NewPrincipal Scientist, Clinical Biomarker, Immunology & Immuno-Oncology (Hematology) Legend Biotech USPrincipal Scientist, Clinical Biomarker, Immunology & Immuno-Oncology (Hematology)Somerset, New JerseyLeverage advanced single-cell technologies (e.g., scRNA-seq) to deeply profile immune cell compartments, particularly T-cell states and exhaustion markers, to inform patient stratification and biomarker hypotheses. Our research spans chimeric antigen receptor T-cell (CAR-T), T-cell receptor (TCR-T), natural killer (NK) cell-based therapies, and other emerging platforms designed to transform the treatment of serious diseases.
Principal Performance Java Test Enigineer BlockHiresPrincipal Performance Java Test EnigineerJersey City, New JerseyWe are uniquely positioned at the center of global trading activity, processing over 100 million financial transactions every day, pioneering industry-wide, post-trade solutions and maintaining multiple data and operating centers worldwide. This highly technical position is responsible for the performance engineering of DTCC distributed computing environments and providing analytical stress evaluations of applications/systems and service level compliance using statistical, analytical, and simulation methods.
Principal Product Engineer, Data Applications Kairon HealthPrincipal Product Engineer, Data ApplicationsNew York, New YorkOur platform parses, normalizes, and connects data across fragmented systems (EHRs, payers, CRMs, and qualitative sources) so practice leaders can make clear, confident decisions that improve outcomes and drive sustainable growth. You’ll thrive here if you’re as excited about what you build as why you’re building it: an engineer who understands product trade-offs, can shape features from user requirements, and enjoys turning messy data into meaningful, elegant applications.
Senior/Staff/Principal AI/ML Engineer - Threat Detection Engineering AppGate Cybersecurity, Inc.Senior/Staff/Principal AI/ML Engineer - Threat Detection EngineeringNew York, NY$180,000–$275,000 / yearMLOps & Productionization: Experience building and operating scalable MLOps platforms for AI/ML systems, including model lifecycle management, CI/CD for ML pipelines, feature stores, automated retraining, model monitoring/drift detection, experiment tracking, and deployment orchestration using Kubernetes, MLflow, Kubeflow, SageMaker, or equivalent tooling in high-throughput production environments. • Your engineering work will directly enable next-generation capabilities, including: • Threat Detection Engine: Build advanced detections to identify threats early, including identity compromise, privilege escalation, impossible travel, and data exfiltration across identity, network, device, and session telemetry.
Senior/Staff/Principal SWE- Observability Engineering AppGate Cybersecurity, Inc.Senior/Staff/Principal SWE- Observability EngineeringNew York, NY$180,000–$275,000 / yearYour engineering work will directly enable next-generation capabilities, including: • OpenTelemetry-Native Telemetry Fabric: Logs and distributed traces from clients, controllers, gateways, and connectors — all correlated by session, user, device, and trace ID across the full ZTNA flow. It emits high-fidelity, correlated telemetry across every AppGate component, is OpenTelemetry-native, engineered for 100M+ events per day, and designed to stream into Datadog, Splunk, Nexthink, Elastic, or any OTLP-compatible backend.
Principal Applied Scientist Elevance Health IncPrincipal Applied ScientistNew York, NY$214,192–$350,496 / yearMinimum Requirements: Requires an MS or PhD in Computer Science, Machine Learning, Statistics, Applied Mathematics, Operations Research, Engineering, Data Science, Economics, or a related quantitative discipline and a minimum of 10 years of experience in machine learning, data science, artificial intelligence, advanced analytics, or related technical fields; or any combination of education and experience which would provide an equivalent background. Preferred Skills, Capabilities and Experiences: Experience with generative artificial intelligence, large language models, reinforcement learning, information retrieval, forecasting, recommender systems, optimization, causal inference, experimentation, or decision intelligence preferred.
NewPrincipal Technical Program Manager Oracle CorpPrincipal Technical Program ManagerNY$97,500–$209,500 / yearSeven or more years of experience in technical program management, security program leadership, cloud delivery, compliance engineering, security engineering, or a related technology field, including responsibility for complex cross-organizational programs. Demonstrated experience leading an end-to-end FedRAMP certification or authorization, federal Authority to Operate, or comparably complex regulated cloud-assurance program from strategy or readiness through assessment, remediation, decision, and ongoing monitoring.
Principal Software Engineer, Developer Acceleration Release Engineering HubSpot IncPrincipal Software Engineer, Developer Acceleration Release EngineeringNY$266,200–$425,900 / yearThe Principal Software Engineer in Developer Acceleration will help determine how that platform evolves, how AI changes what''s possible in software delivery, and how thousands of engineers across HubSpot ship better software, faster. This is a rare opportunity to work on infrastructure problems that very few engineers have encountered - at a scale that demands novel approaches - while helping to define what AI-native release engineering looks like in practice.
Principal Product Designer - Market Data Dow Jones & Co IncPrincipal Product Designer - Market DataNew York, NY$150,000–$200,000 / yearYou Will: Own the design strategy for the Market Data platform across our financial brands -setting a coherent, multi-year direction for quotes, charting, watchlists, screeners, portfolios, and data visualization that spans The Wall Street Journal, Barrons, MarketWatch, and IBD, and connecting it to measurable outcomes like engagement, retention, and revenue. About the Role: As Principal Product Designer - Market Data, you will own the design strategy for our Market Data platform-the real-time quotes, charting, watchlists, screeners, and visualization systems that power how millions of people read and act on financial markets across The Wall Street Journal, Barrons, MarketWatch, and Investors Business Daily.
