Associate Scientist-II Integrated Resources, IncAssociate Scientist-IICambridge, MassachusettsFull timeThe successful candidate will have hands-on experience with a variety of biochemical methods relevant for the study of neurodegenerative diseases and the ability to utilize these methods for target engagement studies to support drug discovery and development projects. As Associate Scientist II, the expectation is that the incumbent is capable of planning and executing experiments with limited supervisorial oversight including the analysis and interpretation of the experimental results to achieve agreed upon objectives.
Advanced Process Analytics Scientist Integrated Resources, IncAdvanced Process Analytics ScientistCambridge, MassachusettsContractorThis includes but not limited to developing tools for deeper understanding of the underlying biological phenomena that lead to differences in product quality (e.g., via metabolic flux modeling, proteomics modeling, bio-informatics); develop robust spectral models correlating to valuable metabolites, cell mass, and product quality attributes (e.g., chemometric models for NIR, Raman). To reach that goal, we are exploring the application of state of the art data science and machine learning while leveraging available process knowledge and a wealth of development and manufacturing data to build end to end product quality predictive meta-models.
Analytical Development Senior Scientist Vertex Pharmaceuticals, IncAnalytical Development Senior ScientistBoston, MA$122,400–$183,600 / yearThe position is part of the Chromatography Subject Matter Expert (SME) team, focused on small molecules and synthetic peptides/oligonucleotides, with particular emphasis on drug substance, drug product intermediates, and drug product. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
Research Leader / Senior Scientist (Medicinal Drug Design), Cambridge, MA Isomorphic LabsResearch Leader / Senior Scientist (Medicinal Drug Design), Cambridge, MACambridge, MAProven track record of project leadership / leading medicinal chemistry efforts on drug discovery projects, demonstrating significant contributions to project progression (ideally from hit identification through to lead optimisation or candidate nomination), with familiarity of optimisation of ADME properties. Rapidly drive drug discovery programs to value inflection points by deploying your knowledge of modern discovery principles and synthetic organic chemistry, taking ownership as either an overall Project Lead or Medicinal Chemistry Lead.
Senior Scientist, Translational Research Triveni BioSenior Scientist, Translational ResearchWatertown, MassachusettsOur lead antibody program (TRIV-509) targets kallikreins 5 and 7 (KLK5/7) to directly impact skin barrier function, inflammation, and itch – providing a meaningful and much needed potential treatment option for patients with atopic dermatitis and other barrier disorders. Familiarity or expertise in mechanistic cell-based and cell-free assays to investigate type 2 immunity, including immune cells, mast cells, IgE biology, cytokine modulation, and other relevant pharmacodynamic readouts.
Research Leader / Senior Scientist (In vitro / Cellular Pharmacology), Cambridge, MA Isomorphic LabsResearch Leader / Senior Scientist (In vitro / Cellular Pharmacology), Cambridge, MACambridge, MAThese are exciting opportunities to work closely with world-leading ML and drug discovery experts to develop imaginative new ways to test biological hypotheses, building a deep mechanistic understanding of drug target interactions to drive our projects forward. These roles are ideal for experienced in vitro pharmacologists with significant working knowledge of biophysical, biochemical and/or cell-based functional assays, and extensive experience of providing quantitative in vitro pharmacology expertise within drug discovery projects.
Research Leader / Senior Scientist (In vivo Pharmacology & Translational Sciences), Cambridge, MA Isomorphic LabsResearch Leader / Senior Scientist (In vivo Pharmacology & Translational Sciences), Cambridge, MACambridge, MAAct as a vital bridge between computational prediction and experimental reality, collaborating closely with: ML and Data Science Teams: To translate in silico predictions into physical validation protocols and provide clean data loops to train future models, iteratively improving the predictive accuracy of our proprietary drug design platform. These are exciting opportunities to work closely with world leading ML and drug discovery experts to develop imaginative new ways to test biological hypotheses, building a deep mechanistic understanding of drug target interactions in disease to drive our projects forward.
NewResearch Leader / Senior Scientist (In Vitro / Cellular Pharmacology), Cambridge, MA Isomorphic LabsResearch Leader / Senior Scientist (In Vitro / Cellular Pharmacology), Cambridge, MACambridge, MAClassification of protected categories is as follows: A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability. These roles are ideal for experienced in vitro pharmacologists with significant working knowledge of biophysical, biochemical and/or cell-based functional assays, and extensive experience of providing quantitative in vitro pharmacology expertise within drug discovery projects.
NewResearch Leader / Senior Scientist (In Vivo Pharmacology & Translational Sciences), Cambridge, MA Isomorphic LabsResearch Leader / Senior Scientist (In Vivo Pharmacology & Translational Sciences), Cambridge, MACambridge, MAAct as a vital bridge between computational prediction and experimental reality, collaborating closely with: ML and Data Science Teams: To translate in silico predictions into physical validation protocols and provide clean data loops to train future models, iteratively improving the predictive accuracy of our proprietary drug design platform. Classification of protected categories is as follows: A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.
