Dr. Guzman's research focuses on spatial transcriptomics, brain banking, and clinicopathologic correlation in disorders including Alzheimer disease, hippocampal sclerosis-associated epilepsy, autoimmune neurologic disease, and related neurodegenerative conditions. The program is a partnership between the Neurology Department and interested patients and families to obtain an autopsy shortly after death to study the brain, spinal cord, and other tissues of individuals with memory disorders.