Principal ASIC Design Verification Engineer K2 Space CorpPrincipal ASIC Design Verification EngineerNY$190,000–$285,000 / yearBacked by $450M from leading investors including Altimeter Capital, Redpoint Ventures, T. Rowe Price, Lightspeed Venture Partners, Alpine Space Ventures, and others - with an additional $500M in signed contracts across commercial and US government customers - we're mass-producing the highest-power satellite platforms ever built for missions from LEO to deep space. Engineered to survive the harshest radiation environments and to fully capitalize on today's and tomorrow's massive rockets, K2 satellites deliver unmatched capability at constellation scale and across multiple orbits.
Principal SASE Engineer Citizens Financial Group IncPrincipal SASE EngineerNJ$142,000–$175,000 / yearDesign, deploy, and support Netskope services, including Secure Web Gateway (SWG), Cloud Access Security Broker (CASB), Zero Trust Network Access (ZTNA), Data Loss Prevention (DLP), Cloud Firewall, and related Security Service Edge (SSE) capabilities. The ideal candidate will possess deep hands-on expertise with Netskope technologies, strong network and security engineering experience, and a demonstrated ability to lead large-scale enterprise deployments.
Principal Product Manager - Threat Detection Content (Hybrid) CrowdStrike IncPrincipal Product Manager - Threat Detection Content (Hybrid)New York, NY$160,000–$250,000 / yearIn this role, you will bring your in-depth knowledge of the Threat Detection market (including Endpoint, Cloud, and other core pillars) to help guide the evolution of CrowdStrike's visibility, detection, and prevention technologies. About the Role: The Product Management team is seeking an experienced Principal Product Manager who is technical, collaborative, and truly excited about building great security products.
Principal / Senior Partner Technical Enablement Lead, Workday Wellness Workday IncPrincipal / Senior Partner Technical Enablement Lead, Workday WellnessNew York City, NY$173,400–$260,200 / yearAs the Partner Technical Enablement Lead for Workday Wellness, you will own the technical journey for our Wellness Partners, ensuring they understand Workday HCM/Benefits functionality, master our API capabilities, and are fully equipped to guide enterprise customers through successful product deployments. Equip partners with both the technical expertise and program management frameworks required to lead customer deployments: Coach partners on best practices across all deployment phases (discovery, design, build, test, deploy, and post go-live).
Principal Product Manager, Frame.io ADOBE IncPrincipal Product Manager, Frame.ioNew York, NY$194,800–$282,100 / yearAdobe's industry-leading offerings including Adobe Acrobat Studio, Adobe Express, Adobe Firefly, Creative Cloud, Adobe Experience Platform, Adobe Experience Manager, and GenStudio enable people and businesses to turn ideas into impact, powered by AI and driven by human ingenuity. We're investing heavily in growing Frame.io's global reach, deepening its role as the creative hub within Adobe's ecosystem, and building AI-powered workflows that make creative work radically faster, more aligned, and more fun.
Principal Engineer Planful Inc.Principal EngineerNY$325,000–$375,000 / yearConcurrency & scaling: Build and maintain high-performance microservices using Java (Micronaut or Spring Boot) with Project Loom (Virtual Threads) to handle massive concurrent read loads. You will own the internals of the query engine at the heart of a next-generation financial planning platform - the layer where compiler theory, columnar database performance, and multi-dimensional semantics converge.
Principal Business Consultant, Front Office SimCorp ASPrincipal Business Consultant, Front OfficeNew York, NY$163,520–$245,280 / yearYou will normally be working full-time on implementation projects, which require your special expertise in the Front Office area - including order and trade management, multi-asset class trading, and portfolio management - and you will be responsible for all aspects of the project stream. With typically 5-8 years of experience in consulting or a related field, this role leads projects autonomously, provides strategic insights, and applies specialized expertise to design and implement complex SimCorp Dimension solutions.
Principal Product Manager, Charlotte AI Platform (Hybrid) CrowdStrike IncPrincipal Product Manager, Charlotte AI Platform (Hybrid)New York, NY$160,000–$250,000 / yearDrive Cross-Functional Delivery: Work closely with multiple internal stakeholders-including engineering, data science, and business units-to deeply understand their use cases and translate them into actionable product features. We base all employment decisions--including recruitment, selection, training, compensation, benefits, discipline, promotions, transfers, lay-offs, return from lay-off, terminations and social/recreational programs--on valid job requirements.
Principal Demand Generation Lead Clasp Group IncPrincipal Demand Generation LeadNYRemote$150,000–$180,000 / yearLocation: Remote (US), EST/CST time zones. Principal Demand Generation Lead.
Principal Solution Sales Advisor Dassault Systemes SEPrincipal Solution Sales AdvisorNew York, NYRemote$116,250–$155,000 / yearCelebrating over 25 years of ground-breaking technological innovation across more than 38,000 trials and 12 million patients, Medidata offers industry-leading expertise, analytics-powered insights, and one of the largest clinical trial data sets in the industry. Support marketing teams in establishing and managing quarterly Product Marketing activities (including, but not limited to - white papers, press releases, search engine optimization, case studies, etc.).
Principal Product Manager - AI Models PointClickCare Technologies IncPrincipal Product Manager - AI ModelsNYRemote$170,200–$189,200 / yearContribute to strategy and multi-year AI Platform roadmap to enable products and users to enable providers to deliver exceptional care, Collaborate with Engineering, User Experience, Technical Writers, and other product managers leveraging modern agile processes and Design Thinking. Position Summary: As a Principal Product Manager at PointClickCare, you contribute to PointClickCare's vision and strategy for operationalizing AI Models, define roadmaps for AI Models in the broader AI platform, and drive execution to ensure overall success with AI Models across the entire product portfolio.