Takeda PharmaceuticalNewAssociate Medical Director, Clinical Science, NS TAU- Neurology/Psychiatry Takeda PharmaceuticalAssociate Medical Director, Clinical Science, NS TAU- Neurology/PsychiatryCambridge, MA$198,500–$311,850 / yearProvides leadership in meetings and negotiations with key opinion leaders, establishment of strategy for assigned compounds, and the direction of clinical scientists involved in developing documents required to outline the Company positions on research programs or regulatory applications (e.g. Contributes to the development and negotiation of clinical development plans for potential alliances and or in-licensing opportunities, interacts with upper management of potential partner/acquisition companies during DD visits and alliance negotiations and represents clinical science on internal assessment teams.
Takeda PharmaceuticalNewMedical Director, Clinical Science - Solid Tumor Takeda PharmaceuticalMedical Director, Clinical Science - Solid TumorBoston, MA$237,200–$372,790 / yearAssesses scientific, medical, and development feasibility, evaluating strategic fit with overall portfolio, evaluating complete or ongoing clinical trials, assessing regulatory interactions and future development plans, interacting with upper management of potential partner/acquisition companies during DD visits and alliance negotiations, and representing clinical science on internal assessment teams in conjunction with TPNA/TPEU/TPC. These responsibilities include leadership roles in meetings with the regulatory organizations or key opinion leaders, establishment of strategy for assigned compounds, and the direction of clinical scientists involved in developing documents required to outline the Company positions on research programs or regulatory applications (e.g.
Takeda PharmaceuticalNewAssociate Medical Director, Clinical Science, NS TAU Takeda PharmaceuticalAssociate Medical Director, Clinical Science, NS TAUCambridge, MA$198,500–$311,850 / yearProvides leadership in meetings and negotiations with key opinion leaders, establishment of strategy for assigned compounds, and the direction of clinical scientists involved in developing documents required to outline the Company positions on research programs or regulatory applications (e.g. Contributes to the development and negotiation of clinical development plans for potential alliances and or in-licensing opportunities, interacts with upper management of potential partner/acquisition companies during DD visits and alliance negotiations and represents clinical science on internal assessment teams.
Workforce ConnectionsHealthcare Recruiter (Clinical & Research Talent) Workforce ConnectionsHealthcare Recruiter (Clinical & Research Talent)Boston, MA$40–$48 / hourContractorA nationally recognized pediatric academic medical center is seeking an experienced Recruiter to support hiring across clinical research and related scientific roles. This individual will partner closely with hiring managers and research leadership to attract and hire top-tier talent supporting groundbreaking research initiatives.
AtriumNewClinical Research Medical Director (Part-Time) AtriumClinical Research Medical Director (Part-Time)Westport, 02790, MAThe organization partners with healthcare professionals, research teams, and sponsors to deliver high-quality clinical research while maintaining a strong focus on patient safety and regulatory compliance. Candidates who apply for roles through the Atrium website will be added to our candidate pool and may be considered for additional roles of a similar title.
South Shore HealthRN Clinical Research Nurse / Dana-Farber Cancer Center South Shore HealthRN Clinical Research Nurse / Dana-Farber Cancer CenterWeymouth, MAIn addition, the Research Nurse utilizes evidence-based nursing practice and has expertise in developing and coordinating a plan of care designed to meet the physical, psychological, and social needs of those cancer patients and their families undergoing therapy in a clinical research trial. Participates in Division of Nursing / Institute committees at the main DFCI Longwood campus, including, but not limited to, the monthly Research Nurse Practice Committee meeting.
Tufts MedicineMedical Oncologist - Multiple Disease Site Options Tufts MedicineMedical Oncologist - Multiple Disease Site OptionsBoston, MAThe successful candidate will play a central role in leading our existing clinical trial infrastructure as well as the design, activation, and conduct of Phase I and first-in-human studies, contribute to the strategic growth of the Phase I program, and provide outstanding clinical care within a collaborative, mission-driven academic medical center. This role is ideal for an early- to mid-career physician-scientist who is prepared to assume increasing leadership in early-phase trial development while continuing to build an independent clinical and translational research portfolio.
