Senior Manager / Site Director, Clinical Operations Adams ClinicalSenior Manager / Site Director, Clinical OperationsWatertown, MassachusettsThe Senior Manager provides site-level leadership and operational ownership of clinical operations, with direct responsibility for staff management, study execution, regulatory compliance, strategic alignment with network leadership, and ensuring high-quality trial execution that meets sponsor expectations and business objectives. The Site Director assumes the same core clinical operations responsibilities while providing broader site-wide leadership through additional support of the Clinical Science function, clinician development, cross-functional performance, and integration of clinical science with site operations in partnership with Clinical Science leadership.
USA - Senior Manager, Integrated Clinical Trial Data Process Excellence and Delivery The Fountain Group LLCUSA - Senior Manager, Integrated Clinical Trial Data Process Excellence and DeliveryCambridge, MARemote$86.67–$89.66 / hourFacilitate cross-functional workshops and subject matter expert interviews to gather requirements, document process steps, and clarify roles and handoffs. Provide process-development expertise within assigned scope and escalate governance, prioritization, and approval matters to accountable stakeholders.
Senior Manager, Clinical Operations - GI Iterative HealthSenior Manager, Clinical Operations - GICambridge, MA$140,000–$165,000 / yearAs the Senior Manager, Clinical Operations- GI at Iterative Health you will serve as a strategic advisor to sponsors, CROs, and research sites, translating operational challenges into scalable solutions that improve study execution, accelerate activation timelines, and drive patient recruitment performance. By combining deep clinical research expertise with a consultative approach, this individual will help strengthen sponsor relationships, elevate site performance across the network, and contribute directly to Iterative Health's mission of bringing innovative therapies to patients faster.
Clinical Research Nurse, Translational Neuroscience Center (TNC) Boston Children's HospitalClinical Research Nurse, Translational Neuroscience Center (TNC)Brookline, MA$83,241.60–$133,192.80 / yearIn collaboration with Principal Investigators and other study team members, the Clinical Research Nurse (CRN) will be responsible for the implementation of clinical research studies supported by the TNC including both clinical research nursing and study project management activities. In addition to providing and coordinating clinical research care and safety for study participants, the CRN will have a central role in study project management assuring ongoing regulatory compliance, integrity of protocol implementation, and accuracy of data collection.
Clinical Trials Project Manager Senior Brigham and Women's HospitalClinical Trials Project Manager Seniormassachusetts, MA$78,936–$128,928.80 / yearThey will provide day to day guidance for investigators and study teams on the implementation of study protocols and will be the key liaison with the study sponsor, CRO, funding agency, central vendors, as well as all levels of study staff at the NCRI to ensure the smooth operation of assigned multi-center clinical trials. The NCRI employs physician clinical researchers, research nurse, project managers, data managers, SAS programmers, systems analysts, grants managers and administrative assistants dedicated to planning and implementing clinical trials.
Clinical Research Program / Project Manager Mass General BrighamClinical Research Program / Project ManagerBoston, Massachusetts$63,252.80–$102,596 / yearEssential Functions:-Leads program and project teams and coordinates and delegates cross-project initiatives.-Conducts research, manages and analyzes data in systems, and develops reports and presentations to support programs.-Identify potential risks, issues, and challenges associated with programs and develop mitigation strategies to minimize impact.-Monitor program progress and proactively address deviations from plans, timelines, or budgets.-Manages the program budget, ensuring responsible allocation of resources and adherence to financial guidelines. The Massachusetts General Hospital Ammon-Pinizzotto Center for Women’s Mental Health (CWMH) provides clinical consultation and research regarding the course and treatment of psychiatric disorders during pregnancy and the postpartum period.
Senior Manager, Clinical Program Quality and Excellence (Oncology) 3316 Takeda Development Center AmericasSenior Manager, Clinical Program Quality and Excellence (Oncology)MassachusettsFacilitate investigations into significant quality issues, scientific misconduct and serious breach of GCP; facilitate identification of root cause and development of appropriate corrective and preventive actions; track actions and confirm effectiveness; ensure reporting of potential or confirmed violations to regulatory authorities. Provides quality assurance oversight of the global clinical research programs in Research and Development (R&D), Plasma Derived Therapy (PDT), Vaccines Business Unit (VBU), Oncology Business Unit (OBU) and Global Medical Marketed Products Development (MPD) with the overall goal of inspection readiness.
Clinical Research Program Manager Brigham and Women's HospitalClinical Research Program ManagerBoston, MA$78,936–$128,928.80 / yearThe framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission.
Senior Clinical Research Program Manager Brigham and Women's HospitalSenior Clinical Research Program ManagerBoston, MA$78,936–$128,928.80 / yearWorking closely with the RII Division Chief, the Divisional Director of Epidemiology and Clinical Sciences Research, Divisional Principal Investigators (PIs), and in partnership with other RII Research Managers/Administrators, and reporting to the RII Senior Administrative Director, the Senior Clinical Research Program Manager provides high-level administrative support and operational oversight for the division's clinical trial portfolio. The position collaborates closely with the RII Clinical Operations/Program Director and Research Administrative Managers to ensure divisional clinical trials align with operational protocols, resource allocations, and institutional policies.
