Senior Director, Outcomes, Value & Access Kymera TherapeuticsSenior Director, Outcomes, Value & AccessWatertown, MA$235,000–$330,000 / yearHaving advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. The ideal candidate is an experienced HEOR leader with deep immunology expertise (dermatology and/or respiratory strongly preferred), a proven track record preparing for and supporting launches, and significant experience engaging national and regional payer stakeholders.
Sr. Medical Director, Medical Affairs (Alixorexton) Alkermes PlcSr. Medical Director, Medical Affairs (Alixorexton)Waltham, MAThe incumbent will need to understand the business strategies and drivers underlying our Alixorexton program, translating those drivers into strategies and data generation and communication plans that contribute to a successful product launch, and ensure alignment of Alixorexton activities across our neuroscience portfolio. In 2024 and 2025, we were certified as a Great Place to Work in the U.S. and named one of Massachusetts' Top Places to Work by the Boston Globe, a Best Place to Work in Greater Cincinnati by the Cincinnati Business Courier and recognized as a Best Place to Work in BioPharma by Fortune Magazine.
Executive Director, Head of PV Operations Oversight 3316 Takeda Development Center AmericasExecutive Director, Head of PV Operations OversightBoston, MassachusettsThis role is accountable for the operational performance of global case processing, Individual Case Safety Report (ICSR) management, regulatory reporting, tracking of market research / patient support programs (MR / PSP), performing PV review and approval of digital assets and social media programs before launch, and oversight of pharmacovigilance service providers. Oversee pharmacovigilance activities related to case intake, case processing, medical coding, triage, quality review, Individual Case Safety Reports (ICSRs), regulatory reporting, market research programs, patient support programs, and Takeda-sponsored digital assets and social media initiatives.
Senior Director, Global Heva Neurology, Early And Pipeline Assets SanofiSenior Director, Global Heva Neurology, Early And Pipeline AssetsCambridge, MA$206,250–$297,916.66 / yearDemonstrated proficiency in AI and digital tools for health economics research, including experience with AI-powered analytics platforms, machine learning applications for evidence synthesis, and digital data management systems; proven ability to leverage emerging technologies (such as generative AI tools and automated data analysis) to enhance research efficiency and drive innovation in HEOR evidence generation. Grounded in Scientific Excellence with Relevance and deep technical expertise, we embrace Innovation in Action to transform how we research and deliver Impact for People, creating meaningful outcomes for patients, the healthcare ecosystem, and our colleagues who make it all possible.
Senior Director, Global HEVA Neurology, Early and Pipeline Assets SanofiSenior Director, Global HEVA Neurology, Early and Pipeline AssetsCambridge, MA$206,250–$297,916.66 / yearDemonstrated proficiency in AI and digital tools for health economics research, including experience with AI-powered analytics platforms, machine learning applications for evidence synthesis, and digital data management systems; proven ability to leverage emerging technologies (such as generative AI tools and automated data analysis) to enhance research efficiency and drive innovation in HEOR evidence generation. Grounded in Scientific Excellence with Relevance and deep technical expertise, we embrace Innovation in Action to transform how we research and deliver Impact for People, creating meaningful outcomes for patients, the healthcare ecosystem, and our colleagues who make it all possible.
Sr. Director, Global Brand & Portfolio Management CSL Behring LLCSr. Director, Global Brand & Portfolio ManagementWaltham, MA$287,000–$352,000 / yearOversees and guides continued global launch planning for aTIVc, including maximizing the portfolio opportunity across Fluad and aTIVc, refining the launch sequencing strategy, advancing business cases for key investments, and leveraging the Glocal brand marketing model (global to local division of activities) to drive efficiencies. Working in close partnership with R&D and cross-functional stakeholders, the role ensures alignment from research through commercialization, advances high-value strategic investments, and drives portfolio decisions that maximize mid- to long-term growth, value creation, and public health impact.
Rheumatology (Senior) Medical Director - Medical Affairs Swedish Orphan Biovitrum ABRheumatology (Senior) Medical Director - Medical AffairsWaltham, MA$224,000–$290,000 / yearDevelop and foster strong collaborative relationships with internal partners, including Regulatory Affairs, Clinical Operations, Market Access, Medical Information, Pharmacovigilance, Sales, and Marketing, and provide medical insight and product- and disease-state expertise to meet business objectives. Develop a US evidence generation strategy to address stakeholder (HCPs, payers, and patients) needs (including product differentiation, health outcomes), collaborating with HEOR and global partners.