SanofiJunior Clinical scientist SanofiJunior Clinical scientistCambridge, MA$122,250–$176,583.33 / yearMain responsibilities: Contributes to preparation and/or review of any documents related to the studies and requiring a scientific background (abbreviated protocol/protocol/amended protocol, patient written information, presentations/communication to internal or external partners, study reports, committee charters, protocol registration form, redacted protocol, lay summary …). Contributes to definition of the centralized monitoring strategy in consistency with the planned statistical analysis and is involved in study data validation and review processes, support the CRD for the Clinical Case review (safety events reported to GPV or safety events of special interest), notably to anticipate and prevent last minute queries or backlog and smoothen the process.
CRISPR Therapeutics AGClinical Scientist/ Senior Clinical Scientist CRISPR Therapeutics AGClinical Scientist/ Senior Clinical ScientistSouth Boston, MA$125,000–$140,000 / yearSince its inception over a decade ago, CRISPR Therapeutics has transformed from a research-stage company advancing programs in the field of gene editing, to a company with a diverse portfolio of product candidates across a broad range of disease areas including hemoglobinopathies, oncology, regenerative medicine, cardiovascular and rare diseases. Familiarity with ICH, GCP, and relevant regulatory requirements, and strong analytical and strategic thinking skills, experience with interacting with medical monitors, development operations (preclinical, clinical operations, regulatory affairs, Quality Assurance) and clinical investigators.
Celldex Therapeutics IncSr. Clinical Scientist/Associate Director, Clinical Science Celldex Therapeutics IncSr. Clinical Scientist/Associate Director, Clinical ScienceNeedham, MA$133,579–$199,501 / yearAuthor (and/or work with external medical writers to develop) clinical documents including but not limited to clinical protocols/amendments, briefing documents, IND annual reports, Investigators Brochures, clinical study reports, scientific presentations including abstracts, posters and manuscripts. Ensure clinical data collection proceeds in a manner consistent with strategic objectives and regulatory requirements for reporting (i.e., collaborate with statisticians to produce statistical analysis plans and data displays; provide input to CRF design and data management processes; perform periodic review of clinical data).
CMR Surgical Ltd(Senior) Clinical Scientist CMR Surgical Ltd(Senior) Clinical ScientistCambridge, MAContribute to interpretation of trial results and draft clinical trial reports - Lead critical assessment of scientific literature including targeted and systematic reviews - Support the team in design and execution of pre-clinical studies - Support regulatory submissions and post-market surveillance activities Wed expect you to be willing to turn your hand to anything within the remit that helps the team deliver its objectives. We offer a competitive salary and a great benefits package including a bonus, non-contributory pension, private healthcare which covers pre-existing conditions, annual personal day for every employee to use however they wish and enhanced global parental leave pay.
TalentBurst, Inc.Clinical/Development - Senior Clinical Scientist TalentBurst, Inc.Clinical/Development - Senior Clinical ScientistCambridge, MAClinical Scientist will ideally be familiar with drug development and regulatory requirements and will deploy this expertise in the execution of a number of key responsibilities: Contributes to program team meetings, scientific advisory boards, study steering committees and data/safety monitoring meetings; may represent function in collaborative activities with other departments; Member of the Clinical Study Team and Global Clinical SubTeam. Authors and/or reviews documents related to trials, such as medical monitoring plans, SAPs, informed consents and clinical components of the Clinical Study Reports with minimal guidance and supports the development of regulatory documents; performs quality review and may approve; adjudicate and resolve cross functional comments with minimal support.
Merck & Co IncClinical Director (Principal Scientist), Clinical Research, Immunology - Rheumatology Merck & Co IncClinical Director (Principal Scientist), Clinical Research, Immunology - RheumatologyBoston, MA$255,800–$402,700 / yearThe Clinical Director is responsible for maintaining a strong scientific fund of knowledge by: Maintaining awareness of scientific developments within their area of expertise, in terms of new scientific findings, research methodologies. Job Description: The Clinical Director (Principal Scientist) has primary responsibility for planning and directing clinical research activities involving new or marketed medicines in the Immunology therapeutic area.
