Perform comprehensive clinical assessments prior to, during, and following apheresis treatments, including evaluating vital signs, neurological status, fluid balance, and laboratory parameters (e.g., CBC, electrolytes, ionized calcium, coagulation profiles). Monitor patients closely for procedural tolerance and acute complications, implementing prompt interventions for citrate anticoagulation effects (including IV/oral calcium replacement protocols), hypovolemia, transfusion reactions, or vasovagal events.