Associate Director or Director of Pharmacovigilance Operations Compass Therapeutics IncAssociate Director or Director of Pharmacovigilance OperationsBoston, MA$175,000–$250,000 / yearManage scaling of PV operations, systems and processes, safety and vendor governance, risk management, internal and external partnerships, audit and inspection readiness, for commercial readiness in support of compliant regulatory filings and commercial launch; as detailed below. Establish and monitor rigorous metrics-based PV Key Performance Indicators (KPIs) to assess vendor performance, quality, regulatory compliance, timeliness, and data integrity ensuring high-quality case management, inspection readiness, and delivery of contracted services.
Scientist, Translational Research Science, Haem R&D AstraZeneca PlcScientist, Translational Research Science, Haem R&DCambridge, MA$92,252–$138,378 / yearAs a Scientist, within the Translational Research Science Haem R&D team, you will be part of high-caliber team to design and deliver translational assays and data that steer clinical trials, sharpen pre-clinical decisions, and unlock new combinations across indications. With a robust pipeline across multiple cancer indications and a history of bringing new therapies to patients, we combine groundbreaking technology with an entrepreneurial spirit and a collaborative community that spans leading medical centers worldwide.
NewExecutive Director, Philanthropy, Newton-Wellesley Hospital Brigham and Women's HospitalExecutive Director, Philanthropy, Newton-Wellesley HospitalNewton, MA$220,000–$250,000 / yearThis role is accountable for setting fundraising strategy, driving innovation and growth, managing budgets and operational performance, leveraging data and metrics to inform decision-making, and ensuring compliance with all Mass General Brigham Development Office and institutional policies related to fundraising, prospect management, gift administration, and performance management. The Executive Director leads and develops a high-performing fundraising team, cultivates strategic partnerships with hospital leadership, physicians, volunteers, donors, and community stakeholders, and advances a strong culture of philanthropy throughout the organization.
Clinical Research Director - Immunology and Inflammation SanofiClinical Research Director - Immunology and InflammationCambridge, MA$206,250–$343,750 / yearThe Clinical Research Director (CRD), Immunology and Inflammation Therapeutic Area, Solid Organ Transplant focus, is responsible for the development, execution and reporting of clinical trials in support of the registration of a product, directly reporting to the Clinical Lead in charge of the clinical strategy. In addition, the CRD is responsible for the development of abbreviated protocol and clinical protocol, participates to the review process for protocols, study reports, labeling, and contributes/supports interactions with regulatory agencies and ethics committees.
Global Development Medical Director, Late Respiratory and Immunology Clinical Development AstraZeneca PlcGlobal Development Medical Director, Late Respiratory and Immunology Clinical DevelopmentBoston, MA$241,613–$362,420 / yearIn the BioPharmaceuticals Research & Development, Late-stage Development, Respiratory & Immunology function you will work in a truly international working environment, with opportunities to meet and discuss with key external experts, other medical colleagues and experts in basic science, as well as commercial and regulatory functions. As a Global Development Medical Director, you will support the clinical project team and assist the Global Clinical Project Leader and Global Clinical Head with the design & interpretation process, establishing clear design objectives for clinical programs and studies.
Director, AI/ML MIDD Oncology Clinical Pharmacology, Modeling and Simulation GSK plcDirector, AI/ML MIDD Oncology Clinical Pharmacology, Modeling and SimulationWaltham, MA$188,100–$313,500 / yearBasic Qualifications: We are looking for professionals with these required skills to achieve our goals: A PhD in Quantitative Clinical Pharmacology and Pharmacometrics (e.g., pharmacology, engineering or statistics) or relevant Life Sciences discipline, and experience in using modelling/simulation to solve practical problems in industry or academia. Drug Design, Drug Development, Drug Discovery Process, Drug Discovery Research, Medication Safety, Molecular Modeling, Pharmaceutical Regulatory Compliance, Pharmaceutical Sciences, Pharmacodynamics, Pharmacokinetics, Pharmacology, Pharmacometrics, Pharmacovigilance, Study Design, Target Validation.