Kymera TherapeuticsNewSenior Manager, Clinical Scientist, Respiratory Kymera TherapeuticsSenior Manager, Clinical Scientist, RespiratoryWatertown, MA$145,000–$215,000 / yearHaving advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Collaborate within a matrix environment, collaborating with medical directors, regulatory affairs, translational medicine, clinical operations, data management, biostatistics, and other departments to drive clinical development programs forward.
Merck & Co IncClinical Director (Principal Scientist), Translational Medicine, Immunology Merck & Co IncClinical Director (Principal Scientist), Translational Medicine, ImmunologyBoston, MA$260,300–$409,700 / yearInterface broadly with key functions including Discovery Sciences, Preclinical Pharmacology, Pharmaceutical Sciences, Toxicology, Translational Biomarkers, Translational Medicine Operations, Translational Medicine-EU, Drug Metabolism/Modeling & Simulation, Regulatory Affairs, and late-stage Clinical Research throughout research sites around the world. • Contributing to the identification of novel targets by partnering with discovery research teams to bring a clinical perspective into the earliest stages of target identification and validation and executing clinical studies to evaluate the relevance of potential targets to human disease in order to justify investment in clinical development programs.
Eli Lilly and CoNewDirector - Clinical Research Scientist Eli Lilly and CoDirector - Clinical Research ScientistBoston, MA$193,500–$338,800 / yearOur current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Organization Overview: Verve, a wholly owned subsidiary of Eli Lilly, is seeking a Senior Director - Clinical Research Scientist (CRS) to help lead clinical trial efforts for our innovative gene editing therapies targeting cardiovascular disease.
Pfizer IncDirector, Clinical Development Scientist (Non-MD) Pfizer IncDirector, Clinical Development Scientist (Non-MD)Cambridge, MA$176,600–$294,300 / yearProvides clinical guidance to the development of the clinical data collection strategy, instruments, and data review plan, ensuring alignment with the protocol and SAP, optimized data collection principles, and clinical data review best practice; sets the clinical data review strategy and leads the team in the review of emerging clinical data and trends; reviews and queries data; presents data to internal and external stakeholders; partners with site-facing colleagues in support of data issue resolution; ensures all clinical queries are appropriately addressed in support of database lock. Provides clinical guidance to the development of the Safety Review Plan and Safety Narrative Plan; reviews safety data and ensures clinical documents are updated in response to emerging safety profile; tracks and reconciles Serious Adverse Events; leads clinical safety data discussion during Safety Review Team meetings in collaboration with Medically Qualified Individual(s); reviews safety narratives.
Foundation Medicine IncSr Scientist, Clinical Development Foundation Medicine IncSr Scientist, Clinical DevelopmentBoston, MA$143,000–$179,000 / yearThis role executes on strategic scientific collaborations involving a range of functions and external collaborators, driving studies that establish the clinical validity and utility of products and biomarkers aligned to Clinical Development Plans and FMI enterprise strategy. Senior Scientist, Clinical Development is a scientist with translational expertise leading key scientific studies from concept through to publication, focused on the value of FMI's products in clinical practice and oncology drug development.
TalentBurst, Inc.Clinical/Development - Scientist TalentBurst, Inc.Clinical/Development - ScientistCambridge, MAQualifications PhD in Chemistry, Biochemistry or related disciplines with 1-4 years industry experience, Master's degree with > 6 years related industry experience or Bachelor's degree with > 10 years related industry experience respectively, with demonstrated chromatographic separation, method development / qualification and structure elucidation expertise. Key Responsibilities Develop, qualify, and troubleshoot chromatographic (GC, HPLC/UPLC) and LCMS based methods for the identification, characterization, and impurity profiling of oligonucleotides, siRNAs, and their formulations, as well as raw material related analytical methods and other methods as needed.
Merck & Co IncDistinguished Scientist, Clinical Research, Thoracic Malignancies Merck & Co IncDistinguished Scientist, Clinical Research, Thoracic MalignanciesBoston, MA$310,900–$489,400 / yearWork closely with a cross-functional group of experts in commercialization, regulatory affairs, statistics, medical affairs, and manufacturing to manage clinical development projects; and assist the Section Head in ensuring that appropriate Corporate personnel is informed of the progress of studies of our company and competitors drugs and internal and external expert opinion on scientific questions relevant to their areas of responsibility. Must have experience in industry in the field of Thoracic Oncology Minimum of 3 years of clinical medicine experience Minimum of 5 years of industry experience in drug development Demonstrated record of scientific scholarship and achievement A proven track record in clinical medicine and background in biomedical research is essential Strong interpersonal skills, as well as the ability to function in a team environment, are essential.
