Principal Engineer, AI Security Lila SciencesPrincipal Engineer, AI SecurityCambridge, MassachusettsMulti-Layer AI Security (Network, Endpoint, Data) — Integrate AI security into existing enterprise security layers: network visibility and control over AI service access, API traffic inspection, and zero trust enforcement; endpoint security for developer machines, research environments, browsers, and plugins; data layer controls ensuring proper handling of sensitive data when interacting with AI systems. While Lila builds AI-powered systems, this role is primarily focused on securing the use of third-party and internally deployed AI tools across the enterprise — ensuring sensitive data, intellectual property, and scientific workflows are protected as AI becomes deeply embedded in how work gets done.
Senior Platform Security Engineer ASUSTeK ComputerSenior Platform Security EngineerBoston, MA$164,000–$237,000 / yearThe ideal candidate is a strong individual contributor who is eager to deepen their expertise in security architecture while working alongside experienced engineers across our Boston and Taipei offices. We are looking for an engineer with hands-on experience in application and cloud security, a proactive mindset for identifying and mitigating risk, and the ability to collaborate effectively across a multidisciplinary engineering team.
Cyber Security Analyst (1LoD) Kforce Inc.Cyber Security Analyst (1LoD)Woburn, MA$60–$73This position will focus on analyzing security telemetry across endpoint, network, email, and cloud environments to identify suspicious activity, uncover emerging threats, and strengthen the organization's overall security posture. Summary: Responsibilities include conducting threat hunting activities, investigating security alerts, analyzing indicators of compromise (IOCs), developing detection content, and supporting incident response efforts.
NETSCOUT SYSTEMS: IT Security Contractor Elevated ResourcesNETSCOUT SYSTEMS: IT Security ContractorWestford, MassachusettsThis position demands an organized, action oriented team player with the ability to prioritize daily work and support on multiple initiatives simultaneously; strong communication and customer focus is required. This position supports Information Security Office programs which include risk management, compliance management, audits and assessments, customer inquiries, and security awareness.
Manager, Security Governance & Risk EmburseManager, Security Governance & RiskBoston, MADemonstrable experience interacting with auditors and strategic partners in cloud-based environments similar to Emburse, relating to assurance frameworks such as SOX, PCI DSS, ISO 27001, SOC 2 Trust Principles, Business Continuity and Disaster Recovery, and Third-Party Risk Management. Provide management oversight and quality assurance for security and compliance audits while delegating day-to-day audit planning, evidence coordination, auditor interaction, and execution; intervene directly on material findings, scope disputes, control deficiencies, or issues requiring management judgment.
Director, Information Technology ReplimuneDirector, Information TechnologyWoburn, Massachusetts$202,000–$261,500 / yearThe RPx platform is designed to have a unique dual local and systemic activity consisting of direct selective virus-mediated killing of the tumor resulting in the release of tumor derived antigens and altering of the tumor microenvironment to ignite a strong and durable systemic response. The ideal candidate combines strong leadership, strategic thinking, and operational execution, with experience building high-performing teams, managing vendor relationships, and delivering technology solutions in regulated environments.
NewInformation System Security Engineer (ISSE) Cyber Defense TechnologiesInformation System Security Engineer (ISSE)Westford, MassachusettsResponsibilities: Systems Administration: Administer, maintain, upgrade, and ensure the readiness of several classified virtual enterprise systems and corresponding technologies (VMware, Cisco, Palo Alto, Windows Domain, Linux). Documentation & Procedures: Collaborate with the ISSO team and program/project staff to create, implement, and maintain procedural documents and operations (configuration management, continuous monitoring, business continuity, disaster recovery, etc.).
Director, Information Security WhoopDirector, Information SecurityBoston, MA$190,000–$220,000 / yearOwn security operations including detection, response, escalation, incident follow-up, and operational readiness, serving as Incident Commander during security events and acting as on-call executive escalation outside of business hours as needed, coordinating internal teams, external partners, and managed security service providers. Own the security posture for enterprise and internal use of AI technologies, including guardrails for access, data handling, monitoring, auditability, and the secure adoption of AI-enabled workflows in partnership with Architecture, Product Security, IT, and Legal.
Vice President of Information Security CareerscapeVice President of Information SecurityManchester, NH$175,000–$225,000 / yearFull timeDay to day, this role blends strategic planning with hands-on leadership of a growing security team, balancing incident response, risk governance, audits, and vendor management against long-term architecture and policy work. The ideal candidate thrives in a fast-paced, on-site environment, is comfortable being the executive voice on security matters, and has a track record of building trust with both technical teams and non-technical executives.
NewChief Information Security Officer DLA Piper LLP (US)Chief Information Security OfficerBoston, MA$550,000–$650,000 / yearExecutive-level knowledge of cybersecurity strategy, governance, risk, compliance, privacy, data protection, incident response, threat intelligence, vulnerability management, identity and access management, cloud and network security, application security, endpoint protection, email security, encryption, logging and monitoring, disaster recovery, business continuity, third-party risk, DevSecOps, modernized secure development practices including AI SDLC, and secure technology adoption. Operating as a trusted advisor to firm leadership, the Office of General Counsel, Information Technology, Information Governance, Risk Management, practice leadership, and global counterparts, the CISO ensures the confidentiality, integrity, and availability of client and firm information while enabling innovation, responsible AI adoption, operational resilience, and exceptional client service.
