126 Results for

Clinical Scientist Jobs in Brookline, MA

Jobs

Boston, MA19 days ago

$40–$48 Per Hour
Contractor

A nationally recognized pediatric academic medical center is seeking an experienced Recruiter to support hiring across clinical research and related scientific roles. This individual will partner closely with hiring managers and research leadership to attract and hire top-tier talent supporting groundbreaking research initiatives.

New!

Boston, MAToday

$60–$96.28

Nurse Practitioners work alongside experienced clinical research professionals in an outpatient research setting, supporting a wide range of studies including drug and device trials, behavioral health research, tissue banks, and investigator-initiated protocols. Join the Clinical Research Center (CRC) at Boston Children's Hospital, a collaborative team dedicated to supporting innovative pediatric clinical research studies and trials.

New!

Weymouth, MAToday

In addition, the Research Nurse utilizes evidence-based nursing practice and has expertise in developing and coordinating a plan of care designed to meet the physical, psychological, and social needs of those cancer patients and their families undergoing therapy in a clinical research trial. Participates in Division of Nursing / Institute committees at the main DFCI Longwood campus, including, but not limited to, the monthly Research Nurse Practice Committee meeting.

New!

Boston, MAToday

The successful candidate will play a central role in leading our existing clinical trial infrastructure as well as the design, activation, and conduct of Phase I and first-in-human studies, contribute to the strategic growth of the Phase I program, and provide outstanding clinical care within a collaborative, mission-driven academic medical center. This role is ideal for an early- to mid-career physician-scientist who is prepared to assume increasing leadership in early-phase trial development while continuing to build an independent clinical and translational research portfolio.

Cambridge, MA30+ days ago

Full-time

The Scientist, is part of Analytical Development Starting Material Group and will be responsible for Develop, qualify and transfer GC, HPLC, UPLC and mass spectrometry based assays of starting materials, raw materials, intermediates and excipients to suppliers, CMOs and QC. Author and review method development and qualification reports and SOPs for test methods, as well as transfer / qualification protocols and reports related to critical starting materials / intermediates / excipients.

West Roxbury, Massachusetts30+ days ago

$40–$45 Per Hour

The employee will perform routine chemistry and urinalysis testing using automated instrumentation, including Beckman Coulter Urinalysis systems, Advanced Instruments Osmos, Polymedco OC80, and manual urinalysis and chemistry methods. The employee will perform routine chemistry testing using automated instrumentation, including Abbott Architect ci8200, Abbott Alinity, Advanced Instruments Osmos, Polymedco OC80, and manual chemistry methods.

Manchester, New Hampshire30+ days ago

Required Licensure/Certifications: Medical Laboratory Technician (MLT) or Medical Laboratory Science (MLS) or Medical Laboratory Technician (MLT-AMT) or Technologist/Specialist in Chemistry (C-ASCP) or International Technologist in Microbiology (M-ASCP) or Specialist in Hematology (SH-ASCP) or International Specialist in Microbiology (SM-ASCP) within 365 days. Dartmouth Hitchcock Medical Center and Clinics is home to the largest laboratory in NH, providing Pathology and Clinical Laboratory services to DHMC & Clinics physician practices, Dartmouth Health system member hospitals, and independent practices and hospitals throughout NH and VT.

Watertown, MA30+ days ago

$145,000–$215,000 Per Year

Partner closely with CMC colleagues and QA to (i) write or review test methods, SOPs, analytical data summaries (CoT/CoA), protocols, and technical reports, (ii) critically review, trend, and interpret analytical testing results, and (iii) support investigation of nonconformances (OOS/OOT results, deviations, etc.). Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions.

Cambridge, MA15 days ago

Full-time

The DECODE platform has been validated through four strategic partnerships with leading pharmaceutical companies—Bristol Myers Squibb, Genentech, Eli Lilly, and Pfizer—representing over $4.5 billion in disclosed total deal value and $185 million in upfront payments received to date. Experience with structural modeling tools and frameworks, including protein structure prediction (AlphaFold2/3, RoseTTAFold, ESMFold), structure-based design (ProteinMPNN, RFdiffusion), and/or graph neural networks operating on 3D protein coordinates (e.g.

