Metabolite extraction: Performing metabolite extraction of thousands of samples/year using a variety of solvents, as well as directly customizing protocols for diverse, complex sample types including soil, bacteria, plant, fungal, environmental, aqueous (including high salt, diverse pH) samples, optimizing solvents (methanol, water, ethyl acetate, chloroform, etc.) and methods. Method development: Developing and optimizing new ESI-LC-MS/MS methods (MS settings, mobile phases, chromatography, column, etc) to target specific metabolite classes or metabolites such as sugars, lipids, pigment and implementing these in high-throughput metabolomics workflows, as well as incorporating custom data acquisition software workflows (including AcQuireX for iterative MSMS) and similar technologies.