LanceSoft IncClinical/Development - Scientist, Analytical Development LanceSoft IncClinical/Development - Scientist, Analytical DevelopmentCambridge, MAFull timeThe Scientist, is part of Analytical Development Starting Material Group and will be responsible for Develop, qualify and transfer GC, HPLC, UPLC and mass spectrometry based assays of starting materials, raw materials, intermediates and excipients to suppliers, CMOs and QC. Author and review method development and qualification reports and SOPs for test methods, as well as transfer / qualification protocols and reports related to critical starting materials / intermediates / excipients.
LanceSoft IncMedical Technologist (Clinical Laboratory Scientist MT/MLS/CLS) LanceSoft IncMedical Technologist (Clinical Laboratory Scientist MT/MLS/CLS)West Roxbury, MAOperate automated analyzers (Client Architect, Client Alinity, Advanced Instruments Osmos, Polymedco OC80). This policy applies to all employment practices within our organization, including hiring, recruiting, promotion, termination, layoff, recall, leave of absence, compensation, benefits, training, and apprenticeship.
Merck & Co IncNewSenior Data Scientist, Neuroscience Biomarker Discovery Merck & Co IncSenior Data Scientist, Neuroscience Biomarker DiscoveryCambridge, MA$144,800–$227,900 / yearRequired Skills: Alzheimer''s Disease, Biological Research, Biomarker Identification, Biomarkers, Collaborative Research, Computational Biology, Database Design, Data Engineering, Data Modeling, Data Science, Data Visualization, Detail-Oriented, Genome, Machine Learning (ML), Neurodegenerative Diseases, Neurological Disorders, Neuroscience, Omics, Parkinson''s Disease, Programming Languages, Proteomics, Self Motivation, Stakeholder Relationship Management. They will work alongside other data scientists, geneticists, AI/ML scientists in the department to develop and apply innovative approaches to analyze and integrate proteomics data with WGS, bulk/single-cell/spatial RNAseq, and metabolomics data to identify disease subtypes and predict therapeutic responses of biomarkers and clinical endpoints in specific subgroups of patients.
Johnson & JohnsonPrincipal Data Scientist - Oncology Johnson & JohnsonPrincipal Data Scientist - OncologyCambridge, MAAll Job Posting Locations: Cambridge, Massachusetts, United States of America, Raritan, New Jersey, United States of America, San Diego, California, United States of America, Spring House, Pennsylvania, United States of America, Titusville, New Jersey, United States of America. Work with Data Science & Digital Health colleagues, IT, and DevOps teams to deploy and manage the graph database infrastructure, focusing on high availability, scalability, and recovery operations specifically geared toward Oncology R&D needs and applications.
Iterative HealthNewStaff Data Scientist Iterative HealthStaff Data ScientistCambridge, MA$200,000–$325,000 / yearBy combining deep expertise in clinical trials with cutting-edge AI, we empower research teams and study sponsors to expand and expedite access to novel therapeutics for patients in need. New York pay range$200,000—$325,000 USDAt Iterative Health, we're actively working towards creating an environment that is representative of the diversity of patients our technology serves.
Merck & Co IncSenior Director (Senior Principal Scientist), Translational Medicine, Immunology Merck & Co IncSenior Director (Senior Principal Scientist), Translational Medicine, ImmunologyBoston, MA$286,900–$451,600 / yearInterface broadly with key functions including Discovery Sciences, Preclinical Pharmacology, Pharmaceutical Sciences, Toxicology, Translational Biomarkers, Translational Medicine Operations, Translational Medicine-EU, Drug Metabolism/Modeling & Simulation, Regulatory Affairs, and late-stage Clinical Research throughout sites in the USA, UK and Belgium. Translational Medicine is specifically responsible for: • Contributing to the identification of novel targets by partnering with discovery research teams to bring a clinical insight into the earliest stages of target identification and validation, and executing clinical studies to evaluate the relevance of potential targets to human disease in order to justify investment in full development.