Manchester, NH15 days ago

The Advanced Regenerative Manufacturing Institute (ARMl)IBioFabUSA is a Member-based non-profit, member-driven, public-private partnership with a mission to advance the bioeconomy and transform the future of human health. The ideal candidate will have experience with process development or early phase GMP manufacturing, aseptic techniques and operations within a controlled manufacturing environment, SOP/Batch Record drafting, and other aspects of contract manufacturing.

Waltham, MA30+ days ago

Full-time

You will report to the Associate Director, In Vitro Pharmacology and will work collaboratively in a matrixed environment to drive biologics discovery while supporting rapid decision-making in a fast-moving biotech setting. As Alloy Tx enters its next phase of growth, we are expanding our capabilities to include mechanistic studies that enhance preclinical development and further advance our translational research efforts.

Waltham, MA30+ days ago

Full-time

You will report to the Associate Director, In Vitro Pharmacology and will work collaboratively in a matrixed environment to drive biologics discovery while supporting rapid decision-making in a fast-moving biotech setting. Execute cell-based functional assays using high-throughput approaches in primary cells, immortalized reporter cell lines, and other disease-relevant cellular systems.

Natick, Massachusetts30+ days ago

$125,000–$155,000 Per Year

You will be responsible for: Analyzing scientific information to address microbiological, biological, and material science matters related to microbiological contamination root cause analysis, forensics, and product development, but also including a wide range of topics from medical devices and pharmaceuticals to consumer products and electronics. A strong theoretical and practical knowledge of various microbiological and biological assays (such as nucleic acid amplification tests, immunoassays, bacterial culture, protein quantification, and enzyme assays) and how material interactions can impact those techniques.

Cambridge, MA30+ days ago

$145,000–$177,000 Per Year

Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types. The Company is leveraging its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated, one-time, potentially curative genetic therapies.

Cambridge, MA30+ days ago

Develop and oversee ligand-binding immunoassays (ELISA, MSD, Luminex or similar platforms) for the detection of translated proteins and anti-drug or anti-protein antibodies, including screening, confirmatory, and neutralizing antibody assays in accordance with regulatory guidance. You will be a subject matter expert in nucleic acid and protein bioanalysis, working to generate critical data that informs decision-making across preclinical and clinical development.

Waltham, MA30+ days ago

We are looking for an experienced researcher to join our team as Principal Research Associate/Associate Scientist in the Molecular Assembly team, supporting our novel target identification and validation workflow in house. Excellent written and verbal communication skills, with the ability to document experiments in an organized and timely fashion and to present scientific data to coworkers.

Lexington, MA30+ days ago

$116,400–$140,000 Per Year

The Group’s efforts include developing software architectures and systems, bioinformatics tools, and AI algorithms to further the nation’s efforts in biomedical, health, chemical and biological defense, biosecurity, public and global health and warfighter performance. The position will involve leading the development of AI/ML models, data curation, planning and conducting field data collections, leading small programs, collaborating with other scientists and engineers, and communicating results both in written and oral form.

Watertown, MA30+ days ago

The ALS Therapy Development Institute (ALS TDI) is the world's leading nonprofit biotech focused exclusively on discovering and developing effective treatments for amyotrophic lateral sclerosis (ALS). This position is responsible for developing new animal models of ALS and performing preclinical pharmacology studies to evaluate the safety, efficacy, and mechanism of action of experimental drugs.

Boston, MA30+ days ago

Professional coding expertise in languages like Python and Go, proficiency in SQL, and experience with data visualization tools; skilled in using ML frameworks (TensorFlow, PyTorch) and implementing CI/CD, containerization, and version control best practices. Professional coding expertise in languages like Python and R, proficiency in SQL, and experience with data visualization tools; skilled in using ML frameworks (TensorFlow, PyTorch) and implementing CI/CD, containerization, and version control best practices.

