Senior Principal AI Engineer, Agentic AI Platform & Control Tower Ops Vertex Pharmaceuticals IncSenior Principal AI Engineer, Agentic AI Platform & Control Tower OpsBoston, MA$188,000–$282,000 / yearIn addition to building out the core platform, this leader will own the vision for a centralized AI Control Tower / Control Plane / Gateway that enables agent monitoring, observability, policy enforcement, governance, and operational controls across AI solutions at Vertex. Demonstrated experience using AI-assisted software development and autonomous coding agents to design, generate, test, review, debug, optimize, and refactor code across complex enterprise systems.
Principal AI Engineer MatillionPrincipal AI EngineerManchester, NHAs a Principal Engineer on our Maia AI team, you'll be at the heart of everything we do: designing agentic AI systems, leveraging evals to continually validate their performance as model capabilities evolve, building new tools and integrations, and staying finger-on-the-pulse with the latest developments in Gen AI. Technical leadership experience - you've been a tech lead, influenced architecture decisions, and helped other engineers grow; you can communicate complex concepts to non-technical stakeholders without breaking a sweat.
Principal Engineer, Agentic AI Platform Integrations Vertex Pharmaceuticals IncPrincipal Engineer, Agentic AI Platform IntegrationsBoston, MA$166,640–$250,000 / yearVertex is seeking an Integrations Engineer, Agentic AI Platform to connect the AI/agentic platform to the systems, tools, and data sources that make AI valuable in real enterprise workflows. Enable AI workflows to interact reliably with core enterprise platforms such as collaboration tools, knowledge systems, workflow tools, and line-of-business applications.
Analytical Science And Technology Principal Scientist Vertex Pharmaceuticals, IncAnalytical Science And Technology Principal ScientistBoston, MA$138,400–$207,600 / yearThe successful candidate will provide scientific leadership across microbiology method lifecycle management, external laboratory oversight, investigations, compliance, and continuous improvement to ensure robust, inspection-ready testing throughout the global network. This role serves as the microbiology technical leader and subject matter expert responsible for microbiological methods and microbial control strategies supporting late-stage development and commercial products.
Principal Engineer, Vaida User Experience Vertex Pharmaceuticals, IncPrincipal Engineer, Vaida User ExperienceBoston, MA$166,640–$250,000 / yearWe seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. The ideal candidate blends strong frontend engineering expertise with exceptional UX and product instincts, translating complex backend capabilities into user experiences that are clear, intuitive, and scalable for 10,000+ employees.
NewPrincipal, Mergers and Acquisitions (M&A) Tax Baker Tilly Advisory Group, LPPrincipal, Mergers and Acquisitions (M&A) TaxTewksbury, MassachusettsBaker Tilly Advisory Group, LP and Baker Tilly US, LLP, trading as Baker Tilly, are independent members of Baker Tilly International, a worldwide network of independent accounting and business advisory firms in 141 territories, with 43,000 professionals and a combined worldwide revenue of $5.2 billion. The ideal candidate possesses deep technical expertise in complex corporate and flow-through transaction tax structuring and a proven track record of leading complex, high-stakes transactions with strategic tax insights that create significant value for Private Equity clients.
Oliver Wyman - Associate/ Engagement Manager / Principal - Tech Innovation Practice (Technical Architecture & Delivery Focus) Marsh & McLennan Companies IncOliver Wyman - Associate/ Engagement Manager / Principal - Tech Innovation Practice (Technical Architecture & Delivery Focus)Boston, MA$190,000–$195,000 / yearWe aim to attract and retain the best people and embrace diversity of age background, disability, ethnic origin, family duties, gender orientation or expression, marital status, nationality, parental status, personal or social status, political affiliation, race, religion and beliefs, sex/gender, sexual orientation or expression, skin color, veteran status (including protected veterans), or any other characteristic protected by applicable law. With offices in more than 70 cities across 30 countries, Oliver Wyman combines deep industry knowledge with specialized expertise in strategy, operations, risk management, and organization transformation.
