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Clinical Scientist Jobs in Massachusetts

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Scientist II, Crispr-X - Gene Insertion CRISPR Therapeutics AG

South Boston, MA

$130,000–$140,000 / year

The Company has evolved from a pioneering research-stage organization into an industry leader, marking a historic milestone with the approval of CASGEVY (exagamglogene autotemcel [exa-cel]), the world's first CRISPR-based therapy, approved for eligible patients with sickle cell disease and transfusion-dependent beta thalassemia. Hands-on experience with chimeric antigen receptor (CAR) T cell engineering, including CAR construct design, gene editing and/or transgene delivery in primary human T cells, and functional characterization of the resulting CAR-T cells.

30+ days ago

Scientist II, CRISPR-X - Gene Insertion CRISPR Therapeutics AG

South Boston, MA

$130,000–$140,000 / year

30+ days ago

Principal Scientist – Analytical Development, Biologics Hemab ApS

Cambridge, MA

Lead and manage analytical CROs/CDMOs, material suppliers, consultants, vendors and collaborators; monitor regulatory trends, integrate new analytical approaches, identify opportunities to improve efficiency and reduce costs, and advise colleagues on data interpretation. Youll set analytical strategy, guide GMP and QC work with our external partners, and utilize your expert judgement to work through method, validation and CMO challenges without waiting for someone else to define the answer.

19 days ago

Research Scientist Biomedical Engineering Boston University

Boston, MA

The role spans analog and digital circuit design, PCB layout, FPGA and embedded firmware, sensor and camera systems, and integration of optical and electronic subsystems into compact wearable packages. Preferred: Background in wearable/implantable biomedical devices, near-infrared optical spectroscopy (CW-NIRS, SCOS, DCS), or low-power wireless (BLE/Zigbee); publication record in instrumentation.

30+ days ago

Research Leader / Senior Scientist (Medicinal Drug Design), Cambridge, MA Isomorphic Labs

Cambridge, MA

Proven track record of project leadership / leading medicinal chemistry efforts on drug discovery projects, demonstrating significant contributions to project progression (ideally from hit identification through to lead optimisation or candidate nomination), with familiarity of optimisation of ADME properties. Rapidly drive drug discovery programs to value inflection points by deploying your knowledge of modern discovery principles and synthetic organic chemistry, taking ownership as either an overall Project Lead or Medicinal Chemistry Lead.

30+ days ago

Research Leader / Senior Scientist (In vitro / Cellular Pharmacology), Cambridge, MA Isomorphic Labs

Cambridge, MA

These are exciting opportunities to work closely with world-leading ML and drug discovery experts to develop imaginative new ways to test biological hypotheses, building a deep mechanistic understanding of drug target interactions to drive our projects forward. These roles are ideal for experienced in vitro pharmacologists with significant working knowledge of biophysical, biochemical and/or cell-based functional assays, and extensive experience of providing quantitative in vitro pharmacology expertise within drug discovery projects.

30+ days ago

Senior Scientist, Computational Biology Tessera Therapeutics Inc

Somerville, MA

$141,000–$171,000 / year

His group supports drug candidate programs through genotoxicity risk assessment, develops computational approaches to study gene writing biology, and builds scalable data and analysis infrastructure to support molecular assay design and knowledge mining. Broad knowledge of genome editing technologies and associated off-target discovery assays (i.e. WGS; targeted sequencing; GUIDE-seq, Digenome-seq discovery / verification; large and small structural variations and translation effects; NGS QC).

30+ days ago

Research Scientist, Pharmacy, Physio & Biophys Boston University

Boston, MA

$0.01–$0.20
Full time

Primary human neuronal culture from induced pluripotent stem cells, transgenic rodent models, and human clinical samples (blood and postmortem brain tissue) will be utilized for biochemical analysis using advance analytic instruments. Please email CV to Weiming Xia, PhD, Professor, Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine (wxia@bu.edu).

