Serving as the Government's trusted technical advisor, the Technical Lead will collaborate closely with NCI leadership, principal investigators, biomedical researchers, clinicians, informaticians, and multidisciplinary engineering teams to develop innovative AI-enabled solutions supporting clinical research, scientific data management, and enterprise research platforms. The successful candidate will combine deep expertise in artificial intelligence, machine learning, biomedical informatics, cloud computing, and modern software engineering with exceptional customer engagement and communication skills to guide technology strategy, influence architectural decisions, and ensure delivery of scalable, secure, and scientifically rigorous AI capabilities aligned with NIH and NCI strategic priorities.