Research Assistant, Addiction Psychiatry Boston Medical CenterResearch Assistant, Addiction PsychiatryBoston, MA$16.35–$22.84 / hourConducts patient recruitment, administers questionnaires, abstracts medical records, maintains patient databases, performs administrative tasks, assists in grant preparation, performs literature searches and participates with the research team in preparation of data and other reports. POSITION SUMMARY: The Research Assistant (RA) will support a new NIH-funded study, Ready 2 Respond: a randomized controlled trial (RCT) to evaluate the efficacy of a brief universal overdose prevention intervention in pediatric primary care.
Senior/Principal Mechanical Design Engineer Kaleidoscope Animations (Inactive)Senior/Principal Mechanical Design EngineerBoston, MAThe ideal candidate has deep experience designing highly complex electromechanical products and a strong understanding of high-volume manufacturing processes, including injection molding, thick-wall molding, die casting, and other metal molding/forming processes. We are seeking a highly experienced Sr/Principal Mechanical Design Engineer to lead the mechanical design and scale-up of complex robotic modules from initial development through high-volume production.
Principal Scientist, Translational Clinical Biomarkers - Hematology/Oncology Merck & Co IncPrincipal Scientist, Translational Clinical Biomarkers - Hematology/OncologyBoston, MA$190,800–$300,300 / yearRequired Skills: Biomarkers, Clinical Development, Clinical Research, Ethical Compliance, Immuno-Oncology, Mechanism of Action, Oncology, Patient Care, Pharmacodynamics, Protocol Development, Research Designs, Scientific Presentations, Scientific Writing, Strategic Thinking, Translational Medicine. For solid tumors, develop strategies addressing target expression, tumor biology, molecular subtype, immune contexture, circulating biomarkers, mechanisms of response and resistance, and potential predictive biomarkers.
Principal Software Engineer Boston Human Capital PartnersPrincipal Software EngineerBoston, MassachusettsRemoteThis role centers on building high-performance distributed systems, powering data-intensive services, and enabling seamless, secure integrations across modern IT and security ecosystems. only) and best suited for engineers who excel in fast-moving startup environments where autonomy, rapid iteration, and strong technical judgment are essential.
Principal Engineer, Ai/Ml Security DigitalOceanPrincipal Engineer, Ai/Ml SecurityBoston, MARemote$230,400–$288,000 / yearDeep, practitioner-level knowledge of adversarial ML attack and defence: evasion, poisoning, model extraction, membership inference, and prompt injection at both conceptual and implementation depth. Experience engaging executive and senior leadership audiences on technical risk: you can translate complex AI threat scenarios into business-level impact and justify investment decisions accordingly.
NewPrincipal, AI Operations & Infrastructure Automation IDC Research Inc.Principal, AI Operations & Infrastructure AutomationBoston, Massachusetts$139,000–$240,000 / yearFull timeIDC is currently able to employ remote workers in the following states: Arizona (AZ), California (CA), Colorado (CO), Connecticut (CT), Washington D.C. (DC), Florida (FL), Georgia (GA), Illinois (IL), Indiana (IN), Kansas (KS), Massachusetts (MA), Maryland (MD), Maine (ME), Michigan (MI), Minnesota (MN), Missouri (MO), Mississippi (MS), North Carolina (NC), New Hampshire (NH), New Jersey (NJ), New York (NY), Ohio (OH), Oregon (OR), Pennsylvania (PA), Rhode Island (RI), South Carolina (SC), Tennessee (TN), Texas (TX), Utah (UT), Virginia (VA), Vermont (VT), Washington (WA), and Wisconsin (WI). Additional responsibilities include: Own the end-to-end redesign of the infrastructure operating model, moving core workflows (provisioning, monitoring, incident response, patching, capacity management) from manual execution to automated, self-healing pipelines.
Principal, Market & Reference Data Partner's CapitalPrincipal, Market & Reference DataBoston, MassachusettsThis is a hands-on leadership role at the center of the firm’s investment, operations, risk, and technology workflows which involves owning the integrity of reference data that powers trading, portfolio management, performance, valuation, and reporting firmwide. The role combines deep subject matter expertise in financial instrument and market reference data with strong commercial discipline and the relationship-building skills needed to operate as a trusted partner to functional leaders across the firm.