ISSO III - Information Systems Security Officer III Watermark Risk Management InternationalISSO III - Information Systems Security Officer IIIBedford, MAFull timeThe primary function is working within Special Access Programs (SAPs) supporting Department of Defense (DoD) agencies, such as HQ Air Force, Office of the Secretary of Defense (OSD) and Military Compartments efforts. Multiple considerations are taken into account when determining the final salary/hourly rate, including but not limited to, Contract Wage Determination, education and certifications, relevant work experience, related skills and competencies, as well as Federal Government Contract Labor Categories.
Information System Security Officer The Charles Stark Draper LaboratoryInformation System Security OfficerCambridge, MassachusettsDraper supports many programs to improve work-life balance including workplace flexibility, employee clubs ranging from photography to yoga, health and finance workshops, off site social events and discounts to local museums and cultural activities. • 1-3 years year relevant industry experience is required, • Preferred experience with RMF (NIST SP 800-53, JSIG, DAAG, ICD 503), IR, Vulnerability Management, SCAP, STIG, and Security-Relevant Tools.
NewInformation Security Lead Click Therapeutics Inc.Information Security LeadBoston, MA$130,000–$200,000 / yearConsistently named a best place to work, Click fosters an inclusive, diverse workforce of innovators, clinicians, scientists, researchers, designers, technologists, engineers and more, united in a common mission to provide patients everywhere access to safe and effective prescription digital therapeutics. Click Therapeutics may at its business discretion decide to or refrain from obtaining, maintaining and/or extending the temporary visa status and/or sponsoring a colleague for permanent residency and /or employment eligibility, considering factors such as availability of qualified U.S. workers and the colleague's long-term prospects for securing lawful permanent residence, among other reasons.
Senior Information System Security Officer (ISSO) - Marlborough, MA RTX CorpSenior Information System Security Officer (ISSO) - Marlborough, MAMarlborough, MAExperience providing technical security consultation for complex, cross-domain, heterogeneous classified networked environments in collaboration with internal/external Customers, Information Technology (IT). Experience working with and/or supporting computer technologies (such as: databases, operating systems, computer network hardware, software programs, hardware troubleshooting or electronics).
Information Systems Security Officer (Isso) CONTACT GOVERNMENT SERVICESInformation Systems Security Officer (Isso)Boston, MA$92,213.33–$125,146.66 / yearMaintain vulnerability scanning tool compliance, such as HBSS or ACAS, and patch management, such as IAVM to ensure IT staff pushes patches to all systems in an effort to maintain compliance with all applicable directives, manage system changes, and assess the security impact of those changes. The scope of this position includes full life-cycle Assessment and Authorization (A&A) management through all 6 Steps of the RMF process in support of the Government ISSM.In this role, you'll conduct security assessment, and information system security oversight activities in accordance with NIST 800.53 that support systems from the perspective RMF requirements.
NewSenior Information System Security Officer (ISSO) - Marlborough, MA (Sponsor Clearance) RTX CorpSenior Information System Security Officer (ISSO) - Marlborough, MA (Sponsor Clearance)Marlborough, MAExperience providing technical security consultation for complex, cross-domain, heterogeneous classified networked environments in collaboration with internal/external Customers, Information Technology (IT). Experience working with and/or supporting computer technologies (such as: databases, operating systems, computer network hardware, software programs, hardware troubleshooting or electronics).
Senior Information Security Engineer First Technology Federal Credit UnionSenior Information Security EngineerMarlborough, MAFull timeMonitor and assess information security metrics, key risk indicators (KRIs), control effectiveness measures, and trends to identify emerging risks and opportunities for improvement. Support governance and oversight of security domains including identity and access management, vulnerability management, cloud security, application security, data protection, and cybersecurity operations.
Information Systems Security Engineer (ISSE) Abacus TechnologyInformation Systems Security Engineer (ISSE)Hanscom AFB, Massachusetts$180,715–$200,000 / yearThere are multiple factors that can impact a final salary, including, but not limited to, Contract Wage Determination, relevant work experience, skills and competencies that align to the specified role, geographic location (if remote or different from the stated location for this position), education and certifications as well as Federal Government Contract Labor categories. Overview: Abacus Technology is seeking an Information System Security Engineer (ISSE) to ensure system and application deliverables meet all required cyber security policies and regulations for the Technical Advisory and Assistance Services (TAAS) program at Hanscom AFB.
Information Systems Security Engineer in Hanscom, MA Georgia Tek SystemsInformation Systems Security Engineer in Hanscom, MAHanscom, MAThe Contractor shall demonstrate experience in: security systems engineering involving hardware and software operating systems and application solutions. US Government contract proposals as IA/security engineering subject matter expert, and implementation of DoD and Federal IA A&A processes.
Information Systems Security Manager (ISSM) I TAC Integrated SolutionsInformation Systems Security Manager (ISSM) IMassachusettsinclude accountability, access rights, and special handling requirements Ensure the development and implementation of an information security education, training, and awareness program, to include attending, monitoring, and presenting local cybersecurity training. Primary support will be working within Special Access Programs (SAPs) supporting Department of Defense (DoD) agencies, such as HQ Air Force, Office of the Secretary of Defense, and Military Compartmentalized efforts.