Staff Software Engineer Asimov IncStaff Software EngineerBoston, MAYoull join an interdisciplinary team that works directly with scientists, synthetic biologists, and computational biologists alongside your teammates in software engineering and product. Design GraphQL APIs for searching, editing and analyzing tens of thousands of genetic constructs using Python 3, SQLAlchemy and Strawberry.
Data Scientist - Computational Biology Penfield Search PartnersData Scientist - Computational BiologyWaltham, MAThe ideal candidate has hands-on experience with RNA sequencing data, strong computational biology expertise, and enjoys collaborating closely with experimental scientists to generate biological insights that advance therapeutic discovery. This individual will support drug discovery research by processing, analyzing, visualizing, and interpreting next-generation sequencing (NGS) datasets, with a strong emphasis on transcriptomics and long-read sequencing technologies.
Principal Scientist/Sr. Principal Scientist, Computational Chemistry & Molecular Design Antares TherapeuticsPrincipal Scientist/Sr. Principal Scientist, Computational Chemistry & Molecular DesignBoston, MassachusettsAs a member of a highly integrated team of medicinal chemists, machine learning scientists, structural biologists, biologists, and chemical biologists, you will apply and advance the full range of modern computational methods — structure- and ligand-based design, molecular dynamics, free energy perturbation (FEP), and machine-learning / generative approaches — to assess and prioritize targets, identify high-quality starting points, and drive lead optimization toward development candidates. Serve as the computational chemistry function lead on programs, providing integrated leadership across target validation, hit identification, hit-to-lead, and lead optimization for multiple small-molecule programs.
Postdoctoral Fellow - PKPD Modelling, Lung-on-Chip Harvard UniversityPostdoctoral Fellow - PKPD Modelling, Lung-on-ChipBoston, MA$72,000–$77,500 / yearD., Founding Director at the Wyss Institute for Biologically Inspired Engineering at Harvard University seeks outstanding postdoctoral applicants with expertise in lung biology, cancer biology, and/or infectious disease to join an interdisciplinary team of biologists and engineers using human Lung Organ Chips to study lung cancer progression, tumor-immune interactions, and respiratory infections in a clinically relevant context. In addition to carrying out translational research with these microphysiological models, the successful candidate will be expected to apply for fellowship funding, contribute to the writing of grants and manuscripts, participate in teaching and mentoring of lab members as needed, and otherwise contribute to overall lab operations.
Senior Research Associate ProximaSenior Research AssociateBoston, MassachusettsThis role will focus on running XLMS sample preparation and LC-MS workflows end-to-end, learning routine maintenance of our next-generation mass spectrometry instrumentation, and contributing to the scale-up of proteome-wide interaction mapping. In parallel, Proxima is developing an advanced structural interactomics platform built on proprietary cross-linking mass spectrometry (XLMS) technology and a lab equipped with next-generation mass spectrometry instrumentation.
HMS - Associate in Biomedical Informatics (Baym Lab) Harvard UniversityHMS - Associate in Biomedical Informatics (Baym Lab)Cambridge, MAThe candidate will work with a multi-disciplinary team of computational biologists, evolutionary biologists, and microbiologists to conduct research on mobile genetic element genetics and biology using a mixture of synthetic, genetic, and computational tools. The Department of Biomedical Informatics (DBMI) at Harvard Medical School and the Baym Lab are seeking an Associate, postbacalaureate researcher, with experience in the evolution of mobile genetic elements.
Senior Scientist, Systems Biology SanofiSenior Scientist, Systems BiologyCambridge, MA$100.50–$145.17 / hourMain Responsibilities: Analyze and leverage spatial and single-cell multiomic data to delineate pathogenic cell states and tissue microenvironments, generating actionable mechanistic insights and novel target hypotheses that directly inform drug discovery decisions. About You: PhD completed by August 2026 in systems biology, computational biology, computer science, applied mathematics, or a related field with 0-3 years of relevant academic or industry experience.
Principal Scientist, Computational Biology Bristol-Myers Squibb CoPrincipal Scientist, Computational BiologyMARemote$166,770–$202,086 / yearIPS conducts applied computational research in areas that include genomic, structural and molecular informatics, computational and systems biology, patient selection and translational biomarker research, and broader fields including knowledge science, epidemiology and machine learning-across the full lifecycle of drug discovery and development and across all therapeutic areas at BMS. Hands on experience analyzing and integrating high-dimensional molecular datasets such as multi-omics (RNA-seq, ATAC-seq, proteomics, ChIP-seq/CUT&RUN), single cell profiling (CITE-seq, scATAC-seq, perturb-seq) and/or spatial profiling to derive novel biological insights.
Senior Scientist, AI Computational Structural Biology Bristol-Myers Squibb CoSenior Scientist, AI Computational Structural BiologyMA$148,210–$179,601 / yearRequirements - Technical Skills & Experience: AI/ML & Deep Learning: Proven experience developing and deploying AI/ML models in biological or biochemical contexts, with proficiency in deep learning architectures for structural data (GNNs, equivariant neural networks, transformers, diffusion, flow matching) using Python and relevant libraries (PyTorch, JAX, RDKit, ESM/fair-esm, Biopython, etc.). IPS conducts applied computational research in areas that include genomic, structural and molecular informatics, computational and systems biology, patient selection and translational biomarker research, and broader fields including knowledge science, epidemiology and machine learning-across the full lifecycle of drug discovery and development and across all therapeutic areas at BMS.
Sr. Director/VP, Biology Manifold Bio IncSr. Director/VP, BiologyBoston, MA$240,000–$340,000 / yearEducation and Experience: PhD in molecular biology, biochemistry, pharmacology, neuroscience, pathology, or a closely related discipline; 10+ years of biopharma R&D experience for VP level, or 7+ years for Senior Director level. Provide effective leadership for 1-2 cross-functional drug discovery project teams, integrating biology, therapeutic discovery/engineering, pharmacology, and preclinical development expertise.