Boston, Massachusetts30+ days ago

$60–$65 Per Hour

Agreeing to the Atrium Terms and Conditions, includes permission to use the email address and mobile phone number you provide during the application process or throughout the duration of your prospective or actual employment to notify you of job openings, profiles, articles, news, and other employment-related information, as well as to notify you of special promotions or additional products and services offered by us or our affiliates and partners. The Cell Hub is dedicated to the maintenance, tracking, quality control (QC), and production of cell biomass for critical assays and high throughput screenings, as well as the development of innovative techniques for large-scale production of complex cell models.

Boston, MA30+ days ago

We are seeking a Statistical Geneticist with expertise in whole genome sequencing (WGS), proteomics, and clinical outcomes analysis to advance our research in identifying novel therapeutic targets. The Cardiometabolic Research (CMR) Therapeutic Area of our client, focuses on the discovery of biologic, small molecule and genetic therapeutics for the treatment of cardiometabolic diseases and associated complications.

Boston, MA30+ days ago

$184,800–$196,350 Per Year

Experience deploying machine learning models in production environments, with a focus on cloud-based solutions such as GCP (BigQuery, GCS, Vertex AI, Composer), as well as workflow orchestration tools like Airflow, model tracking using MLflow, and containerization technologies like Docker. Using cutting-edge machine learning approaches, including deep sequence models, embeddings and multi-modal technologies, we aim to deliver a personalized and compelling experience for over 22 million active customers.

Cambridge, MA30+ days ago

$110,000–$125,000 Per Year

Its lead asset, zolucatetide (FOG-001), is a first-in-class, clinically validated direct inhibitor of the interaction between -catenin and the T-cell factor (TCF) family of transcription factors, implicated in millions of cancer cases annually, including in colorectal cancer, desmoid tumors, hepatocellular carcinoma and a range of other Wnt/-catenin-driven tumors. We are fiercely independent as a leader in defying the limitations of current therapeutic modalities, and interdependent as a team as we work collaboratively to shift drug discovery paradigms and provide patients with better treatment options.

Boston, MA30+ days ago

What You’ll Do: Design, build, deploy and refine large-scale machine learning models and algorithmic decision-making systems that solve real-world problems for customers. We value and rely on the collective voices of our employees, customers, community, and suppliers to help guide us as we build a better Wayfair – and world – for all.

Boston, MA10 days ago

Key ResponsibilitiesProducing innovative solutions driven by exploratory data analysis of complex and high-dimensional datasets; applying knowledge of statistics, machine learning, programming, data modeling, and advanced mathematics to generate and test hypotheses and interpret the results of experiments. Presenting at project and internal meetings; effectively conveying progress and asserting point of view; constructively discussing issues and providing facts; building credibility and trust by asking thoughtful questions and actively listening; running productive project meetings that advance problem-solving.

New!

Boston, Massachusetts6 days ago

Overview: Monte Rosa Therapeutics (MRT) seeks to recruit an experienced, creative and highly talented DMPK and ADME Scientist who is eager will assit in leading the discovery and development effort to grow the drug pipelines, as well as help lead external GxP compliance research efforts. Responsibilities: Work closely with the medicinal chemistry team, the Scientist Position will lead the Nonclinical Development efforts in troubleshooting and guidance to the discovery project team with a particular focus on optimizing properties for oral administration.

Natick, Massachusetts30+ days ago

$200,000–$300,000 Per Year

BEDFORD, MA15 days ago

Full-time

PharmaEssentia Innovation Research Center (PIRC) is expanding its drug discovery organization in the Greater Boston area and is seeking an experienced and highly motivated Senior or Principal Scientist with expertise in immunology, immuno-oncology, and translational pharmacology. Cross-Functional CollaborationWork effectively within multidisciplinary teams spanning biologics discovery, translational science, bioinformatics/data science, and external CRO collaborators.

