Senior Clinical Program Manager, Clinical Operations Revolution Medicines, Inc.Senior Clinical Program Manager, Clinical OperationsRedwood City, CA$164,000–$205,000 / yearThe company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Ability to analyze operational data, contribute with a mind on quality, timeliness and fiscal responsibility, make and drive decisions, multi-task, prioritize tasks, anticipate challenges, and execute on goals as a member of an interdisciplinary team.
Clinical Trial Manager, Clinical Operations CytomX TherapeuticsClinical Trial Manager, Clinical OperationsSouth San Francisco, CaliforniaWorks directly with study team and/or vendors on development of study documents, plans and manuals including but not limited to: protocol and amendments, investigator brochure, informed consent form, annual reports, clinical study report, pharmacy manual, laboratory manual and internal data review plan. CytomX has a broad pipeline, which comprises seven therapeutic candidates across multiple treatment modalities including antibody-drug conjugates (“ADCs”), T-cell engaging bispecific antibodies (“TCBs”), and immune modulators such as cytokines and checkpoint inhibitors (“CPIs”).
Senior Clinical Program Manager, Clinical Operations Revolution MedicinesSenior Clinical Program Manager, Clinical OperationsRedwood City, CaliforniaThe company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Ability to analyze operational data, contribute with a mind on quality, timeliness and fiscal responsibility, make and drive decisions, multi-task, prioritize tasks, anticipate challenges, and execute on goals as a member of an interdisciplinary team.
Vendor & Budget Manager, Clinical Operations Epic-BioVendor & Budget Manager, Clinical OperationsSouth San Francisco, CA$135,000–$145,000 / yearManage all existing clinical vendors, requiring contract oversight and coordination with legal and internal teams, budget and PO oversight alongside internal finance and accounting, while partnering with the CTM and other Clinical Operations team members to ensure vendor deliverables align with study needs. This is a highly cross-functional role partnering closely with Clinical Operations, Finance, Legal, and external vendors to ensure studies are executed efficiently and in alignment with timelines, scope, and budget.
Trial Master File Sr. Manager, Clinical Operations Maze TherapeuticsTrial Master File Sr. Manager, Clinical OperationsSouth San Francisco, CA$175,000–$215,000 / yearOur clinical pipeline is anchored by two small molecule programs: MZE829, an APOL1 inhibitor for patients with APOL1‑mediated kidney disease, and MZE782, which targets genetic drivers of disease in phenylketonuria (PKU) and chronic kidney disease. This role is ideal for an experienced TMF professional who thrives in a fast-paced biotech environment, enjoys building processes from the ground up, and is passionate about developing high-quality, inspection-ready Trial Master Files.
Senior Project Manager, Clinical Operations Maze TherapeuticsSenior Project Manager, Clinical OperationsSouth San Francisco, CA$181,000–$221,000 / yearThis position combines portfolio-level project management with strategic operational initiatives, partnering closely with Clinical Operations Study Leads, Oversight Directors, and cross-functional teams to support the successful execution of multiple clinical pharmacology studies, early-phase studies, Phase 2 studies, and Phase 3 development programs, In this role, you will facilitate cross-functional planning and communication, coordinate complex study execution activities across the clinical portfolio, and oversee key Clinical Operations initiatives that strengthen organizational capabilities, improve processes, and drive operational excellence. Clinical Operations Project Management Partner with Clinical Operations Study Leads and Oversight Directors to coordinate project management activities across multiple Phase 1, clinical pharmacology, Phase 2, and Phase 3 studies, ensuring alignment of timelines, milestones, dependencies, and cross-functional deliverables.
Associate Director, Clinical Operations Structure Therapeutics IncAssociate Director, Clinical OperationsSouth San Francisco, CA$186,000–$220,000 / yearCross-Functional Collaboration: Work closely with Preclinical, Biostatistics, Data Management, Clinical Supplies, Safety/PV, and Medical Affairs teams to ensure seamless study execution and IMP accountability, including sample management and study plan reviews. The company's platform combines the latest advancements in visualization of molecular interactions, computational chemistry, and data integration to design orally available, superior small molecule medicines that overcome current limitations of biologic and peptide drugs.
Senior Manager/Director Clinical Operations Lycia TherapeuticsSenior Manager/Director Clinical OperationsSouth San Francisco, CARemote$169,000–$198,000 / yearAbility to manage in a consensus environment through teamwork, trust and shared expectations, influencing strategic direction of complex global clinical operations issues, solicit information, listen well, persuade others, make important decisions and shape outcomes. Build, develop and train internal staff and external vendors, structure department for enhancing efficiency, and create a highly engaged work environment for attracting and retaining highly qualified clinical operations professionals.
Senior Manager, Records Management - Clinical Operations Arcus Biosciences, Inc.Senior Manager, Records Management - Clinical OperationsHayward, CARemote$155,000–$170,000 / year8+ years of related industry experience at a Sponsor or CRO plus 3+ years of Clinical TMF management is required, (extensive experience with Veeva Vault and Veeva applications is strongly preferred). Effectively manage resources to ensure appropriately skilled team are assigned to support Records Management Organization, including participating in hiring, training, mentoring and periodically assessing performance during the bi-annual performance review periods.
Associate Director, Clinical Operations Compliance & Training Revolution Medicines, Inc.Associate Director, Clinical Operations Compliance & TrainingRedwood City, CA$186,000–$233,000 / yearThe company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies.