Potentially a good fit for PTI? Convergent ResearchPotentially a good fit for PTI?Watertown, MANew career opportunities Members of PTI will be supported with industry-level resources to lead research projects and disseminate their discoveries and innovations to the broader biomedical community through frequent publications, presentations, and submissions to public data portals. As an incubator within the Schmidt Futures Network, we identify high-impact scientific or technical research and development opportunities, ultimately defining and launching these projects as Focused Research Organizations.
HMS - Postdoctoral Fellow in Biomedical Informatics (Park Lab) Harvard UniversityHMS - Postdoctoral Fellow in Biomedical Informatics (Park Lab)Cambridge, MAThe Research Fellow will be responsible for the code base supporting the large-scale genomic processing and analysis pipelines at the SMaHT Data Analysis Center that manages multi-omic data, e.g., Illumina, PacBio, ONT, Whole Genome Sequencing (WGS), RNA-Seq. We are looking for a highly skilled bioinformatics postdoctoral Research Fellow who specializes in researching, designing, developing, deploying, and maintaining scalable bioinformatics pipelines on cloud-based infrastructure.
Software Engineer, UI Watershed Informatics, Inc.Software Engineer, UIBoston, MAJoin a team that's intellectually curious with a bias for action, headquartered in Cambridge, Massachusetts, composed of people who have come together to enable outcomes while empowering the research of all those committed to changing lives - all while bringing transformational change to a $40 billion industry. Focusing on developing new features with ReactJS and NextJS, you'll consult with biologists and our bioinformaticians to understand the stages of genomic analysis, and create an interface that is exceptionally flexible and useful for scientists.
Sr. Director/Vp, Biology Manifold BioSr. Director/Vp, BiologyBoston, MA$240,000–$340,000 / yearEducation and Experience: PhD in molecular biology, biochemistry, pharmacology, neuroscience, pathology, or a closely related discipline; 10+ years of biopharma R&D experience for VP level, or 7+ years for Senior Director level. Manifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively multiplexed in vivo screening to unlock tissue-targeted medicines and organism-scale models of living systems.
Director, Computational Biology Ionis Pharmaceuticals IncDirector, Computational BiologyBoston, MA$157,542–$206,759 / yearWith multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals. Well-suited candidates will have a systems level approach to understanding biology that harmonizes multiple interacting functional inputs including transcriptional regulation, protein function and larger order (cellular and tissue) biochemical relationships.
Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity And Related) Amgen Inc.Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity And Related)Cambridge, MA$182,465–$246,865 / yearThe Computational Biology group in the Center for Technology and Innovation (CfTI) within the Precision Medicine organization at Amgen is seeking a highly motivated Computational Biologist with expertise in analyzing clinical biomarker data, including but not limited to metabolomics, genomics, transcriptomics, proteomics, spatial-omics, flow cytometry, immunoassays, and other biomarker assays. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity and Related) Amgen IncAssociate Director - Computational Biology (Cardiovascular, Metabolic, Obesity and Related)Cambridge, MA$182,465–$246,865 / yearThe Computational Biology group in the Center for Technology and Innovation (CfTI) within the Precision Medicine organization at Amgen is seeking a highly motivated Computational Biologist with expertise in analyzing clinical biomarker data, including but not limited to metabolomics, genomics, transcriptomics, proteomics, spatial-omics, flow cytometry, immunoassays, and other biomarker assays. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Senior/Principal Scientist, MPN Biology, Translational Sciences PharmaEssentia CorpSenior/Principal Scientist, MPN Biology, Translational SciencesBEDFORD, MASummary of Key Responsibilities: Study Design and Execution: Lead the design, planning, and execution of POC and translational studies in healthy and MPN mouse models and primary human cellular and tissue systems to generate comprehensive pharmacology and biomarker data packages including MOA and differentiation from competitor programs. Founded in 2003 by a team of Taiwanese American executives and renowned scientists from U.S. biotechnology and pharmaceutical companies, today we are listed on the Taipei Exchange (TPEx: 6446) and are expanding our global presence with operations in the U.S., Japan, China and Korea, along with a world-class biologics production facility in Taichung.
Senior/Principal Scientist, MPN Biology, Translational Sciences PharmaEssentia U.S.A.Senior/Principal Scientist, MPN Biology, Translational SciencesBEDFORD, MAFull timeFounded in 2003 by a team of Taiwanese American executives and renowned scientists from U.S. biotechnology and pharmaceutical companies, today we are listed on the Taipei Exchange (TPEx: 6446) and are expanding our global presence with operations in the U.S., Japan, China and Korea, along with a world-class biologics production facility in Taichung. In this position, you will utilize your expertise in MPN stem cell biology, driver mutation signaling pathways, in vivo MPN mouse models and biomarker discovery to guide proof-of-concept (POC) studies, drug development and biomarker strategies, optimize dosing regimens, and ensure the safety and efficacy of investigational drugs.
Senior/Principal Scientist, Computational Biology Cellular IntelligenceSenior/Principal Scientist, Computational BiologyBoston, MassachusettsWe take a full-stack approach, generating perturbation data at over 1,000x the efficiency of conventional methods, capturing millions of time-resolved treatment combinations per experiment, and training large-scale models that generalize across contexts to enable rational protocol design for regenerative medicine, context-specific drug effect prediction, and systematic disease modeling. As a Senior Computational Biologist, your core job is to discover novel biological insight from rich biological data across transcriptomic datasets, including data from our own novel microfluidic-based assays and therapeutic programs, and to ground our AI and machine learning efforts in deep expertise in transcriptomics and biology.