27 days ago

Senior/Principal Scientist, MPN Biology, Translational Sciences PharmaEssentia Corp

BEDFORD, MA

Summary of Key Responsibilities: Study Design and Execution: Lead the design, planning, and execution of POC and translational studies in healthy and MPN mouse models and primary human cellular and tissue systems to generate comprehensive pharmacology and biomarker data packages including MOA and differentiation from competitor programs. Founded in 2003 by a team of Taiwanese American executives and renowned scientists from U.S. biotechnology and pharmaceutical companies, today we are listed on the Taipei Exchange (TPEx: 6446) and are expanding our global presence with operations in the U.S., Japan, China and Korea, along with a world-class biologics production facility in Taichung.

30+ days ago

Associate Director, Clinical AI Translation & Solutions AstraZeneca Plc

Cambridge, MA

$144,648.80–$216,973.20 / year

Essential Skills/Experience: PhD in Computer Science, Machine Learning, Statistics, Biomedical Informatics, Computational Biology, or a related quantitative discipline; or an MD, master's degree, or equivalent experience supported by a strong computational track record. Workflow Discovery and Design: Observe CRAs, site-monitoring leaders, clinical operations, and medical stakeholders to convert pain points into product requirements, data contracts, acceptance criteria, and evaluation plans.

16 days ago

Cell-Based Testing Scientist Eurofins USA PSS Insourcing Solutions

Lexington, Massachusetts

$29–$34
Full time

Independently performs routine testing such as but not limited to Binding ELISA, Cell based Potency, Enzyme Activity - using established test methods, including associated protocol/report documentation and presentations. Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable.

13 days ago

Senior Scientist II - Drug Metabolism Novo Nordisk

Lexington, MA

Working cross functionally with medicinal chemistry, pharmacology and other discovery teams, you will lead DMPK efforts to optimize candidates using in vitro, in vivo and in silico methods where pharmacokinetic/pharmacodynamic (PK/PD) modeling and/or physiologically based pharmacokinetic (PBPK) hands-on capabilities are required. Internal relationships include working closely with technical staff & other members of the scientific leadership team; regular collaborations with members of other research departments at NN; & frequent interaction with project managers & other colleagues across global R&D.

12 days ago

Purification Associate Scientist - HPLC Eurofins USA PSS Insourcing Solutions

Boston, Massachusetts

$31–$41
Full time

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

9 days ago

Scientist II, mRNA Technologies Repertoire Immune Medicines

Waltham, MA

$120,000–$160,000 / year

The DECODE platform has been validated through four strategic partnerships with leading pharmaceutical companies—Bristol Myers Squibb, Genentech, Eli Lilly, and Pfizer—representing over $4.5 billion in disclosed total deal value and $185 million in upfront payments received to date. As part of the Integrated Therapeutics and Development team (ITED), you will partner closely with lipid nanoparticle technology, in vivo pharmacology, antigen discovery and validation, and computational sciences to advance drug candidates from concept through preclinical and toward clinical development.

4 days ago

Lead Scientist, Neuroendocrinology Zealand Pharma A/S

Cambridge, MA

Combining more than 25 years of peptide R&D expertise with a proprietary data platform that leverages advanced data-driven and AI/ML approaches, Zealand Pharma aims to lead a new era in obesity and metabolic health. The group focuses on neuroendocrine mechanisms of metabolic regulation, with particular emphasis on central targets for obesity, and studies the mechanism of action of drugs in the Zealand Pharma pipeline.

5 days ago

DMPK Scientist Schrodinger Inc

Cambridge, MA

$170,000–$290,000 / year

What you should have: PhD in life sciences, chemical engineering, pharmacokinetics, pharmaceutical sciences, or a related discipline with at least five years of experience working with DMPK in the pharmaceutical industry or Master's degree in life sciences, chemical engineering, pharmacokinetics, pharmaceutical sciences, or a related discipline with at least ten years of experience working with DMPK in the pharmaceutical industry. Schrödinger is honored to have been included in Crain''s New York Best Places to Work, BuiltIn''s NYC Best Place to Work, and Newsweek''s list of America''s 100 Most Loved Workplaces.

