Discovery Postdoctoral Fellow, saRNA Biology Novartis AGDiscovery Postdoctoral Fellow, saRNA BiologyCambridge, MAThe program is intended for scientists immediately following their PhD training (PhD conferred in 2026 only).Demonstrated record of scientific achievement (publications, presentations, patents, or equivalent)Strong commitment to learning, innovation, and professional developmentStrong experimental background in RNA biology, gene regulation, transcriptional control, epigenetics, oligonucleotide therapeutics, or related areas. Opportunities to present research, publish in leading journals, and build an international scientific networkWe are entering a new era of biomedical research breakthroughs through the convergence of biology, technology, and artificial intelligence tools, and fellows are also supported in engaging with these emerging approaches.
NewScientist, Data Science AstraZeneca PlcScientist, Data ScienceWaltham, MA$91,008.80–$136,513.20 / yearThe successful candidate will leverage their data science expertise in mining large datasets to drive our efforts in target identification, mechanism of action (MOA) studies, and biomarker strategy development, with a particular focus on analyses related to the function and aging of the immune system. Ability to apply integrated generative protein design pipelines - from target-conditioned backbone generation through sequence design to computational fold validation - to support the development of novel therapeutic biologics with optimized specificity and developability properties.
Sr. Pathologist and Associate Medical Director Foundation Medicine IncSr. Pathologist and Associate Medical DirectorBoston, MA$272,000–$340,000 / yearThe role of Director, Molecular Pathology centralizes these responsibilities to one pathologist-supervision of molecular technologists (CAM and RTP); review of wet lab sequencing metrics and troubleshooting (CAM and RTP); supervision of bioinformatics case curation by computational biology operations (CBO) (CAM); ongoing reevaluation and updating of curation SOPs (CAM); ensuring adequate post-pipeline analysis training for members of CBO, TOCR, the MSL team, and pathology (CAM); collaboration with other FMI stakeholders (CAM and RTP); and final release of CGP results to patients and their physicians (CAM and RTP). In conjunction with the General Supervisors of the Molecular Lab Operations team, provide technical supervision of the Molecular Laboratory staff and testing: Review active and approve revisions to Molecular Lab SOPs & Work instructions in conjunction with QA, Regulatory, Lab Operations, and CLIA Laboratory Director to ensure high quality sequencing results.
Research Technology Specialist - Human Nutrition Research Center on Aging Tufts UniversityResearch Technology Specialist - Human Nutrition Research Center on AgingBoston, MassachusettsKnowledge and experience typically acquired by: Bachelor's Degree in biomedical engineering, computer science, data science, electrical engineering, bioinformatics, biostatistics, computational biology, applied mathematics, or a related quantitative or technical field. This position will contribute to data-rich research projects involving human studies, observational cohorts, lifestyle interventions, biomarker analytics, wearable and sensor-derived data, and high-dimensional omics datasets.
Research Scientist AI/ML Foundational Models 3316 Takeda Development Center AmericasResearch Scientist AI/ML Foundational ModelsBoston, MassachusettsThe actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. Implement state-of-the-art generative architectures (diffusion, score-based models, autoregressive transformers) for molecular generation, protein design, and multi-objective optimization.
Data Scientist Infectious Disease Tufts UniversityData Scientist Infectious DiseaseBoston, MassachusettsResearch topics include structural analysis of virus entry, viral evolution, viral oncogenes, intracellular bacterial pathogens, microorganisms that cause diarrhea and pneumonia, intracellular signaling, pathogen adhesion, genetic determinants involved in susceptibility to infection, vaccine development, and identification of novel antimicrobial agents. Demonstrated expertise in computational biology or a related quantitative discipline, including proficiency in programming languages such as Python, R, or MATLAB, and experience with machine learning frameworks, image analysis pipelines, or statistical modeling of large biological datasets.
Bioinformatician I RESEARCH NEUROLOGY MW Mass General BrighamBioinformatician I RESEARCH NEUROLOGY MWBoston, MassachusettsWorking under very general supervision, the Bioinformatics Analyst will have demonstrated independent design and innovation in one or more of the following areas of specialization: algorithm development, data analysis, quality assurance/testing, pipeline software/computing development, user interface design & report development, web-based application development, or report development. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success.
Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity and Related) Amgen IncAssociate Director - Computational Biology (Cardiovascular, Metabolic, Obesity and Related)Cambridge, MA$182,465–$246,865 / yearThe Computational Biology group in the Center for Technology and Innovation (CfTI) within the Precision Medicine organization at Amgen is seeking a highly motivated Computational Biologist with expertise in analyzing clinical biomarker data, including but not limited to metabolomics, genomics, transcriptomics, proteomics, spatial-omics, flow cytometry, immunoassays, and other biomarker assays. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Director, Computational Biology Ionis Pharmaceuticals IncDirector, Computational BiologyBoston, MA$157,542–$206,759 / yearWith multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals. Well-suited candidates will have a systems level approach to understanding biology that harmonizes multiple interacting functional inputs including transcriptional regulation, protein function and larger order (cellular and tissue) biochemical relationships.
NewSr. Scientist, Immune Repertoire Discovery ModernaTXSr. Scientist, Immune Repertoire DiscoveryCambridge, MassachusettsWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. This is a highly collaborative, hands-on role for a scientist who is excited to build and refine discovery workflows, generate high-quality biological datasets, and translate complex immune profiling results into actionable insights for therapeutic research.