Senior Director, Clinical Operations, Global Clinical Vendor Contracts & Budgets Revolution MedicinesSenior Director, Clinical Operations, Global Clinical Vendor Contracts & BudgetsRedwood City, California$244,000–$305,000 / yearThe leadership role ensures alignment with strategic objectives, regulatory requirements, and study timelines as well as bringing deep expertise in managing complex trials, contract negotiations, budget development, risk management, and cross-functional collaboration to contribute to the highest quality with on time delivery of RevMed’s clinical studies. A member of the Clinical Operations team Leading the Contracts and Outsourcing for all vendor relationships within Clinical Development, the Sr Director Global Vendor Outsourcing will lead the strategic identification and selection process with the teams for vendors and CROs, including scope specifications for clinical programs, and will work closely with the Sr.
Senior Director, Clinical Operations Pliant Therapeutics, Inc.Senior Director, Clinical OperationsSouth San Francisco, CA$289,000–$320,000 / yearWe believe our platform may be broadly applicable across multiple disease areas including delivery of drug payloads to cells utilizing integrin receptor-binding molecules as tissue-specific delivery and internalization mechanisms. Currently, Pliant is conducting a Phase 1 study of PLN-101095, a small molecule, dual-selective inhibitor of vß8 and vß1 integrins, that has shown encouraging clinical activity in the development of a treatment of immune checkpoint resistant solid tumors.
Oversight Director, Clinical Operations Maze TherapeuticsOversight Director, Clinical OperationsSouth San Francisco, CA$232,000–$283,000 / yearCross-functional Collaboration Collaborate closely with Clinical Science, Regulatory Affairs, Data Science, Pharmacovigilance, Biometrics, Medical Monitoring, Clinical Supply, CMC, Tech Ops, Finance, and other cross-functional partners to influence asset strategy and drive successful program execution. Clinical Development & Portfolio Collaboration Provide strategic and operational direction across an assigned development asset spanning CKD and PKU clinical programs, ensuring alignment between clinical development strategy and operational execution from protocol development through study closeout and regulatory readiness.
Director, Clinical Operations Maze TherapeuticsDirector, Clinical OperationsSouth San Francisco, CA$232,000–$283,000 / yearGlobal Phase 3 Study Leadership Serve as the operational Study Lead for a global pivotal Phase 3 study (North America, South America, Africa, and Europe), maintaining responsibility for successful execution from protocol development and start-up through enrollment, database lock, study closeout, submission support, and inspection readiness. Data Quality, Compliance & Regulatory Readiness Maintain a continuous state of inspection readiness across the study, including safety reporting, TMF completeness and quality, essential documentation, evidence of vendor oversight, issue and CAPA management, and audit preparedness, in close partnership with Quality Assurance (QA).
Director of Clinical Operations - SoCal BlueSprigDirector of Clinical Operations - SoCalSan Bruno, California$115,000–$132,000 / yearThis role includes oversight of all elements of assigned market; including implementation, day- to-day oversight of key workflows on behalf of BlueSprig, providing strategic and tactical leadership, counsel, leadership, and coaching to center leaders to accomplish organizational objectives, including but not limited to clinical quality, compliance, revenue, client satisfaction, business development and growth objectives. Guiding, organizing, and monitoring the operations and clinical services provided in market, overseeing 6-10 centers within a defined geographic market; ensuring the efficiency, stability and the highest level of quality service is consistent enterprise-wide.
Senior Director, Clinical Operations BigHat BiosciencesSenior Director, Clinical OperationsSan Mateo, CaliforniaClinical Document Generation: Manage the preparation and lifecycle of key clinical documents, including protocols, informed consent forms, investigator brochures, clinical study reports, and regulatory submissions, ensuring accuracy, timeliness, and compliance with applicable guidelines. Translational Biomarker Support: Partner closely with the Translational Biomarker team to ensure clinical operations infrastructure supports biomarker sample collection, handling, and logistics across all trial sites.
Regional Clinical Operations Manager JumpstartMDRegional Clinical Operations ManagerBurlingame, CaliforniaWe are seeking an individual with a proven track record in multi-site operations leadership, a deep commitment to exceptional member experience, and the leadership instincts to develop and inspire Clinician Managers across our Bay Area region. Are you an experienced operations leader with a passion for healthcare and wellness — someone who thrives in a fast-paced, multi-site environment and knows how to develop great managers, drive results through data, and create a culture of accountability and excellence?
Associate Director, Clinical Operations Compliance & Training Revolution MedicinesAssociate Director, Clinical Operations Compliance & TrainingRedwood City, CaliforniaThe company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies.
Director, Clinical Trial Operations Nkarta, Inc.Director, Clinical Trial OperationsSouth San Francisco, CA$220,000–$270,000 / yearDevelop, review, and approve clinical study plans, manuals, presentations, and other study documents (country/site specific ICF's, site facing documents and tracking tools), assist with user acceptance testing, sample and product tracking, and other activities as needed. The Director of Clinical Trial Operations works closely with the Executive Director of Clinical Operations and the clinical and leadership teams to lead the strategic planning, execution, and delivery of one or more clinical trials or programs.
Vp/Senior Director, Clinical Operations NewLimitVp/Senior Director, Clinical OperationsSouth San Francisco, CALearn more at: https://www.newlimit.com/careers *This compensation and benefits information is based on Company's good faith estimate as of the date of publication and may be modified in the future. Disentangle the inevitable operational challenges that arise in trial execution - debugging recruitment, cross-border logistics, regulatory compliance, and staffing.