South San Francisco, CA30+ days ago
Preferred Qualifications: • Experience leading discovery research programs from early-stage research through candidate selection • Knowledge of current therapeutic landscape in dermatology and medical aesthetics • Experience with novel therapeutic modalities (cell therapy, genetic medicine, precision medicine, local delivery technologies, etc.) • Experience with IND submission and preclinical data package generation • Deep expertise in cutaneous biology with demonstrated experience in developing complex ex vivo human skin/hair follicle assays and in vivo models of skin/hair disorders • Familiarity with data-driven discovery approaches, including integration of genetic or multi-omics insights • Experience building and managing research projects with proven success in project execution in a multi-disciplinary team environment • High degree of organizational skills, attention to detail, and critical thinking, with ability to prioritize work and meet target timelines • Excellent interpersonal and communication skills, with the ability to drive cross-site collaboration in a matrixed research environment. Research Development & Execution: • Help identify novel targets based on human causal biology and validate their contribution to skin quality and hair disorders using relevant in vitro, ex vivo, and in vivo models • Guide the design, optimization, and implementation of preclinical models that capture translational biology, integrating insights from human tissue profiling data • Design and implement flow schemes to characterize potential therapeutics for effects on cutaneous biology, leveraging both internal and external resources • Partner with the Immunology in vivo pharmacology team to execute critical experiments • Work with a cross-functional team to generate comprehensive data packages that advance novel therapeutic approaches and support Go/No Go decision-making.