BEDFORD, MA30+ days ago

Full-time

Founded in 2003 by a team of Taiwanese-American executives and renowned scientists from U.S. biotechnology and pharmaceutical companies, today we are listed on the Taipei Exchange (TPEx: 6446) and are expanding our global presence with operations in the U.S., Japan, China and Korea, along with a world-class biologics production facility in Taichung. The successful candidate will play a critical role in shaping therapeutic concepts and leading programs from early-stage discovery through IND-enabling studies, with significant influence over scientific strategy and key program-level decisions.

BEDFORD, MA30+ days ago

Full-time

Required QualificationsPhD in Immunology, Protein Engineering, Biochemistry, Molecular Biology, or a related field, with 7+ years of relevant industry experience in biologics or protein therapeutics discovery (4+ years for Senior Scientist level). The successful candidate will combine deep expertise in protein engineering, antibody and multispecific formats, and immuno-oncology biology with strong scientific leadership and hands-on execution.

Lexington, MA30+ days ago

$146,000–$164,000 Per Year

With a focus on developing differentiated product candidates that are designed to alter TGF- signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. The candidate will actively contribute to impactful preclinical research by developing and optimizing models of kidney fibrosis and evaluating the therapeutic potential of novel treatments modulating the TGF- ß pathway.

Cambridge, MA30+ days ago

$145,000–$177,000 Per Year

Key Responsibilities:Develop strategic plans and drive execution of analytical development activities for LNP DP programs, in alignment with program strategiesContribute to the development and refinement of the analytical control strategy, aligned with QTPP/CQAs and stage-appropriate development needs (early to late phase). Working as a member of a highly collaborative Technical Development / CMC organization, this individual will contribute to strategy and hands-on execution of method development to enable stage-appropriate development from early formulation/process development through clinical development stages, leveraging platform approaches when possible.

Ayer, MA30+ days ago

You will develop and optimize medical nutrition beverage and powder formulations using food science expertise while supporting clinical evidence, ingredient initiatives, IP protection, and GMP and food safety compliance. Provide scientific support to leadership across product development, clinical development, manufacturing, and new ingredient initiatives.

Boston, MA30+ days ago

$160,000–$220,000 Per Year

The actual salary offered will be based on a number of factors, including but not limited to the qualifications of the applicant, years of relevant experience, level of education attained, certifications or other professional licenses held, and if applicable, the location in which the applicant lives and/or from which they will be performing the job. This role involves significant hands-on experimental work to create oral dosage forms and innovative delivery systems to support pre-clinical and clinical development.

Watertown, MA30+ days ago

$145,000–$240,000 Per Year

PhD in organic/medicinal chemistry with 8+ years of experience or 10+ years of experience as a medicinal chemist/project leader in the biotech/pharmaceutical industry with a track-record of leading/contributing to research projects towards IND-track nomination. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions.

Boston, MA30+ days ago

Key Responsibilities:Performing a variety of moderate and highly complex and diagnostic laboratory testing under general supervision in the laboratory. Performing regularly scheduled quality control, preventative maintenance, and calibration of equipment according to laboratory guidelines.

Ayer, Massachusetts30+ days ago

Working Conditions / Physical Requirements: WORKING CONDITIONS: This position works in a food manufacturing environment and requires the ability to adhere to all GMP, Food Safety, workplace safety and security policies including wearing required personal protective equipment, as well hair net, beard net, etc. Overview: The Product Development Team supports the medical nutrition business by developing new and revising existing product formulations to meet target characteristics that will deliver positive patient outcomes through therapeutic nutrition.

Ayer, Massachusetts30+ days ago

Boston, Massachusetts30+ days ago

The Director Clinical Scientist will be responsible for scientific oversight, data integrity and quality of clinical trial(s) in support of the development strategy for programs within the Early- stage portfolio. Overview: The Director Clinical Scientist is an important and visible member of the Clinical Development team, working collaboratively with the Clinical operations lead and medical director.