Senior Manager, Clinical Operations - GI Iterative Scopes Inc.Senior Manager, Clinical Operations - GICambridge, MAAs the Senior Manager, Clinical Operations- GI at Iterative Health you will serve as a strategic advisor to sponsors, CROs, and research sites, translating operational challenges into scalable solutions that improve study execution, accelerate activation timelines, and drive patient recruitment performance. By combining deep clinical research expertise with a consultative approach, this individual will help strengthen sponsor relationships, elevate site performance across the network, and contribute directly to Iterative Health's mission of bringing innovative therapies to patients faster.
Clinical Research Assistant Adams ClinicalClinical Research AssistantWatertown, MassachusettsWorking under the direct supervision of a CRC II, CRC III, or Site Manager, the RA assists with operational, administrative, and participant-facing tasks to ensure studies run smoothly and in accordance with ICH-GCP, regulatory requirements, and protocol guidelines. Assist with investigational product (IP) accountability tasks as needed and where applicable, gaining exposure to IP handling, tracking, and documentation under the direct supervision of CRC staff, while ensuring adherence to protocol and site SOPs.
Senior Clinical Research Project Manager Mass General BrighamSenior Clinical Research Project ManagerBoston, MassachusettsIn this role, you will oversee all aspects of study planning and execution, including timelines, budgets, and data management; lead a team of clinical research professionals, which may include research nurses, clinical research coordinators, data analysts, contract research organizations (CROs), and external vendors, to ensure deliverables are met; and collaborate with internal and external stakeholders to ensure studies are conducted efficiently and in compliance with Good Clinical Practice, FDA regulations, and IRB policies. Success in this role requires strong leadership and organizational skills, excellent communication skills, the ability to problem-solve with good judgment, a comprehensive understanding of clinical research processes, and the ability to proactively identify and mitigate risks and resolve operational challenges while driving process improvements.
Clinical Research Associate/Coordinator I Brigham and Women's HospitalClinical Research Associate/Coordinator IBoston, MA$20.16–$29.01 / hourThe Clinical Research Associate/Clinical Research Coordinator I (CRA/CRC I) works under general supervision to enroll eligible patients to clinical research protocols and manage all aspects of data collection and submission for multiple cancer studies. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success.
Clinical Contracts Manager, Cambridge, MA Isomorphic Labs LimitedClinical Contracts Manager, Cambridge, MACambridge, MAOperating at an organizational level, this role drives vendor selection, supports negotiation of Master Service Agreements (MSAs) and Clinical Trial Agreements (CTAs), and manages vendor related study budgets and contract lifecycle activities. By harnessing AI's powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world's most devastating diseases.
Clinical Study Operations Manager Beacon Biosignals IncClinical Study Operations ManagerBoston, MARemote$90,000–$110,000 / yearAs such, we''re always seeking new contributors whose work demonstrates an avid curiosity, a bias towards simplicity, an eye for composability, a self-service mindset, and - most of all - a deep empathy towards colleagues, stakeholders, users, and patients. As a Clinical Study Operations Manager within the Clinical Study Operations team, you will be responsible for ensuring the successful operational delivery of Beacon's clinical studies, from startup through close-out.
Clinical Trial Manager Kymera TherapeuticsClinical Trial ManagerWatertown, MA$115,000–$200,000 / yearHaving advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Work closely with translational medicine team to ensure appropriate incorporation of bioanalytical sampling plan into clinical protocols and relevant data output of the trial is provided to functional groups for review.
Lead Clinical Data Manager Karwell TechnologiesLead Clinical Data ManagerCambridge, MACollaborate with cross-functional teams including Biostatistics, Clinical Operations, Safety, and Regulatory to ensure alignment of data management strategies with overall clinical development goals. Develop and implement data management plans, case report forms (CRFs), edit checks, and data validation plans in alignment with study protocols and regulatory requirements.
Clinical Research Finance Specialist Iterative Scopes Inc.Clinical Research Finance SpecialistCambridge, MAThe Clinical Research Finance Specialist is a critical member of Iterative Health's growing Finance team, partnering closely with the Research Finance Manager to own end-to-end accounts receivable operations across sponsor-funded clinical studies and internal research sites. This role sits at the intersection of finance and clinical research - ensuring accurate billing, timely cash application, and prompt resolution of outstanding balances across a complex, multi-site research environment.
Senior Clinical Research Associate (level dependent on experience) CTISenior Clinical Research Associate (level dependent on experience)Boston, MassachusettsFor that reason, we treat our team members with the respect they deserve, and our numbers show it: We support career progression – We believe in promoting from within and we have a structured mentoring program and program for recent graduates to provide the support employees need to move forward. To help support the unique job functions of our CRAs, we have a dedicated training department that offers ongoing therapeutic training sessions from our world-class medical directors, and an experienced and supportive management team that is there to offer continual guidance.
Clinical Research Project Manager Brigham and Women's HospitalClinical Research Project ManagerBoston, MA$63,252.80–$102,596 / yearWe envision this project manager serving as the operational lead for our research portfolio, overseeing study startup, regulatory compliance, budget and contract coordination, monitoring and audit readiness, and day-to-day project management across multiple active protocols. Our research team at the Brigham and Women's Hospital includes physician investigators, medical imaging physicists, research fellows (fully trained cardiologists), a data analyst, and ten research assistants (who recruit participants for our research projects).