18 days ago

Deep Learning Scientist II, Protein Sciences Repertoire Immune Medicines

Watertown, MA

$150,000–$170,000 / year

Repertoire Immune Medicines is seeking a Deep Learning Scientist II to join the Artificial Immune Intelligence Team to accelerate the discovery and development of transformative therapeutics, exploiting proprietary datasets about T cell receptors interacting with peptide-MHC complexes. The DECODE platform has been validated through four strategic partnerships with leading pharmaceutical companies—Bristol Myers Squibb, Genentech, Eli Lilly, and Pfizer—representing over $4.5 billion in disclosed total deal value and $185 million in upfront payments received to date.

30+ days ago

Scientist II, Computational Biology (Single Cell & Spatial) eGenesis

Cambridge, MA

Develop scalable pipelines for high-dimensional single cell and spatial datasets, and build new analytical approaches where existing tools fall short (e.g., cross-species cell mapping, sparse or incomplete reference annotations). Track record of independently defining and answering open research questions, where the question, approach, or method was not set in advance, as shown by first-author publications, novel methods, or equivalent industry work.

30 days ago

mRNA Process Development Scientist Eurofins USA PSS Insourcing Solutions

Boston, Massachusetts

$32–$41
Full time

B.S. degree in chemistry, chemical engineering, or biochemistry (or related field) with 1+ years of relevant laboratory experience, or M.S. degree in chemistry, chemical engineering, or biochemistry (or related field) with at least 6 months of relevant laboratory experience. Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable.

17 days ago

Senior Scientist, Drug Substance MBX Biosciences

Burlington, MA

The Company's pipeline includes canvuparatide (MBX 2109) for the treatment of chronic hypoparathyroidism preparing for Phase 3 development; and an obesity portfolio that includes MBX 4291 in Phase 1 development and MBX 5765 in preclinical development, as well as additional discovery candidates. Company Overview: MBX Biosciences is a biopharmaceutical company focused on the discovery, development and commercialization of novel precision peptide therapies based on its proprietary PEP platform, for the treatment of endocrine and metabolic disorders.

29 days ago

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Clinical Scientist Jobs in Massachusetts

Scientist II, Crispr-X - Gene Insertion CRISPR Therapeutics AG

Scientist II, CRISPR-X - Gene Insertion CRISPR Therapeutics AG

Principal Scientist – Analytical Development, Biologics Hemab ApS

Research Scientist Biomedical Engineering Boston University

Research Leader / Senior Scientist (Medicinal Drug Design), Cambridge, MA Isomorphic Labs

Research Leader / Senior Scientist (In vitro / Cellular Pharmacology), Cambridge, MA Isomorphic Labs

Senior Scientist, Computational Biology Tessera Therapeutics Inc

Research Scientist, Pharmacy, Physio & Biophys Boston University

Senior/Principal Scientist, MPN Biology, Translational Sciences PharmaEssentia Corp

Associate Director, Clinical AI Translation & Solutions AstraZeneca Plc

Cell-Based Testing Scientist Eurofins USA PSS Insourcing Solutions

Senior Scientist II - Drug Metabolism Novo Nordisk

Purification Associate Scientist - HPLC Eurofins USA PSS Insourcing Solutions

Scientist II, mRNA Technologies Repertoire Immune Medicines

Lead Scientist, Neuroendocrinology Zealand Pharma A/S

DMPK Scientist Schrodinger Inc

Deep Learning Scientist II, Protein Sciences Repertoire Immune Medicines

Scientist II, Computational Biology (Single Cell & Spatial) eGenesis

mRNA Process Development Scientist Eurofins USA PSS Insourcing Solutions

Senior Scientist, Drug Substance MBX Biosciences

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