FULL_TIME

FEED

YEAR

Frontend / Backend Development – design, implement, and maintain robust data ingestion interfaces leveraging external APIs and clinical ontologies such as SNOMED, MedDRA, and ICD-10, adhering to software engineering best practices including wireframe design, unit testing, version control, code review, and security and compliance. You’ll join near the ground floor of development, getting hands-on experience building the infrastructure, pipelines, and novel analytical workflows to turn raw microbiome data into actionable and high-integrity microbiome intelligence.

Senior Bioinformatics Engineer Compensation: $125K – $200K base +  0.25% - 0.5% equity About BiomeSense BiomeSense is a pioneering life sciences startup focused on harnessing the power of the gut microbiome to revolutionize personalized medicine. With our breakthrough technologies GutLab and MetaBiome, we are setting new standards in microbiome biomarker discovery, data analysis and interpretation, enabling unprecedented insights to understand & leverage the microbiome for human health. We partner with leading institutions and researchers including UCSF, UCSD, NIH, and the University of Chicago, and are backed by investors such as LabCorp Ventures, Bluestein Ventures, Seerave Foundation, and Emil Capital Partners. The Position You’ll help build our MetaBiome platform, a novel software solution for collection, curation and analysis of longitudinal microbiome & health data at scale. This role provides a unique opportunity to be one of the earliest employees at a rapidly growing start-up, contributing across bioinformatics, data engineering, and product development. We’re looking for someone who is excited to build - and someone who has the character and drive to grow into a platform leader over time. You’ll join near the ground floor of development, getting hands-on experience building the infrastructure, pipelines, and novel analytical workflows to turn raw microbiome data into actionable and high-integrity microbiome intelligence.   Key Responsibilities:<ul><li>Bioinformatics Architecture & Infrastructure - help design, implement, and maintain the robust, auditable backend required for the highest-quality extraction of clean microbiome data from raw shotgun metagenomic sequencing data.</li><li>Data Engineering – contribute to the development and maintenance of cloud-based infrastructure, including databases, distributed computing workflows, and REST endpoints, supporting a data platform that organizes microbial sequence data and associated clinical metadata.</li><li>Statistical Analysis – lead the design, execution, and documentation of reproducible computational experiments from concept to conclusion, including experimental design, data preparation, model selection, and evaluation strategies.</li><li>Methods Development – Develop and implement novel analytical methodologies and algorithms informed by experimental findings and validated through rigorous evaluation.</li><li>Frontend / Backend Development – design, implement, and maintain robust data ingestion interfaces leveraging external APIs and clinical ontologies such as SNOMED, MedDRA, and ICD-10, adhering to software engineering best practices including wireframe design, unit testing, version control, code review, and security and compliance. </li></ul> Qualifications Required<ul><li>B.S. /M.S. /PhD in Computational Biology, Bioinformatics, Computer Science or a related field with 3+ yrs industry experience (biotech start-up ideal)</li><li>Strong proficiency in Python and JavaScript, with experience building scalable, reusable, testable, and maintainable software.</li><li>Proficiency with PostgreSQL or other relational SQL database systems.</li><li>Familiarity with clinical ontologies such as SNOMED, ICD-11, ATC, and LOINC.</li><li>Familiarity with Amazon Web Services and best practices in computer security.</li><li>Proficiency with one or more modern frontend web technologies.</li><li>Excellent communication skills for presenting complex scientific concepts to diverse stakeholders.</li><li>Strong ownership mindset and the ability to execute in fast-moving environments.</li><li>Strong fundamentals in bioinformatics pipelines, QC, and reproducibility.</li></ul> Strongly Preferred<ul><li>Bioinformatician with experience working with NGS data and bioinformatics pipeline verification and knowledge of microbiome-specific challenges (compositional data, variability, confounders).</li><li>Familiarity with longitudinal / repeated-measures biological datasets.</li><li>Experience integrating external ontologies or standardized vocabularies.</li><li>Exposure to cloud infrastructure, workflow orchestration, or containerization.</li><li>Interest in AI/ML applications built on large biological datasets.</li></ul>Powered by JazzHR

BiomeSense

Senior Bioinformatics Engineer

Algorithms

Amazon Web Services (AWS)

Analysis Skills

Application Programming Interface (API)

Best Practices

Bioinformatics

Bioinformatics Validation 

Biology

Biomarkers

Biotech and Pharmaceutical

Clinical Data

Cloud Computing

Code Reviews

Communication Skills

Computer Science

Computer Security

Data Analysis

Data Cleaning

Data Management

Data Modeling

Data Sets

Database Technology

Distributed Computing

Documentation

Experiment Design

Human Health

ICD-10

ICD-11

Internet Technology

JavaScript

Medical Dictionary for Regulatory Activities (MedDRA)

