Scientist 3, Immunology Genentech IncScientist 3, ImmunologySouth San Francisco, CA$103,400–$192,000 / yearThe candidate will be expected to work independently and collaboratively on pipeline projects and will be responsible for advancing exciting and novel research stage programs into early clinical development, providing both scientific and technical expertise and generating solid proof of concept data. Using state of the art techniques and technologies, the candidate will have the capacity to develop in vitro and in vivo skills to test the involvement of novel pathways and molecules in the pathogenesis of inflammatory diseases and to identify the mechanism of action (MOA) of new targets.
NewHybrid | Senior Pharmaceutical R&D Scientist — $65–$105/hour 24-MagHybrid | Senior Pharmaceutical R&D Scientist — $65–$105/hourSan Francisco, California$65–$105 / hourWe are sharing a specialised full-time opportunity for senior pharmaceutical and biotechnology R&D professionals with substantial experience across drug discovery, preclinical development, translational science, clinical development, regulatory affairs, or CMC. PhD or PharmD in a pharmaceutically relevant discipline such as Medicinal Chemistry, Organic Chemistry, Pharmacology, Molecular Biology, Pharmaceutical Sciences, Toxicology , or a related field.
Senior Scientist I, Cancer Genomics, Clinical Biomarker Development Revolution MedicinesSenior Scientist I, Cancer Genomics, Clinical Biomarker DevelopmentRedwood City, CaliforniaExperienced in the interrogation of DNA sequence data derived from tumor tissue, such as gene-panel, whole-exome or whole-genome data and downstream analytics (clonality estimates, copy number variation, chromosomal instability, mutational signatures, etc). Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS.
Senior Scientist, Biochemical and Cellular Pharmacology Genentech IncSenior Scientist, Biochemical and Cellular PharmacologySouth San Francisco, CA$124,300–$230,900 / yearDemonstrated expertise in receptor theory, signal transduction pathways, allosteric modulation, and biased signaling, along with hands-on experience across diverse GPCR assay platforms (e.g., cAMP, calcium flux, BRET/FRET, Beta-arrestin recruitment). Communicate Findings: Conduct comprehensive data analysis using advanced computational tools, and present high-quality scientific findings and strategic directions to internal stakeholders, project teams, and senior leadership.
Computational Clinical Scientist II, Clinical Bioinformatics Revolution MedicinesComputational Clinical Scientist II, Clinical BioinformaticsRedwood City, California$132,000–$166,000 / yearIntegrate multiple data sources including circulating tumor DNA, patient enrollment data, molecular profiling (RNA/DNA sequencing outputs), multiplex immunohistochemistry to identify and validate new biomarkers for candidate drugs. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS.
Scientist 3- Translational Medicine (Multiple Sclerosis & TR focused) Genentech IncScientist 3- Translational Medicine (Multiple Sclerosis & TR focused)South San Francisco, CA$100,400–$186,400 / yearAnalyze and interpret high-dimensional datasets from clinical samples, including single-cell RNA-seq, CITE-seq, bulk RNA-seq, spatial transcriptomics, and/or proteomics, to generate translational insights that support clinical development. This role sits at the intersection of clinical development and translational science - the ideal candidate is comfortable working with clinical biospecimens, interpreting high-dimensional datasets, and contributing findings that directly inform clinical trial design and molecule progression.
Scientist II, Analytical Development (Contract) VaxcyteScientist II, Analytical Development (Contract)San Carlos, CA$70–$78 / hourThis role performs routine and non-routine analytical assays using modern analytical techniques, supports method optimization and troubleshooting efforts, and contributes to continuous improvement initiatives with moderate supervision while partnering effectively with cross-functional teams. Strong hands-on experience with multiple analytical techniques, such as UV-Vis, HPLC, CE, SDS-PAGE, icIEF, Liquid chromatography, Mass Spectrometry, enzyme kinetics, colorimetric and fluorescent plate-based assays, ELISA, Western Blot, and PCR.
Senior Scientist I, Cancer Genomics, Clinical Biomarker Development Revolution Medicines IncSenior Scientist I, Cancer Genomics, Clinical Biomarker DevelopmentRedwood City, CA$149,000–$186,000 / yearExperienced in the interrogation of DNA sequence data derived from tumor tissue, such as gene-panel, whole-exome or whole-genome data and downstream analytics (clonality estimates, copy number variation, chromosomal instability, mutational signatures, etc). Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS.
NewComputational Scientist - Human Genetics - Remote Dawar Consulting, Inc.Computational Scientist - Human Genetics - RemoteSouth San Francisco, CARemoteThe role will focus on developing and applying analytical approaches to integrate and interpret genetic, genomic, and clinical data , including large-scale sequencing and single-cell datasets. Analyze large-scale genetic, genomic, and clinical datasets from internal studies, clinical trials, high-throughput screens, academic collaborations, industry partners, and public datasets.