Lahey Hospital and Medical CenterStaff Scientist I - Quantitative MRI & Generative AI for Cardiovascular Imaging Lahey Hospital and Medical CenterStaff Scientist I - Quantitative MRI & Generative AI for Cardiovascular ImagingBoston, MA$60,320–$150,009.60 / yearKey Responsibilities: • Research and develop deep learning models for MRI reconstruction, segmentation, quantification, and image enhancement • Design, optimize, and evaluate AI pipelines to improve image acquisition efficiency, image quality, and robustness • Integrate AI methods with quantitative CMR imaging biomarkers, including myocardial blood flow, strain, and tissue characterization • Develop and apply methods for multi-modality data integration, combining imaging, physiologic signals (e.g., ECG), genetic, and clinical data for diagnostic and prognostic modeling • Perform rigorous model validation, including reproducibility testing, bias assessment, and external validation • Design, develop, and implement user-friendly software platforms for clinical deployment of AI-enabled imaging tools. USD FLSA: Exempt Req ID: JR89997 330 Brookline Avenue, Boston, MA, 02215 Get directions Get Directions Beth Israel Deaconess Medical Center 330 Brookline Avenue, Boston, MA 02215 Start Mode Car Transit Bike Walk Transit Bus Subway Train Tram Rail Default Fewer transfers Less walking Avoid Tolls Highways Ferries G Google Maps Apple Maps Waze Apple Maps doesn't support Bike mode; we'll open Driving.
OneStudyTeamNewSenior Data Scientist OneStudyTeamSenior Data ScientistBoston, MARemote$140,000–$190,000 / yearDevelop Other Advanced Statistical Models: Create and refine predictive models (Bayesian inference, regression analysis, time-series forecasting) to address other key clinical trial challenges and improve decision-making. Patient Matching/Ranking Algorithms: Support projects to build algorithms that intelligently match patients to (or rank patients for) appropriate clinical trials, enhancing recruitment efficiency and patient inclusion.
Lahey Hospital and Medical CenterNewStaff Scientist II - PhD Biostatistician Lahey Hospital and Medical CenterStaff Scientist II - PhD BiostatisticianBoston, MA$83,200–$312,000 / yearFor non-bench research, non-clinical staff scientists, knowledge of epidemiology, outcomes research, evidence-based medicine, and experience using longitudinal datasets, data repositories and statistical Analysis with SAS, STATA or SPSS. Problem Solving: Ability to address problems that are broad, complex and abstract, often involving Medical Center-wide issues and requiring substantial creativity, resourcefulness, staff engagement, Lean diagnostic techniques, negotiation and diplomacy to develop solutions.
Dana-Farber Cancer Institute IncResearch Scientist (Harvard TH Chan School of Public Health) Dana-Farber Cancer Institute IncResearch Scientist (Harvard TH Chan School of Public Health)BOSTON, MA$145,000–$162,000 / yearMentoring Responsibilities: Regularly mentor and advise more junior statisticians in all aspects of their responsibilities and career development Functions as team leader on projects, advises and supervises more junior members of the team and participates in the annual evaluation of more junior members. Service to Dana-Farber and Dana-Farber/Harvard Cancer Center: Independently represents the department on HCC and DFCI committees, including but not limited to Scientific Review Committees (SRC) and Institutional Review Board (IRB).
Formation Bio IncSenior Data Scientist Formation Bio IncSenior Data ScientistBoston$170,000–$215,000 / yearResponsibilitiesLead and execute complex data science projects that directly advance our drug development portfolioDevelop and implement sophisticated models for therapeutic hypothesis evaluation including patient stratification and biomarker identificationDesign and create AI models for modernizing clinical trial evaluations including surrogate endpointsAid in the development and training of AI agents to automate and optimize biomedical workflowsCollaborate cross-functionally with clinical technical and research teamsPresent complex analytical findings to senior stakeholders including executive leadershipAbout YouRequired QualificationsPhD in computational sciences or life sciences3 years of post-academic experience in life sciences biotech pharma consultingStrong programming skills particularly in PythonExtensive experience in multi-modal bioinformatics analysisPreferred QualificationsProven expertise in cloud computing environments including proficiency with tabular andor graph databasesStrong background in machine learning and deep learning particularly in biological applicationsExperience with large language models LLMDemonstrated ability to collaborate effectively with engineering teams on production systemsStrong communication skills with proven ability to present complex technical findings to senior stakeholdersCompensationSalary ranges are informed in part by geographic location in addition to other factors. Formation Bio partners acquires or in-licenses drugs from pharma companies research organizations and biotechs to develop programs past clinical proof of concept and beyond ultimately helping to bring new medicines to patients.