Distinguished Scientist, Transgenic Model And Technology SanofiDistinguished Scientist, Transgenic Model And TechnologyCambridge, MA$178,500–$257,833.33 / yearAs the Global Head of Transgenic Biology, you will ensure our organization remains at the forefront of technical developments in genome engineering, enabling breakthrough discoveries in immunology, immuno-inflammation, rare diseases, neuroscience, and oncology. Deep expertise in developing transgenic animal models, including engineering diverse genetic alleles using CRISPR/Cas9, Cas12, base editors, prime editors, and other advanced genome engineering systems.
Principal Scientist, Computational Protein Design ModernaTXPrincipal Scientist, Computational Protein DesignCambridge, MassachusettsWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. This individual will work in close partnership with structural biology, directed evolution, immunology, translational science, and program teams to advance platform innovation and therapeutic programs across Moderna’s Research and Early Development portfolio.
Sr. Scientist, Delivery Sciences ModernaTXSr. Scientist, Delivery SciencesCambridge, MassachusettsWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. In this role, you will advance the science of LNP self-assembly, engineer delivery systems for small- and large-molecule payloads beyond the liver and leverage state-of-the-art analytical techniques to establish structure–function relationships that drive biological performance.
NewData Scientist ModernaTXData ScientistCambridge, MassachusettsSupport and execute on research projects that leverage internal and external assay data to impact teams, processes, and projects in Biological Sciences, RNA Sciences, Chemistry and Delivery Sciences, and Bioinformatics, via data analysis and visualization, algorithm development, machine learning, and experimental design. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
NewAI Research Scientist - PhD - AI Trainer MercorAI Research Scientist - PhD - AI TrainerBoston, MassachusettsRemote$66–$84 / hourFor details about the interview process and platform information, please check: https://talent.docs.mercor.com/welcome. Strong command of graduate-level CS theory , algorithms , systems design , and/or machine learning .
Senior Associate Scientist, Bioprocess Analytics SanofiSenior Associate Scientist, Bioprocess AnalyticsFramingham, MA$75–$108.33 / hourBachelor's degree in Analytical Chemistry, Biochemistry, Biology, Biotechnology, Bioengineering or a related discipline with 3-5 years of relevant experience, or master's degree with 1-3 years of relevant experience in research laboratory or biopharma/biotech company (co-ops experience in biopharma/biotech is acceptable). Strong background in LC-MS/MS techniques for protein post-translational modification (PTM) identification and quantitation, glycan analysis and metabolites analysis (amino acids and vitamins), with proficient instrumental operation and troubleshooting skills on Waters or Thermo instrumentation.
Clinical Scientist - Oncology 3316 Takeda Development Center AmericasClinical Scientist - OncologyBoston, MassachusettsSuccessfully contributes to interactions with regulatory authorities / agencies and key opinion leaders relevant to assigned compound and participate in meetings with representatives of the regulatory organizations and the identification / contact / maintenance of strong Company relationships with key opinion leaders. Bachelor’s degree and 6 years, master’s degree and 4 years, PharmD degree and 2 years, or PhD and 1 year of clinical research and/or clinical development experience within the pharmaceutical industry, CRO health-related consulting company, or biomedical/clinical experience within academia (or a combination of afore mentioned.) .
Associate Scientist, Potency Method Development 3316 Takeda Development Center AmericasAssociate Scientist, Potency Method DevelopmentLexington, MassachusettsReporting to the Head of the Cell-Based Potency Assay Development team within Analytical Development, Biologics, you will be responsible for designing, developing, qualifying, and transferring cell-based and ligand binding potency assays and related methods for biologics programs. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.
Clinical Scientist, Ophthalmology SanofiClinical Scientist, OphthalmologyCambridge, MA$148,500–$214,500 / yearThe primary purpose of the Clinical Scientist's position is to assist/support the Clinical Research Director in the medical/scientific contribution for ophthalmology clinical studies, including: supporting operational activities pertaining to protocol development (such as Informed Consent and committee charters), validation and clinical case review of study data, review of study plans and draft study reports/publications for accuracy, literature review and analysis, and preparation of responses for investigators, study teams, ethics committees, or regulatory authorities. Contribute to preparation and/or review of documents related to studies requiring scientific background (submission portfolio, abbreviated protocol/protocol/amended protocol, patient written information, presentations/communications to internal or external partners, study plans, study reports, trial disclosure form).
Associate Scientist, Biologics Characterization 3316 Takeda Development Center AmericasAssociate Scientist, Biologics CharacterizationLexington, MassachusettsYou will bring hands-on laboratory experience, technical curiosity, and the ability to develop expertise in one or more characterization platforms such as LC-MS, peptide mapping, intact mass analysis, glycan analysis, UPLC/HPLC fractionation, AUC, CD, DSC, DLS, spectroscopy, or related protein characterization methods. What you bring to Takeda: Associate degree with 7+ years, bachelor’s degree with 5+ years, or master’s degree with 3+ years of relevant industry experience in analytical development, biologics characterization, protein chemistry, biochemistry, biophysics, analytical chemistry, or a related discipline.
Staff Applied Scientist, Search & Discovery Material BankStaff Applied Scientist, Search & DiscoveryBoston, MAFlexible Work Schedules : With business units and employees across the globe, Material Technologies has embraced a hybrid working model allowing department leaders to decide on the best approach for their respective teams, whether that be remote, in person, or a little of both. Real exploratory and experimental rigor : statistical modeling, experimental design, and hypothesis testing, plus comfort working in ambiguity where the right approach is not yet known.