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Takeda Research is constructing a Lab of Tomorrow built on AI, automation, new ways of working, and talent with the singular vision of delivering differentiated medicines to the clinic at speed and cost.
Boston, Massachusetts15 days ago
The successful candidate will be a subject matter expert (SME) in membrane protein biochemistry, responsible for developing and implementing strategies to express, purify, and characterize challenging G-protein coupled receptors (GPCRs) to support structural biology, biophysics, and drug discovery programs. D. in Biochemistry, Molecular Biology, Biophysics, or a related field with 2+ years (Scientist), 5+ years (Senior Scientist), or 8+ years (Principal Scientist) of relevant experience; or a master’s or bachelor’s degree in a related field with commensurate industry experience.
Lexington, MA30+ days ago
With a focus on developing differentiated product candidates that are designed to alter TGF- signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. Our group exploits multidisciplinary approaches in protein sciences and protein engineering, to better the understanding of the biochemical, biophysical, and structural functional properties of the biomolecules within the TGF- superfamily that drive the signaling pathway.
Cambridge, Massachusetts4 days ago
This is a highly collaborative, hands-on role requiring scientific independence and a strong focus on delivering well-characterized, high-quality protein and conjugate inputs to enable downstream assay development and candidate selection. Ring Therapeutics was founded in Flagship Pioneering’s venture creation engine, where companies such as Moderna Therapeutics (NASDAQ: MRNA) and Generate Biomedicines (NASDAQ: GENB) were conceived and created.
p>Required Skills: ADME, Assay Development, Bioanalysis, Bioanalytical Assays, Bispecific Antibodies, Communication, Cross-Cultural Awareness, Drug Discovery Development, Drug Metabolism, Fast-Paced Environments, Immunology, Immunotherapy, Innovation, Ligand Binding Assay, Modeling Simulations, Monoclonal Antibodies, Oncology, People Leadership, Pharmacokinetics, PKPD Modeling, Protein Engineering, Results-Oriented, Scientific Leadership, Strategic Thinking, Therapeutic Proteins. D (with 7+ years relevant experience) degree in biochemistry, pharmacology, pharmaceutical sciences, protein engineering, molecular biology, bioengineering, or related STEM field; Relevant experience that includes a record of increasing responsibility and independence in a similar industrial/academic setting.
p>Building on the idea of creating smart therapies based on Boolean logic circuits, Strand was started by biological engineers working together at MIT who were seeking to apply the concept of the emerging field of mRNA therapeutics. Reporting to the Director of Process Development, this individual will serve as the technical lead for Process Sciences & Innovation, partnering closely with Analytical Development and Research, to identify, evaluate, and implement next-generation technologies that enhance process understanding, development efficiency, scalability, and product quality.
li>Direct hands-on experience with biophysical/analytical characterization techniques and data interpretation including proficiency with a broad suite of techniques (DLS, DSC, DSF, SEC-MALS, NTA, CD, FTIR, fluorescence spectroscopy, rheology); ability to design and interpret multi-technique characterization studies.
PhD in Pharmaceutics, Pharmaceutical Sciences, Biophysical Sciences, Biochemistry, Chemistry, Biomedical or Chemical Engineering, or related disciplines with 3-5 years relevant experience in biologics formulation, biophysics, or drug product development (industry experience preferred).
li>Direct hands-on experience with biophysical/analytical characterization techniques and data interpretation including proficiency with a broad suite of techniques (DLS, DSC, DSF, SEC-MALS, NTA, CD, FTIR, fluorescence spectroscopy, rheology); ability to design and interpret multi-technique characterization studies.
PhD in Pharmaceutics, Pharmaceutical Sciences, Biophysical Sciences, Biochemistry, Chemistry, Biomedical or Chemical Engineering, or related disciplines with 3–5 years relevant experience in biologics formulation, biophysics, or drug product development (industry experience preferred).
Norton, Massachusetts30+ days ago
Perform routine/non-routine analytical (HPLC/UPLC) and/or microbiological assays for raw materials, in-process samples, product release, and stability studies following SOPs. R&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering.
Cambridge, Massachusetts15 days ago
p>LILA combines advanced AI models with proprietary AI Science Factory instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team.
This salary range represents a general guideline as MSD considers other factors when presenting an offer of employment, such as scope and responsibilities of the position, external market factors, and the candidate's knowledge, skills, abilities, education and experience. The Senior FAS, Protein XI will provide advanced technical support, engage in hands-on method development during an initial rotation at MSD headquarters, and mentor junior members of the Field Applications team.
Somerville, MA30+ days ago
Responsibilities include delivering high-quality antibodies and protein reagents for multiple simultaneous biologics discovery programs, enabling discovery platform optimization, managing a team of direct and indirect reports, and coordinating both in-house and outsourced protein expression, purification, and characterization activities. As a member of the Biotherapeutics & Enabling Technologies leadership team, this scientific leader will work closely with the head of the unit to establish and maintain a Protein & Cell Sciences function that maximizes the ability the potential for Metaphore's platform to deliver transformative therapeutics to patients.