NewSenior Scientist, Translational Computational Biology Bristol-Myers Squibb CoSenior Scientist, Translational Computational BiologyMA$148,210–$179,601 / yearSpatial biology: hands-on experience with spatial transcriptomics (e.g., Visium, Xenium, CosMx, GeoMx, MERFISH) and/or spatial proteomics and multiplex immunofluorescence (e.g., Lunaphore COMET, RareCyte Orion, Akoya), including cell segmentation, phenotyping, and neighborhood or spatial statistics; familiarity with the analysis stack (Squidpy, SpatialData, scverse) and with digital pathology tooling (HALO, QuPath). What you will have to work with: Clinical and multi-modal patient-derived datasets from BMS's industry-leading early-stage clinical studies in oncology: the molecular and clinical biomarker data generated by our own early-phase trials, spanning RNA-seq, WES, TCR-seq, ctDNA and CTC, together with flow cytometry, cytokine profiling, IHC, and proteomics.
Senior/Principal Scientist, Computational Biology Cellular IntelligenceSenior/Principal Scientist, Computational BiologyBoston, MassachusettsWe take a full-stack approach, generating perturbation data at over 1,000x the efficiency of conventional methods, capturing millions of time-resolved treatment combinations per experiment, and training large-scale models that generalize across contexts to enable rational protocol design for regenerative medicine, context-specific drug effect prediction, and systematic disease modeling. As a Senior Computational Biologist, your core job is to discover novel biological insight from rich biological data across transcriptomic datasets, including data from our own novel microfluidic-based assays and therapeutic programs, and to ground our AI and machine learning efforts in deep expertise in transcriptomics and biology.
Principal Scientist, Antibody Discovery and Engineering ModernaTXPrincipal Scientist, Antibody Discovery and EngineeringCambridge, MassachusettsThis individual will operate with a high degree of independence, scientific judgment, and cross-functional influence while partnering with antigen design, structural and computational biology, Immuno-oncology and Autoimmune Therapeutics research leadership, project teams, and external CRO partners. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
NewBioinformatician I Brigham and Women's HospitalBioinformatician IBoston, MA$75,275.20–$109,553.60 / yearThe Talkowski Laboratory in the Center for Genomic Medicine at Massachusetts General Hospital (MGH) and the Broad Institute of MIT and Harvard is seeking a highly motivated, enthusiastic Bioinformatics Specialist to work with and support our research group in analyzing sequencing data to identify structural variants within the human genome using genomic population databases and aggregating phenotype and genotype datasets. Working under very general supervision, the Bioinformatics Analyst will have demonstrated independent design and innovation in one or more of the following areas of specialization: algorithm development, data analysis, quality assurance/testing, pipeline software/computing development, user interface design & report development, web-based application development, or report development.
Sr. Scientist, Immune Repertoire Discovery Moderna IncSr. Scientist, Immune Repertoire DiscoveryCambridge, MA$130,800–$209,400 / yearWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. This is a highly collaborative, hands-on role for a scientist who is excited to build and refine discovery workflows, generate high-quality biological datasets, and translate complex immune profiling results into actionable insights for therapeutic research.
Microbiome Computational Scientist Brigham and Women's HospitalMicrobiome Computational ScientistBoston, MA$93,953.60–$136,739.20 / yearWith recent funding from the Massachusetts Life Sciences Center, the Lab has built a state-of-the-art compute cluster with extensive GPU and CPU nodes, with the objective of making advanced deep learning technologies broadly available to microbiome researchers. Applications will include forecasting microbial population dynamics in the gut, characterizing the impact of spatial structure of the microbiome, predicting impact of the microbiome on host phenotype, tracking infections in human populations, elucidating microbial metabolism, and discovering functions of uncharacterized microbial metabolites and proteins.
Director, Oncology Data Science Merck & Co IncDirector, Oncology Data ScienceBoston, MA$194,100–$305,600 / yearRequired Skills: Bioinformatics, Cancer Genomics, Cancer Research, Computational Biology, Computational Methods, Data Science, Deep Learning, High Dimensional Data Analysis, Immuno-Oncology, Machine Learning (ML), Multimodal Analysis, Oncology, Real World Data, Statistical Learning. Analyze, summarize and visualize the findings from large multi-modal clinico-genomic datasets which include bulk RNAseq, WES/WGS, imaging, epigenetic profiling, single-cell RNAseq, and proteomics data from oncology clinical trials and real-world datasets.
Senior Director - Biointelligence Amgen Inc.Senior Director - BiointelligenceCambridge, MAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. This role requires a leader with deep expertise in machine learning for biological systems, experience building and mentoring high-performing scientific teams, and a track record of translating advanced computational methods into impactful research capabilities.
Associate Director, Functional Genomics, Data Science Merck & Co IncAssociate Director, Functional Genomics, Data ScienceCambridge, MA$176,200–$277,300 / yearRequired Skills: Amazon Web Services (AWS), Bioinformatics, Biostatistics, Computer Science, CRISPR-Cas System, Data Engineering, Data Modeling, Data Science, Data Visualization, Genome, Genomics, Hypothesis Testing, Linux Environments, Machine Learning (ML), Model Fine-Tuning, Omics, Single-Cell Genomics, Software Development, Stakeholder Relationship Management, Statistical Design of Experiments (DOE), Statistical Programming. Integrate functional genomics and imaging derived results with high throughput transcriptomics and proteomics datasets to build multi evidence target prioritization packages for multiple stages of drug discovery.
NewScientist, Computational Sensing Flagship Pioneering IncScientist, Computational SensingCambridge, MA$115,000–$165,000 / yearMaster''s degree plus 3+ years of relevant industry experience, or PhD in Computational Biology, Biophysics, Bioengineering, Physics, Applied Mathematics, Computer Science, Electrical Engineering, or a related quantitative discipline. This role sits at the intersection of biology, physics, signal processing, and machine learning - you will work directly with experimental scientists and engineers to develop methods that transform complex biological measurements into actionable scientific insight.