Eurofins Scientific SENewScientist - Off-Target Genomics (Gene Therapy) Eurofins Scientific SEScientist - Off-Target Genomics (Gene Therapy)Boston, MA$104,000–$112,320 / yearEurofins Scientific is a global leader in life sciences, delivering a broad range of analytical testing services across industries including pharmaceuticals, food, environmental, and clinical research. We are seeking a Scientist - Off-Target Genomics (Gene Therapy) to lead and execute genomic safety assessment strategies for gene editing therapeutics.
Flagship Pioneering IncNewPioneering Medicines: Principal Scientist / Senior Principal Scientist, Bioanalytical Lead | Drug Metabolism & Pharmacokinetics Flagship Pioneering IncPioneering Medicines: Principal Scientist / Senior Principal Scientist, Bioanalytical Lead | Drug Metabolism & PharmacokineticsCambridge, MA$148,000–$203,500 / yearFlagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company's annual list of the World's Most Innovative Companies. Harnessing the drug development expertise of its team together with the power of Flagship''s multiple scientific platforms, Pioneering Medicines explores and identifies new product concepts which are then advanced jointly with Flagship's bioplatform companies.
Xenon7Post Doctoral Scientist- Human Genomics and Translational Data Science Xenon7Post Doctoral Scientist- Human Genomics and Translational Data ScienceBoston, MAWe are seeking a Statistical Geneticist with expertise in whole genome sequencing (WGS), proteomics, and clinical outcomes analysis to advance our research in identifying novel therapeutic targets. The Cardiometabolic Research (CMR) Therapeutic Area of our client, focuses on the discovery of biologic, small molecule and genetic therapeutics for the treatment of cardiometabolic diseases and associated complications.
Merck & Co IncNewClinical Director, Clinical Research, Ophthalmology Merck & Co IncClinical Director, Clinical Research, OphthalmologyBoston, MA$255,800–$402,700 / yearThe Clinical Director is responsible for maintaining a strong scientific fund of knowledge by: Maintaining awareness of scientific developments within his/her area of expertise, in terms of new scientific findings, research methodologies. The Clinical Director (Principal Scientist) has primary responsibility for planning and directing clinical research activities involving new or marketed medicines in the ophthalmology therapeutic area.
Novartis AGNewSenior Scientist I / II - Translational Immuno‑Oncology Research (OTR) Novartis AGSenior Scientist I / II - Translational Immuno‑Oncology Research (OTR)Cambridge, MA$93,800–$174,200 / yearKey Responsibilities, include, but are not limited to:Design, develop, troubleshoot, and optimize immunological assays-such as flow cytometry and single-cell profiling-and implement advanced technologies like single-cell RNA sequencing and multiplexed imaging to characterize immune cell populations and identify biomarkers from peripheral blood and tissues. Senior Scientist I: Bachelor's degree in cell and molecular biology or a related discipline with at least 5 years of relevant work experience; or Master's degree in cancer immunology or a related discipline with a minimum of 3 years of relevant work experience.
Novartis AGSenior Principal Scientist/Associate Director PK Sciences (DUAL LEVEL POSTING) Novartis AGSenior Principal Scientist/Associate Director PK Sciences (DUAL LEVEL POSTING)Cambridge, MA$138,600–$257,400 / yearThe scope of the role potentially includes small molecules, biologics/therapeutic proteins, antibody drug-conjugates, radioligand therapies and/or cell therapies across major therapeutic areas in Novartis, including oncology, immunology, cardiovascular renal metabolism, neuroscience, and global health. This position drives close interdisciplinary collaboration among the PK Science disciplines, Drug Disposition (ADME, BA), Modeling & Simulation (M&S), and Operations through PK science sub-teams to achieve a holistic and integrative perspective of the ADME/clinical pharmacology properties of candidates and drugs.