Lexington, MA30+ days ago

$120,000–$170,000 Per Year

Leads, manages, and supports late-stage development, by identifying tasks, planning, monitoring progress of deliverables, and in terms of protocol and report generation in areas such as scale-down model qualification, process characterization, and scale-down model process validation studies. Leads and supports technology transfer activities at pilot plant and when necessary, preforms experiments him/herself, focusing scale-up platform process at scale and process improvements implementation, process characterization at scale and bills of materials as well as sampling plans.

Ayer, MA30+ days ago

Full-time

You will develop and optimize medical nutrition beverage and powder formulations using food science expertise while supporting clinical evidence, ingredient initiatives, IP protection, and GMP and food safety compliance. Skills: scientist, Food Science, Nutrition, product development experience from concept to commercialization in nutrition, food, beverage, supplement, nutraceutical, or biotech industries.

Lexington, MA30+ days ago

$120,000–$170,000 Per Year

Nearby Indianapolis is home to professional and college sports teams, the Indy 500, a growing art community and the world's largest children's museum--to name just a few reasons why this area is a great place to live. Known for its pivotal role in the American Revolution, Lexington offers visitors and residents alike a blend of historical landmarks, modern amenities, and a strong sense of community pride.

Boston, Massachusetts30+ days ago

$55–$60 Per Hour

Agreeing to the Atrium Terms and Conditions, includes permission to use the email address and mobile phone number you provide during the application process or throughout the duration of your prospective or actual employment to notify you of job openings, profiles, articles, news, and other employment-related information, as well as to notify you of special promotions or additional products and services offered by us or our affiliates and partners. Master’s or PhD in Chemical Engineering, Biochemical Engineering, Pharmaceutical Sciences, or a related discipline, with 3-5 years of industry experience, or equivalent years of education and experience; a PhD with 1-2 years of industry experience, or equivalent years of education and experience.

MA10 days ago

$235,000–$295,000

We are seeking individuals with 10+ years of postdoctoral experience who thrive in collaborative, agile environments and are passionate about advancing modeling and simulation approaches that drive meaningful impact for clients and patients. D. degree in a scientific discipline (pharmaceutical sciences, pharmacokinetics, mathematics, statistics, biomedical engineering or a related field) or Master's degree with relevant experience, or equivalent.

Cambridge, MA30+ days ago

$145,000–$175,000 Per Year

Provide scientific leadership and data science / (chem)informatics expertise towards, but not limited to, hit identification, targeted screening of Helical peptide library designs, hit prioritization, hit-to-lead progression using multi-objective optimization, new drug-target assessments, and advancing drug-pipeline projects towards the clinic. Reporting to the Associate Director of Cheminformatics, the candidate will work collaboratively with biologists and chemists, leveraging skills in data science and cheminformatics to enable hypothesis generation and data insights for advancing Fog preclinical drug discovery.

Framingham, MA30+ days ago

$92,000–$172,000 Per Year

In 2024 and 2025, we earned multiple workplace honors, including Built In's 100 Best Places to Work in Boston (both years), a Stevie Bronze Award for Great Employers, and recognition as a Great Place to Work in India. Headquartered just outside of Boston, Massachusetts, Definitive Healthcare operates across North America, Europe, and India, supporting a growing global client base of more than 2,400 customers since our founding in 2011.

Framingham, MA30+ days ago

$112,000–$210,000 Per Year

Burlington, MA30+ days ago

$140,000–$200,000 Per Year

This role represents a unique opportunity to expand that platform—both geographically and across new clinical areas—by establishing a broader infrastructure and network capable of managing device-based trials in partnership with hospitals, health systems, and external investigators. The role will work closely with executive leadership, physician leadership, and current clinical trials leadership, including the Vice President of Clinical Research and Chief of Clinical Operations and Research.