TEMP Principal DevOps Engineer Doble Engineering CompanyTEMP Principal DevOps EngineerMarlborough, MAPHYSICAL REQUIREMENTS: While performing the duties of this job the employee is often required to stand, sit, use computers, read, write, type, use copy machines, file paperwork, use telephones, and utilize written and oral communication to interact with clients, co-workers, and customers. A function may be essential for any of several reasons, including: the job exists to perform that function, the employee holding the job was hired for his/her expertise in performing the function, or only a limited number of employees are available to perform that function.
Principal Scientist - CMC Statistician SanofiPrincipal Scientist - CMC StatisticianFramingham, MA$122.25–$176.58 / hourAs part of the development of Sanofi's pharmaceutical products, the R&D Data Sciences department and more specifically the Statistics department for the Chemical Manufacturing Control (CMC), CMC Statistics, is responsible for contributing to statistical support, modelling, digitalization, decision-making and filing of new product registration files. Contribute to developing state-of-the-art methodologies and statistical approaches on a variety of subjects needed for his/her field(s) of expertise, in partnership with other statisticians from the team and other groups of statisticians when appropriate.
Principal Scientist, Process Modeling, Digital Insights Merck & Co IncPrincipal Scientist, Process Modeling, Digital InsightsBoston, MA$173,200–$272,600 / yearThe successful candidate will play a technical leadership role in establishing engineering simulation as a core capability across DSCS partnering deeply with experimentalists, process engineers, and DS technical leads to translate first-principles model outputs into actionable CMC decisions. In this Principal Scientist role, the successful candidate will apply first-principles engineering, computational fluid dynamics (CFD), and physics-based simulation to bring predictive rigor to scale-up across a multi-modality pipeline from small to large molecules, with a current focus on biologics.
Principal Automation Software Engineer SanofiPrincipal Automation Software EngineerWaltham, MA$122.25–$176.58 / hourAbout you: Education: A Bachelor's Degree in Computer Science, Computer Engineering, Software Engineering, Information Systems, Electrical Engineering, Bioengineering, or a related field with a minimum of 5 years of relevant experience. The individual in this role will be responsible for developing, maintaining, and deploying software solutions that automate laboratory instruments, robotics, sample handling systems, and associated data workflows.
Associate Principal Scientist, Downstream Bioprocess Modeling, Digital Insights Merck & Co IncAssociate Principal Scientist, Downstream Bioprocess Modeling, Digital InsightsCambridge, MA$142,400–$224,100 / yearRequired Skills: Analytical Testing, Analytical Testing, Biochemistry, Cell Line Development, Chemical Engineering, Computer Simulations, Data Modeling Techniques, Detail-Oriented, Downstream Process Development, Downstream Processing, Drug Delivery Technology, Drug Development, Expression Vectors, Interpersonal Relationships, Kinetics, Laboratory Instrumentation, Leading Project Teams, Method Development, Model Development, Model Driven Design, Molecular Biology, Parameter Estimation, Perform Testing, Pharmaceutical Formulations, Pharmaceutical Process Development {+ 9 more}. The successful candidate will play a technical leadership role in embedding mechanistic downstream modeling into DSCS decision-making-partnering closely with DSP scientists, process engineers, and DS technical leads to translate model outputs into actionable purification and manufacturing decisions.
Principal Data & Analytics Engineer CuraleafPrincipal Data & Analytics EngineerWakefield, MA$145,000–$160,000 / yearAs a high-growth cannabis company known for quality, expertise and reliability, the Company, and its brands, including Curaleaf, Select, Grassroots, Find, and Anthem provide industry-leading service, product selection and accessibility across the medical and adult-use markets. Curaleaf Holdings, Inc. (TSX: CURA) (OTCQX: CURLF) ("Curaleaf") is a leading international provider of consumer products in cannabis with a mission to enhance lives by cultivating, sharing, and celebrating the power of the plant.