Executive Director, Oncology Translational Medicine, Clinical Pharmacology Modeling and Simulation GSK plcExecutive Director, Oncology Translational Medicine, Clinical Pharmacology Modeling and SimulationWaltham, MAWe have an exciting opportunity at GSK for a highly motivated and experienced Executive Director to join our team supporting the Oncology Clinical Pharmacology Modelling and Simulation (CPMS) department within Oncology Translational Medicine. This role focuses on delivering CPMS excellence to research and development programs, helping to accelerate the development of innovative oncology therapies by ensuring they reach the right patients, at the right dose, and at the right time.
Director/Sr. Director, Clinical Operations - Oncology Programs Frontier Medicines CorpDirector/Sr. Director, Clinical Operations - Oncology ProgramsBoston, MAFrontier Medicines is seeking two experienced Clinical Operations leaders, at the Director or Senior Director level, to drive the operational strategy and execution of our oncology programs as they advance through clinical development. The ideal candidate brings deep oncology experience, strong global study oversight, and the ability to influence stakeholders, anticipate challenges, and deliver results in a dynamic biotech environment.
NewDirector, Clinical Operations Asset Lead GSK plcDirector, Clinical Operations Asset LeadWaltham, MA$189,750–$316,250 / yearWorking in close partnership with clinical, biostatistics, and functional experts, the COAL drives informed decision‑making, provides strategic leadership to Study Delivery Teams, and ensures high‑quality, on‑time delivery-while retaining full accountability for overall asset outcomes. Analytical Thinking, Business Acumen, Change Management, Clinical Research, Clinical Trial Designs, Communication, Decision Making, Fostering Collaboration, Influencing Without Authority, Leadership, Matrix Leadership, Mentorship, People Management, Risk Management, Strategic Thinking.
Principal Scientist (Director), Translational Medicine - Infectious Diseases Merck & Co IncPrincipal Scientist (Director), Translational Medicine - Infectious DiseasesBoston, MA$260,300–$409,700 / yearPrimary responsibilities for the Principal Scientist include the following: Working with basic science teams on specific diseases and therapeutic areas, providing clinical expertise for identification and validation of novel targets, including the design of preclinical and clinical experiments to validate targets and/or pathways, and leveraging this work for development of novel therapeutics. Translational Medicine is specifically responsible for: Contributing to the identification of novel targets by partnering with Discovery Sciences to bring a clinical perspective into the earliest stages of target identification and validation, and to execute clinical studies to evaluate the relevance of potential targets to human disease in order to justify full development.
Associate Director, Clinical Scientist CRISPR TherapeuticsAssociate Director, Clinical ScientistSouth Boston, MassachusettsThe Company has evolved from a pioneering research-stage organization into an industry leader, marking a historic milestone with the approval of CASGEVY® (exagamglogene autotemcel [exa-cel]), the world’s first CRISPR-based therapy, approved for eligible patients with sickle cell disease and transfusion-dependent beta thalassemia. The Company continues to expand its leadership in gene editing through the development of SyNTase editing, a novel and proprietary gene-editing platform designed to enable precise, efficient, and scalable gene correction.
Senior Clinical Research Associate (level dependent on experience) CTISenior Clinical Research Associate (level dependent on experience)Boston, MassachusettsFor that reason, we treat our team members with the respect they deserve, and our numbers show it: We support career progression – We believe in promoting from within and we have a structured mentoring program and program for recent graduates to provide the support employees need to move forward. To help support the unique job functions of our CRAs, we have a dedicated training department that offers ongoing therapeutic training sessions from our world-class medical directors, and an experienced and supportive management team that is there to offer continual guidance.
Translational Medicine Lead, Associate Director (Oncology) AstraZeneca PlcTranslational Medicine Lead, Associate Director (Oncology)Cambridge, MA$183,768.80–$275,653.20 / yearAccountabilities: Translational strategy ownership: Define and deliver an integrated translational and biomarker strategy for early development programs, aligning scientific goals, sample collection plans, assays, analyses, and decision points to accelerate learning and de-risk development. Early clinical leadership: Serve as Translational Medicine Lead for first-in-human studies, providing scientific leadership for protocol content, exploratory objectives, biospecimen plans, assay strategy, data review, and interpretation so study teams act on timely insights.