Bristol-Myers Squibb CoNewSenior Scientist, Discovery Biology Oncology Bristol-Myers Squibb CoSenior Scientist, Discovery Biology OncologyCambridge Crossing, MA$137,570–$166,706 / yearProficient with molecular and cellular biology related techniques, including but not limited to 2D/3D/spheroid cell culture and related cellular assays, Western blot and/or JESS, qRT-PCR, flow cytometry, proliferation and/or cytotoxicity assays (CyQuant, CTG, apoptosis, IncuCyte, etc.), ELISA, MSD and/or HTRF assays, colony formation assay, processing of DNA/RNA/protein, IP/Co-IP. In addition, the individual will coordinate with other functions, such as informatics and predictive science, lead discovery and optimization, in vivo pharmacology, and translational research teams to design/execute work related to patient stratification, identification of appropriate PD markers and assay development/transfer for miniaturization, among others to ensure timely project advancement.
AstraZeneca PlcScientist Bioscience in vivo, Respiratory and Immunology AstraZeneca PlcScientist Bioscience in vivo, Respiratory and ImmunologyWaltham, MA$92,252–$138,378 / yearIn this role, you will be an in vivo experimental scientist within Respiratory and Immunology Department focusing on developing therapeutics for the treatment of immune and autoimmune diseases such as SLE, fibrosis and arthritis using mouse models. Strong expertise in in vivo mouse models and hands-on in vivo skills is required and multiparameter flow cytometry, multiplex cytokine read-outs, qPCR is essential.
SanofiSenior Scientist - Process Modelling SanofiSenior Scientist - Process ModellingFramingham, MA$100.50–$145.17 / hourAs experimental data becomes readily available, the data consumption strategy is taking a central role in the department, with a strong focus on data preparation, data flow and data consumption, feeding applications developed in-house and commercial software used across CMC for data visualization, data modeling and advanced data analytics. The global CMC (Chemistry Manufacturing and Control) function is responsible for process development activities in R&D, designing appropriate control strategy to deliver processes of optimum product quality, supplying material for clinical trials and ensuring robust transfer of the process to our commercial organization.
Tempus AI IncData Scientist II, Outcomes Research Tempus AI IncData Scientist II, Outcomes ResearchBoston, MA$90,000–$135,000 / yearThe Outcomes Research team partners with external Pharma, biotech, and academic institutions to provide best-in-class data, analysis, and methodological guidance for Tempus's real-world data (RWD) offering. Responsibilities: Lead and execute HEOR and real-world evidence (RWE) projects (e.g., outcomes analysis, treatment patterns, healthcare resource utilization) with external Pharma, academic, and other partners.
Karwell TechnologiesAssociate Scientist Karwell TechnologiesAssociate ScientistCambridge, MAResponsibilities: Complete routine PD-grade viral vector production operations at both bench scale and pilot scale, including but not limited to media preparation, culture initiation, seed train maintenance and bioreactor operations, to support process development studies and material generation for pre-clinical programs. Associate Scientist is responsible for the development of robust, efficient, scalable and transferable lentiviral vector (LVV) manufacturing for early and late-stage cell therapy programs, for both ex-vivo and in-vivo delivery approaches.
Boston Children's HospitalGenomic Scientist Boston Children's HospitalGenomic ScientistBoston, MAKey ResponsibilitiesProducing innovative solutions driven by exploratory data analysis of complex and high-dimensional datasets; applying knowledge of statistics, machine learning, programming, data modeling, and advanced mathematics to generate and test hypotheses and interpret the results of experiments. Presenting at project and internal meetings; effectively conveying progress and asserting point of view; constructively discussing issues and providing facts; building credibility and trust by asking thoughtful questions and actively listening; running productive project meetings that advance problem-solving.