Medicine

Metadata

National Institutes of Health (NIH)

Next Generation Sequencing (NGS)

Ontology

PostgreSQL

Product Development

Python Programming/Scripting Language

Quality Control

REST (Representational State Transfer)

Relational Databases (RDBMS)

SQL Databases

Scalable System Development

Software Engineering

Source Code/Configuration Management (SCM)

Startup

Statistics

Test Design

Unit Test

User Interface/Experience (UI/UX)

Wireframes

Workflow Analysis

partner JazzHR

UNKNOWN

ADAPTED_NOW

The position entails leading the departments of Bioengineering, Cell Biology, and Bioinformatics (including 3 Department Leads and a staff of 11) ensuring the discovery team consistently and rapidly produces innovative, market-ready traits for their global plant breeders. D. in Molecular Biology, Plant Biotechnology, Bioengineering, or a related field preferred with 10+ years of experience in biotech or agricultural R&D, with at least 5 years in a senior leadership role managing technical teams.

<ul><li>Our client is a Chicago area based, global horticulture and agriculture product producer and distributor. Due to growth and expansion, the company is seeking to hire an innovation type to lead their discovery team.</li></ul><div></div><ul><li>The position entails leading the departments of Bioengineering, Cell Biology, and Bioinformatics (including 3 Department Leads and a staff of 11) ensuring the discovery team consistently and rapidly produces innovative, market-ready traits for their global plant breeders.</li></ul><ul><li>We want a "creative pragmatist"— a visionary who can create products that don’t yet exist and build the roadmap to create them. We seek the "creative vision" to inspire scientists to redefine biological possibilities, transforming "what if" into "we can." This person will balance their imagination with a laser focus on speed to market, commercial goals, and budgetary discipline. More than a scientist, this role will be an architect of innovation, translating complex synthetic biology into exciting consumer experiences!</li></ul><ul><li>The ideal candidate will have a Ph.D. in Molecular Biology, Plant Biotechnology, Bioengineering, or a related field preferred with 10+ years of experience in biotech or agricultural R&D, with at least 5 years in a senior leadership role managing technical teams. A deep understanding of transformation and regeneration techniques, application of bioinformatic tools and bioengineering is a must.</li></ul><div></div><ul><li>Compensation for this postion is between $150K to $225K per year + Bonus + Relocation to the Chicago area.</li></ul><div></div>

Executive Directions & Pinnacle Int'l

Director of Bio-Innovation

Agriculture

Bioengineering

Botany

Budgeting

Cell Biology

Customer Experience

Horticulture

Leadership

Molecular Biology

Research & Development (R&D)

Team Lead/Manager

Technical Leadership

Top Echelon

OTHER

The Senior BSA plays a critical role in driving project success by translating scientific and business needs into actionable requirements, guiding informatics and data-driven solutions, and ensuring high-quality delivery across complex R&D environments. Familiarity with scientific workflows (e.g., bioanalysis, compound management, medicinal chemistry)and key data concepts within the life sciences industry and relevance to operational activities and enabling decision-making.

