matrices.

Natick, Massachusetts30+ days ago

The successful candidate will work closely with senior scientists and cross‑functional teams to execute high‑quality DEL and SELEX screening projects, analyze data, and support timely delivery of results to internal teams and external clients. Overview: DNA‑encoded library (DEL) and SELEX (Systematic Evolution of Ligands by EXponential enrichment) technologies are rapidly expanding drug discovery platforms within the IVBU at WuXi AppTec.

Devens, MA19 days ago

$74,672–$87,152

This role will focus on cryogenics, cold-chain transportation, single-use systems, materials-related technical evaluations, and lab-based studies supporting commercial biopharmaceutical manufacturing operations. Minimum Bachelor’s degree with 2+ years of industry experience, or Master’s degree in Chemical Engineering, Biochemical Engineering, Chemistry, Biochemistry, Biology, or a related scientific discipline.

Waltham, MA30+ days ago

$58,000–$65,000

Develop, perform, interpret, and troubleshoot a broad range of in vitro assays including immune cell profiling, cytokine profiling, functional assays using primary cells, as well as cytotoxicity/apoptosis assays using primary and/or cultured cells. Its service platform integrates preclinical studies with innovative animal models, CRISPR-based gene editing, and animal supplies, with the current focus on immuno-oncology and oncology.

Boston, Massachusetts30+ days ago

1. Sales Behaviors: · Respond to customer requests in a timely manner and leverage the appropriate overlays (Tech Serv, North America Marketing (NAM), Cust Serv, Field Support Scientist (FSS), Global Clinical Collaborations Manager (GCCM), Clinical Account Consultant (CAC), Strategic Collaborations Management Team (SCMT), Strategic Product Manager (SPM), Strategic Business Unit (SBU), Elite Access, R&D etc.) as necessary to ensure customer satisfaction. · Works closely with Regional/Associate/sales manager to develop opportunity-based pricing strategies at accounts (quotes, purchasing contracts with discount schedules, freezer programs and stockroom/consignment).

Boston, Massachusetts19 days ago

Incorporate the Core ESI Principles in their position (check in with yourself, listen with empathy, enhance self-esteem, look for the good, with discernment, encourage diverse perspectives and use courage and compassion to say what needs to be said). 2. In collaboration with the senior management team, broadly monitor regional performance, developing clear action plans to optimize team efficiencies.

New!

Milford, Massachusetts3 days ago

We collaborate with customers around the world to advance the release of effective, high-quality medicines, ensure the safety of food and water, and drive better patient outcomes by detecting diseases earlier, managing routine infections, and combating antibiotic resistance. Qualifications: Requirements include a Bachelor’s Degree or equivalent in Chemistry, Biochemistry, Life Sciences or related field with at least five to eight years of experience in job related field of Liquid Chromatography (LC) and Mass Spectrometry (MS) in Biomolecule MS applications.

Cambridge, MA30+ days ago

$110,000–$125,000 Per Year

Its lead asset, zolucatetide (FOG-001), is a first-in-class, clinically validated direct inhibitor of the interaction between -catenin and the T-cell factor (TCF) family of transcription factors, implicated in millions of cancer cases annually, including in colorectal cancer, desmoid tumors, hepatocellular carcinoma and a range of other Wnt/-catenin-driven tumors. We are fiercely independent as a leader in defying the limitations of current therapeutic modalities, and interdependent as a team as we work collaboratively to shift drug discovery paradigms and provide patients with better treatment options.

New!

Boston, Massachusetts3 days ago

The Senior Research Associate II level will have 4-6 years of relevent industrial experience and a Scientist wiill pocess 1-2 years industrial exerience. The ideal candidate will have strong expertise in developing high-throughput cellular assays for screening and compound profiling.

Lexington, MA21 days ago

$116,400–$140,000 Per Year

These capabilities are applied to missions spanning chemical, biological, and explosives (CBE) detection and attribution; medical diagnostics and countermeasures; pathogen identification; point-of-care diagnostics; molecular intelligence; biosecurity; biomanufacturing, DNA forensics, and additive manufacturing. These projects include development of sensing materials for detecting chemicals and proteins, supporting analysis and down-stream processing of bio-manufactured materials, trace detection of threat chemicals, and the synthesis and formulation of small molecules and polymers.

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Biochemistry Jobs in Littleton, MA

Senior Scientist, Cell Biology Alnylam Pharmaceuticals

Research Associate Co-Op, Protein Biochemistry/Engineering Keros Therapeutics

Research Associate Co-Op, Protein Biochemistry Keros Therapeutics

LABORATORY TECHNICIAN, BS-Biochemistry - Lau Lab Boston University

Scientist (Ph. D.) Exponent Inc.

Principal/ Senior Scientist – T Cell Engager & Multispecific Protein Engineering PharmaEssentia U.S.A.

Scientist I Pyramid, Inc

Bioinformatics Scientist Vivo HealthStaff

Senior Scientist, Bioanalytical Sciences CEDENT

Scientist I Integrated Resources, Inc

Senior Scientist Bruker

Research Associate I- NEP University of Massachusetts Medical School

Contract Senior Research Associate, Protein Science Keros Therapeutics

Research Associate Co-Op, Preclinical Research - Muscle, Bone and Stem Cell Biology Keros Therapeutics

Scientist / Senior Scientist, Bioanalytical LC–MS – Oligonucleotide Alloy Therapeutics

Principal Analytical Scientist, CMC Compass Therapeutics

Research Scientist – Cell Biologist, High Throughput Human Biology (Contract) Vertex Pharmaceuticals

Postdoctoral Associate, Amyloidosis Center, Boston University Chobanian Avedisian School of Medicine Boston University

Research Associate, Analytical Chemistry Manus

Technical Operations and Development Intern - Hybrid Beacon Therapeutics (USA) Inc

Research Technician, Neuroscience Tufts University

Contractor High Throughput Cellular Assays (6 Months) Monte Rosa Therapeutics, Inc

Senior Scientist Immunology CEDENT

Senior/Research Associate, Biology Relay Therapeutics

Manager Laboratory Medicine (Hematology) Boston Medical Center

Assistant Supervisor -Phlebotomy Services (40Hrs Evenings)($5 000 Sign-on bonus external candidates Boston Medical Center

Vice President, Head of CMC Repertoire Immune Medicines

Research Associate I - NEP University of Massachusetts Medical School

Senior Director, Bioanalytical and Biomarker Development Editas Medicine

DEL Platform Scientist II WuXi AppTec

Assistant / Associate Scientist - MSAT Materials & Cryogenics SOKOL GxP Services

Pharmacology Research Associate Biocytogen

Client Representative - Boston Promega

Manager, Regional Sales Promega

Senior MS Applications Specialist Waters Corporation

Scientist I, Peptide Drug Discovery Parabilis Medicines

Senior Research Associate = High Throughput Cellular Pharmacology Monte Rosa Therapeutics, Inc

Chemist MIT Lincoln Laboratory

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