Perform routine and non-routine microbiological assays (bioburden, TOC, endotoxin, conductivity), with increasing complexity, to support critical utility samples, in-process samples, and product release, following established SOPs Maintain up-to-date training records, adhere to the testing schedule, and ensure the timely completion of all assignments to support the seamless operation of QC activities and uphold the department's commitment to meeting project timelines and quality metrics Assist in the maintenance of laboratory equipment and inventory to ensure smooth laboratory operations Ensure data is submitted timely; may qualify as a data reviewer to ensure timely and efficient data availability. Collaborate with QC and cross-functional teams to ensure seamless quality control operations and to support the collective company goals Participate in inspection readiness activities as well as supporting onsite audits and inspections, as needed.
For this position you'll need the following education, experience and skills: Minimum Qualifications: PhD in related field and/or several years of industrial laboratory-based LC/MS experience (biochemistry, chemistry, molecular & cellular biology, or biophysics) + 6-12 years' experience, BS or MS + 12-18 years' experience. Working in a multidisciplinary team you will apply your expertise to complement the biophysical and biochemical characterizations of recombinant proteins and communicate to stakeholders across the US research organization.
p>LILA combines advanced AI models with proprietary AI Science Factory instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science's internal Talent Acquisition team.
Cambridge, MA30+ days ago
Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program. LILA combines advanced AI models with proprietary AI Science Factory instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy.
Cambridge, MA30+ days ago
This role will lead the design, execution, and continuous advancement of high-throughput mammalian cell-based screening platforms that interrogate broadly applicable design principles for glycoprotein antigens, enabling antigen optimization, improved expression and durability across multiple programs, and rapid maturation of computationally designed candidates. Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team.
Somerville, Massachusetts25 days ago
p>Success in this role will require enterprise leadership: developing leaders and senior scientists, building an inclusive and high-accountability culture, partnering deeply across Protein Sciences, Prototyping, Technology, Data Sciences, Machine Learning, Biology, and CMC/Tech Ops, and translating an ambitious scientific vision into robust capabilities that improve decision quality, speed, and scale. The ideal candidate brings deep technical breadth, a quantitative mindset, and a clear point of view on how pooled assays, DNA/barcode-enabled readouts, synthetic biology, automation, microfluidics, advanced detection, and computational modeling can transform how protein therapeutics are evaluated.
li>Provides nutritional care when consulted for several malnourished and/or critically ill patients; diagnoses malnutrition and documents in EHR using BMC approved malnutrition diagnostic criteria; utilizes the nutrition-focused physical exam to assess nutritional status; evaluates patient's nutritional needs and develops nutritional care plan; determines solutions for total parenteral nutrition and tube feedings when appropriate and submit to MD for approval as well as chart in the medical records.
Additional advanced board certifications preferred for complex patient population:
Certified Nutrition Support Clinician (CNSC), Certified Lactation Counselor (CLC), Pediatric Critical Care Nutrition (CSPCC), Certified Pediatric Nutrition (CSP), Certified Specialist in Obesity and Weight Management (CSOWM), Certified Diabetes Educator (CDE), or other advanced board certification.
p>How you will make an impact: As a key member of Takara Bio USA's Field Applications team, you will play a pivotal role in advancing life science research by supporting the adoption and success of our innovative spatial biology and single-cell NGS technologies.
What will you do:
- Engage with new and existing customers to educate, support and train on Takara Bio Spatial Biology products (Trekker and Seeker) and/or Takara Bio Single Cell NGS instrument platform (Shasta).
You will deliver high-quality antibody and protein reagents across multiple simultaneous biologics discovery programs, enable optimization of our discovery platform, manage a team of direct and indirect reports, and coordinate protein expression, purification, and characterization across both in-house and outsourced operations. Director of Protein & Cell Sciences will lead the team responsible for high-throughput expression, purification, and biophysical characterization of antibodies and related proteins, and for the cell culture, engineering, and scale-up needed to produce material from milligram to multi-gram scale in support of discovery.
Somerville, MA23 days ago
p>Success in this role will require enterprise leadership: developing leaders and senior scientists, building an inclusive and high-accountability culture, partnering deeply across Protein Sciences, Prototyping, Technology, Data Sciences, Machine Learning, Biology, and CMC/Tech Ops, and translating an ambitious scientific vision into robust capabilities that improve decision quality, speed, and scale. The ideal candidate brings deep technical breadth, a quantitative mindset, and a clear point of view on how pooled assays, DNA/barcode-enabled readouts, synthetic biology, automation, microfluidics, advanced detection, and computational modeling can transform how protein therapeutics are evaluated.
p>Job Description: Tracking information for sponsored accounts including updating budgets as needed, projecting personnel and non-personnel expenses, monitoring accounts, reviewing account records for accuracy, reconciling all accounts to Workday and generating reports monthly for the Principal Investigators. Work with personnel in the Division of Science administrative groups as well as Sponsored Programs Accounting, Office of Research Administration, Procurement, Payroll, A&S Dean, and other offices to correct errors or overages.
At Draper Bioengineering, we work at the interface between engineering and biology, and the successful applicant will join teams working on Microphysiological systems (organ-on-chip) and other novel systems that blend complex biology with custom hardware and software. Draper supports many programs to improve work-life balance including workplace flexibility, employee clubs ranging from photography to yoga, health and finance workshops, off site social events and discounts to local museums and cultural activities.
The Analytical Development team is responsible for developing and implementing new analytical methods, as well as optimizing and improving current methods for the characterization of raw materials, RNA drug substances, and LNP products and programs at various development stages. Eurofins is seeking a highly skilled, passionate, and motivated scientist to join our client Analytical Development team to support testing non-GMP samples for development studies such as comparability assessments, process development, stability, product, and process characterization.