Locations:  Boston, MA North Chicago, IL San Diego, CA**This role will require regular on-site presence (3 - 4 days / week) at client site(s)**About Zifo: Zifo is a leading global scientific informatics and digital solutions provider focused on transforming research and development for life sciences organizations. We partner with pharmaceutical, biotech, and agritech companies to drive R&D efficiency, ensure data integrity, and enable scientific innovation through process excellence and technology enablement. Position Overview: Zifo North America is seeking a Senior Scientific Business Systems Analyst (Senior BSA) to support strategic R&D initiatives for pharmaceutical, biotech, and related life sciences customers. This role is responsible for independently leading low-to-medium-complexity business analysis engagements while collaborating closely with customer stakeholders and Zifo’s global delivery teams. The Senior BSA plays a critical role in driving project success by translating scientific and business needs into actionable requirements, guiding informatics and data-driven solutions, and ensuring high-quality delivery across complex R&D environments. This position requires strong scientific domain expertise, consulting acumen, and hands-on experience delivering informatics and data projects in regulated and non-regulated research settings. Key Responsibilities Consulting & Business Analysis <ul><li>Lead and execute business analysis activities across R&D-focused projects with minimal supervision. </li></ul><ul><li>Review and analyze existing business processes, systems, and data flows to identify gaps, risks, and improvement opportunities. </li></ul><ul><li>Conduct voice-of-the-customer sessions, stakeholder interviews, and workshops to elicit and prioritize requirements. </li></ul><ul><li>Perform gap analysis and define future-state process workflows, data models, and system interactions. </li></ul><ul><li>Develop and review core deliverables including User Requirements Specifications (URS), Functional Requirements Specifications (FRS), workflows, implementation roadmaps, gap analysis reports, and training materials. </li></ul><ul><li>Evaluate industry trends and leading practices in scientific informatics to recommend optimized future-state solutions. </li></ul><ul><li>Support vendor evaluations and contribute to implementation strategies for small to mid-size life sciences organizations. </li></ul><ul><li>Contribute to regulatory and data integrity assessments (including GxP where applicable) and support remediation of compliance gaps. </li></ul>Project Execution & Delivery <ul><li>Manage one or more small projects or modules within larger programs, ensuring delivery on scope, schedule, and quality. </li></ul><ul><li>Perform project management activities including effort estimation, task planning, scheduling, and risk assessment. </li></ul><ul><li>Identify, track, and mitigate project risks; proactively address issues and escalate concerns when appropriate. </li></ul><ul><li>Monitor project progress and communicate clear, timely status updates to internal teams and customers. </li></ul><ul><li>Support and mentor junior Business Analysts by guiding deliverable development, planning, and execution. </li></ul><ul><li>Collaborate effectively with global team members (India, EU and LatAm) to deliver on project goals. </li></ul>Customer Engagement & Collaboration <ul><li>Serve as a key point of contact with customers for delivery on assigned engagements, managing expectations related to process, quality, timelines, and outcomes. </li></ul><ul><li>Build strong working relationships with customer stakeholders, including manager-level contacts. </li></ul><ul><li>Proactively sense and address customer concerns before they escalate; collaborate with Solution and Delivery Managers on corrective actions. </li></ul><ul><li>Participate in and support project and client meetings as appropriate </li></ul>Operational Excellence & Business Support <ul><li>Plan, track, and report billable effort accurately and on time. </li></ul><ul><li>Identify opportunities for Zifo to add value within customer organizations and surface potential follow-on engagements. </li></ul><ul><li>Support proposal development and contribute content for presentations, white papers, and thought leadership initiatives. </li></ul>Learning, Mentorship & Continuous Improvement <ul><li>Demonstrate continuous learning in scientific domains, informatics platforms, and consulting methodologies. </li></ul><ul><li>Assist with internal training development and knowledge-sharing initiatives. </li></ul><ul><li>Mentor other analysts within global team, fostering collaboration and high performance. </li></ul><ul><li>Contribute to continuous improvement initiatives, including CAPA activities, defect analysis, and delivery process enhancements. </li></ul>RequirementsQualifications: <ul><li>Bachelor’s or Master’s degree in a relevant scientific discipline such as biology, chemistry, chem/bioinformatics among others </li></ul><ul><li>3-5 years of experience as a Business Analyst or similar role within an R&D organization. </li></ul><ul><li>Experience with informatics solution projects (e.g., ELN, LIMS implementations) </li></ul><ul><li>Familiarity with scientific workflows (e.g., bioanalysis, compound management, medicinal chemistry)and key data concepts within the life sciences industry and relevance to operational activities and enabling decision-making. </li></ul><ul><li>Experience with key data concepts within the life sciences industry and relevance to operational activities and enabling decision-making. </li></ul>Travel Requirements:<ul><li>Some travel (up to 25%) will be required for this role</li></ul>BenefitsCURIOSITY DRIVEN, SCIENCE FOCUSED, EMPLOYEE BUILT. Our culture is unlike any other, one where we debate, challenge ourselves, and interact with all alike. We are a curious bunch, characterized by our passion to learn and spirit of teamwork. Zifo is a global R&D solutions provider focused on the industries of Pharma, Biotech, Manufacturing QC, Medical Devices, specialty chemicals and other research-based organizations. Our team’s knowledge of science and expertise in technology help Zifo better serve our customers around the globe, including 18 of the Top 20 Biopharma companies. We look for Science – Biotechnology, Pharmaceutical Technology, Biomedical Engineering, Microbiology etc. We possess scientific and technical knowledge and bear professional and personal goals.  While we have a “no doors” policy to promote free access within, we do have a tough door to walk in. We search with a two-point agenda – technical competency and cultural adaptability. We offer a competitive compensation package including accrued vacation, medical, dental, vision, 401k with company matching, life insurance, and flexible spending accounts.  If you share these sentiments and are prepared for the atypical, then Zifo is your calling! Zifo is an equal opportunity employer, and we value diversity at our company.  We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Bioinformatics Jobs in Chicago, IL

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Bioinformatics Jobs in Chicago, IL

Senior Bioinformatics Engineer BiomeSense

Director of Bio-Innovation Executive Directions & Pinnacle Int'l

Senior Scientific Business Systems Analyst Zifo

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