NewSenior Machine Learning Scientist II, Drug Discovery Analytics Revolution MedicinesSenior Machine Learning Scientist II, Drug Discovery AnalyticsRedwood City, California$229,000–$269,000 / yearLeveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
NewComputational Scientist - HUman Genetics Dawar ConsultingComputational Scientist - HUman GeneticsSouth San Francisco, CaliforniaThe role will focus on developing and applying analytical approaches to integrate and interpret genetic, genomic, and clinical data , including large-scale sequencing and single-cell datasets. Analyze large-scale genetic, genomic, and clinical datasets from internal studies, clinical trials, high-throughput screens, academic collaborations, industry partners, and public datasets.
Associate Scientist II, Analytical Development, Raw Materials (Contract) VaxcyteAssociate Scientist II, Analytical Development, Raw Materials (Contract)San Carlos, CaliforniaPerform routine and non-routine analytical testing using modern analytical methods (e.g., LCMS, HPLC/UPLC, SEC, CE, UV-Vis, electrophoresis, plate-based assays, and other biochemical or biophysical techniques). This role will perform routine and non-routine analytical assays using modern analytical techniques and will contribute to method optimization, troubleshooting, and continuous improvement initiatives under supervision.
Computational Scientist II - Single Cell Genomics Dawar ConsultingComputational Scientist II - Single Cell GenomicsSouth San Francisco, CaliforniaThis role will involve analyzing large-scale sequencing datasets, developing computational pipelines, and collaborating with multidisciplinary teams to generate biological insights that support drug discovery. Analyze and interpret large-scale single-cell sequencing datasets (scRNA-seq) generated from high-content perturbation experiments.
Research Scientist Astera InstituteResearch ScientistAlameda, CaliforniaDesign and execute large-scale, multi-area neural recording experiments in awake, behaving subjects performing complex perceptual, working-memory, and higher-cognitive tasks, using high-density Neuropixels probes, chronic polymer probe arrays, two-photon imaging, and holographic optogenetics. Experimental work combines large-scale neural recordings, targeted stimulation, and behavioral design, working closely with computational, engineering, and software teams to translate biological insight into a detailed model of the brain that can guide causal perturbation experiments and inform new AI architectures.
Research Scientist, Life Sciences Chemistry Anthropic PBCResearch Scientist, Life Sciences ChemistrySan Francisco, CA$300,000–$320,000 / yearThis research continues many of the directions our team worked on prior to Anthropic, including: GPT-3, Circuit-Based Interpretability, Multimodal Neurons, Scaling Laws, AI & Compute, Concrete Problems in AI Safety, and Learning from Human Preferences. Working alongside AI researchers and engineers, you''ll drive experimental programs end to end and pressure-test AI-designed molecules and AI-proposed synthetic routes against real chemistry.
Senior Scientist I Cell Line Development AbbVie IncSenior Scientist I Cell Line DevelopmentSouth San Francisco, CAOverview: The Biologics CMC Development organization at AbbVie has a long and rich history of biologics development, leveraging comprehensive end-to-end CMC capabilities to advance complex biologic therapies, such as bi-specifics and novel modalities, from discovery through human clinical studies and eventual licensure. Apply a rigorous theoretical and practical understanding of recombinant protein expression from the genome to the protein - including genomic loci, epigenetics, transcription, mRNA stability, translation, the organelles and secretory machinery involved, and the engineering constraints specific to industrial CHO cell line development.
Computational Clinical Scientist II, Clinical Bioinformatics Revolution Medicines IncComputational Clinical Scientist II, Clinical BioinformaticsRedwood City, CA$132,000–$166,000 / yearThe company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Integrate multiple data sources including circulating tumor DNA, patient enrollment data, molecular profiling (RNA/DNA sequencing outputs), multiplex immunohistochemistry to identify and validate new biomarkers for candidate drugs.
Scientist I - Cell Screening and Pharmacology, Discovery Technology Nurix Therapeutics IncScientist I - Cell Screening and Pharmacology, Discovery TechnologyBrisbane, CA$127,000–$143,000 / yearThe scientist will design, execute, and analyze cellular assays that characterize DAC activity, and will partner closely with discovery biology, conjugation chemistry, analytical biochemistry, DMPK, and automation to advance candidates from early screening. Demonstrated experience designing and setting up in vitro pharmacology studies and screening cascades; prior know-how in building screening/assay cascades in the ADC or DAC field is preferred.
Scientist II, Delivery For Large Gene Insertion ProfluentScientist II, Delivery For Large Gene InsertionEmeryville, CAThe ideal candidate will have a strong track record of engineering molecular systems for mammalian cells, with expertise in gene editing, nucleic acid biochemistry, protein-nucleic acid engineering, or molecular virology. Design and execute hypothesis-driven experiments to identify and overcome barriers to donor template stability, intracellular trafficking, and nuclear availability.
Senior Scientist, Analytical Development VaxcyteSenior Scientist, Analytical DevelopmentSan Carlos, California$165,000–$193,000 / yearThis role designs and drives method development, performs and oversees routine and non-routine analytical assays using modern analytical techniques, and leads method optimization, troubleshooting, and continuous improvement initiatives with minimal supervision, including mentoring and technical guidance to junior team members. Reports to: Associate Director, Analytical Development Location: Onsite in San Carlos, CA Work Arrangement (may be adjusted based on business needs, job responsibilities, or changes to company policy): Onsite (minimum of 4 days per week onsite) Compensation: The compensation package will be competitive and includes comprehensive benefits and an equity component.