Formation Bio IncData Scientist - Portfolio Optimization Formation Bio IncData Scientist - Portfolio OptimizationBoston, MA$154,500–$202,000 / yearThe skills you develop here - portfolio construction over assets with radically asymmetric risk profiles, clinical trial analytics, AI/ML in production, and risk management across multi-year horizons - can directly impact the delivery of new and effective therapeutics to patients by best aligning impactful medicines with economic incentives. Recognizing that this development bottleneck may ultimately limit the number of new medicines that can reach patients, Formation Bio, founded in 2016 as TrialSpark Inc., has built technology platforms, processes, and capabilities to accelerate all aspects of drug development and clinical trials.
Lahey Hospital and Medical CenterStaff Scientist I/Flow Cytometry Lahey Hospital and Medical CenterStaff Scientist I/Flow CytometryBoston, MA$100,006–$140,005 / yearFor non-bench research, non-clinical staff scientists, knowledge of epidemiology, outcomes research, evidence-based medicine, and experience using longitudinal datasets, data repositories and statistical Analysis with SAS, STATA or SPSS. Problem Solving: Ability to address problems that are broad, complex and abstract, often involving Medical Center-wide issues and requiring substantial creativity, resourcefulness, staff engagement, Lean diagnostic techniques, negotiation and diplomacy to develop solutions.
WuXi Biologics Cayman IncPrincipal Scientist - Translational Biology & Program Leadership WuXi Biologics Cayman IncPrincipal Scientist - Translational Biology & Program LeadershipNatick, MA$95,000–$155,000 / yearJob Summary: We are seeking a strategic and scientifically driven Principal Scientist with strong expertise in translational immunology, ex vivo biology, and therapeutic program leadership to lead cross-functional drug discovery initiatives across oncology, autoimmune, and inflammatory disease programs. In addition to technical expertise in ex vivo immune assays and complex 3D model systems, the ideal candidate will possess demonstrated experience leading multidisciplinary discovery teams, coordinating program activities across functions, and influencing strategic direction in a fast-paced biotechnology environment.
GSK plcNewScientist, In Vivo Immunology GSK plcScientist, In Vivo ImmunologyCambridge, MA$89,925–$149,875 / yearPreferred Qualifications: If you have the following characteristics, it would be a plus: PhD with experience in viral immunology or infectious disease Experience with in vivo viral challenge models Experience working with multiple species Strong experience with immune-response related readout methods such as ELISA, Flow, Luminex, or qPCR methodologies. You will help design and write in vivo study protocols, coordinate and initiate preclinical studies, conduct experiments and analyze experimental data pertaining to the understanding of cellular mediated immune responses and humoral immune responses from novel vaccine candidates, formulations, and platforms.
AstraZeneca PlcAssociate Director - AI Scientist - Computational Radiology AstraZeneca PlcAssociate Director - AI Scientist - Computational RadiologyBoston, MA$144,648.80–$216,973.20 / yearOur R&T team plays a crucial role in supporting AstraZeneca's early oncology and late development strategy for an innovative pipeline that includes Antibody-Drug Conjugates (ADCs), Radio-conjugates, T-cell engagers, CAR-T therapies, bispecific antibodies, and small molecules. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles).
Monte Rosa Therapeutics, IncScientist, ADME & BioAnalytical Monte Rosa Therapeutics, IncScientist, ADME & BioAnalyticalBoston, MassachusettsOverview: Monte Rosa Therapeutics (MRT) seeks to recruit an experienced, creative and highly talented DMPK and ADME Scientist who is eager will assit in leading the discovery and development effort to grow the drug pipelines, as well as help lead external GxP compliance research efforts. Responsibilities: Work closely with the medicinal chemistry team, the Scientist Position will lead the Nonclinical Development efforts in troubleshooting and guidance to the discovery project team with a particular focus on optimizing properties for oral administration.
Advanced Regenerative Manufacturing Institute IncScientist Advanced Regenerative Manufacturing Institute IncScientistManchester, NHThe Advanced Regenerative Manufacturing Institute (ARMl)IBioFabUSA is a Member-based non-profit, member-driven, public-private partnership with a mission to advance the bioeconomy and transform the future of human health. The ideal candidate will have experience with process development or early phase GMP manufacturing, aseptic techniques and operations within a controlled manufacturing environment, SOP/Batch Record drafting, and other aspects of contract manufacturing.