Cambridge, MA30+ days ago

$265,000–$305,000 Per Year

Cambridge Crossing, MA30+ days ago

$308,700–$374,075 Per Year

Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day. In collaboration with the Clinical Development Lead, designs and develops clinical plans and protocols with a strong strategic focus based on knowledge of asset/drug, disease area and relevant science in order to meet regulatory and disease strategy targets.

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Clinical Scientist Jobs in Brookline, MA

Healthcare Recruiter (Clinical & Research Talent) Workforce Connections

Nurse Practitioner, Clinical Research Center (temp) Boston Children's Hospital

RN Clinical Research Nurse / Dana-Farber Cancer Center South Shore Health

Medical Oncologist - Multiple Disease Site Options Tufts Medicine

Clinical/Development - Scientist, Analytical Development LanceSoft Inc

Medical Laboratory Scientist Aptive

Medical Laboratory Scientist III - Lab-South Dartmouth-Hitchcock Health

Principal Scientist, Analytical Development Kymera Therapeutics

Applied Machine Learning/AI Scientist Repertoire Immune Medicines

Scientist Advanced Regenerative Manufacturing Institute Inc

Associate Scientist, In Vitro Pharmacology Alloy Therapeutics

Scientist I/II, In Vitro Pharmacology Alloy Therapeutics

Scientist (Ph. D.) Exponent Inc.

Senior Scientist, Biomarkers Prime Medicine

Senior Scientist, Bioanalytical Sciences CEDENT

Principal Research Associate/Associate Scientist, Molecular Assembly TScan Therapeutics

Data Scientist (Lexington, MA, US) MIT Lincoln Laboratory

Scientist I or II, In Vivo Pharmacology, Drug Discovery ALS TDI

Machine Learning Scientist II - Multimodal AI Wayfair

Research Scientist – Cell Biologist, High Throughput Human Biology (Contract) Vertex Pharmaceuticals

Post Doctoral Scientist- Human Genomics and Translational Data Science Xenon7

Machine Learning Scientist III - Search & Recommendations Wayfair

Scientist I, Peptide Drug Discovery Parabilis Medicines

Machine Learning Scientist II - Search & Recommendations Wayfair

Genomic Scientist Boston Children's Hospital

Scientist, ADME & BioAnalytical Monte Rosa Therapeutics, Inc

Principal Scientist (M.D. or D.O.) Exponent Inc.

Senior / Principal Scientist, Immunology & Pharmacology PharmaEssentia U.S.A.

(Senior) Principal Scientist, Cell Therapy PharmaEssentia U.S.A.

Principal/ Senior Scientist – T Cell Engager & Multispecific Protein Engineering PharmaEssentia U.S.A.

Scientist, Kidney Fibrosis Keros Therapeutics

Sr Scientist, Analytical Development Prime Medicine

Product Development Scientist Upcoresolutions

Principal Scientist, Formulation Development (Small Molecules) Antares Therapeutics

Principal Scientist or Associate Director, Medicinal Chemistry Kymera Therapeutics

Medical Lab Scientist I - Overnight Boston Children's Hospital

Product Development Scientist Ajinomoto Cambrooke, Inc.

Product Development Scientist Ajinomoto Health & Nutrition North America, Inc.

Director, Clinical Science Monte Rosa Therapeutics, Inc

Sr/Principal Scientist - Upstream Process Development Genezen

Product Development Scientist MetaOption, LLC

Sr./Principal Scientist, Downstream Process Development Genezen

Biologics Drug Product Process Development Scientist (Contract) Vertex Pharmaceuticals

PKPD Principal Scientist Metrum Research Group

Senior Data Scientist, Chemical / Peptide Sciences Parabilis Medicines

Data Scientist Definitive Healthcare, US

Senior Data Scientist Definitive Healthcare, US

Vice President of Clinical Research Development Mangrove Management Partners

Senior Director, Clinical Sciences Parabilis Medicines

Sr. Clinical Trial Physician, Neuropsychiatry Bristol Myers Squibb

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